List of works - Theresa Coetzer

A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites

scientific article

A systematic review of pentacyclic triterpenes and their derivatives as chemotherapeutic agents against tropical parasitic diseases

scientific article published on 31 May 2016

An enzyme immunoassay for atractyloside, the nephrotoxin of Callilepis laureola (Impila)

scientific article published on 01 January 1990

Animal Rights and Animal Welfare

Anti-peptide antibodies differentiate between plasmodial lactate dehydrogenases

scientific article published on 20 January 2010

Anti-peptide antibodies to cathepsins B, L and D and type IV collagenase

article

Baboon (Papio ursinus) cathepsin L: purification, characterization and comparison with human and sheep cathepsin L.

scientific article

Binding and elution of serum glycoproteins from agarose

scientific article published on 01 January 1984

Characterisation of the activity and stability of single-chain cathepsin L and of proteolytically active cathepsin L/cystatin complexes

scientific article published in July 1992

Characterisation of the antitrypanosomal activity of peptidyl alpha-aminoalkyl phosphonate diphenyl esters.

scientific article

Characterization of a multicatalytic proteinase complex (20S proteasome) from Trypanosoma brucei brucei

scientific article published in June 1997

Disaccharidase presence and activities in a range of southern African frugivores

Effect of adjuvants on the humoral immune response to congopain in mice and cattle

scientific article

Evidence that serpin architecture intrinsically supports papain-like cysteine protease inhibition: engineering alpha(1)-antitrypsin to inhibit cathepsin proteases

scientific article

Identification of a catalytic exosite for complement component C4 on the serine protease domain of C1s.

scientific article published on August 2012

Improvements in the isolation of igy from the yolks of eggs laid by immunized hens

article by A Polson et al published January 1985 in Immunological Investigations

Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation

scientific article

Localisation of Acid Phosphatase Activity on the Surface of Bloodstream Forms of Trypanosoma congolense

scientific article published on 01 December 1996

Localization of an immunoinhibitory epitope of the cysteine proteinase, cathepsin L.

scientific article published in October 1992

Mature cathepsin L is substantially active in the ionic milieu of the extracellular medium.

scientific article published in December 1995

Modulation of the immunogenicity of the Trypanosoma congolense cysteine protease, congopain, through complexation with alpha(2)-macroglobulin

scientific article published on 24 June 2009

Molecular and biochemical characterization of a cathepsin B-like protease family unique to Trypanosoma congolense

scientific article published on 15 February 2008

Molecular determinants of the substrate specificity of the complement-initiating protease, C1r.

scientific article

Multiple domains of MASP-2, an initiating complement protease, are required for interaction with its substrate C4.

scientific article

Oligopeptidase B from Trypanosoma brucei, a new member of an emerging subgroup of serine oligopeptidases.

scientific article

Phylogenetic analysis of the polyprotein coding region of an infectious South African bursal disease virus (IBDV) strain.

scientific article

Plasmodium glyceraldehyde-3-phosphate dehydrogenase: A potential malaria diagnostic target.

scientific article published on 25 May 2017

Production of anti-peptide antibodies against trypanopain-Tb from Trypanosoma brucei brucei: effects of antibodies on enzyme activity against Z-Phe-Arg-AMC

article

Production of congopain, the major cysteine protease of Trypanosoma (Nannomonas) congolense, in Pichia pastoris reveals unexpected dimerisation at physiological pH.

scientific article published on 7 September 2010

Proteolytically active complexes of cathepsin L and a cysteine proteinase inhibitor; purification and demonstration of their formation in vitro.

scientific article

Purification and characterisation of a trypsin-like serine oligopeptidase from Trypanosoma congolense.

scientific article published in July 1999

Raising Antibodies in Chickens Against Primaquine, Pyrimethamine, Dapsone, Tetracycline, and Doxycycline

Raising antibodies in chickens against primaquine, pyrimethamine, dapsone, tetracycline, and doxycycline.

scientific article

Recombinant and native TviCATL from Trypanosoma vivax: Enzymatic characterisation and evaluation as a diagnostic target for animal African trypanosomosis

scientific article published on 07 July 2018

Recombinant expression and biochemical characterisation of two alanyl aminopeptidases of Trypanosoma congolense.

scientific article

The Drosophila retinoblastoma binding protein 6 family member has two isoforms and is potentially involved in embryonic patterning

scientific article published on 6 May 2015

The X-ray Crystal Structure of Mannose-binding Lectin-associated Serine Proteinase-3 Reveals the Structural Basis for Enzyme Inactivity Associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) Syndrome

scientific article

The amino acid sequences, structure comparisons and inhibition kinetics of sheep cathepsin L and sheep stefin B

article

The x-ray crystal structure of mannose-binding lectin-associated serine proteinase-3 reveals the structural basis for enzyme inactivity associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) syndrome.

scientific article published in September 2013

Trypanosoma brucei brucei oligopeptidase B null mutants display increased prolyl oligopeptidase-like activity

Trypanosome-derived oligopeptidase B is released into the plasma of infected rodents, where it persists and retains full catalytic activity

scientific article

List of works by Theresa Coetzer

A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites

A systematic review of pentacyclic triterpenes and their derivatives as chemotherapeutic agents against tropical parasitic diseases

An enzyme immunoassay for atractyloside, the nephrotoxin of Callilepis laureola (Impila)

Animal Rights and Animal Welfare

Anti-peptide antibodies differentiate between plasmodial lactate dehydrogenases

Anti-peptide antibodies to cathepsins B, L and D and type IV collagenase

Baboon (Papio ursinus) cathepsin L: purification, characterization and comparison with human and sheep cathepsin L.

Binding and elution of serum glycoproteins from agarose

Characterisation of the activity and stability of single-chain cathepsin L and of proteolytically active cathepsin L/cystatin complexes

Characterisation of the antitrypanosomal activity of peptidyl alpha-aminoalkyl phosphonate diphenyl esters.

Characterization of a multicatalytic proteinase complex (20S proteasome) from Trypanosoma brucei brucei

Disaccharidase presence and activities in a range of southern African frugivores

Effect of adjuvants on the humoral immune response to congopain in mice and cattle

Evidence that serpin architecture intrinsically supports papain-like cysteine protease inhibition: engineering alpha(1)-antitrypsin to inhibit cathepsin proteases

Identification of a catalytic exosite for complement component C4 on the serine protease domain of C1s.

Improvements in the isolation of igy from the yolks of eggs laid by immunized hens

Inhibitory activity of a heterochromatin-associated serpin (MENT) against papain-like cysteine proteinases affects chromatin structure and blocks cell proliferation

Localisation of Acid Phosphatase Activity on the Surface of Bloodstream Forms of Trypanosoma congolense

Localization of an immunoinhibitory epitope of the cysteine proteinase, cathepsin L.

Mature cathepsin L is substantially active in the ionic milieu of the extracellular medium.

Modulation of the immunogenicity of the Trypanosoma congolense cysteine protease, congopain, through complexation with alpha(2)-macroglobulin

Molecular and biochemical characterization of a cathepsin B-like protease family unique to Trypanosoma congolense

Molecular determinants of the substrate specificity of the complement-initiating protease, C1r.

Multiple domains of MASP-2, an initiating complement protease, are required for interaction with its substrate C4.

Oligopeptidase B from Trypanosoma brucei, a new member of an emerging subgroup of serine oligopeptidases.

Phylogenetic analysis of the polyprotein coding region of an infectious South African bursal disease virus (IBDV) strain.

Plasmodium glyceraldehyde-3-phosphate dehydrogenase: A potential malaria diagnostic target.

Production of anti-peptide antibodies against trypanopain-Tb from Trypanosoma brucei brucei: effects of antibodies on enzyme activity against Z-Phe-Arg-AMC

Production of congopain, the major cysteine protease of Trypanosoma (Nannomonas) congolense, in Pichia pastoris reveals unexpected dimerisation at physiological pH.

Proteolytically active complexes of cathepsin L and a cysteine proteinase inhibitor; purification and demonstration of their formation in vitro.

Purification and characterisation of a trypsin-like serine oligopeptidase from Trypanosoma congolense.

Raising Antibodies in Chickens Against Primaquine, Pyrimethamine, Dapsone, Tetracycline, and Doxycycline

Raising antibodies in chickens against primaquine, pyrimethamine, dapsone, tetracycline, and doxycycline.

Recombinant and native TviCATL from Trypanosoma vivax: Enzymatic characterisation and evaluation as a diagnostic target for animal African trypanosomosis

Recombinant expression and biochemical characterisation of two alanyl aminopeptidases of Trypanosoma congolense.

The Drosophila retinoblastoma binding protein 6 family member has two isoforms and is potentially involved in embryonic patterning

The X-ray Crystal Structure of Mannose-binding Lectin-associated Serine Proteinase-3 Reveals the Structural Basis for Enzyme Inactivity Associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) Syndrome

The amino acid sequences, structure comparisons and inhibition kinetics of sheep cathepsin L and sheep stefin B

The x-ray crystal structure of mannose-binding lectin-associated serine proteinase-3 reveals the structural basis for enzyme inactivity associated with the Carnevale, Mingarelli, Malpuech, and Michels (3MC) syndrome.

Trypanosoma brucei brucei oligopeptidase B null mutants display increased prolyl oligopeptidase-like activity

Trypanosome-derived oligopeptidase B is released into the plasma of infected rodents, where it persists and retains full catalytic activity