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List of works by Jeffrey C. Horowitz

"Scar-cinoma": viewing the fibrotic lung mesenchymal cell in the context of cancer biology.

scientific article published on 30 March 2016

Acellular Normal and Fibrotic Human Lung Matrices as a Culture System for In Vitro Investigation ⬇️

scientific article published on August 30, 2012

Activation of the pro-survival phosphatidylinositol 3-kinase/AKT pathway by transforming growth factor-beta1 in mesenchymal cells is mediated by p38 MAPK-dependent induction of an autocrine growth factor.

scientific article

Combinatorial activation of FAK and AKT by transforming growth factor-beta1 confers an anoikis-resistant phenotype to myofibroblasts

scientific article published on 17 November 2006

Constitutive activation of prosurvival signaling in alveolar mesenchymal cells isolated from patients with nonresolving acute respiratory distress syndrome

scientific article

Effects of the protein kinase inhibitor, imatinib mesylate, on epithelial/mesenchymal phenotypes: implications for treatment of fibrotic diseases.

scientific article published on 11 January 2007

Endobronchial biopsy of an intrapulmonary arterial mass

scientific article published in January 2013

Endothelin-1 and transforming growth factor-beta1 independently induce fibroblast resistance to apoptosis via AKT activation

scientific article published on 2 February 2009

Future directions in idiopathic pulmonary fibrosis research. An NHLBI workshop report

scientific article published on January 2014

Glutaminolysis Epigenetically Regulates Antiapoptotic Gene Expression in Idiopathic Pulmonary Fibrosis Fibroblasts

scientific article published on 01 January 2019

Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts.

scientific article published on 2 May 2013

Hydrogen peroxide is a diffusible paracrine signal for the induction of epithelial cell death by activated myofibroblasts

scientific article published on 16 February 2005

Implicating exudate macrophages and Ly-6C(high) monocytes in CCR2-dependent lung fibrosis following gene-targeted alveolar injury

scientific article published on 6 March 2013

Inhibition of myocardin-related transcription factor/serum response factor signaling decreases lung fibrosis and promotes mesenchymal cell apoptosis.

scientific article

Intestinal fibrosis is reduced by early elimination of inflammation in a mouse model of IBD: impact of a "Top-Down" approach to intestinal fibrosis in mice

scientific article published on 14 July 2011

Investigating Matrix-Fibroblast Regulation of MicroRNAs. A Dice(r)y Proposition

scientific article published on 01 August 2018

Matrix biology of idiopathic pulmonary fibrosis: a workshop report of the national heart, lung, and blood institute

scientific article

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis

scientific article

Mesenchymal cell fate and phenotypes in the pathogenesis of emphysema

scientific article

Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase.

scientific article published on 16 January 2003

NADPH oxidase-4 mediates myofibroblast activation and fibrogenic responses to lung injury.

scientific article published on 23 August 2009

PAI-1 promotes the accumulation of exudate macrophages and worsens pulmonary fibrosis following type II alveolar epithelial cell injury.

scientific article

Phlegmasia cerulea dolens: a rare cause of shock

scientific article published on 08 April 2019

Plakoglobin expression in fibroblasts and its role in idiopathic pulmonary fibrosis.

scientific article published on 6 November 2015

Plasminogen activation induced pericellular fibronectin proteolysis promotes fibroblast apoptosis

scientific article published on 26 July 2007

Prostaglandin E(2) induces fibroblast apoptosis by modulating multiple survival pathways.

scientific article

Prostaglandin E2's new trick: "decider" of differential alveolar cell life and death

scientific article published on July 2010

Pulmonary fibrosis induced by γ-herpesvirus in aged mice is associated with increased fibroblast responsiveness to transforming growth factor-β.

scientific article

Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli.

scientific article published on 10 May 2018

Releasing Tensin

scientific article published in April 2017

SMAD-independent down-regulation of caveolin-1 by TGF-β: effects on proliferation and survival of myofibroblasts

scientific article published on 6 February 2015

Smoking history, and not depression, is related to deficits in detection of happy and sad faces.

scientific article

Stress in the ER (endoplasmic reticulum): a matter of life and death for epithelial cells

scientific article published in October 2008

Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis ⬇️

scientific article published on October 25, 2011

TLR signaling prevents hyperoxia-induced lung injury by protecting the alveolar epithelium from oxidant-mediated death

scientific article

Targeting Inhibitor of Apoptosis Proteins Protects from Bleomycin-Induced Lung Fibrosis.

scientific article published on 17 September 2015

The vitronectin RGD motif regulates TGF-β-induced alveolar epithelial cell apoptosis.

scientific article

The vitronectin-binding function of PAI-1 exacerbates lung fibrosis in mice ⬇️

scientific article published on July 6, 2011

Ultrasound Strain Measurements for Evaluating Local Pulmonary Ventilation

scientific article published on 10 August 2016

Ultrasound Strain Measurements for Evaluating Local Pulmonary Ventilation.

scientific article

X-linked inhibitor of apoptosis regulates lung fibroblast resistance to Fas-mediated apoptosis.

scientific article published on July 2013

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