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Authors whose works are in public domain in at least one jurisdiction

List of works by Jurgen R. Haanstra

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Experimental and in silico analyses of glycolytic flux control in bloodstream form Trypanosoma brucei

scientific article published on 14 June 2005
Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia

scientific article published on 27 February 2012
Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

scholarly article
Control and regulation of gene expression: quantitative analysis of the expression of phosphoglycerate kinase in bloodstream form Trypanosoma brucei

scientific article published on 8 November 2007
Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels

scientific article
Lineage-instructive function of C/EBPα in multipotent hematopoietic cells and early thymic progenitors

scientific article published on 31 August 2010
EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs.

scientific article
Biogenesis, maintenance and dynamics of glycosomes in trypanosomatid parasites.

scientific article published on 15 September 2015
Differential regulation of agouti-related protein and neuropeptide Y in hypothalamic neurons following a stressful event.

scientific article
ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation

scientific article published on 16 March 2015
A domino effect in drug action: from metabolic assault towards parasite differentiation

scientific article published on 5 November 2010
Proliferating bloodstream-form Trypanosoma brucei use a negligible part of consumed glucose for anabolic processes

scientific article published on 08 May 2012
Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression

scientific article
Evolution, dynamics and specialized functions of glycosomes in metabolism and development of trypanosomatids

scientific article
Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism

scientific article
Targeting pathogen metabolism without collateral damage to the host

scientific article
Dissecting the catalytic mechanism of Trypanosoma brucei trypanothione synthetase by kinetic analysis and computational modeling

scientific article published on 28 June 2013
Network-based selectivity of antiparasitic inhibitors

scientific article published on 01 January 2002
The silicon trypanosome: a test case of iterative model extension in systems biology

scientific article published on January 2014
Loss of ercc1 results in a time- and dose-dependent reduction of proliferating early hematopoietic progenitors

scientific article
In or out? On the tightness of glycosomal compartmentalization of metabolites and enzymes in Trypanosoma brucei

scientific article published on December 2, 2014
Metabolite Depletion Affects Flux Profiling of Cell Lines

scientific article published on 12 April 2018
Drug target identification through systems biology

scientific article published on 17 July 2015
Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux

scientific article published on 3 April 2018
Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis

scientific article published on 27 April 2020

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