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List of works by Jurgen R. Haanstra

A domino effect in drug action: from metabolic assault towards parasite differentiation

scientific article published on 5 November 2010

Biogenesis, maintenance and dynamics of glycosomes in trypanosomatid parasites.

scientific article published on 15 September 2015

Compartmentation prevents a lethal turbo-explosion of glycolysis in trypanosomes

scholarly article

Control and regulation of gene expression: quantitative analysis of the expression of phosphoglycerate kinase in bloodstream form Trypanosoma brucei

scientific article published on 8 November 2007

Differential regulation of agouti-related protein and neuropeptide Y in hypothalamic neurons following a stressful event.

scientific article

Dissecting the catalytic mechanism of Trypanosoma brucei trypanothione synthetase by kinetic analysis and computational modeling

scientific article published on 28 June 2013

Drug target identification through systems biology

scientific article published on 17 July 2015

EVI1 is critical for the pathogenesis of a subset of MLL-AF9-rearranged AMLs.

scientific article

Evolution, dynamics and specialized functions of glycosomes in metabolism and development of trypanosomatids

scientific article

Experimental and in silico analyses of glycolytic flux control in bloodstream form Trypanosoma brucei

scientific article published on 14 June 2005

ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation.

scientific article published on 16 March 2015

In or out? On the tightness of glycosomal compartmentalization of metabolites and enzymes in Trypanosoma brucei.

scientific article

Integrative analysis of the Trypanosoma brucei gene expression cascade predicts differential regulation of mRNA processing and unusual control of ribosomal protein expression

scientific article

Lineage-instructive function of C/EBPα in multipotent hematopoietic cells and early thymic progenitors

scientific article published on 31 August 2010

Loss of ercc1 results in a time- and dose-dependent reduction of proliferating early hematopoietic progenitors

scientific article

Low affinity uniporter carrier proteins can increase net substrate uptake rate by reducing efflux

scientific article published on 3 April 2018

Metabolite Depletion Affects Flux Profiling of Cell Lines

scientific article published on 12 April 2018

Naphthoquinone derivatives exert their antitrypanosomal activity via a multi-target mechanism

scientific article

Network-based selectivity of antiparasitic inhibitors

scientific article published on 01 January 2002

Proliferating bloodstream-form Trypanosoma brucei use a negligible part of consumed glucose for anabolic processes

scientific article published on 08 May 2012

Quantitative analysis of amino acid metabolism in liver cancer links glutamate excretion to nucleotide synthesis

scientific article published on 27 April 2020

Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia

scientific article published on 27 February 2012

Targeting pathogen metabolism without collateral damage to the host

scientific article

The silicon trypanosome: a test case of iterative model extension in systems biology

scientific article published on January 2014

Transcriptome-wide analysis of trypanosome mRNA decay reveals complex degradation kinetics and suggests a role for co-transcriptional degradation in determining mRNA levels

scientific article

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