List of works by Christopher J. Wilds

2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H

scientific article published on April 2006

AGT Activity Towards Intrastrand Crosslinked DNA is Modulated by the Alkylene Linker

scientific article published on 5 October 2017

Accommodation of mispair aligned N3T-ethyl-N3T DNA interstrand cross link

scientific article published in October 2004

Covalent capture of OGT's active site using engineered human-E. coli chimera and intrastrand DNA cross-links

scientific article published on 01 November 2018

Covalent incorporation of selenium into oligonucleotides for X-ray crystal structure determination via MAD: proof of principle. Multiwavelength anomalous dispersion

scientific article

Cross-link structure affects replication-independent DNA interstrand cross-link repair in mammalian cells

scientific article

Crystal Structure of Homo-DNA and Nature's Choice of Pentose over Hexose in the Genetic System

scientific article published on 01 August 2006

Crystal structure of a B-form DNA duplex containing (L)-alpha-threofuranosyl (3'-->2') nucleosides: a four-carbon sugar is easily accommodated into the backbone of DNA

scientific article

Effect of cross-link structure on DNA interstrand cross-link repair synthesis

scientific article published on July 2009

Effect of linker length on DNA duplexes containing a mismatched O6-2'-deoxyguanosine-alkyl interstrand cross-link

scientific article

Interdomain allostery promotes assembly of the poly(A) mRNA complex with PABP and eIF4G

scientific article

Internal derivatization of oligonucleotides with selenium for X-ray crystallography using MAD

scientific article published on 01 January 2002

Intrastrand base-stacking buttresses widening of major groove in interstrand cross-linked B-DNA.

scientific article published in July 2005

Lesion Orientation of O4-Alkylthymidine Influences Replication by Human DNA Polymerase η.

scientific article published on 26 April 2016

Mispair-aligned N3T-alkyl-N3T interstrand cross-linked DNA: synthesis and characterization of duplexes with interstrand cross-links of variable lengths

scientific article

N(4)C-alkyl-N(4)C cross-linked DNA: bending deformations in duplexes that contain a -CNG- interstrand cross-link

scientific article published in July 2002

N(4)C-ethyl-N(4)C cross-linked DNA: synthesis and characterization of duplexes with interstrand cross-links of different orientations

scientific article published on 01 January 2002

NMR structure of an ethylene interstrand cross-linked DNA which mimics the lesion formed by 1,3-bis(2-chloroethyl)-1-nitrosourea

scientific article

O(6) -alkylguanine-DNA alkyltransferase-mediated repair of O(4) -alkylated 2'-deoxyuridines.

scientific article published on August 2014

O(6)-Alkylguanine DNA Alkyltransferase Repair Activity Towards Intrastrand Cross-Linked DNA is Influenced by the Internucleotide Linkage.

scientific article

O4 -Alkylated-2-Deoxyuridine Repair by O6 -Alkylguanine DNA Alkyltransferase is Augmented by a C5-Fluorine Modification

scientific article published on 15 December 2017

O6-2'-Deoxyguanosine-butylene-O6-2'-deoxyguanosine DNA Interstrand Cross-Links Are Replication-Blocking and Mutagenic DNA Lesions

scientific article published on 21 October 2016

Preparation of Intrastrand {G}O(6) -Alkylene-O(6) {G} Cross-Linked Oligonucleotides.

scientific article published in September 2016

Preparation of covalently linked complexes between DNA and O(6)-alkylguanine-DNA alkyltransferase using interstrand cross-linked DNA.

scientific article published on 24 January 2013

Properties of arabinonucleic acids (ANA & 20'F-ANA): implications for the design of antisense therapeutics that invoke RNase H cleavage of RNA.

scientific article

RNA-Binding affinities and crystal structure of oligonucleotides containing five-atom amide-based backbone structures.

scientific article published on July 2006

Reductively-sheddable cationic nanocarriers for dual chemotherapy and gene therapy with enhanced release.

scientific article published on 18 December 2014

Repair of O6-G-alkyl-O6-G interstrand cross-links by human O6-alkylguanine-DNA alkyltransferase.

scientific article published on 20 September 2008

Sequence-dependent nanometer-scale conformational dynamics of individual RecBCD-DNA complexes

scientific article published on 24 May 2016

Site-specific covalent capture of human O6-alkylguanine-DNA-alkyltransferase using single-stranded intrastrand cross-linked DNA.

scientific article published on 25 November 2016

Solution structure of an arabinonucleic acid (ANA)/RNA duplex in a chimeric hairpin: comparison with 2'-fluoro-ANA/RNA and DNA/RNA hybrids

scientific article

Stabilization of i-motif structures by 2'-β-fluorination of DNA.

scientific article published on 10 May 2016

Structural basis of interstrand cross-link repair by O6-alkylguanine DNA alkyltransferase

scientific article published on 22 September 2017

Structure of the parallel duplex of poly(A) RNA: evaluation of a 50 year-old prediction

scientific article

Structure, flexibility, and repair of two different orientations of the same alkyl interstrand DNA cross-link.

scientific article

Studies of a chemically modified oligodeoxynucleotide containing a 5-atom amide backbone which exhibits improved binding to RNA.

scientific article published on April 2001

Synthesis and biophysical properties of arabinonucleic acids (ANA): circular dichroic spectra, melting temperatures, and ribonuclease H susceptibility of ANA.RNA hybrid duplexes.

scientific article

Synthesis and characterization of DNA containing an N1-2'-deoxyinosine-ethyl-N3-thymidine interstrand cross-link: a structural mimic of the cross-link formed by 1,3-bis-(2-chloroethyl)-1-nitrosourea

scientific article published on 8 February 2008

Synthesis and characterization of DNA duplexes containing an N3T-ethyl-N3T interstrand crosslink in opposite orientations

scientific article

Synthesis and characterization of an O(6)-2'-deoxyguanosine-alkyl-O(6)-2'-deoxyguanosine interstrand cross-link in a 5'-GNC motif and repair by human O(6)-alkylguanine-DNA alkyltransferase

scientific article published on 13 August 2010

Synthesis of building blocks and oligonucleotides containing {T}O4-alkylene-O4{T} interstrand cross-links.

scientific article

Synthesis of building blocks and oligonucleotides with {G}O⁶-alkyl-O⁶{G} cross-links

scientific article published on 01 March 2011

Synthesis of building blocks and oligonucleotides with {T}N3-alkylene-N3{T} cross-links

scientific article published on 01 December 2012

Synthesis, Characterization, and Repair of a Flexible O(6) -2'-Deoxyguanosine-alkylene-O(6) -2'-deoxyguanosine Intrastrand Cross-Link.

scientific article

Synthesis, biophysical and repair studies of O6-2'-deoxyguanosine adducts by Escherichia coli OGT.

scientific article

The influence of cytosine methylation on the chemoselectivity of benzo[a]pyrene diol epoxide-oligonucleotide adducts determined using nanoLC/MS/MS.

scientific article published on August 2009

The solution structure of double helical arabino nucleic acids (ANA and 2'F-ANA): effect of arabinoses in duplex-hairpin interconversion

scientific article

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