Search filters

List of works by Cris Constantinescu

'Importance sampling' in MS: use of diffusion tensor tractography to quantify pathology related to specific impairment.

scientific article published in October 2005

A case of dysphagia with clinically isolated syndrome

scientific article published on 18 April 2008

A comparative audit of anticardiolipin antibodies in oligoclonal band negative and positive multiple sclerosis

scientific article published on 01 August 2005

A comparison of phase imaging and quantitative susceptibility mapping in the imaging of multiple sclerosis lesions at ultrahigh field

scientific article published on 25 April 2016

A different response to cytomegalovirus (CMV) and Epstein-Barr virus (EBV) infection in UK people with multiple sclerosis (PwMS) compared to controls

scientific article published on 31 October 2019

A drug discovery case history of 'delta-9-tetrahydrocannabinol, cannabidiol'.

scientific article published on 3 March 2011

A longitudinal study of the T cell activation marker CD26 in chronic progressive multiple sclerosis

scientific article published on 01 June 1995

A presenilin 1 mutation (Arg278Ser) associated with early onset Alzheimer's disease and spastic paraparesis

scientific article

A prospective study of conditions associated with multiple sclerosis in a cohort of 658 consecutive outpatients attending a multiple sclerosis clinic

scientific article published on 01 October 2004

A regularized two-tensor model fit to low angular resolution diffusion images using basis directions

scientific article published in July 2008

Absence of electromyographically detectable acute neuromuscular transmission defects after intramuscular interferon-gamma administration.

scientific article published in June 1998

Advances in the treatment of relapsing-remitting multiple sclerosis

scientific article published on March 2014

An Absence of Epstein-Barr Virus Reactivation and Associations with Disease Activity in People with Multiple Sclerosis Undergoing Therapeutic Hookworm Vaccination

scientific article published on 28 August 2020

Are current disease-modifying therapeutics in multiple sclerosis justified on the basis of studies in experimental autoimmune encephalomyelitis?

scientific article

Association of a deficit of arousal with fatigue in multiple sclerosis: effect of modafinil.

scientific article published on 2 July 2012

Astrocytes and microglia produce interleukin-12 p40

scientific article published on 01 October 1996

Astrocytes as antigen-presenting cells: expression of IL-12/IL-23

scientific article published on 08 August 2005

Atopic optic neuritis

scientific article published on 01 April 2006

Brain tractography using Q-ball imaging and graph theory: Improved connectivities through fibre crossings via a model-based approach

scientific article published on 8 October 2009

Cannabinoid receptor agonists are mitochondrial inhibitors: a unified hypothesis of how cannabinoids modulate mitochondrial function and induce cell death

scientific article

Cannabinoids and experimental models of multiple sclerosis.

scientific article

Cannabinoids and the immune system: an overview

scientific article published on 04 January 2010

Captopril and lisinopril suppress production of interleukin-12 by human peripheral blood mononuclear cells

scientific article published in May 1998

Central inflammation versus peripheral regulation in multiple sclerosis

scientific article published on 9 March 2011

Clinical and subclinical neurological involvement in children of conjugal multiple sclerosis patients

scientific article published on 01 November 1995

Cognitive Rehabilitation for Attention and Memory in people with Multiple Sclerosis: study protocol for a randomised controlled trial (CRAMMS).

scientific article

Cognitive rehabilitation for attention and memory in people with multiple sclerosis: a randomized controlled trial (CRAMMS)

scientific article published on 26 November 2019

Combined pharmacologic and surgical approach to acquired nystagmus due to multiple sclerosis

scientific article (publication date: November 2002)

Comorbidity in multiple sclerosis: its temporal relationships with disease onset and dose effect on mortality

scientific article published on 31 July 2019

Concurrence of multiple sclerosis and amyotrophic lateral sclerosis in patients with hexanucleotide repeat expansions of C9ORF72.

scientific article published on 20 October 2012

Congenital monocular elevation deficiency associated with a novel TUBB3 gene variant

scientific article published on 13 July 2019

Coordinate based meta-analysis does not show grey matter atrophy in narcolepsy

scientific article published on 05 November 2016

Coordinate based meta-analysis does not show grey matter atrophy in narcolepsy.

scientific article published on 22 September 2015

Coordinate based meta-analysis of functional neuroimaging data using activation likelihood estimation; full width half max and group comparisons

scientific article

Coordinate based meta-analysis of functional neuroimaging data; false discovery control and diagnostics

scientific article

Corpus callosum changes following shunting for hydrocephalus: case report and review of the literature.

scientific article

Cost-Effectiveness of Disease-Modifying Therapies in Multiple Sclerosis ⬇️

scientific article published on October 1, 2012

Curcumin modulation of IFN-beta and IL-12 signalling and cytokine induction in human T cells

scientific article

Cytokines in idiopathic intracranial hypertension CSF

scientific article published on 21 December 2009

DAB389IL-2 recombinant fusion toxin effect on lymphocyte- and macrophage-producing cytokine subpopulation cells in experimentally induced demyelinating disease in mice

scientific article published on 20 September 2017

DAB389IL-2 suppresses autoimmune inflammation in the CNS and inhibits T cell-mediated lysis of glial target cells.

scientific article published on 17 July 2013

Decreased interferon-β induced STAT-4 activation in immune cells and clinical outcome in multiple sclerosis.

scientific article published on 5 December 2016

Deep gray matter and fatigue in MS: a T1 relaxation time study

scientific article published on 13 March 2006

Development of a simple and sensitive HPLC-UV method for the simultaneous determination of cannabidiol and Δ(9)-tetrahydrocannabinol in rat plasma.

scientific article published on 22 May 2015

Diagnosis and management of Neuro-Behçet's disease: international consensus recommendations

scientific article published on 24 December 2013

Diagnostic modalities in multiple sclerosis: perspectives in children.

scientific article published on March 2014

Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines

scientific article published on 15 August 2016

Disconnection as a mechanism for cognitive dysfunction in multiple sclerosis

scientific article

Discrepant effects of human interferon-gamma on clinical and immunological disease parameters in a novel marmoset model for multiple sclerosis.

scientific article published on 20 October 2011

Effect of DAB(389)IL-2 immunotoxin on the course of experimental autoimmune encephalomyelitis in Lewis rats.

scientific article published on 2 July 2007

Effects of cigarette smoke on immunity, neuroinflammation and multiple sclerosis

scientific article published on 09 October 2018

Effects of glucocorticoids on STAT4 activation in human T cells are stimulus-dependent.

scientific article

Effects of pro-inflammatory cytokines on cannabinoid CB1 and CB2 receptors in immune cells

scientific article

Effects of the angiotensin converting enzyme inhibitor captopril on experimental autoimmune encephalomyelitis

scientific article published on 01 August 1995

Ehlers-Danlos syndrome and multiple sclerosis: a possible association.

scientific article published on 21 January 2008

Epilepsy and associated mortality in patients with multiple sclerosis

scientific article published on 30 October 2018

Erratum: Corrigendum: Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus

scholarly article published in Nature Genetics

Evaluation of an adjustment group for people with multiple sclerosis and low mood: a randomized controlled trial

scientific article

Experimental allergic neuritis in the SJL/J mouse: induction of severe and reproducible disease with bovine peripheral nerve myelin and pertussis toxin with or without interleukin-12

scientific article published on 01 July 2000

Experimental autoimmune encephalomyelitis (EAE) as a model for multiple sclerosis (MS).

scientific article published on October 2011

Expression of activity-dependent neuroprotective protein in the immune system: possible functions and relevance to multiple sclerosis

scientific article

Extra-hippocampal subcortical limbic involvement predicts episodic recall performance in multiple sclerosis

scientific article

Eye movement involvement in Parry-Romberg Syndrome: a clinicopathologic case report

scientific article published on 01 July 2008

Fatigue in multiple sclerosis - a brief review.

scientific article published on 27 August 2012

Functionally relevant white matter degradation in multiple sclerosis: a tract-based spatial meta-analysis

scientific article published on 24 November 2014

Glucocorticoids increase CD4CD25 cell percentage and Foxp3 expression in patients with multiple sclerosis.

scientific article published on April 2009

Granulocyte-Macrophage Colony-Stimulating Factor as a Therapeutic Target in Multiple Sclerosis.

scientific article

Graph Theoretic Analysis of Brain Connectomics in Multiple Sclerosis: Reliability and Relationship with Cognition

scientific article published on 01 March 2020

Helicobacter pylori infection reduces disease severity in an experimental model of multiple sclerosis

scientific article

Helminth Therapy for MS.

scientific article

Histogram analysis of quantitative T1 and MT maps from ultrahigh field MRI in clinically isolated syndrome and relapsing-remitting multiple sclerosis.

scientific article

Hookworm Treatment for Relapsing Multiple Sclerosis: A Randomized Double-Blinded Placebo-Controlled Trial

scientific article published on 15 June 2020

Hypothalamic involvement assessed by T1 relaxation time in patients with relapsing-remitting multiple sclerosis

scientific article published on 7 December 2009

Hypothermia in Multiple Sclerosis: Beyond the Hypothalamus? A Case Report and Review of the Literature.

scientific article

IL-12 inhibits glucocorticoid-induced T cell apoptosis by inducing GMEB1 and activating PI3K/Akt pathway.

scientific article

IL-12 reverses the suppressive effect of the CD40 ligand blockade on experimental autoimmune encephalomyelitis (EAE).

scientific article published in December 1999

Impact of exposure to interferon beta-1a on outcomes in patients with relapsing-remitting multiple sclerosis: exploratory analyses from the PRISMS long-term follow-up study

scientific article

Improved white matter fiber tracking using stochastic labeling

scientific article published in October 2002

Increase in the iron content of the substantia nigra and red nucleus in multiple sclerosis and clinically isolated syndrome: a 7 Tesla MRI study

scientific article published on 20 May 2014

Increased IL-2 and Reduced TGF-β Upon T-Cell Stimulation are Associated with GM-CSF Upregulation in Multiple Immune Cell Types in Multiple Sclerosis

scientific article published on 18 July 2020

Increased iron accumulation occurs in the earliest stages of demyelinating disease: an ultra-high field susceptibility mapping study in Clinically Isolated Syndrome

scientific article

Increased levels of interleukins 2 and 17 in the cerebrospinal fluid of patients with idiopathic intracranial hypertension

scientific article published on 16 October 2013

Increased osteopontin levels in the cerebrospinal fluid of patients with multiple sclerosis

scientific article published on 01 May 2008

Interaction between cytokines, cannabinoids and the nervous system

scientific article published on 04 January 2010

Interleukin 15 stimulates production of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 by human peripheral blood mononuclear cells

scientific article published on 01 February 2001

Intrathecal gadolinium-enhanced magnetic resonance myelography in the detection of CSF leak

scientific article published in October 2006

Iron Rims as an Imaging Biomarker in MS: A Systematic Mapping Review

scientific article published on 18 November 2020

Laquinimod (ABR-215062) for the treatment of relapsing multiple sclerosis

scientific article

Localised Grey Matter Atrophy in Multiple Sclerosis and Clinically Isolated Syndrome-A Coordinate-Based Meta-Analysis, Meta-Analysis of Networks, and Meta-Regression of Voxel-Based Morphometry Studies

scientific article published on 30 October 2020

Long-term subcutaneous interferon beta-1a therapy in patients with relapsing-remitting MS.

scientific article published in September 2006

Lymphocyte-specific inducible expression of potassium channel beta subunits ⬇️

scientific article published on July 1, 1997

MOG-IgG-associated demyelination: focus on atypical features, brain histopathology and concomitant autoimmunity

scientific article published on 22 October 2019

MRI-Based Measurement of Brain Stem Cross-Sectional Area in Relapsing-Remitting Multiple Sclerosis

scientific article published on 19 April 2015

Magnetic resonance imaging of the cervical spinal cord in multiple sclerosis--a quantitative T1 relaxation time mapping approach

scientific article published in March 2003

Maintenance Intravenous Immunoglobulin Treatment for Multiple Sclerosis Coexisting with Ehlers-Danlos Syndrome and Muir-Torre Syndrome: A Case Study

scientific article published on 11 August 2020

Measurement of cervical spinal cord cross-sectional area by MRI using edge detection and partial volume correction.

scientific article published in March 2005

Measurement of spinal cord atrophy in multiple sclerosis

scientific article published in July 2004

Melanin, melatonin, melanocyte-stimulating hormone, and the susceptibility to autoimmune demyelination: a rationale for light therapy in multiple sclerosis.

scientific article

Methylprednisolone in combination with interferon beta-1a for relapsing-remitting multiple sclerosis (MECOMBIN study): a multicentre, double-blind, randomised, placebo-controlled, parallel-group trial

scientific article published on 9 June 2010

Migraine and Raynaud phenomenon: possible late complications of Kawasaki disease

scientific article published in March 2002

Mitochondrial changes in leukocytes of patients with optic neuritis

scientific article published on 29 August 2007

Modulation of regulatory T cells in health and disease: role of toll-like receptors.

scientific article published on June 2009

Modulation of susceptibility and resistance to an autoimmune model of multiple sclerosis in prototypically susceptible and resistant strains by neutralization of interleukin-12 and interleukin-4, respectively

scientific article published on 01 January 2001

Mortality in multiple sclerosis: meta-analysis of standardised mortality ratios

scientific article published on 2 May 2015

Multiple sclerosis course and clinical outcomes in patients with comorbid asthma: a survey study

scientific article published on 20 May 2015

Multiple sclerosis findings in the spinal cord.

scientific article

Multiple sclerosis, lymphoma and nasopharyngeal carcinoma: the central role of Epstein-Barr virus?

scientific article published on 25 November 2009

Multiple sclerosis-associated IL2RA polymorphism controls GM-CSF production in human TH cells

scientific article published on 3 October 2014

Multiple sclerosis: autoimmune associations in multiple sclerosis

scientific article published on 01 November 2010

Murine macrophages stimulated with central and peripheral nervous system myelin or purified myelin proteins release inflammatory products

scientific article published on 01 June 2000

Mutations in FRMD7, a newly identified member of the FERM family, cause X-linked idiopathic congenital nystagmus

scientific article

Nabiximols in the treatment of spasticity, pain and urinary symptoms due to multiple sclerosis

scientific article published on 07 September 2012

Neurofilament ELISA validation

scientific article published on 24 October 2009

Novel therapeutic approaches to autoimmune demyelinating disorders.

scientific article published on January 2011

Oral administration of cannabis with lipids leads to high levels of cannabinoids in the intestinal lymphatic system and prominent immunomodulation.

scientific article published on 6 November 2017

Orexin A (hypocretin-1) levels are not reduced while cocaine/amphetamine regulated transcript levels are increased in the cerebrospinal fluid of patients with multiple sclerosis: no correlation with fatigue and sleepiness

scientific article

Oscillopsia without nystagmus caused by head titubation in a patient with multiple sclerosis

scientific article published in June 2002

PEGylated IFNβ-1a in the treatment of multiple sclerosis.

scientific article published on 03 June 2015

Paediatric Multiple Sclerosis: Update on Diagnostic Criteria, Imaging, Histopathology and Treatment Choices

scientific article

Parasite immunomodulation in autoimmune disease: focus on multiple sclerosis

scientific article published on 01 September 2009

Pharmacokinetic evaluation of fingolimod for the treatment of multiple sclerosis

scientific article published on March 2014

Pharmacokinetic evaluation of nabiximols for the treatment of multiple sclerosis pain

scientific article published on 27 April 2013

Plasma endocannabinoid levels in multiple sclerosis

scientific article published on 20 August 2009

Platelet activating factor/platelet activating factor receptor pathway as a potential therapeutic target in autoimmune diseases.

scientific article published on July 2009

Prevalence of a history of prior varicella/herpes zoster infection in multiple sclerosis

scientific article published on 11 September 2017

Prognostic factors for long-term outcomes in relapsing-remitting multiple sclerosis

scientific article

Randomized controlled trial of Sativex to treat detrusor overactivity in multiple sclerosis.

scientific article

Randomized phase 1b trial of MOR103, a human antibody to GM-CSF, in multiple sclerosis

scientific article published on 21 May 2015

Recent developments in interferon-based therapies for multiple sclerosis

scientific article published on 6 April 2018

Reciprocal Regulation of Substance P and IL-12/IL-23 and the Associated Cytokines, IFNγ/IL-17: A Perspective on the Relevance of This Interaction to Multiple Sclerosis.

scientific article

Reciprocal effects of IFN-beta and IL-12 on STAT4 activation and cytokine induction in T cells

scientific article published on 09 March 2007

Reduced EDSS progression in multiple sclerosis patients treated with modafinil for three years or more compared to matched untreated subjects

scientific article published on 4 April 2012

Reduced Myelin Signal in Normal-appearing White Matter in Neuromyelitis Optica Measured by 7T Magnetic Resonance Imaging

scientific article published on 07 October 2019

Relationship between cannabinoids and the immune system. Special Issue 8, 2010 Introduction

scientific article published on 01 June 2010

Repeated subcutaneous injections of IL12/23 p40 neutralising antibody, ustekinumab, in patients with relapsing-remitting multiple sclerosis: a phase II, double-blind, placebo-controlled, randomised, dose-ranging study

scientific article

Role of oral teriflunomide in the management of multiple sclerosis.

scientific article published on 22 April 2013

SUNCT in multiple sclerosis

scientific article published on 01 July 2006

Serum uric acid levels in optic neuritis.

scientific article

Seven-Tesla Magnetization Transfer Imaging to Detect Multiple Sclerosis White Matter Lesions

scientific article published on 25 September 2017

Siponimod for the treatment of secondary progressive multiple sclerosis

scientific article published on 05 December 2018

Skeletal muscle myosin is the autoantigen for experimental autoimmune myositis

scientific article published on 01 June 2003

Smoking cessation and the reduction of disability progression in Multiple Sclerosis: a cohort study

scientific article published on 10 April 2017

Spinal cord imaging in multiple sclerosis.

scientific article

Stroop performance in multiple sclerosis: information processing, selective attention, or executive functioning?

scientific article published in September 2008

Subjective discomfort in children receiving 3 T MRI and experienced adults' perspective on children's tolerability of 7 T: a cross-sectional questionnaire survey

scientific article

Suppression of experimental autoimmune neuritis by phosphodiesterase inhibitor pentoxifylline.

scientific article published in November 1996

TLR2 stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function

scientific article published on 20 July 2011

TLR2 stimulation regulates the balance between regulatory T cell and Th17 function: a novel mechanism of reduced regulatory T cell function in multiple sclerosis.

scientific article published on 15 May 2015

Th17/Th1 phenotype in demyelinating disease

scientific article published on 4 January 2010

The Role of Osteopontin in Experimental Autoimmune Encephalomyelitis (EAE) and Multiple Sclerosis (MS) ⬇️

scientific article published on September 1, 2010

The association between human endogenous retroviruses and multiple sclerosis: A systematic review and meta-analysis

scientific article

The endocannabinoid system: a revolving plate in neuro-immune interaction in health and disease ⬇️

scientific article published on February 26, 2012

The essential role of T cells in multiple sclerosis: a reappraisal.

scientific article published on March 2014

The future of multiple sclerosis treatments.

scientific article published on 29 September 2016

The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2-3

scientific article (publication date: May 2001)

The relationship of brain and cervical cord volume to disability in clinical subtypes of multiple sclerosis: a three-dimensional MRI study

scientific article

Time- and Region-Specific Season of Birth Effects in Multiple Sclerosis in the United Kingdom

scientific article published on 27 June 2016

Tobacco smoking and disability progression in multiple sclerosis: United Kingdom cohort study.

scientific article published on 11 June 2013

Tobacco smoking and excess mortality in multiple sclerosis: a cohort study.

scientific article

Treatment of neuromyelitis optica with rituximab: retrospective analysis of 25 patients

scientific article

Tumor necrosis factor alpha and lymphotoxin alpha are not required for induction of acute experimental autoimmune encephalomyelitis.

scientific article

Upper cervical spinal cord cross-sectional area in relapsing remitting multiple sclerosis: application of a new technique for measuring cross-sectional area on magnetic resonance images

scientific article published on 01 July 2007

Use of combined conventional and quantitative MRI to quantify pathology related to cognitive impairment in multiple sclerosis.

scientific article published on 2 August 2007

What role does tobacco smoking play in multiple sclerosis disability and mortality? A review of the evidence

scientific article

fMRI analysis of active, passive and electrically stimulated ankle dorsiflexion.

scientific article

Paulina is supported by:

About Paulina

Help