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List of works by Dawn Quelle

A novel nuclear interactor of ARF and MDM2 (NIAM) that maintains chromosomal stability

scientific article

A porcine model of neurofibromatosis type 1 that mimics the human disease

scientific article published on 21 June 2018

ARF directly binds DP1: interaction with DP1 coincides with the G1 arrest function of ARF.

scientific article

ARF function does not require p53 stabilization or Mdm2 relocalization

scientific article published on January 2002

Alternative reading frames of the INK4a tumor suppressor gene encode two unrelated proteins capable of inducing cell cycle arrest

scientific article

Assessment of nociception and related quality-of-life measures in a porcine model of neurofibromatosis type 1

scientific article published on 01 November 2019

Cloning and characterization of murine p16INK4a and p15INK4b genes

scientific article published on August 17, 1995

Combination of Proteasome and Histone Deacetylase Inhibitors Overcomes the Impact of Gain-of-Function p53 Mutations

scientific article published on 17 December 2018

D-type cyclin-dependent kinase activity in mammalian cells

scientific article (publication date: March 1994)

D-type cyclins and their cyclin-dependent kinases: G1 phase integrators of the mitogenic response

scientific article

Deletion and altered regulation of p16INK4a and p15INK4b in undifferentiated mouse skin tumors

scientific article

Development and translational imaging of a TP53 porcine tumorigenesis model

scientific article

Dna damage-induced G(1) arrest in hematopoietic cells is overridden following phosphatidylinositol 3-kinase-dependent activation of cyclin-dependent kinase 2

scientific article

Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging

scientific article published in July 1997

Gene Expression Signatures Identify Novel Therapeutics for Metastatic Pancreatic Neuroendocrine Tumors

scientific article published on 14 January 2020

Generation and characterization of monoclonal antibodies to NIAM: a nuclear interactor of ARF and Mdm2.

scientific article

Immunohistochemical Markers for Prospective Studies in Neurofibromatosis-1 Porcine Models.

scientific article published on August 2017

Large-scale molecular comparison of human schwann cells to malignant peripheral nerve sheath tumor cell lines and tissues

scientific article

Localized cytosolic domains of the erythropoietin receptor regulate growth signaling and down-modulate responsiveness to granulocyte-macrophage colony-stimulating factor ⬇️

scientific article published on June 1, 1991

Mutations in the WSAWSE and cytosolic domains of the erythropoietin receptor affect signal transduction and ligand binding and internalization

scientific article published on October 1992

Myst2/Kat7 histone acetyltransferase interaction proteomics reveals tumour-suppressor Niam as a novel binding partner in embryonic stem cells

scientific article

NEK2 induces osteoclast differentiation and bone destruction via heparanase in multiple myeloma.

scientific article published on 12 April 2017

NIAM-deficient mice are predisposed to the development of proliferative lesions including B-cell lymphomas

scientific article

Nucleophosmin (B23) targets ARF to nucleoli and inhibits its function

scientific article published on February 2005

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts

scientific article published on August 1993

Phosphorylatable and epitope-tagged human erythropoietins: utility and purification of native baculovirus-derived forms

scientific article

Porcine cancer models for translational oncology

scientific article published on October 2014

RABL6A Promotes Oxaliplatin Resistance in Tumor Cells and Is a New Marker of Survival for Resected Pancreatic Ductal Adenocarcinoma Patients.

scientific article published on July 2013

RABL6A inhibits tumor-suppressive PP2A/AKT signaling to drive pancreatic neuroendocrine tumor growth

scientific article published on 04 March 2019

RABL6A is an essential driver of MPNSTs that negatively regulates the RB1 pathway and sensitizes tumor cells to CDK4/6 inhibitors

scientific article published on 21 February 2020

RABL6A promotes G1-S phase progression and pancreatic neuroendocrine tumor cell proliferation in an Rb1-dependent manner

scientific article

RABL6A, a novel RAB-like protein, controls centrosome amplification and chromosome instability in primary fibroblasts.

scientific article

RGS6 suppresses Ras-induced cellular transformation by facilitating Tip60-mediated Dnmt1 degradation and promoting apoptosis.

scientific article

Radiomic biomarkers informative of cancerous transformation in neurofibromatosis-1 plexiform tumors

scientific article published on 27 June 2018

Residues in the alternative reading frame tumor suppressor that influence its stability and p53-independent activities

scientific article published on 27 January 2009

Respiratory syncytial virus decreases p53 protein to prolong survival of airway epithelial cells.

scientific article

The ARF tumor suppressor inhibits tumor cell colonization independent of p53 in a novel mouse model of pancreatic ductal adenocarcinoma metastasis.

scientific article

The t(8;21) fusion protein, AML1 ETO, specifically represses the transcription of the p14(ARF) tumor suppressor in acute myeloid leukemia

scientific article published on 24 June 2002

Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF

scientific article (publication date: 28 November 1997)

p53 Acetylation: Regulation and Consequences

scientific article

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