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List of works by Alexandra Mazharian

A novel method for automated assessment of megakaryocyte differentiation and proplatelet formation.

scientific article published on 20 February 2018

Accessible Synthetic Probes for Staining Actin inside Platelets and Megakaryocytes by Employing Lifeact Peptide.

scientific article

Assessment of Megakaryocyte Migration and Chemotaxis

scientific article published on 01 January 2012

Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions

scientific article published on 01 December 2019

Collagen type I degradation fragments act through the collagen receptor LAIR-1 to provide a negative feedback for osteoclast formation

scientific article published on 12 September 2018

Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice

scientific article published on 13 June 2018

Critical role for ERK1/2 in bone marrow and fetal liver-derived primary megakaryocyte differentiation, motility, and proplatelet formation

scientific article published on 18 July 2009

Critical role of Src-Syk-PLC{gamma}2 signaling in megakaryocyte migration and thrombopoiesis.

scientific article

Cross talk between serine/threonine and tyrosine kinases regulates ADP-induced thromboxane generation in platelets.

scientific article

Dasatinib enhances megakaryocyte differentiation but inhibits platelet formation

scientific article

Differential Involvement of ERK2 and p38 in Platelet Adhesion to Collagen

scientific article published on 25 April 2005

Heparan sulfates are critical regulators of the inhibitory megakaryocyte-platelet receptor G6b-B

scientific article published on 22 August 2019

Involvement of the Mitogen-activated Protein Kinase c-Jun NH2-terminal Kinase 1 in Thrombus Formation

scientific article published on 04 September 2007

JAK2V617F leads to intrinsic changes in platelet formation and reactivity in a knock-in mouse model of essential thrombocythemia

scientific article published on October 2013

LAIR-1 Limits Neutrophilic Airway Inflammation

scientific article published on 26 April 2019

Maintenance of murine platelet homeostasis by the kinase Csk and the phosphatase CD148.

scientific article published on 4 January 2018

Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function

scientific article

Mice Lacking the Inhibitory Collagen Receptor LAIR-1 Exhibit a Mild Thrombocytosis and Hyperactive Platelets.

scientific article published on 23 March 2017

Mice lacking the ITIM-containing receptor G6b-B exhibit macrothrombocytopenia and aberrant platelet function

scientific journal article

Proplatelets slip slidin' away

scientific article published on 01 January 2015

Protease-activating Receptor-4 Induces Full Platelet Spreading on a Fibrinogen Matrix

scientific article published on 02 January 2007

Sphingosine kinase 2 (Sphk2) regulates platelet biogenesis by providing intracellular sphingosine 1-phosphate (S1P).

scientific article

Src family kinases: at the forefront of platelet activation

scientific article published on 12 August 2014

TREM-like transcript 1: a more sensitive marker of platelet activation than P-selectin in humans and mice

scientific article published on 01 August 2018

The transgenic mouse: a new model to delineate platelet and leukocyte functions

scientific article published on 14 November 2018

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis

scientific journal article

Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis

scientific article published on 11 June 2018

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