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List of works by James P Di Santo

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Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

scientific article
The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling.

scientific article
Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

scientific article
Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

scientific article
CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM

scientific article published in Nature
Innate lymphoid cells. Innate lymphoid cells: a new paradigm in immunology

scientific article published on 21 May 2015
Interferon gamma contributes to initiation of uterine vascular modification, decidual integrity, and uterine natural killer cell maturation during normal murine pregnancy

scientific article published in July 2000
In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells

scientific article published on 26 May 2008
Lineage Relationship Analysis of RORγt+Innate Lymphoid Cells

scientific article published in Science
RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

scientific article published on 20 February 2011
Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development

scientific article published in May 2010
Natural killer cell developmental pathways: a question of balance.

scientific article
A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127

article
Innate Lymphoid Cells: 10 Years On

scientific article published on 01 August 2018
IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors

scientific article
Identification of committed NK cell progenitors in adult murine bone marrow

scientific article
The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome

scientific article
Tyrosine kinase SYK: essential functions for immunoreceptor signalling

scientific article (publication date: March 2000)
IL-15 is an essential mediator of peripheral NK-cell homeostasis

scientific article published on 13 February 2003
Cellular senescence in human myoblasts is overcome by human telomerase reverse transcriptase and cyclin-dependent kinase 4: consequences in aging muscle and therapeutic strategies for muscular dystrophies

scientific article published on 8 June 2007
Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

scientific article published on July 2009
Regulation of Cytokine Secretion in Human CD127+ LTi-like Innate Lymphoid Cells by Toll-like Receptor 2

scientific article published on 04 November 2010
Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.

scientific article published on March 2017
Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain

scientific article published on 01 November 1998
Transcriptional regulation of innate lymphoid cell fate.

scientific article published on 12 June 2015
IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function.

scientific article
Gata3 drives development of RORγt+ group 3 innate lymphoid cells.

scientific article published on 13 January 2014
Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells

scientific article published on 03 June 2013
GATA-3 Promotes Maturation, IFN-γ Production, and Liver-Specific Homing of NK Cells

article
Intraembryonic, but Not Yolk Sac Hematopoietic Precursors, Isolated before Circulation, Provide Long-Term Multilineage Reconstitution

scientific article published on 01 September 2001
Pro-Thymocyte Expansion by c-kit and the Common Cytokine Receptor γ Chain Is Essential for Repertoire Formation

scientific article published on 01 March 1997
Debugging how bacteria manipulate the immune response.

scientific article published on February 2007
NKG2D triggers cytotoxicity in mouse NK cells lacking DAP12 or Syk family kinases.

scientific article published on 11 May 2003
Following the development of a CD4 T cell response in vivo: from activation to memory formation

scientific article published in August 1999
Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo

scientific article
Small bowel enteropathy: role of intraepithelial lymphocytes and of cytokines (IL-12, IFN-gamma, TNF) in the induction of epithelial cell death and renewal

scientific article published in February 1998
Natural killer cell activation in mice and men: different triggers for similar weapons?

scientific article
GATA-3 function in innate and adaptive immunity.

scientific article
CD11cloB220+ interferon-producing killer dendritic cells are activated natural killer cells

scientific article
In vivo myogenic potential of human CD133+ muscle-derived stem cells: a quantitative study

scientific article
Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development

article
The Natural Cytotoxicity Receptor NKp46 Is Dispensable for IL-22-Mediated Innate Intestinal Immune Defense against Citrobacter rodentium

scientific article published on 21 October 2009
Intravital Imaging Reveals Distinct Dynamics for Natural Killer and CD8+ T Cells during Tumor Regression

scientific article published on October 14, 2010
Enhancement of myogenic and muscle repair capacities of human adipose-derived stem cells with forced expression of MyoD.

scientific article
Characterization of the thymic IL-7 niche in vivo.

scholarly article
A Novel Immunodeficient Mouse Model-RAG2 gamma Cytokine Receptor Chain Double Mutants-Requiring Exogenous Cytokine Administration for Human Hematopoietic Stem Cell Engraftment Common

article
Ultrastructural Studies of Implantation Sites from Mice Deficient in Uterine Natural Killer Cells

scientific article published on 01 September 2000
Repopulation efficiencies of adult hepatocytes, fetal liver progenitor cells, and embryonic stem cell-derived hepatic cells in albumin-promoter-enhancer urokinase-type plasminogen activator mice

scientific article published on 28 August 2009
Interleukin-15-dependent NKp46+ innate lymphoid cells control intestinal inflammation by recruiting inflammatory monocytes.

scientific article published on 14 June 2012
Role of different T cell receptors in the development of pre-T cells.

scientific article

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