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List of works by Paul H. Weinreb

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The antibody aducanumab reduces Aβ plaques in Alzheimer’s disease

scientific article (publication date: 31 August 2016)
Identification of a Mycobacterium tuberculosis gene cluster encoding the biosynthetic enzymes for assembly of the virulence-conferring siderophore mycobactin

scientific journal article
Characterization of Sfp, a Bacillus subtilis phosphopantetheinyl transferase for peptidyl carrier protein domains in peptide synthetases

scientific article published on 01 February 1998
Partial inhibition of integrin alpha(v)beta6 prevents pulmonary fibrosis without exacerbating inflammation

scientific article published on 04 October 2007
Post-translational modification of polyketide and nonribosomal peptide synthases

scientific article published on October 1, 1997
Inhibition of integrin alpha(v)beta6, an activator of latent transforming growth factor-beta, prevents radiation-induced lung fibrosis

scientific article
The core Alzheimer's peptide NAC forms amyloid fibrils which seed and are seeded by beta-amyloid: is NAC a common trigger or target in neurodegenerative disease?

scientific article published on 01 March 1995
HS1-Associated Protein X-1 Regulates Carcinoma Cell Migration and Invasion via Clathrin-Mediated Endocytosis of Integrin αvβ6

article
Interleukin-1beta causes acute lung injury via alphavbeta5 and alphavbeta6 integrin-dependent mechanisms.

scientific article published on 14 February 2008
Stromal features are predictive of disease mortality in oral cancer patients

scientific article published on 05 January 2011
Alphav beta6 integrin regulates renal fibrosis and inflammation in Alport mouse.

scientific article published on January 2007
Function-blocking integrin alphavbeta6 monoclonal antibodies: distinct ligand-mimetic and nonligand-mimetic classes

scientific article published on 11 February 2004
Mice that lack activity of alphavbeta6- and alphavbeta8-integrins reproduce the abnormalities of Tgfb1- and Tgfb3-null mice

scientific article published on January 2009
Overexpression of the alpha v beta 6 integrin in cervical squamous cell carcinoma is a prognostic factor for decreased survival

scientific article published on 01 July 2007
Lysophosphatidic acid induces alphavbeta6 integrin-mediated TGF-beta activation via the LPA2 receptor and the small G protein G alpha(q).

scientific article published on 15 January 2009
Enhanced potency of human Sonic hedgehog by hydrophobic modification.

scientific article published on April 2001
Antibody-mediated blockade of integrin alpha v beta 6 inhibits tumor progression in vivo by a transforming growth factor-beta-regulated mechanism

scientific article published on 01 January 2008
The alpha(v)beta6 integrin receptor for Foot-and-mouth disease virus is expressed constitutively on the epithelial cells targeted in cattle.

scientific article published on October 2005
The coagulation system contributes to alphaVbeta6 integrin expression and liver fibrosis induced by cholestasis.

scientific article
Betel-derived alkaloid up-regulates keratinocyte alphavbeta6 integrin expression and promotes oral submucous fibrosis.

scientific article published on 25 October 2010
Therapeutic targeting of integrin αvβ6 in breast cancer

scientific article
Overexpression of fibroblast growth factor-10 during both inflammatory and fibrotic phases attenuates bleomycin-induced pulmonary fibrosis in mice.

scientific article published on 04 June 2009
Obtustatin: a potent selective inhibitor of alpha1beta1 integrin in vitro and angiogenesis in vivo

scientific article published on 01 May 2003
Blockade of Nogo receptor ligands promotes functional regeneration of sensory axons after dorsal root crush.

scientific article
Characterization of integrin beta6 and thrombospondin-1 double-null mice

scientific journal article
Fibronectin-guided migration of carcinoma collectives

scientific article published on 19 January 2017
Lysophosphatidic acid increases proximal tubule cell secretion of profibrotic cytokines PDGF-B and CTGF through LPA2- and Gαq-mediated Rho and αvβ6 integrin-dependent activation of TGF-β

scientific article
Development of tissue-engineered models of oral dysplasia and early invasive oral squamous cell carcinoma.

scientific article
Cyclooxygenase-2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion.

scientific article published on November 2006
Connective tissue growth factor and integrin αvβ6: a new pair of regulators critical for ductular reaction and biliary fibrosis in mice

scientific article
Integrin αvβ6 critically regulates hepatic progenitor cell function and promotes ductular reaction, fibrosis, and tumorigenesis.

scientific article published on 08 October 2015
αvβ6 integrin may be a potential prognostic biomarker in interstitial lung disease

scientific article
Characterization of trisulfide modification in antibodies

scientific article published on 18 January 2010
Influenza promotes collagen deposition via αvβ6 integrin-mediated transforming growth factor β activation

scientific article
Genetic deletion and pharmacological inhibition of Nogo-66 receptor impairs cognitive outcome after traumatic brain injury in mice.

scientific article
Immunotherapy with Aducanumab Restores Calcium Homeostasis in Tg2576 Mice.

scientific article
Type I collagen-targeted PET probe for pulmonary fibrosis detection and staging in preclinical models.

scientific article published in April 2017
Overexpression of the alphavbeta6 integrin in endometrial cancer

scientific article published on 01 December 2008
Effect of wound type on Smad 2 and 4 translocation

scientific article
Stoichiometry and Specificity of In Vitro Phosphopantetheinylation and Aminoacylation of the Valine-Activating Module of Surfactin Synthetase

scientific article published on February 10, 1998
Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis

scientific article published on 07 February 2014
Proteomic identification of lynchpin urokinase plasminogen activator receptor protein interactions associated with epithelial cancer malignancy.

scientific article published on March 2007
Crystal structure of the alpha1beta1 integrin I domain in complex with an antibody Fab fragment

scientific article (publication date: 11 April 2003)
Structural and kinetic basis for the selectivity of aducanumab for aggregated forms of amyloid-β.

scientific article published on 23 April 2018
Integrin alphavbeta6 and mediators of extracellular matrix deposition are up-regulated in experimental biliary atresia.

scientific article published on 20 June 2008
Dynamic structural changes are observed upon collagen and metal ion binding to the integrin α1 I domain.

scientific article
α(V)β(6) integrin expression is induced in the POET and Pten(pc-/-) mouse models of prostatic inflammation and prostatic adenocarcinoma.

scientific article
Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis

scientific article
Amplification of TGFβ Induced ITGB6 Gene Transcription May Promote Pulmonary Fibrosis

scientific article
High expression of integrin β6 in association with the Rho-Rac pathway identifies a poor prognostic subgroup within HER2 amplified breast cancers.

scientific article published on 17 May 2016

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