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List of works by Andrew R. Hesketh

A novel method for improving Streptomyces coelicolor A3(2) for production of actinorhodin by introduction of rpsL (encoding ribosomal protein S12) mutations conferring resistance to streptomycin

scientific article published on 01 June 1997

A panoramic view of the genomic landscape of the genus Streptomyces

scientific article published in 2023

A sporulation-specific, sigF-dependent protein, SspA, affects septum positioning in Streptomyces coelicolor.

scientific article published on 19 December 2013

Aerial development in Streptomyces coelicolor requires sortase activity

scientific article published on 8 February 2012

Bacterial Signaling Nucleotides Inhibit Yeast Cell Growth by Impacting Mitochondrial and Other Specifically Eukaryotic Functions.

scientific article

Biosynthesis of trichothecene mycotoxins: cell-free epoxidation of a trichodiene derivative

scientific article published on 01 July 1991

Carprofen-induced depletion of proton motive force reverses TetK-mediated doxycycline resistance in methicillin-resistant Staphylococcus pseudintermedius

scientific article published on 28 November 2019

Chapter 4. Analyzing the regulation of antibiotic production in streptomycetes

scientific article published in January 2009

Characterisation of a natural variant of the γ-butyrolactone signalling receptor

scientific article

Chemotranscriptomic Profiling Defines Drug-Specific Signatures of the Glycopeptide Antibiotics Dalbavancin, Vancomycin and Chlorobiphenyl-Vancomycin in a VanB-Type-Resistant Streptomycete

scientific article published on 25 February 2021

Cholinergic neuron gene expression differences captured by translational profiling in a mouse model of Alzheimer's disease

scientific article published on 25 May 2017

Cloning and analysis of the planosporicin lantibiotic biosynthetic gene cluster of Planomonospora alba.

scientific article

Complex extracellular interactions of proteases and a protease inhibitor influence multicellular development of Streptomyces coelicolor

scientific journal article

Cross-platform transcriptomic profiling of the response to recombinant human erythropoietin

scientific article published on 04 November 2021

Determination of the Global Pattern of Gene Expression in Yeast Cells by Intracellular Levels of Guanine Nucleotides

article

Effects of growth phase and the developmentally significant bldA-specified tRNA on the membrane-associated proteome of Streptomyces coelicolor

scientific article published on 01 August 2005

Elucidation of Focal Adhesion Kinase as a Modulator of Migration and Invasion and as a Potential Therapeutic Target in Chronic Lymphocytic Leukemia

scientific article published on 22 March 2022

Evidence from proteomics that some of the enzymes of actinorhodin biosynthesis have more than one form and may occupy distinctive cellular locations

scientific article published on 10 July 2003

Expression analysis of the ssgA gene product, associated with sporulation and cell division in Streptomyces griseus

scientific article published in April 1997

Functional analysis of relA and rshA, two relA/spoT homologues of Streptomyces coelicolor A3(2).

scientific article

Genome-wide dynamics of a bacterial response to antibiotics that target the cell envelope

scientific article

High-Resolution Mass Spectrometry Based Proteomic Analysis of the Response to Vancomycin-Induced Cell Wall Stress in Streptomyces coelicolor A3(2).

scientific article published on 29 May 2015

High-energy guanine nucleotides as a signal capable of linking growth to cellular energy status via the control of gene transcription

scientific article published on 01 April 2019

In vivo studies suggest that induction of VanS-dependent vancomycin resistance requires binding of the drug to D-Ala-D-Ala termini in the peptidoglycan cell wall

scientific article published on 8 July 2013

Induction of actinorhodin production by rpsL (encoding ribosomal protein S12) mutations that confer streptomycin resistance in Streptomyces lividans and Streptomyces coelicolor A3(2).

scientific article published on December 1996

Induction of ppGpp synthesis in Streptomyces coelicolor A3(2) grown under conditions of nutritional sufficiency elicits actII-ORF4 transcription and actinorhodin biosynthesis.

scientific article

Investigating the physiological response of Pichia (Komagataella) pastoris GS115 to the heterologous expression of misfolded proteins using chemostat cultures

scientific article published on 11 September 2013

Microarray Analysis to Monitor Bacterial Cell Wall Homeostasis

scientific article

Molecular and functional analyses of the gene (eshA) encoding the 52-kilodalton protein of Streptomyces coelicolor A3(2) required for antibiotic production.

scientific article

Molecular and functional analysis of the ribosomal L11 and S12 protein genes (rplK and rpsL) of Streptomyces coelicolor A3(2)

scientific journal article

Novel mechanism of glycopeptide resistance in the A40926 producer Nonomuraea sp. ATCC 39727.

scientific article published on 22 March 2010

PEDRo: a database for storing, searching and disseminating experimental proteomics data

scientific article

Phenomic and transcriptomic analyses reveal that autophagy plays a major role in desiccation tolerance in Saccharomyces cerevisiae.

scientific article

RNA Sequencing Best Practices: Experimental Protocol and Data Analysis

scientific article published on 01 January 2019

Streptomyces clavuligerus relA-null mutants overproduce clavulanic acid and cephamycin C: negative regulation of secondary metabolism by (p)ppGpp

scientific article

Stress hormone-mediated acceleration of breast cancer metastasis is halted by inhibition of nitric oxide synthase

scientific article published on 24 May 2019

Synthetic RNA Silencing of Actinorhodin Biosynthesis in Streptomyces coelicolor A3(2).

scientific article

The GlnD and GlnK homologues of Streptomyces coelicolor A3(2) are functionally dissimilar to their nitrogen regulatory system counterparts from enteric bacteria.

scientific article

The frontline antibiotic vancomycin induces a zinc starvation response in bacteria by binding to Zn(II).

scientific article

The role of absC, a novel regulatory gene for secondary metabolism, in zinc-dependent antibiotic production in Streptomyces coelicolor A3(2).

scientific article published on 10 November 2009

Transcriptome analysis of extended-spectrum β-lactamase-producing Escherichia coli and methicillin-resistant Staphylococcus aureus exposed to cefotaxime

scientific article published in Scientific Reports

Translational control plays an important role in the adaptive heat-shock response of Streptomyces coelicolor.

scientific article published in June 2018

Zn(II) mediates vancomycin polymerization and potentiates its antibiotic activity against resistant bacteria

scientific article published on 7 July 2017