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List of works by Francesca Ceccherini-Silberstein

'Sentinel' mutations in standard population sequencing can predict the presence of HIV-1 reverse transcriptase major mutations detectable only by ultra-deep pyrosequencing.

scientific article published on 2 September 2011

2019 update of the drug resistance mutations in HIV-1

scientific article published on 01 September 2019

A Hyper-Glycosylation of HBV Surface Antigen Correlates with HBsAg-Negativity at Immunosuppression-Driven HBV Reactivation in Vivo and Hinders HBsAg Recognition in Vitro

scientific article published on 23 February 2020

A boceprevir failure in a patient infected with HCV genotype 1g: importance and limitations of virus genotyping prior to HCV protease-inhibitor-based therapy

scientific article published on 15 February 2013

A snapshot of virological presentation and outcome of immunosuppression-driven HBV reactivation from real clinical practice: Evidence of a relevant risk of death and evolution from silent to chronic infection

scientific article published on 14 May 2019

A very low geno2pheno false positive rate is associated with poor viro-immunological response in drug-naïve patients starting a first-line HAART

scientific article

Access and response to direct antiviral agents (DAA) in HIV-HCV co-infected patients in Italy: Data from the Icona cohort

scientific article

Analysis of nuclear targeting activities of transport signals in the human immunodeficiency virus Rev protein

scientific article

Anti-HBV treatment induces novel reverse transcriptase mutations with reflective effect on HBV S antigen

scientific article published on 22 June 2013

Characterisation of HIV-1 molecular transmission clusters among newly diagnosed individuals infected with non-B subtypes in Italy

scientific article published on 10 May 2019

Characteristics of hepatitis C virus resistance in an international cohort after a decade of direct-acting antivirals

scientific article published on 24 February 2022

Characterization and structural analysis of HIV-1 integrase conservation

scientific article published on January 2009

Characterization and structural analysis of novel mutations in human immunodeficiency virus type 1 reverse transcriptase involved in the regulation of resistance to nonnucleoside inhibitors

scientific article

Characterization of drug-resistance mutations in HIV type 1 isolates from drug-naive and ARV-treated patients in Bulgaria

scientific article

Characterization of the patterns of drug-resistance mutations in newly diagnosed HIV-1 infected patients naïve to the antiretroviral drugs

scientific article

Clinical and genotypic correlates of mutation K65R in HIV-infected patients failing regimens not including tenofovir

article

Comparative analysis of drug resistance among B and the most prevalent non-B HIV type 1 subtypes (C, F, and CRF02_AG) in Italy

scientific article

Comparative antiviral activity of integrase inhibitors in human monocyte-derived macrophages and lymphocytes.

scientific article published on 16 August 2011

Comparative replication capacity of raltegravir-resistant strains and antiviral activity of the new-generation integrase inhibitor dolutegravir in human primary macrophages and lymphocytes

scientific article published on 23 May 2014

Computational analysis of Human Immunodeficiency Virus (HIV) Type-1 reverse transcriptase crystallographic models based on significant conserved residues found in Highly Active Antiretroviral Therapy (HAART)-treated patients

scientific article published on January 2010

Consequences of inaccurate hepatitis C virus genotyping on the costs of prescription of direct antiviral agents in an Italian district

scientific article published on 14 September 2016

Corrigendum to "Hepatitis C virus drug resistance associated substitutions and their clinical relevance: Update 2018" [Drug Resist. Updates 37 (March) (2018) 17-39].

scientific article published on 18 April 2018

Cryptic HBV Replicative Activity Is Frequently Revealed in Anti-HBc-Positive/HBsAg-Negative Patients with HIV Infection by Highly Sensitive Molecular Assays, and Can Be Predicted by Integrating Classical and Novel Serological HBV Markers

scientific article published on 18 November 2020

Death rates in HIV-positive antiretroviral-naive patients with CD4 count greater than 350 cells per microL in Europe and North America: a pooled cohort observational study

scientific article

Description of the L76V resistance protease mutation in HIV-1 B and "non-B" subtypes

scientific article

Development of a definition for Rapid Progression (RP) of renal function in HIV-positive persons: the D:A:D study

scientific article

Different Patterns of HIV-1 Replication in MACROPHAGES is Led by Co-Receptor Usage

scientific article published on 21 June 2019

Different evolution of genotypic resistance profiles to emtricitabine versus lamivudine in tenofovir-containing regimens

scientific article published on November 2010

Different kinetics of viral replication and DNA integration in the main HIV-1 cellular reservoirs in the presence and absence of integrase inhibitors

scientific article published on 26 October 2018

Docking analysis and resistance evaluation of clinically relevant mutations associated with the HIV-1 non-nucleoside reverse transcriptase inhibitors nevirapine, efavirenz and etravirine

scientific article published on 27 September 2011

Durability of lopinavir/ritonavir dual-therapies in individuals with viral load <50 copies/mL in the observational setting

scientific article

Dynamics of NRTI Resistance Mutations during Therapy Interruption

article

Effect of the human immunodeficiency virus type 1 reverse transcriptase polymorphism Leu-214 on replication capacity and drug susceptibility.

scientific article published on 20 May 2009

Effectiveness of dolutegravir-based regimens as either first-line or switch antiretroviral therapy: data from the Icona cohort

Efficacy and safety of sofosbuvir/simeprevir plus flat dose ribavirin in genotype 1 elderly cirrhotic patients: A real-life study

scientific article

Emerging patterns and implications of HIV-1 integrase inhibitor resistance

scientific article published on December 2012

European recommendations for the clinical use of HIV drug resistance testing: 2011 update

scientific article published on April 1, 2011

Evaluation of Circulating and Archived HIV-1 Integrase Drug-Resistance Variants among Patients on Third-Line ART in Cameroon: Implications for Dolutegravir-Containing Regimens in Resource-Limited Settings

scientific article published in 2022

Evaluation of HIV Transmission Clusters among Natives and Foreigners Living in Italy

scientific article published on 23 July 2020

Evaluation of virological response and resistance profile in HIV-1 infected patients starting a first-line integrase inhibitor-based regimen in clinical settings

scientific article published on 11 July 2020

Evidence of Spontaneous Post-transplant HCV Eradication in Two Failed DAA Treatments Awaiting Liver Transplantation

scientific article published on 12 May 2017

Evolution of HIV-1 tropism at quasispecies level after 5 years of combination antiretroviral therapy in patients always suppressed or experiencing episodes of virological failure

scientific article published on 10 July 2014

Exploring resistance pathways for first-generation NS3/4A protease inhibitors boceprevir and telaprevir using Bayesian network learning

scientific article published on 09 May 2017

Failure on voxilaprevir, velpatasvir, sofosbuvir and efficacy of rescue therapy

scientific article published on 18 November 2020

Focus on recently developed assays for detection of resistance/sensitivity to reverse transcriptase inhibitors

scientific article published on 29 September 2018

Frequent NS5A and multiclass resistance in almost all HCV genotypes at DAA failures: What are the chances for second-line regimens?

scientific article

From current status to optimization of HCV treatment: Recommendations from an expert panel

scientific article published on 15 June 2016

Genetic and structural analysis of HIV-1 Rev responsive element related to V38A and T18A enfuvirtide resistance mutations

scientific article published on 21 December 2011

Genetic divergence of HIV-1 B subtype in Italy over the years 2003-2016 and impact on CTL escape prevalence

scientific article published in Scientific Reports

Genotypic Tropism Testing in HIV-1 Proviral DNA Can Provide Useful Information at Low-Level Viremia

scientific article

Genotypic resistance test in proviral DNA can identify resistance mutations never detected in historical genotypic test in patients with low level or undetectable HIV-RNA.

scientific article published on 18 July 2016

HCV genotypes are differently prone to the development of resistance to linear and macrocyclic protease inhibitors

scientific article

HCV resistance compartmentalization within tumoral and non-tumoral liver in transplanted patients with hepatocellular carcinoma

scientific article published on 16 July 2019

HCV very late relapse following an atypical viral kinetics in a HIV patient treated for hepatitis C with direct-acting antivirals

article

HCV-RNA quantification in liver bioptic samples and extrahepatic compartments, using the abbott RealTime HCV assay

scientific article published on 10 April 2017

HDV Can Constrain HBV Genetic Evolution in HBsAg: Implications for the Identification of Innovative Pharmacological Targets

scientific article published on 09 July 2018

HHV-8 genetic diversification and its impact on severe clinical presentation of associated diseases

scientific article published on 13 April 2020

HIV fitness and resistance as covariates associated with the appearance of mutations under antiretroviral treatment.

scientific article published in January 2003

HIV-1 Drug Susceptibility to Potential Second- and Third-Line Antiretroviral Regimens among Cameroonian Patients: Evidence from a Cross-sectional Design

scientific article published on 29 December 2016

HIV-1 Drug Susceptibility to Potential Second- and Third-Line Antiretroviral Regimens among Cameroonian Patients: Evidence from a Crosssectional Design

article

HIV-1 co-receptor tropism and liver fibrosis in HIV-infected patients

scientific article published on 11 January 2018

HIV-1 drug resistance testing is essential for heavily-treated patients switching from first- to second-line regimens in resource-limited settings: evidence from routine clinical practice in Cameroon

article

HIV-1 dual/mixed tropic isolates show different genetic and phenotypic characteristics and response to maraviroc in vitro

scientific article

HIV-1 integrase resistance associated mutations and the use of dolutegravir in Sub-Saharan Africa: a systematic review and meta-analysis protocol

scientific article published on 25 April 2020

HIV-2 A-subtype gp125c₂-v₃-c₃ mutations and their association with CCR5 and CXCR4 tropism.

scientific article

HIV-Infected Late Presenter Patients

scientific article published on 29 November 2011

Hepatitis C virus RNA levels at week-2 of telaprevir/boceprevir administration are predictive of virological outcome

scientific article published on 24 November 2014

Hepatitis C virus drug resistance associated substitutions and their clinical relevance: Update 2018.

scientific article published on 21 February 2018

Hepatitis C virus gene sequencing as a tool for precise genotyping in the era of new direct antiviral agents

scientific article published on 14 May 2015

High sequence conservation of human immunodeficiency virus type 1 reverse transcriptase under drug pressure despite the continuous appearance of mutations

scientific article

Historical resistance profile helps to predict salvage failure.

scientific article published on January 2009

Identification and structural characterization of novel genetic elements in the HIV-1 V3 loop regulating coreceptor usage

scientific article published in January 2011

Identification of a novel Rev-interacting cellular protein

scientific article

Identification of a rare mutation at reverse transcriptase Lys65 (K65E) in HIV-1-infected patients failing on nucleos(t)ide reverse transcriptase inhibitors

scientific article published on 7 June 2013

Identification of gp120 polymorphisms in HIV-1 B subtype potentially associated with resistance to fostemsavir

scientific article published on 11 March 2020

Identification of the minimal conserved structure of HIV-1 protease in the presence and absence of drug pressure.

scientific article

Immune activation and microbial translocation in liver disease progression in HIV/hepatitis co-infected patients: results from the Icona Foundation study

scientific article

Impact of HCV genotype on treatment regimens and drug resistance: a snapshot in time

scientific article

Impact of HIV-1 reverse transcriptase polymorphism F214L on virological response to thymidine analogue-based regimens in antiretroviral therapy (ART)-naive and ART-experienced patients

scientific article published on 19 September 2007

Impact of pre-therapy viral load on virological response to modern first-line HAART.

scientific article published on 23 January 2013

Implications of hepatitis C virus subtype 1a migration patterns for virus genetic sequencing policies in Italy

scientific article

Improvement of ALT decay kinetics by all-oral HCV treatment: Role of NS5A inhibitors and differences with IFN-based regimens

scientific article

Incidence and predictors of single drug discontinuation according to the presence of HCV coinfection in HIV patients from the ICONA Foundation Cohort Study

scientific article published on 9 January 2018

Incomplete APOBEC3G/F Neutralization by HIV-1 Vif Mutants Facilitates the Genetic Evolution from CCR5 to CXCR4 Usage

scientific article published on 8 June 2015

Inhibition of dual/mixed tropic HIV-1 isolates by CCR5-inhibitors in primary lymphocytes and macrophages.

scientific article

Integrase inhibitor (INI) genotypic resistance in treatment-naive and raltegravir-experienced patients infected with diverse HIV-1 clades

scientific article

Integrase strand transfer inhibitor-based regimen is related with a limited HIV-1 V3 loop evolution in clinical practice

scientific article published on 22 February 2019

Involvement of novel human immunodeficiency virus type 1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors

scientific article

Is the rate of virological failure to cART continuing to decline in recent calendar years?

scientific article published on 03 May 2019

Is there any potential for first-line etravirine use? Analysis from a large data set of antiretroviral therapy-naive HIV-infected patients undergoing resistance test

scientific article published in January 2010

Key genetic elements, single and in clusters, underlying geographically dependent SARS-CoV-2 genetic adaptation and their impact on binding affinity for drugs and immune control

scientific article published on 30 November 2020

Key mutations in the C-terminus of the HBV surface glycoprotein correlate with lower HBsAg levels in vivo, hinder HBsAg secretion in vitro and reduce HBsAg structural stability in the setting of HBeAg-negative chronic HBV genotype-D infection

scientific article published on 20 April 2020

Kinetics of hepatitis C virus RNA decay, quasispecies evolution and risk of virological failure during telaprevir-based triple therapy in clinical practice

scientific article published on 27 December 2014

Lamivudine-resistance mutations can be selected even at very low levels of hepatitis B viraemia

scientific article published on 19 June 2010

Limited development and progression of resistance of HIV-1 to the nucleoside analogue reverse transcriptase inhibitor lamivudine in human primary macrophages

scientific article published on 21 April 2005

Long-Term SARS-CoV-2 Infection Associated with Viral Dissemination in Different Body Fluids Including Bile in Two Patients with Acute Cholecystitis

scientific article published on 23 November 2020

Longitudinal analysis of HIV-1 coreceptor tropism by single and triplicate HIV-1 RNA and DNA sequencing in patients undergoing successful first-line antiretroviral therapy

scientific article published on 23 October 2013

Low-frequency drug-resistant HIV-1 and risk of virological failure to first-line NNRTI-based ART: a multicohort European case-control study using centralized ultrasensitive 454 pyrosequencing

scientific article

May some HCV genotype 1 patients still benefit from dual therapy? The role of very early HCV kinetics

scientific article published on 20 October 2015

Molecular Diversity of HIV in Albania

article

Molecular and structural aspects of clinically relevant mutations related to the approved non-nucleoside inhibitors of HIV-1 reverse transcriptase

scientific article published on 03 February 2011

Molecular dynamics and free energy studies on the wild-type and mutated HIV-1 protease complexed with four approved drugs: mechanism of binding and drug resistance.

scientific article

Multiclass HCV resistance to direct-acting antiviral failure in real-life patients advocates for tailored second-line therapies

scientific article

Mutations in HIV-1 reverse transcriptase potentially associated with hypersusceptibility to nonnucleoside reverse-transcriptase inhibitors: effect on response to efavirenz-based therapy in an urban observational cohort

scientific article published on 13 April 2004

NS5A Gene Analysis by Next Generation Sequencing in HCV Nosocomial Transmission Clusters of HCV Genotype 1b Infected Patients

scientific article published on 02 July 2019

New raltegravir resistance pathways induce broad cross-resistance to all currently used integrase inhibitors

scientific article published on 7 April 2014

New resistance mutations to nucleoside reverse transcriptase inhibitors at codon 184 of HIV-1 reverse transcriptase (M184L and M184T)

scientific article published on 27 November 2018

Next-generation sequencing provides an added value in determining drug resistance and viral tropism in Cameroonian HIV-1 vertically infected children.

scientific article published in March 2018

Non-AIDS defining cancers in the D:A:D Study--time trends and predictors of survival: a cohort study

scientific article

Novel HBsAg markers tightly correlate with occult HBV infection and strongly affect HBsAg detection

article

Novel HBsAg mutations correlate with hepatocellular carcinoma, hamper HBsAg secretion and promote cell proliferation in vitro.

scientific article published on February 2017

Novel drug resistance mutations in HIV: recognition and clinical relevance

scientific article published on October 2006

Novel human immunodeficiency virus type 1 protease mutations potentially involved in resistance to protease inhibitors

scientific article

Novelties in Evaluation and Monitoring of Human Immunodeficiency Virus-1 Infection: Is Standard Virological Suppression Enough for Measuring Antiretroviral Treatment Success?

scientific article published on 19 September 2017

Novelties in evaluation and monitoring of HIV-1 infection: Is standard virological suppression enough for measuring antiretroviral treatment success?

article

Occupational HIV Infection in a Research Laboratory With Unknown Mode of Transmission: A Case Report

scientific article

Ombitasvir, paritaprevir, and ritonavir, with or without dasabuvir, plus ribavirin for patients with hepatitis C virus genotype 1 or 4 infection with cirrhosis (ABACUS): a prospective observational study

scientific article published on 10 April 2017

Optimal cure rate by personalized HCV regimens in real-life: a proof-of-concept study

scientific article published on 18 September 2017

Overlapping structure of hepatitis B virus (HBV) genome and immune selection pressure are critical forces modulating HBV evolution

scientific article published on 10 October 2012

Performance of genotypic tropism testing in clinical practice using the enhanced sensitivity version of Trofile as reference assay: results from the OSCAR Study Group

scientific article

Performance of genotypic tropism testing on proviral DNA in clinical practice: results from the DIVA study group.

scientific article published on 10 January 2012

Pre-ART HIV-1 DNA in CD4+ T cells correlates with baseline viro-immunological status and outcome in patients under first-line ART

article

Prevalence of Single and Multiple Natural NS3, NS5A and NS5B Resistance-Associated Substitutions in Hepatitis C Virus Genotypes 1-4 in Italy.

scientific article

Prevalence of doravirine-associated resistance mutations in HIV-1-infected antiretroviral-experienced patients from two large databases in France and Italy

scientific article published on 01 April 2020

Prevalence of resistance mutations related to integrase inhibitor S/GSK1349572 in HIV-1 subtype B raltegravir-naive and -treated patients

article

Prevalence of resistance-associated substitutions and retreatment of patients failing a glecaprevir/pibrentasvir regimen

scientific article published on 08 August 2020

Quantification of HIV-DNA and residual viremia in patients starting ART by droplet digital PCR: Their dynamic decay and correlations with immunological parameters and virological success

scientific article published on 14 June 2019

Rapid prediction of sustained virological response in patients chronically infected with HCV by evaluation of RNA decay 48h after the start of treatment with pegylated interferon and ribavirin

scientific article published on 11 August 2010

Rare occurrence of doravirine resistance-associated mutations in HIV-1-infected treatment-naive patients

article

Real life experiences in HCV management in 2018

scientific article published on 15 January 2019

Recent Transmission Clustering of HIV-1 C and CRF17_BF Strains Characterized by NNRTI-Related Mutations among Newly Diagnosed Men in Central Italy

scientific article

Refining criteria for selecting candidates for a safe lopinavir/ritonavir or darunavir/ritonavir monotherapy in HIV-infected virologically suppressed patients

scientific article

Reliability and clinical relevance of the HIV-1 drug resistance test in patients with low viremia levels

scientific article published on 14 January 2014

Research news in clincal context

scientific article published on 01 May 2020

Research news in clinical context

scientific article published on 01 November 2020

Resistance detected in PBMCs predicts virological rebound in HIV-1 suppressed patients switching treatment

scientific article published on 03 April 2018

Resistance to new antiretrovirals (ETV, anti-integrases, entry inhibitors).

scientific article published on 11 May 2010

Resistance to novel drug classes

scientific article

Role of hepatitis B virus genetic barrier in drug-resistance and immune-escape development

scientific article published on 9 August 2011

Secondary integrase resistance mutations found in HIV-1 minority quasispecies in integrase therapy-naive patients have little or no effect on susceptibility to integrase inhibitors.

scientific article

Selected amino acid changes in HIV-1 subtype-C gp41 are associated with specific gp120(V3) signatures in the regulation of co-receptor usage

scientific article published on 23 June 2012

Selected amino acid mutations in HIV-1 B subtype gp41 are associated with specific gp120v₃ signatures in the regulation of co-receptor usage

scientific article

Sequencing of hepatitis C virus for detection of resistance to direct-acting antiviral therapy: A systematic review.

scientific article published on 22 May 2017

Short Communication: Population-Based Surveillance of HIV-1 Drug Resistance in Cameroonian Adults Initiating Antiretroviral Therapy According to the World Health Organization Guidelines

scientific article

Specific HIV-1 integrase polymorphisms change their prevalence in untreated versus antiretroviral-treated HIV-1-infected patients, all naive to integrase inhibitors

scientific article published on 3 September 2010

Specific enfuvirtide-associated mutational pathways in HIV-1 Gp41 are significantly correlated with an increase in CD4(+) cell count, despite virological failure

scientific article published in May 2008

Structural modifications induced by specific HIV-1 protease-compensatory mutations have an impact on the virological response to a first-line lopinavir/ritonavir-containing regimen

scientific article published on 17 May 2013

Study of genotypic and phenotypic HIV-1 dynamics of integrase mutations during raltegravir treatment: a refined analysis by ultra-deep 454 pyrosequencing

scientific article published on 11 January 2012

Subtype analysis and mutations to antiviral drugs in HIV-1-infected patients from Mozambique before initiation of antiretroviral therapy: results from the DREAM programme

scientific article

Successful ongoing retreatment with glecaprevir/pibrentasvir+sofosbuvir+ribavirin in a patient with HCV genotype 3 who failed glecaprevir/pibrentasvir with both NS3 and NS5A resistance

scientific article published on 30 March 2020

Switch of predicted HIV-1 tropism in treated subjects and its association with disease progression

scientific article published on November 2016

Temporal characterization of drug resistance associated mutations in HIV-1 protease and reverse transcriptase in patients failing antiretroviral therapy

article

The Food Additive Maltodextrin Promotes Endoplasmic Reticulum Stress-Driven Mucus Depletion and Exacerbates Intestinal Inflammation

scientific article published on 11 September 2018

The HIV-1 integrase G118R mutation confers raltegravir resistance to the CRF02_AG HIV-1 subtype.

scientific article published on 19 September 2011

The HIV-1 reverse transcriptase polymorphism A98S improves the response to tenofovir disoproxil fumarate+emtricitabine-containing HAART both in vivo and in vitro

scientific article published on 25 July 2016

The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs

scientific article

The V118I mutation as a marker of advanced HIV infection and disease progression

article

The amino acid Asn136 in HIV-1 reverse transcriptase (RT) maintains efficient association of both RT subunits and enables the rational design of novel RT inhibitors

scientific article published on 15 April 2005

The genotypic false positive rate determined by V3 population sequencing can predict the burden of HIV-1 CXCR4-using species detected by pyrosequencing

scientific article

The multifactorial pathways towards resistance to the cytosine analogues emtricitabine and lamivudine: evidences from literature

scientific article published on 15 May 2014

The need for a European hepatitis C programme monitoring resistance to direct-acting antiviral agents in real life to eliminate hepatitis C

The profile of mutational clusters associated with lamivudine resistance can be constrained by HBV genotypes

scientific article published on 18 October 2008

The role of Thr139 in the human immunodeficiency virus type 1 reverse transcriptase sensitivity to (+)-calanolide A.

scientific article

Total HIV-1 DNA detection and quantification in peripheral blood by COBAS®AmpliPrep/COBAS® TaqMan® HIV-1 Test, v2.0.

scientific article published on 24 September 2015

Treatment of Acute Hepatitis C With Ledipasvir and Sofosbuvir in Patients With Hematological Malignancies Allows Early Re-start of Chemotherapy

scientific article published on 2 November 2017

Treatment with the fusion inhibitor enfuvirtide influences the appearance of mutations in the human immunodeficiency virus type 1 regulatory protein rev.

scientific article published on 05 January 2009

Trends and correlates of HIV-1 resistance among subjects failing an antiretroviral treatment over the 2003-2012 decade in Italy

scientific article

Ultradeep sequencing detection of the R263K integrase inhibitor drug resistance mutation

scientific article published on 14 January 2017

Understanding HIV compartments and reservoirs

scientific article published on June 2014

Use of novel antiretroviral agents in rescue regimens: a case of early virological failure to raltegravir

scientific article published in March 2010

Very high pre-therapy viral load is a predictor of virological rebound in HIV-1-infected patients starting a modern first-line regimen

scientific article published on 01 January 2019

Viral resistance in HCV infection

scientific article published on 01 October 2018

Virologic correlates of adherence to antiretroviral medications and therapeutic failure.

scientific article

Virological response to salvage therapy in HIV-infected persons carrying the reverse transcriptase K65R mutation

scientific article published in January 2007

Whole exome HBV DNA integration is independent of the intrahepatic HBV reservoir in HBeAg-negative chronic hepatitis B

scientific article published on 21 December 2020