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List of works by Claire M Lucas

A population study of imatinib in chronic myeloid leukaemia demonstrates lower efficacy than in clinical trials

scientific article published on 28 August 2008

BCR-ABL1 tyrosine kinase activity at diagnosis, as determined via the pCrkL/CrkL ratio, is predictive of clinical outcome in chronic myeloid leukaemia

scientific article published on 11 January 2010

CIP2A- and SETBP1-mediated PP2A inhibition reveals AKT S473 phosphorylation to be a new biomarker in AML

scientific article published on 01 May 2018

Cancerous inhibitor of PP2A (CIP2A) at diagnosis of chronic myeloid leukemia is a critical determinant of disease progression

scientific article published on 13 April 2011

Chronic myeloid leukemia patients with the e13a2 BCR-ABL fusion transcript have inferior responses to imatinib compared to patients with the e14a2 transcript.

scientific article published on 27 August 2009

Effective dasatinib uptake may occur without human organic cation transporter 1 (hOCT1): implications for the treatment of imatinib-resistant chronic myeloid leukemia

scientific article

High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia.

scientific article published on 29 February 2016

Low leukotriene B4 receptor 1 leads to ALOX5 downregulation at diagnosis of chronic myeloid leukemia

scientific article

Nilotinib concentration in cell lines and primary CD34(+) chronic myeloid leukemia cells is not mediated by active uptake or efflux by major drug transporters.

scientific article

Rapid diagnosis of chronic myeloid leukemia by flow cytometric detection of BCR-ABL1 protein

scientific article published on 5 May 2011

Second generation tyrosine kinase inhibitors prevent disease progression in high-risk (high CIP2A) chronic myeloid leukaemia patients.

scientific article published on 13 March 2015

The clinical significance of ABCC3 as an imatinib transporter in chronic myeloid leukaemia

scientific article published on 20 January 2014

c-Myc inhibition decreases CIP2A and reduces BCR-ABL1 tyrosine kinase activity in chronic myeloid leukemia

scientific article published on 6 February 2015

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