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List of works by Shohei Koyama

Activation of the PD-1 pathway contributes to immune escape in EGFR-driven lung tumors

scientific article published on 27 September 2013

Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints.

scientific article

Apoptosis-derived membrane vesicles drive the cGAS-STING pathway and enhance type I IFN production in systemic lupus erythematosus

scientific article published on 26 June 2018

Author Correction: Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors

scientific article published on 01 March 2019

Clarifying the biological significance of the CHK2 K373E somatic mutation discovered in The Cancer Genome Atlas database

scientific article published on 7 October 2016

Combined small cell lung carcinoma harboring ALK rearrangement: A case report and literature review

scientific article published on 25 October 2020

Compartment-Specific Bioluminescence Imaging platform for the high-throughput evaluation of antitumor immune function

scientific article

Cutting Edge: TLR-Dependent viral recognition along with type I IFN positive feedback signaling masks the requirement of viral replication for IFN-{alpha} production in plasmacytoid dendritic cells

scientific article published in April 2009

Cytotoxic T Cells in PD-L1-Positive Malignant Pleural Mesotheliomas Are Counterbalanced by Distinct Immunosuppressive Factors

scientific article published on 14 November 2016

Development of Selective Covalent Janus Kinase 3 Inhibitors.

scientific article published on 10 August 2015

Double deletion of tetraspanins CD9 and CD81 in mice leads to a syndrome resembling accelerated aging.

scientific article published on 23 March 2018

Host innate immune receptors and beyond: making sense of microbial infections

scientific article

Immune surveillance and therapy of lymphomas driven by Epstein-Barr virus protein LMP1 in a mouse model

scientific article published on February 2012

Immunogenicity of whole-parasite vaccines against Plasmodium falciparum involves malarial hemozoin and host TLR9.

scientific article published in January 2010

Immunophenotyping of pediatric brain tumors: correlating immune infiltrate with histology, mutational load, and survival and assessing clonal T cell response.

scientific article

Innate and adaptive immune responses to viral infection and vaccination

scientific article published on 30 July 2011

Innate immune control of nucleic acid-based vaccine immunogenicity

scientific article published on August 2009

Innate immune response to viral infection

scientific article published on 09 August 2008

Interleukin-17A Promotes Lung Tumor Progression through Neutrophil Attraction to Tumor Sites and Mediating Resistance to PD-1 Blockade

scientific article published on 5 May 2017

Intranasal immunization with a mixture of PspA and a Toll-like receptor agonist induces specific antibodies and enhances bacterial clearance in the airways of mice

scientific article published on 8 April 2009

Intranasal vaccination with pneumococcal surface protein A plus poly(I:C) protects against secondary pneumococcal pneumonia in mice

article by Hirokazu Ezoe et al published February 2011 in Vaccine

Lamtor1 Is Critically Required for CD4(+) T Cell Proliferation and Regulatory T Cell Suppressive Function.

scientific article

Lkb1 inactivation drives lung cancer lineage switching governed by Polycomb Repressive Complex 2.

scientific article published on 7 April 2017

Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression

scientific article

Lysosomal Protein Lamtor1 Controls Innate Immune Responses via Nuclear Translocation of Transcription Factor EB.

scientific article published on 23 April 2018

Monitoring antibody binding to T cells in a pembrolizumab-treated patient with lung adenocarcinoma on hemodialysis

scientific article published on 14 September 2019

Mycobacterial hypersensitivity pneumonitis requires TLR9-MyD88 in lung CD11b+ CD11c+ cells

scientific article published on 27 January 2011

N-terminal deletion augments the cell-death-inducing activity of BAX in adenoviral gene delivery to nonsmall cell lung cancers

scientific article published in May 2003

Nonagonistic Dectin-1 ligand transforms CpG into a multitask nanoparticulate TLR9 agonist

scientific article

Plasmacytoid dendritic cells delineate immunogenicity of influenza vaccine subtypes

scientific article published in March 2010

STK11/LKB1 Deficiency Promotes Neutrophil Recruitment and Proinflammatory Cytokine Production to Suppress T-cell Activity in the Lung Tumor Microenvironment.

scientific article published on February 2016

Selecting suitable chemotherapies for PD-1/PD-L1 blockade to optimize the tumor immune microenvironment

scientific article published on 24 August 2018

Semaphorin 4D inhibits neutrophil activation and is involved in the pathogenesis of neutrophil-mediated autoimmune vasculitis.

scientific article

Semaphorin 6D reverse signaling controls macrophage lipid metabolism and anti-inflammatory polarization.

scientific article

Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors

scientific article published on 13 August 2018

Successful continuous nivolumab therapy for metastatic non-small cell lung cancer after local treatment of oligometastatic lesions

scientific article published on 21 June 2020

TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines

scientific article published in Nature

The role of multiple toll-like receptor signalling cascades on interactions between biomedical polymers and dendritic cells

scientific article published on 08 May 2010

Trastuzumab emtansine suppresses the growth of HER2-positive small-cell lung cancer in preclinical models

scientific article published on 16 May 2017

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