List of works - Stephen C. Harmer

A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P₂.

scientific article published on 6 January 2013

Ajmaline blocks INa and IKr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters.

scientific article published on 7 November 2017

CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy

scientific article published on 01 November 2018

Cellular mechanisms underlying the increased disease severity seen for patients with long QT syndrome caused by compound mutations in KCNQ1.

scientific article published in August 2014

Characterization of a binding site for anionic phospholipids on KCNQ1.

scientific article published on 17 November 2010

GFRA2 Identifies Cardiac Progenitors and Mediates Cardiomyocyte Differentiation in a RET-Independent Signaling Pathway.

scientific article published on 5 July 2016

Generation of kisspeptin-responsive GnRH neurons from human pluripotent stem cells.

scientific article published on 20 February 2017

Genetic variants in TRPM7 associated with unexplained stillbirth modify ion channel function

scientific article published on 19 August 2019

Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop.

scientific article

Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant

scientific article published on 02 November 2021

Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D

scientific article published on 18 March 2019

K+ channels in the heart: new insights and therapeutic implications

scientific article published on 01 May 2010

Lys-gamma3-MSH: a global regulator of hormone sensitive lipase activity?

scientific article published on 14 October 2008

Mechanisms of disease pathogenesis in long QT syndrome type 5

scientific article

Molecular mechanisms of congenital hyperinsulinism due to autosomal dominant mutations in ABCC8.

scientific article

Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking

scientific article published on 11 October 2017

Postmortem Genetic Testing for Cardiac Ion Channelopathies in Stillbirths

scientific article published on 11 January 2018

Readthrough of long-QT syndrome type 1 nonsense mutations rescues function but alters the biophysical properties of the channel.

scientific article published on May 2012

The control of cardiac ventricular excitability by autonomic pathways.

scientific article published on 13 February 2017

The impact of recent advances in genetics in understanding disease mechanisms underlying the long QT syndromes.

scientific article published on 23 February 2016

The role of abnormal trafficking of KCNE1 in long QT syndrome 5.

scientific article published on November 2007

The role of the melanocortin 3 receptor in mediating the effects of gamma-MSH peptides on the adrenal

scientific article published on 01 November 2004

List of works by Stephen C. Harmer

A basic residue in the proximal C-terminus is necessary for efficient activation of the M-channel subunit Kv7.2 by PI(4,5)P₂.

Ajmaline blocks INa and IKr without eliciting differences between Brugada syndrome patient and control human pluripotent stem cell-derived cardiac clusters.

CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy

Cellular mechanisms underlying the increased disease severity seen for patients with long QT syndrome caused by compound mutations in KCNQ1.

Characterization of a binding site for anionic phospholipids on KCNQ1.

GFRA2 Identifies Cardiac Progenitors and Mediates Cardiomyocyte Differentiation in a RET-Independent Signaling Pathway.

Generation of kisspeptin-responsive GnRH neurons from human pluripotent stem cells.

Genetic variants in TRPM7 associated with unexplained stillbirth modify ion channel function

Human-based approaches to pharmacology and cardiology: an interdisciplinary and intersectorial workshop.

Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant

Investigating the Complex Arrhythmic Phenotype Caused by the Gain-of-Function Mutation KCNQ1-G229D

K+ channels in the heart: new insights and therapeutic implications

Lys-gamma3-MSH: a global regulator of hormone sensitive lipase activity?

Mechanisms of disease pathogenesis in long QT syndrome type 5

Molecular mechanisms of congenital hyperinsulinism due to autosomal dominant mutations in ABCC8.

Phosphatidylinositol-4,5-bisphosphate is required for KCNQ1/KCNE1 channel function but not anterograde trafficking

Postmortem Genetic Testing for Cardiac Ion Channelopathies in Stillbirths

Readthrough of long-QT syndrome type 1 nonsense mutations rescues function but alters the biophysical properties of the channel.

The control of cardiac ventricular excitability by autonomic pathways.

The impact of recent advances in genetics in understanding disease mechanisms underlying the long QT syndromes.

The role of abnormal trafficking of KCNE1 in long QT syndrome 5.

The role of the melanocortin 3 receptor in mediating the effects of gamma-MSH peptides on the adrenal