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List of works by James P Di Santo

A Guardian of T Cell Fate

scientific article published in Science

A New Immunodeficient Mouse Model for Human Myoblast Transplantation

article

A Novel Immunodeficient Mouse Model-RAG2 gamma Cytokine Receptor Chain Double Mutants-Requiring Exogenous Cytokine Administration for Human Hematopoietic Stem Cell Engraftment Common

article

A bispecific nanobody approach to leverage the potent and widely applicable tumor cytolytic capacity of Vγ9Vδ2-T cells.

scientific article published on 20 October 2017

A defining factor for natural killer cell development

article

A functional DC cross talk promotes human ILC homeostasis in humanized mice

scientific article published on 06 April 2017

A novel autoregulatory cytokine is required for the regulation of autoaggressive responses.

scientific article published on March 1990

A recessive form of hyper-IgE syndrome by disruption of ZNF341-dependent STAT3 transcription and activity

scientific article published on 01 June 2018

A thymic pathway of mouse natural killer cell development characterized by expression of GATA-3 and CD127

article

Accelerated thymopoiesis and improved T-cell responses in HLA-A2/-DR2 transgenic BRGS-based human immune system mice

scientific article published on 02 April 2019

Activation of peripheral CD8+T lymphocytes via CD28 plus CD2: Evidence for IL-2 gene transcription mediated by CD28 activation

article

An IL-1β-Dependent Switch in Innate Mucosal Immunity?

scientific article published on 01 June 2010

An Intestinal Inflammasome - The ILC3-Cytokine Tango.

scientific article

Animal models for arthritis: innovative tools for prevention and treatment

scientific article published on 30 May 2011

Antigen receptors in lymphoid cell development and lymphocyte activation

article

Are major histocompatibility complex molecules involved in the survival of naive CD4+ T cells?

scientific article

Autonomous and extrinsic regulation of thymopoiesis in human immune system (HIS) mice

scientific article

CD11cloB220+ interferon-producing killer dendritic cells are activated natural killer cells

scientific article

CD4+ T cells are not essential for control of early acute Cryptosporidium parvum infection in neonatal mice.

scientific article published on 31 January 2011

CD40 ligand mutations in X-linked immunodeficiency with hyper-IgM

scientific article published in Nature

Cellular senescence in human myoblasts is overcome by human telomerase reverse transcriptase and cyclin-dependent kinase 4: consequences in aging muscle and therapeutic strategies for muscular dystrophies

scientific article published on 8 June 2007

Characterization of the thymic IL-7 niche in vivo.

scholarly article

Combined deficiency in I B and I B reveals a critical window of NF- B activity in natural killer cell differentiation

scientific article published on 05 February 2004

Common cytokine receptor γ chain (γc)-deficient B cells persist in T cell-deficient γc mice and respond to a T-independent antigen

scientific article published on 01 June 2000

Comparative Analysis of Genetically Engineered Immunodeficient Mouse Strains as Recipients for Human Myoblast Transplantation

article

Competition within the early B-cell compartment conditions B-cell reconstitution after hematopoietic stem cell transplantation in nonirradiated recipients

article

Critical role for the common cytokine receptor gamma chain in intrathymic and peripheral T cell selection

scientific article

Cutting Edge: A dual role for type I IFNs during polyinosinic-polycytidylic acid-induced NK cell activation.

scientific article published in August 2011

Cutting Edge: Thymic NK Cells Develop Independently from T Cell Precursors

scientific article published on 01 October 2010

Cutting Edge: a thymocyte-thymic epithelial cell cross-talk dynamically regulates intrathymic IL-7 expression in vivo.

scientific article published on 3 May 2010

Cytokines: IL-21 joins the gamma(c)-dependent network?

scientific article (publication date: 6 March 2001)

Cytokines: shared receptors, distinct functions.

scientific article published on July 1997

Debugging how bacteria manipulate the immune response.

scientific article published on February 2007

Deregulated TCR alpha beta T cell population provokes extramedullary hematopoiesis in mice deficient in the common gamma chain

scientific article published in April 1997

Developmental options and functional plasticity of innate lymphoid cells.

scientific article published on 27 March 2017

Developmental programming of natural killer and innate lymphoid cells.

scientific article published on 13 March 2013

Dichotomous metabolic networks govern human ILC2 proliferation and function

scientific article published in 2021

Differential requirement for the transcription factor PU.1 in the generation of natural killer cells versus B and T cells

scientific article published on 01 May 2001

Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection

scientific article published on 01 September 2021

Distinguishing features of developing natural killer cells.

scientific article

Do CD8 effector cells need IL-7R expression to become resting memory cells?

scientific article

Dynamic behavior of NK cells during activation in lymph nodes

scientific article published on 10 August 2009

Early T cell receptor beta gene expression is regulated by the pre-T cell receptor-CD3 complex

scientific article

Ectopic expression of murine CD47 minimizes macrophage rejection of human hepatocyte xenografts in immunodeficient mice

scientific article published in October 2012

Effects of Exogenous IL-2 Administration on the Homeostasis of CD4+ T Lymphocytes

article

Efficient ex vivo gene transfer into non-human primate hepatocytes using HIV-1 derived lentiviral vectors

scientific article published on 2 May 2006

Endocytosis of the beta chain of interleukin-2 receptor requires neither interleukin-2 nor the gamma chain.

scientific article published on September 1994

Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor gamma chain

scientific article published on 01 November 1998

Enhancement of myogenic and muscle repair capacities of human adipose-derived stem cells with forced expression of MyoD.

scientific article

Epitope specificity and relative clonal abundance do not affect CD8 differentiation patterns during lymphocytic choriomeningitis virus infection

scientific article published on 2 September 2009

Essential, dose-dependent role for the transcription factor Gata3 in the development of IL-5+ and IL-13+ type 2 innate lymphoid cells

scientific article published on 03 June 2013

Extended Amplification In Vitro and Replicative Senescence: Key Factors Implicated in the Success of Human Myoblast Transplantation

scientific article published on 01 August 2003

Following the development of a CD4 T cell response in vivo: from activation to memory formation

scientific article published in August 1999

Functional CD47/signal regulatory protein alpha (SIRP(alpha)) interaction is required for optimal human T- and natural killer- (NK) cell homeostasis in vivo

scientific article

GATA-3 Promotes Maturation, IFN-γ Production, and Liver-Specific Homing of NK Cells

article

GATA-3 function in innate and adaptive immunity.

scientific article

GATA-3 promotes T-cell specification by repressing B-cell potential in pro-T cells in mice

scientific article published on 3 January 2013

Gamma c cytokines condition the progressive differentiation of CD4+ T cells

scholarly article

Gata3 drives development of RORγt+ group 3 innate lymphoid cells.

scientific article published on 13 January 2014

Gene therapy of severe combined immunodeficiencies.

scientific article

Generation of anti-human CD8β-specific antibodies using transfectants expressing mixed-species CD8 heterodimers ⬇️

scientific article published on July 26, 1991

Generation of functional hepatocytes from human embryonic stem cells under chemically defined conditions that recapitulate liver development

scientific article published in May 2010

Generation of human antigen-specific monoclonal IgM antibodies using vaccinated "human immune system" mice

scientific article (publication date: 4 October 2010)

Genetic studies in severe combined immunodeficiency.

scientific article published on September 1995

High efficacy of combined rituximab and gemcitabine on Epstein-Barr virus-associated human B-cell lymphoma obtained after Hodgkin's xenograft in immunodeficient mice

scientific article published in July 2006

Histological studies of gene-ablated mice support important functional roles for natural killer cells in the uterus during pregnancy

article

Human CD8 transgene regulation of HLA recognition by murine T cells ⬇️

scientific article published on November 1, 1995

Human IFN-γ immunity to mycobacteria is governed by both IL-12 and IL-23

scientific article published on 01 December 2018

Human myoblast engraftment is improved in laminin-enriched microenvironment

scientific article

Human thymopoiesis is influenced by a common genetic variant within the TCRA-TCRD locus

scientific article published on 01 September 2018

Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

scientific article published on July 2009

IL-15 is an essential mediator of peripheral NK-cell homeostasis

scientific article published on 13 February 2003

IL-15 transpresentation promotes both human T-cell reconstitution and T-cell–dependent antibody responses in vivo ⬇️

scientific article published on March 28, 2011

IL-1β regulates a novel myeloid-derived suppressor cell subset that impairs NK cell development and function.

scientific article

IL-22 is produced by γC-independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS-induced lethality

scientific article published on 14 March 2011

IL-7 Enhances Thymic Human T Cell Development in "Human Immune System" Rag2-/-IL-2R c-/- Mice without Affecting Peripheral T Cell Homeostasis

article

IL-7 and IL-15 independently program the differentiation of intestinal CD3-NKp46+ cell subsets from Id2-dependent precursors

scientific article

Identification of committed NK cell progenitors in adult murine bone marrow

scientific article

Identification of the earliest prethymic bipotent T/NK progenitor in murine fetal liver.

scientific article published in January 2002

IkappaBalpha/IkappaBepsilon deficiency reveals that a critical NF-kappaB dosage is required for lymphocyte survival.

scientific article

Immortalized Skin Fibroblasts Expressing Conditional MyoD as a Renewable and Reliable Source of Converted Human Muscle Cells to Assess Therapeutic Strategies for Muscular Dystrophies: Validation of an Exon-Skipping Approach to Restore Dystrophin in D

scholarly article by Soraya Chaouch published in July 2009

In vivo equilibrium of proinflammatory IL-17+ and regulatory IL-10+ Foxp3+ RORgamma t+ T cells

scientific article published on 26 May 2008

In vivo myogenic potential of human CD133+ muscle-derived stem cells: a quantitative study

scientific article

In vivo roles of receptor tyrosine kinases and cytokine receptors in early thymocyte development

article

Innate Lymphoid Cells: 10 Years On

scientific article published on 01 August 2018

Innate Lymphoid Cells: Of Precursors and Products…

scientific article published on 01 June 2014

Innate lymphoid cells. Innate lymphoid cells: a new paradigm in immunology

scientific article published on 21 May 2015

Interferon gamma contributes to initiation of uterine vascular modification, decidual integrity, and uterine natural killer cell maturation during normal murine pregnancy

scientific article published in July 2000

Interleukin signaling

scientific journal article

Interleukin-15-Dependent T-Cell-like Innate Intraepithelial Lymphocytes Develop in the Intestine and Transform into Lymphomas in Celiac Disease

scientific article published on 31 August 2016

Interleukin-15-dependent NKp46+ innate lymphoid cells control intestinal inflammation by recruiting inflammatory monocytes.

scientific article published on 14 June 2012

Interleukin-7 regulates adipose tissue mass and insulin sensitivity in high-fat diet-fed mice through lymphocyte-dependent and independent mechanisms

scientific article

Interleukin-7, a new cytokine targeting the mouse hypothalamic arcuate nucleus: role in body weight and food intake regulation.

scientific article

Interplay between alpha/beta and gamma interferons with B, T, and natural killer cells in the defense against herpes simplex virus type 1.

scientific article published on April 2004

Intraembryonic, but Not Yolk Sac Hematopoietic Precursors, Isolated before Circulation, Provide Long-Term Multilineage Reconstitution

scientific article published on 01 September 2001

Intrathymic Deletion of IL-7 Reveals a Contribution of the Bone Marrow to Thymic Rebound Induced by Androgen Blockade.

scientific article published on 10 January 2018

Intravital Imaging Reveals Distinct Dynamics for Natural Killer and CD8+ T Cells during Tumor Regression ⬇️

scientific article published on October 14, 2010

Isolation of a highly myogenic CD34-negative subset of human skeletal muscle cells free of adipogenic potential.

scientific article published in April 2010

Lactobacillus paracasei feeding improves immune control of influenza infection in mice.

scientific article published on 20 September 2017

Lineage Relationship Analysis of RORγt+Innate Lymphoid Cells

scientific article published in Science

Long-term controlled immortalization of a primate hepatic progenitor cell line after Simian virus 40 T-Antigen gene transfer.

scientific article

Loss of the pro-apoptotic BH3-only Bcl-2 family member Bim sustains B lymphopoiesis in the absence of IL-7.

scientific article published on 19 May 2009

Lymphoid development in mice with a targeted deletion of the interleukin 2 receptor gamma chain.

scientific article

Lymphotoxin-β receptor-independent development of intestinal IL-22-producing NKp46+ innate lymphoid cells

article

Microbial flora drives interleukin 22 production in intestinal NKp46+ cells that provide innate mucosal immune defense

scientific article

Mouse macrophage development in the absence of the common γ chain: defining receptor complexes responsible for IL-4 and IL-13 signaling

article

Multiple survival signals are delivered by dendritic cells to naive CD4+ T cells

scientific article published on 01 September 2005

Myf5 haploinsufficiency reveals distinct cell fate potentials for adult skeletal muscle stem cells

scientific article published on 24 February 2012

Myogenic cell proliferation and generation of a reversible tumorigenic phenotype are triggered by preirradiation of the recipient site

scientific article

NKG2D triggers cytotoxicity in mouse NK cells lacking DAP12 or Syk family kinases.

scientific article published on 11 May 2003

Natural cytotoxicity uncoupled from the Syk and ZAP-70 intracellular kinases

scientific article published on 11 February 2002

Natural killer cell activation in mice and men: different triggers for similar weapons?

scientific article

Natural killer cell developmental pathways: a question of balance.

scientific article

Natural killer cell-dependent apoptosis of peripheral murine hematopoietic progenitor cells in response to Fas cross-linking: involvement of tumor necrosis factor-alpha

article

Neutrophils mediate antibody-induced antitumor effects in mice.

scientific article published on 26 August 2013

Notch signaling in group 3 innate lymphoid cells modulates their plasticity

scientific article published on 3 May 2016

On the role of the common cytokine receptor gamma chain in B-cell vs. T-cell development.

scientific article published on September 1997

Ontogeny, function, and peripheral homeostasis of regulatory T cells in the absence of interleukin-7

scientific article published on 08 June 2006

Origin, trafficking, and intraepithelial fate of gut-tropic T cells.

scientific article published on 05 August 2013

Peyer's patch myeloid cells infection by signals through gp38 stromal cells and locks intestinal villus invasion

article

Phenotypic Cyclophosphamide Resistance in Mouse Myeloma Hybridomas

scientific article published on 01 August 1988

Phenotypic and Functional Plasticity of Murine Intestinal NKp46+ Group 3 Innate Lymphoid Cells

scientific article published on 22 April 2016

Phosphorylation and down-regulation of CD4 and CD8 in human CTLs and mouse L cells

scientific article

Pre-B cell receptor expression is necessary for thymic stromal lymphopoietin responsiveness in the bone marrow but not in the liver environment.

scholarly article

Pro-Thymocyte Expansion by c-kit and the Common Cytokine Receptor γ Chain Is Essential for Repertoire Formation

scientific article published on 01 March 1997

Probing Human NK Cell Biology Using Human Immune System (HIS) Mice.

scientific article published on 13 October 2015

Processing of the bovine spongiform encephalopathy-specific prion protein by dendritic cells

scientific article published on May 2006

Production of hepatitis B defective particles is dependent on liver status.

scientific article published on 2 June 2012

Proinflammatory macrophages enhance the regenerative capacity of human myoblasts by modifying their kinetics of proliferation and differentiation

scientific article published on 16 October 2012

RORγt+ innate lymphoid cells regulate intestinal homeostasis by integrating negative signals from the symbiotic microbiota

scientific article published on 20 February 2011

Regulation of Cytokine Secretion in Human CD127+ LTi-like Innate Lymphoid Cells by Toll-like Receptor 2

scientific article published on 04 November 2010

Reply to 'Alice Dautry' profile

scientific article

Reply to “TSLP-mediated fetal B lymphopoiesis?”

Repopulation efficiencies of adult hepatocytes, fetal liver progenitor cells, and embryonic stem cell-derived hepatic cells in albumin-promoter-enhancer urokinase-type plasminogen activator mice

scientific article published on 28 August 2009

Repopulation of athymic mouse liver by cryopreserved early human fetal hepatoblasts

scientific article published in December 2004

Role of an intact splenic microarchitecture in early lymphocytic choriomeningitis virus production.

scientific article

Role of different T cell receptors in the development of pre-T cells.

scientific article

Roles for NK cells and an NK cell-independent source of intestinal gamma interferon for innate immunity to Cryptosporidium parvum infection

scientific article published on 17 August 2009

Roles of lymphoid cells in the differentiation of Langerhans dendritic cells in mice

scientific article published on 01 January 2004

Slowing down differentiation of engrafted human myoblasts into immunodeficient mice correlates with increased proliferation and migration

scientific article published on 20 September 2011

Small bowel enteropathy: role of intraepithelial lymphocytes and of cytokines (IL-12, IFN-gamma, TNF) in the induction of epithelial cell death and renewal

scientific article published in February 1998

Staying innate: transcription factor maintenance of innate lymphoid cell identity.

scientific article

Stress-induced ClpP serine protease of Listeria monocytogenes is essential for induction of listeriolysin O-dependent protective immunity.

scientific article

Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation.

scientific article published on March 2017

T-cell development in the absence of the pre-T-cell receptor

article

Taming the beast within: regulation of innate lymphoid cell homeostasis and function.

scientific article

Targeted gene correction of α1-antitrypsin deficiency in induced pluripotent stem cells

scientific article

Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity

scientific article published on 20 January 2010

The Citrobacter rodentium type III secretion system effector EspO affects mucosal damage repair and antimicrobial responses

scientific article published on 26 October 2018

The Natural Cytotoxicity Receptor NKp46 Is Dispensable for IL-22-Mediated Innate Intestinal Immune Defense against Citrobacter rodentium

scientific article published on 21 October 2009

The Rag2⁻Il2rb⁻Dmd⁻ mouse: a novel dystrophic and immunodeficient model to assess innovating therapeutic strategies for muscular dystrophies

scientific article published on 23 August 2013

The Spectrum and Regulatory Landscape of Intestinal Innate Lymphoid Cells Are Shaped by the Microbiome

scientific article

The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling.

scientific article

The innate side of TOX

scientific article published on 01 October 2010

The intrathymic crossroads of T and NK cell differentiation ⬇️

scientific article published on November 1, 2010

The murine interleukin-2 receptor gamma chain gene: organization, chromosomal localization and expression in the adult thymus.

scientific article published in December 1994

The p56lck SH2 domain mediates recruitment of CD8/p56lck to the activated T cell receptor/CD3/zeta complex.

scientific article published on September 1996

The thymus exports long-lived fully committed T cell precursors that can colonize primary lymphoid organs

article

Thymic dependence of invariant Vα14+ Natural Killer-T cell development

article

Thymic epithelial cells: the multi-tasking framework of the T cell "cradle".

scientific article published on 24 September 2009

Thymic stromal-derived lymphopoietin distinguishes fetal from adult B cell development

article

Thymocyte selection regulates the homeostasis of IL-7-expressing thymic cortical epithelial cells in vivo.

scientific article published on 21 June 2013

Thymocytes may persist and differentiate without any input from bone marrow progenitors ⬇️

scientific article published on July 9, 2012

To be or not to be a pro-T?

scientific article

Trained ILC3 responses promote intestinal defense

scientific article published in 2022

Transcriptional diversity at the duplicated human CD8 beta loci

scientific article published in February 1993

Transcriptional regulation of innate lymphoid cell fate.

scientific article published on 12 June 2015

Tyr394 and Tyr505 are autophosphorylated in recombinant Lck protein-tyrosine kinase expressed in Escherichia coli.

scientific article

Tyrosine kinase SYK: essential functions for immunoreceptor signalling

scientific article (publication date: March 2000)

Ultrastructural Studies of Implantation Sites from Mice Deficient in Uterine Natural Killer Cells

scientific article published on 01 September 2000

Uncoupling protein-3 (UCP3) mRNA expression in reconstituted human muscle after myoblast transplantation in RAG2-/-/gamma c/C5(-) immunodeficient mice

scientific article published on 25 September 2002

c-Jun NH2-terminal kinase/c-Jun signaling promotes survival and metastasis of B lymphocytes transformed by Theileria

scientific article published in June 2006

γc cytokines provide multiple homeostatic signals to naive CD4+ T cells

scientific article published on 01 September 2007

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