List of works - Leslie M. Loew

A fluorometric approach to local electric field measurements in a voltage-gated ion channel

scientific article published in January 2003

A minimal actomyosin-based model predicts the dynamics of filopodia on neuronal dendrites

scientific article

A naphthyl analog of the aminostyryl pyridinium class of potentiometric membrane dyes shows consistent sensitivity in a variety of tissue, cell, and model membrane preparations

scientific article

A wave of IP3 production accompanies the fertilization Ca2+ wave in the egg of the frog, Xenopus laevis: theoretical and experimental support

scientific article published in May 2004

Absolute spectroscopic determination of cross-membrane potential

scientific article published on 01 December 1993

Achievements and Challenges for Our Society's Journal.

scientific article published in June 2017

Action potential propagation in transverse-axial tubular system is impaired in heart failure.

scientific article

Actomyosin Dynamics Determine the Extension and Retraction of Filopodia on Neuronal Dendrites

Amino(oligo)thiophene-based environmentally sensitive biomembrane chromophores

scientific article published on 30 July 2008

An open model of actin dendritic nucleation

scientific article published on May 2009

Analysis of nonlinear dynamics on arbitrary geometries with the Virtual Cell.

scientific article

Analysis of phosphatidylinositol-4,5-bisphosphate signaling in cerebellar Purkinje spines

scientific article

Anatomic localization and autonomic modulation of atrioventricular junctional rhythm in failing human hearts

scientific article

Author Appreciation

scientific article published in August 2015

Biophysical Journal 60 Years after Hodgkin-Huxley

scientific article published in July 2012

Biophysical journal and the biophysics community

scientific article published on May 2014

Cardiac electrophysiological imaging systems scalable for high-throughput drug testing

scientific article

Characterization and application of a new optical probe for membrane lipid domains

scientific article

Characterization of a new series of fluorescent probes for imaging membrane order

scientific article

Characterization of voltage-sensitive dyes in living cells using two-photon excitation

scientific article published in January 2013

Cholesterol-enriched lipid domains can be visualized by di-4-ANEPPDHQ with linear and nonlinear optics

scientific article

Combined optogenetics and voltage sensitive dye imaging at single cell resolution

scientific article

Compartmental and Spatial Rule-Based Modeling with Virtual Cell

scientific article

Computational analysis of Rho GTPase cycling

scientific article (publication date: 2013)

Computational analysis of calcium signaling and membrane electrophysiology in cerebellar Purkinje neurons associated with ataxia

scientific article

Computational cell biologists snowed in at Cranwell.

scientific article published in June 2001

Computational cell biology: spatiotemporal simulation of cellular events

scientific article

Computational neurobiology is a useful tool in translational neurology: the example of ataxia

scientific article

Construction of a fluorescent biosensor family

scientific article published on November 2002

Correction: Stoichiometry of Nck-dependent actin polymerization in living cells

scientific article published in December 2015

Cortically restricted production of IP3 leads to propagation of the fertilization Ca2+ wave along the cell surface in a model of the Xenopus egg.

scientific article published in December 2004

Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure

scientific article

Design and Use of Organic Voltage Sensitive Dyes

scientific article published on January 2015

Distinct electric potentials in soma and neurite membranes

scientific article published on 01 November 1994

Dye screening and signal-to-noise ratio for retrogradely transported voltage-sensitive dyes

article

Dynamics of action potential backpropagation in basal dendrites of prefrontal cortical pyramidal neurons

scientific article

EPSPs Measured in Proximal Dendritic Spines of Cortical Pyramidal Neurons.

scientific article published on March 2016

Electric field-directed fibroblast locomotion involves cell surface molecular reorganization and is calcium independent.

scientific article published on October 1994

Endogenous inhibitors of InsP3-induced Ca2+ release in neuroblastoma cells

scientific article published in September 2005

Evaluation of voltage-sensitive fluorescence dyes for monitoring neuronal activity in the embryonic central nervous system

scientific article

Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability.

scientific article

Geometry Shapes Cell Signaling Network Output

scientific article published on 01 June 2008

High-precision recording of the action potential in isolated cardiomyocytes using the near-infrared fluorescent dye di-4-ANBDQBS.

scientific article

Imaging activity of neuronal populations with new long-wavelength voltage-sensitive dyes

scientific article published on December 2008

In situ optical mapping of voltage and calcium in the heart

scientific article (publication date: 2012)

In vivo ratiometric optical mapping enables high-resolution cardiac electrophysiology in pig models

scientific article published on 01 September 2019

Initiation of sodium spikelets in basal dendrites of neocortical pyramidal neurons.

scientific article published on November 2005

Integration of linear and dendritic actin nucleation in Nck-induced actin comets

scientific article

Integration of modeling with experimental and clinical findings synthesizes and refines the central role of inositol 1,4,5-trisphosphate receptor 1 in spinocerebellar ataxia

scientific article

Intracellular long-wavelength voltage-sensitive dyes for studying the dynamics of action potentials in axons and thin dendrites

scientific article

Intracellular signaling: spatial and temporal control

scientific article

Isolation, characterization and partial purification of a transferable membrane channel (amoebapore) produced by Entamoeba histolytica

scientific article published on 01 March 1989

Kinetic analysis of receptor-activated phosphoinositide turnover

scientific article

Lipid composition affects the rate of photosensitized dissipation of cross-membrane diffusion potential on liposomes

scientific article

Listening to membrane potential: photoacoustic voltage-sensitive dye recording

scientific article published in April 2017

Local photorelease of caged thymosin beta4 in locomoting keratocytes causes cell turning

scientific article

Low-Cost Optical Mapping Systems for Panoramic Imaging of Complex Arrhythmias and Drug-Action in Translational Heart Models

scientific article

Modeling and analysis of calcium signaling events leading to long-term depression in cerebellar Purkinje cells.

scientific article

Modeling capping protein FRAP and CALI experiments reveals in vivo regulation of actin dynamics

scientific article

MolClustPy: a Python package to characterize multivalent biomolecular clusters

scientific article published in 2023

Molecular machines or pleiomorphic ensembles: signaling complexes revisited

scientific article published on 16 October 2009

Monitoring membrane potential with second-harmonic generation

scientific article

Near-infrared voltage-sensitive fluorescent dyes optimized for optical mapping in blood-perfused myocardium

scientific article

New and Notable Changes at Biophysical Journal

scientific article

New near-infrared optical probes of cardiac electrical activity

scientific article published on 6 January 2006

Nonlinear optical potentiometric dyes optimized for imaging with 1064-nm light

scientific article

Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy.

scientific article published on 20 December 2015

Novel naphthylstyryl-pyridium potentiometric dyes offer advantages for neural network analysis

scientific article published in April 2004

OLM interneurons differentially modulate CA3 and entorhinal inputs to hippocampal CA1 neurons

scientific article

Optical mapping of the isolated coronary-perfused human sinus node

scientific article published on October 2010

Palette of fluorinated voltage-sensitive hemicyanine dyes

scientific article

Pathway Commons at virtual cell: use of pathway data for mathematical modeling

scientific article

Perspectives on Sharing Models and Related Resources in Computational Biomechanics Research

scientific article

Physiological cytosolic Ca2+ transients evoke concurrent mitochondrial depolarizations.

scientific article

Pleomorphic ensembles: formation of large clusters composed of weakly interacting multivalent molecules

scientific article published on December 2013

Probing the function of neuronal populations: combining micromirror-based optogenetic photostimulation with voltage-sensitive dye imaging

scientific article published on 17 December 2012

Probing the spatiotemporal relationship between intracellular Ca2+release and action potential propagation in cardiomyocytes by ultrafast multi-photon random access microscopy

Proteo-lipobeads for the oriented encapsulation of membrane proteins

scientific article published on April 2015

Quantitative cell biology with the Virtual Cell

scientific article published on November 2003

Real-time optical manipulation of cardiac conduction in intact hearts

scientific article published on 07 August 2018

Recording membrane potential changes through photoacoustic voltage sensitive dye

Reproducibility of research in biophysics

scientific article published on April 2015

STAT module can function as a biphasic amplitude filter.

scientific article published in March 2005

Science communication: Quality at stake

scientific article

Second Harmonic Imaging of Membrane Potential

scientific article published on January 2015

Second harmonic imaging of exocytosis at fertilization

scientific article

Second-harmonic imaging microscopy for visualizing biomolecular arrays in cells, tissues and organisms

scientific article

Simultaneous measurement and modulation of multiple physiological parameters in the isolated heart using optical techniques

scientific article

Simultaneous recording of t-tubular electrical activity and Ca2+-release in heart failure

Single-sensor system for spatially resolved, continuous, and multiparametric optical mapping of cardiac tissue

scientific article published in April 2011

Single-voxel recording of voltage transients in dendritic spines

scientific article

Spatial modeling of cell signaling networks

scientific article

SpringSaLaD: A Spatial, Particle-Based Biochemical Simulation Platform with Excluded Volume

scientific article published on February 2016

Stoichiometry of Nck-dependent actin polymerization in living cells

scientific article published on 21 May 2012

Superresolving dendritic spines

scientific article published on February 2013

Synthesis, spectra, delivery and potentiometric responses of new styryl dyes with extended spectral ranges

scientific article

Systems analysis of Ran transport

scientific article

Technical features of a CCD video camera system to record cardiac fluorescence data ⬇️

scientific article published on July 1, 1997

Ten steps to investigate a cellular system with mathematical modeling

scientific article published in 2021

The systems biology markup language (SBML): a medium for representation and exchange of biochemical network models

scientific article (publication date: March 2003)

There is more than one way to model an elephant. Experiment-driven modeling of the actin cytoskeleton

scientific article

Think Simulation - Think Experiment: The Virtual Cell Paradigm

Topology of the mitochondrial inner membrane: dynamics and bioenergetic implications.

scientific article

Transcranial in vivo recording of neural activity in the rodent brain with near-infrared photoacoustic voltage-sensitive dye imaging

Transcranial photoacoustic imaging of NMDA-evoked focal circuit dynamics in rat hippocampus

scientific article published on 21 February 2020

Unique contrast patterns from resonance-enhanced chiral SHG of cell membranes

scientific article published on August 2006

Unraveling Genome Biophysics

scientific article published on 18 January 2017

Use of virtual cell in studies of cellular dynamics

scientific article

Virtual Cell modelling and simulation software environment.

scientific article

Virtual NEURON: a strategy for merged biochemical and electrophysiological modeling

scientific article published on 22 February 2011

Voltage-sensitive dyes for monitoring multineuronal activity in the intact central nervous system

scientific article

Where does all the PIP2 come from?

scientific article published on 29 March 2007

[3] Second harmonic imaging microscopy

article

mol2sphere: Spherical Decomposition of Multi-Domain Molecules for Visualization and Coarse Grained Spatial Modeling

scientific article published on 01 November 2018

pH and Potential Transients of the bc1 Complex Co-Reconstituted in Proteo-Lipobeads with the Reaction Center from Rb. sphaeroides.

scientific article

List of works by Leslie M. Loew

A fluorometric approach to local electric field measurements in a voltage-gated ion channel

A minimal actomyosin-based model predicts the dynamics of filopodia on neuronal dendrites

A naphthyl analog of the aminostyryl pyridinium class of potentiometric membrane dyes shows consistent sensitivity in a variety of tissue, cell, and model membrane preparations

A wave of IP3 production accompanies the fertilization Ca2+ wave in the egg of the frog, Xenopus laevis: theoretical and experimental support

Absolute spectroscopic determination of cross-membrane potential

Achievements and Challenges for Our Society's Journal.

Action potential propagation in transverse-axial tubular system is impaired in heart failure.

Actomyosin Dynamics Determine the Extension and Retraction of Filopodia on Neuronal Dendrites

Amino(oligo)thiophene-based environmentally sensitive biomembrane chromophores

An open model of actin dendritic nucleation

Analysis of nonlinear dynamics on arbitrary geometries with the Virtual Cell.

Analysis of phosphatidylinositol-4,5-bisphosphate signaling in cerebellar Purkinje spines

Anatomic localization and autonomic modulation of atrioventricular junctional rhythm in failing human hearts

Author Appreciation

Biophysical Journal 60 Years after Hodgkin-Huxley

Biophysical journal and the biophysics community

Cardiac electrophysiological imaging systems scalable for high-throughput drug testing

Characterization and application of a new optical probe for membrane lipid domains

Characterization of a new series of fluorescent probes for imaging membrane order

Characterization of voltage-sensitive dyes in living cells using two-photon excitation

Cholesterol-enriched lipid domains can be visualized by di-4-ANEPPDHQ with linear and nonlinear optics

Combined optogenetics and voltage sensitive dye imaging at single cell resolution

Compartmental and Spatial Rule-Based Modeling with Virtual Cell

Computational analysis of Rho GTPase cycling

Computational analysis of calcium signaling and membrane electrophysiology in cerebellar Purkinje neurons associated with ataxia

Computational cell biologists snowed in at Cranwell.

Computational cell biology: spatiotemporal simulation of cellular events

Computational neurobiology is a useful tool in translational neurology: the example of ataxia

Construction of a fluorescent biosensor family

Correction: Stoichiometry of Nck-dependent actin polymerization in living cells

Cortically restricted production of IP3 leads to propagation of the fertilization Ca2+ wave along the cell surface in a model of the Xenopus egg.

Defects in T-tubular electrical activity underlie local alterations of calcium release in heart failure

Design and Use of Organic Voltage Sensitive Dyes

Distinct electric potentials in soma and neurite membranes

Dye screening and signal-to-noise ratio for retrogradely transported voltage-sensitive dyes

Dynamics of action potential backpropagation in basal dendrites of prefrontal cortical pyramidal neurons

EPSPs Measured in Proximal Dendritic Spines of Cortical Pyramidal Neurons.

Electric field-directed fibroblast locomotion involves cell surface molecular reorganization and is calcium independent.

Endogenous inhibitors of InsP3-induced Ca2+ release in neuroblastoma cells

Evaluation of voltage-sensitive fluorescence dyes for monitoring neuronal activity in the embryonic central nervous system

Fragility of foot process morphology in kidney podocytes arises from chaotic spatial propagation of cytoskeletal instability.

Geometry Shapes Cell Signaling Network Output

High-precision recording of the action potential in isolated cardiomyocytes using the near-infrared fluorescent dye di-4-ANBDQBS.

Imaging activity of neuronal populations with new long-wavelength voltage-sensitive dyes

In situ optical mapping of voltage and calcium in the heart

In vivo ratiometric optical mapping enables high-resolution cardiac electrophysiology in pig models

Initiation of sodium spikelets in basal dendrites of neocortical pyramidal neurons.

Integration of linear and dendritic actin nucleation in Nck-induced actin comets

Integration of modeling with experimental and clinical findings synthesizes and refines the central role of inositol 1,4,5-trisphosphate receptor 1 in spinocerebellar ataxia

Intracellular long-wavelength voltage-sensitive dyes for studying the dynamics of action potentials in axons and thin dendrites

Intracellular signaling: spatial and temporal control

Isolation, characterization and partial purification of a transferable membrane channel (amoebapore) produced by Entamoeba histolytica

Kinetic analysis of receptor-activated phosphoinositide turnover

Lipid composition affects the rate of photosensitized dissipation of cross-membrane diffusion potential on liposomes

Listening to membrane potential: photoacoustic voltage-sensitive dye recording

Local photorelease of caged thymosin beta4 in locomoting keratocytes causes cell turning

Low-Cost Optical Mapping Systems for Panoramic Imaging of Complex Arrhythmias and Drug-Action in Translational Heart Models

Modeling and analysis of calcium signaling events leading to long-term depression in cerebellar Purkinje cells.

Modeling capping protein FRAP and CALI experiments reveals in vivo regulation of actin dynamics

MolClustPy: a Python package to characterize multivalent biomolecular clusters

Molecular machines or pleiomorphic ensembles: signaling complexes revisited

Monitoring membrane potential with second-harmonic generation

Near-infrared voltage-sensitive fluorescent dyes optimized for optical mapping in blood-perfused myocardium

New and Notable Changes at Biophysical Journal

New near-infrared optical probes of cardiac electrical activity

Nonlinear optical potentiometric dyes optimized for imaging with 1064-nm light

Novel insights on the relationship between T-tubular defects and contractile dysfunction in a mouse model of hypertrophic cardiomyopathy.

Novel naphthylstyryl-pyridium potentiometric dyes offer advantages for neural network analysis

OLM interneurons differentially modulate CA3 and entorhinal inputs to hippocampal CA1 neurons

Optical mapping of the isolated coronary-perfused human sinus node

Palette of fluorinated voltage-sensitive hemicyanine dyes

Pathway Commons at virtual cell: use of pathway data for mathematical modeling

Perspectives on Sharing Models and Related Resources in Computational Biomechanics Research

Physiological cytosolic Ca2+ transients evoke concurrent mitochondrial depolarizations.

Pleomorphic ensembles: formation of large clusters composed of weakly interacting multivalent molecules

Probing the function of neuronal populations: combining micromirror-based optogenetic photostimulation with voltage-sensitive dye imaging

Probing the spatiotemporal relationship between intracellular Ca2+release and action potential propagation in cardiomyocytes by ultrafast multi-photon random access microscopy

Proteo-lipobeads for the oriented encapsulation of membrane proteins

Quantitative cell biology with the Virtual Cell