List of works by Kathelijn Fischer

A long-term prospective study of the natural course of sporadic adult-onset lower motor neuron syndromes.

scientific article published in June 2009

A modeling approach to evaluate long-term outcome of prophylactic and on demand treatment strategies for severe hemophilia A.

scientific article

Achieving self-management of prophylactic treatment in adolescents: The case of haemophilia

scientific article

Adherence to prophylaxis and bleeding in children: Significant drop during puberty but no correlation with bleeding

scientific article published on 01 June 2020

Adherence to prophylaxis and bleeding outcome in haemophilia: a multicentre study

scientific article

Age at first treatment and immune tolerance to factor VIII in severe hemophilia

scientific article published on 01 March 2003

Analysis of low frequency bleeding data: the association of joint bleeds according to baseline FVIII activity levels.

scientific article

Anticoagulation therapy in haemophilia. Managing the unknown

scientific article published on 28 February 2013

Antiviral therapy for chronic hepatitis C in patients with inherited bleeding disorders: an international, multicenter cohort study

scientific article published in August 2007

Assessing the test-retest reliability and smallest detectable change of the Haemophilia Activities List

scientific article published on 13 December 2020

Assessments of outcome in haemophilia - what is the added value of QoL tools?

scientific article published on 02 June 2015

Association between joint bleeds and Pettersson scores in severe haemophilia.

scientific article published in September 2002

Association of peak factor VIII levels and area under the curve with bleeding in patients with haemophilia A on every third day pharmacokinetic-guided prophylaxis

scientific article

BAY 94-9027, a PEGylated recombinant factor VIII, exhibits a prolonged half-life and higher area under the curve in patients with severe haemophilia A: Comprehensive pharmacokinetic assessment from clinical studies

scientific article published on 02 July 2018

Barrett's esophagus in children: does it need more attention?

scientific article published on 17 March 2011

Barriers and motivators of adherence to prophylactic treatment in haemophilia: a systematic review

scientific article published on 02 January 2013

Beneficial effect of successful HCV treatment in patients with inherited bleeding disorders, assessed by liver stiffness measurements

scientific article published on 21 November 2011

Beneficial vascular risk profile is associated with amyotrophic lateral sclerosis

scientific article published on 6 April 2011

Bleeding before prophylaxis in severe hemophilia: paradigm shift over two decades

scientific article published on 19 December 2014

Can long-term prophylaxis for severe haemophilia be stopped in adulthood? Results from Denmark and the Netherlands

scientific article

Can we consider discontinuing primary prophylaxis in adults with severe haemophilia?

scientific article

Challenges and key lessons from the design and implementation of an international haemophilia registry supported by a pharmaceutical company

scientific article published on 23 October 2020

Changes in treatment strategies for severe haemophilia over the last 3 decades: effects on clotting factor consumption and arthropathy

scientific article

Clinical severity of haemophilia A: does the classification of the 1950s still stand?

scientific article published on 5 May 2011

Comparative pharmacokinetics of plasma- and albumin-free recombinant factor VIII in children and adults: the influence of blood sampling schedule on observed age-related differences and implications for dose tailoring

scientific article

Comparing findings of routine Haemophilia Joint Health Score and Haemophlia Early Arthropathy Detection with UltraSound assessments in adults with haemophilia

scientific article published in March 2017

Comparing outcomes of different treatment regimens for severe haemophilia

scientific article published in May 2003

Comparing thrombin generation in patients with hemophilia A and patients on vitamin K antagonists

scientific article published on 15 March 2017

Continuous infusion of extended half-life factor VIII (efmoroctocog alpha) for surgery in severe haemophilia A

scientific article published on 25 July 2018

Coping in adult patients with severe haemophilia

scientific article published on 24 January 2014

Coping style and health-related quality of life in caregivers of epilepsy patients

scientific article

Coping style and quality of life in patients with epilepsy: a cross-sectional study

scientific article

Determinants of participation in patients with severe haemophilia

scientific article

Development and preliminary testing of a Paediatric Version of the Haemophilia Activities List (pedhal).

scientific article published on 11 November 2009

Diagnostic accuracy of point-of-care ultrasound for evaluation of early blood-induced joint changes: Comparison with MRI

scientific article published on 23 May 2018

Differentiating between signs of intra-articular joint bleeding and chronic arthropathy in haemophilia: a narrative review of the literature

scientific article published on 09 April 2015

Discontinuation of prophylactic therapy in severe haemophilia: incidence and effects on outcome.

scientific article

Discontinuing early prophylaxis in severe haemophilia leads to deterioration of joint status despite low bleeding rates

scientific article published on 21 January 2016

Do prothrombotic factors influence clinical phenotype of severe haemophilia? A review of the literature

scientific article published on 01 August 2004

Do the SIPPET study results apply to the patients I treat?

scientific article published on 8 December 2016

Dose and outcome of care in haemophilia--how do we define cost-effectiveness?

scientific article

Early endoscopic retrograde cholangiopancreatography in predicted severe acute biliary pancreatitis: a prospective multicenter study

scientific article

Effects of haemophilic arthropathy on health-related quality of life and socio-economic parameters

scientific article

Effects of prophylactic treatment regimens in children with severe haemophilia: a comparison of different strategies.

scientific article

Effects of vaginal prolapse surgery on sexuality in women and men; results from a RCT on repair with and without mesh

scientific article published on 9 February 2012

Efficacy and safety of rVIII-SingleChain: results of a phase 1/3 multicenter clinical trial in severe hemophilia A.

scientific article published on 21 June 2016

Efficacy assessment of a new clotting factor concentrate in haemophilia A patients, including prophylactic treatment

scientific article

Estimating and interpreting the pharmacokinetic profiles of individual patients with hemophilia A or B using a population pharmacokinetic approach: communication from the SSC of the ISTH.

scientific article published on 12 October 2017

Estimating unknown parameters in haemophilia using expert judgement elicitation

scientific article published on 15 May 2013

Evaluating international Haemophilia Joint Health Score (HJHS) results combined with expert opinion: Options for a shorter HJHS

scientific article published on 15 October 2020

Evaluating outcome of prophylaxis in haemophilia: objective and self-reported instruments should be combined

scientific article published on 8 February 2016

Evidence for and cost-effectiveness of physiotherapy in haemophilia: a Dutch perspective

scientific article published on 6 September 2016

Exposure to chemicals and metals and risk of amyotrophic lateral sclerosis: a systematic review

scientific article published on October 2009

Extremes in vitamin K status of bone are related to bone ultrasound properties in children with juvenile idiopathic arthritis

scientific article published in May 2008

FVIII inhibitor development according to concentrate: data from the EUHASS registry excluding overlap with other studies

scientific article

Functional limitations in Romanian children with haemophilia: further testing of psychometric properties of the Paediatric Haemophilia Activities List

scientific article

Habitual physical activity in Dutch children and adolescents with haemophilia

scientific article published on 4 May 2011

Haemophilia Joint Health Score in healthy adults playing sports

scientific article published on 24 October 2013

Haemophilic magnetic resonance imaging score in healthy controls playing sports

scientific article

Health-related quality of life as outcome parameter in haemophilia treatment.

scientific article

Health-related quality of life. The effect of pelvic floor muscle training and midurethral sling surgery: a systematic review

scientific article published on 22 March 2012

Hepatitis C and health-related quality of life among patients with hemophilia.

scientific article published in June 2005

Hepatitis C infection among Dutch haemophilia patients: a nationwide cross-sectional study of prevalence and antiviral treatment.

scientific article

Hepatitis C infection in children with haemophilia: a pilot study

scientific article published on November 2004

History of non-fatal cardiovascular disease in a cohort of Dutch and British patients with haemophilia

scientific article published on 3 August 2012

How to achieve full prophylaxis in young boys with severe haemophilia A: different regimens and their effect on early bleeding and venous access

scientific article published on 13 January 2015

Imaging of haemophilic arthropathy: Awareness of pitfalls and need for standardization

scientific article published on 21 June 2017

Impact of prophylaxis on health-related quality of life of boys with hemophilia: An analysis of pooled data from 9 countries

scientific article published on 23 April 2019

Improved prediction of inhibitor development in previously untreated patients with severe haemophilia A.

scientific article published on 11 December 2014

In-hospital rehabilitation after multiple joint procedures of the lower extremities in haemophilia patients: clinical guidelines for physical therapists

scientific article published on 04 April 2011

Including the life-time cumulative number of joint bleeds in the definition of primary prophylaxis

scientific article published on 01 May 2008

Increased prevalence of hypertension in haemophilia patients

scientific article published on 05 September 2012

Inhibitor development in haemophilia according to concentrate

scientific article published on 08 January 2015

Inhibitor development in non-severe haemophilia across Europe.

scientific article

Insufficient evidence to suggest less stringent therapy in hemophilia B?

scientific article published in November 2009

Intensity of factor VIII treatment and inhibitor development in children with severe hemophilia A: the RODIN study

scientific article published on 3 April 2013

Intermediate-dose versus high-dose prophylaxis for severe hemophilia: comparing outcome and costs since the 1970s

scientific article published on 18 June 2013

Intermittent cyclophosphamide with prednisone versus placebo for polyneuropathy with IgM monoclonal gammopathy.

scientific article published in July 2007

International cross-cultural validation study of the Canadian haemophilia outcomes: kids' life assessment tool

scientific article published on 4 December 2014

Interpreting data on inhibitor development from previously untreated patient studies, beware of premature conclusions

article

Intestinal Barrier Dysfunction in a Randomized Trial of a Specific Probiotic Composition in Acute Pancreatitis

article

Is joint effusion on MRI specific for haemophilia?

scientific article published on 23 December 2013

Joint health and functional ability in children with haemophilia who receive intensive replacement therapy

scientific article published on 25 July 2011

Large scale studies assessing anti-factor VIII antibody development in previously untreated haemophilia A: what has been learned, what to believe and how to learn more

scientific article

Laser-assisted endoscopic third ventriculostomy: long-term results in a series of 202 patients

scientific article

Learning intravenous infusion in haemophilia: experience from the Netherlands

scientific article published in February 2012

Lifetime occupation, education, smoking, and risk of ALS.

scientific article published in October 2007

Limits of agreement between raters are required for the use of HJHS 2.1 in clinical studies

scientific article published on 4 December 2014

Liver stiffness measurements to assess progression of fibrosis in HCV-infected patients with inherited bleeding disorders

scientific article published on 27 April 2011

Long-term effects of joint bleeding before starting prophylaxis in severe haemophilia

scientific article published on 11 July 2016

Long-term follow-up of hepatitis C infection in a large cohort of patients with inherited bleeding disorders

scientific article

Long-term impact of joint bleeds in von Willebrand disease: a nested case-control study

scientific article published on June 2017

Long-term outcome of individualized prophylactic treatment of children with severe haemophilia

scientific article published in March 2001

Long-term outcome of multiple joint procedures in haemophilia

scientific article published on 28 October 2013

Long-term safety and efficacy of extended-interval prophylaxis with recombinant factor IX Fc fusion protein (rFIXFc) in subjects with haemophilia B.

scientific article published on 22 December 2016

Long-term safety and sustained efficacy for up to 5 years of treatment with recombinant factor IX Fc fusion protein in subjects with haemophilia B: Results from the B-YOND extension study

scientific article published on 04 June 2020

MRI predicts 5-year joint bleeding and development of arthropathy on radiographs in hemophilia

scientific article published on 01 January 2020

Magnetic resonance imaging in teenagers and young adults with limited haemophilic arthropathy: baseline results from a prospective study

scientific article published on 24 March 2011

Models for prediction of factor VIII half-life in severe haemophiliacs: distinct approaches for blood group O and non-O patients

scientific article

Models of prophylaxis

scientific article published on July 2012

Monitoring joint health in haemophilia: Factors associated with deterioration.

scientific article published on 5 September 2017

Morbidity and mortality in ageing HIV-infected haemophilia patients

scientific article

Neonatal bleeding in haemophilia: a European cohort study

scientific article published on 7 December 2011

No protective effect of breastfeeding on inhibitor formation in severe hemophilia

scientific article

Non-fatal cardiovascular disease, malignancies, and other co-morbidity in adult haemophilia patients

scientific article published on 30 December 2011

Occurrence, course and risk factors of depression during antiviral treatment for chronic hepatitis C in patients with inherited bleeding disorders: a prospective study

scientific article

Outcome in moderate haemophilia

scientific article published on 20 November 2012

Outcome in pediatric hydrocephalus: a comparison between previously used outcome measures and the hydrocephalus outcome questionnaire

scientific article

PROTECT VIII Kids: BAY 94-9027 (PEGylated Recombinant Factor VIII) safety and efficacy in previously treated children with severe haemophilia A

scientific article published on 25 March 2020

Pain and functional limitations in patients with severe haemophilia

scientific article published in March 2006

Parental age and the risk of amyotrophic lateral sclerosis

scientific article published on 14 November 2012

Pathophysiological Mechanisms of Endogenous FVIII Release following Strenuous Exercise in Non-severe Haemophilia: A Review

scientific article published on 6 December 2017

Pegylated interferon and ribavirin combination therapy for chronic hepatitis C in patients with congenital bleeding disorders: a single-centre experience

scientific article published in January 2007

Phenotypic heterogeneity in severe hemophilia

scientific article published in July 2007

Platelet degranulation and glycoprotein IIbIIIa opening are not related to bleeding phenotype in severe haemophilia A patients

scientific article published on 30 January 2014

Population pharmacokinetics of recombinant factor VIII: the relationships of pharmacokinetics to age and body weight

scientific article published on 31 October 2011

Positioning extended half-life concentrates for future use: a practical proposal

scholarly article by Angelique Nederlof et al published September 2018 in Haemophilia

Practical considerations in choosing a factor VIII prophylaxis regimen: Role of clinical phenotype and trough levels

scientific article published on 21 January 2016

Predicting who will undergo surgery after physiotherapy for female stress urinary incontinence

scientific article published on 29 July 2014

Prediction of common bile duct stones in the earliest stages of acute biliary pancreatitis.

scientific article published on 22 October 2010

Primary prophylaxis in haemophilia care: Guideline update 2016

scientific article published on 18 March 2017

Primary prophylaxis in haemophilia care: Guideline update 2016.

scientific article published on 17 February 2017

Prognosis of polyneuropathy due to IgM monoclonal gammopathy: A prospective cohort study

scientific article published on 01 February 2010

Progression to end-stage liver disease in patients with inherited bleeding disorders and hepatitis C: an international, multicenter cohort study

scientific article published on 9 January 2007

Prophylactic treatment for severe haemophilia: comparison of an intermediate-dose to a high-dose regimen.

scientific article published in November 2002

Prophylactic versus on-demand treatment strategies for severe haemophilia: a comparison of costs and long-term outcome.

scientific article published in November 2002

Prophylaxis for adults with haemophilia: one size does not fit all.

scientific article published on April 2012

Prophylaxis for severe haemophilia: clinical and economical issues

scientific article published in July 2003

Prophylaxis for severe haemophilia: clinical challenges in the absence as well as in the presence of inhibitors

scientific article

Prophylaxis for severe hemophilia: experience from Europe and the United States

scientific article

Prophylaxis in real life scenarios

scientific article published on May 2014

Prospective observational cohort studies for studying rare diseases: the European PedNet Haemophilia Registry

scientific article

Protected by nature? Effects of strenuous physical exercise on FVIII activity in moderate and mild haemophilia A patients: a pilot study

scientific article

Purity of factor VIII product and incidence of inhibitors in previously untreated patients with haemophilia A.

scientific article

Quality of haemophilia care in The Netherlands: new standards for optimal care

scientific article

Quality of life of caregivers of patients with intractable epilepsy

scientific article published on 01 May 2009

RCTs and observational studies to determine the effect of prophylaxis in severe haemophilia

scientific article published in July 2007

Real-Life Pharmacokinetics of rFVIII-Fc and rFIX-Fc

scientific article published on 01 October 2020

Recombinant factor IX Fc fusion protein in children with haemophilia B (Kids B-LONG): results from a multicentre, non-randomised phase 3 study

scientific article published in February 2017

Reply to the letter of O'Mahoney et al.: Patient-reported outcome is not confined to HRQOL.

scientific article

Requirements for immune recognition and processing of factor VIII by antigen-presenting cells

scientific article published on 26 October 2011

Review of immune tolerance induction in hemophilia A.

scientific article published on 15 February 2018

Risk Factors for the Progression from Low to High Titres in 260 Children with Severe Haemophilia A and Newly Developed Inhibitors

scientific article published on 6 December 2017

Risk of inhibitor development in mild haemophilia A increases with age.

scientific article published on 19 August 2011

Risk stratification for inhibitor development at first treatment for severe hemophilia A: a tool for clinical practice

scientific article

Safety and efficacy of a plasma-derived monoclonal purified factor VIII concentrate during 10 years of follow-up

scientific article published on 18 September 2007

Scoring haemophilic arthropathy on X-rays: improving inter- and intra-observer reliability and agreement using a consensus atlas

scientific article published on 24 September 2015

Securing reimbursement for patient centered haemophilia care: major collaborative efforts are needed

scientific article published on March 2016

Significant liver damage in patients with bleeding disorders and chronic hepatitis C: non-invasive assessment of liver fibrosis using transient elastography

scientific article published on 01 January 2007

Smoking, Alcohol Consumption, and the Risk of Amyotrophic Lateral Sclerosis: A Population-based Study

scientific article published on 11 July 2012

Sports participation and physical activity in adult Dutch and Swedish patients with severe haemophilia: A comparison between intermediate- and high-dose prophylaxis

scientific article published on 28 January 2019

Sports participation and sports injuries in Dutch boys with haemophilia

scientific article published on 04 April 2020

Sports participation of patients with haemophilia in the COVID-19 era: The Dutch experience

scientific article published on 08 November 2020

Starreveld scoring method in diagnosing childhood constipation

scientific article

Successful low dose immune tolerance induction in severe haemophilia A with inhibitors below 40 Bethesda Units

scientific article published in May 2010

Surgery versus Physiotherapy for Stress Urinary Incontinence

Tailoring treatment of haemophilia B: accounting for the distribution and clearance of standard and extended half-life FIX concentrates.

scientific article published on 30 March 2017

Targeting factor replacement therapy in severe hemophilia: which level is important?

scientific article published on 09 October 2015

Terminal half-life of FVIII and FIX according to age, blood group and concentrate type: Data from the WAPPS database

scientific article published on 18 June 2021

The European Haemophilia Network (EUHANET)

scientific article

The European Principles of Haemophilia Care: a pilot investigation of adherence to the principles in Europe

scientific article published on 29 August 2012

The Paediatric Haemophilia Activities List (pedHAL) in routine assessment: changes over time, child-parent agreement and informative domains

scientific article published on 16 August 2019

The Perspectives of Adolescents and Young Adults on Adherence to Prophylaxis in Hemophilia: A Qualitative Study

scientific article published on 23 January 2020

The association of haemophilic arthropathy with Health-Related Quality of Life: a post hoc analysis

scientific article published on 26 October 2016

The burden of HCV treatment in patients with inherited bleeding disorders

scientific article published on 21 June 2011

The effects of postponing prophylactic treatment on long-term outcome in patients with severe hemophilia

scientific article

The natural history of childhood-acquired hepatitis C infection in patients with inherited bleeding disorders

scientific article published in August 2006

The small bowel pouch: technical and physiologic aspects of a new model of small intestinal grafting

scientific article published on 01 February 1989

The use of the Port-A-Cath in children with haemophilia--a review

scientific article published in July 1998

Timing of inhibitor development in more than 1000 previously untreated patients with severe hemophilia A

scientific article published on 11 June 2019

Treatment of chronic hepatitis C in patients with haemophilia: a review of the literature.

scientific article published on September 2006

Trends in bleeding patterns during prophylaxis for severe haemophilia: observations from a series of prospective clinical trials

scientific article published on 7 February 2011

Turning severe into moderate haemophilia by prophylaxis: are we reaching our goal?

scientific article

Unfavourable cardiovascular disease risk profiles in a cohort of Dutch and British haemophilia patients

scientific article published on 8 November 2012

Unravelling adherence to prophylaxis in haemophilia: a patients' perspective

scientific article published on 9 April 2015

Use of the CD19 count in a primary care laboratory as a screening method for B-cell chronic lymphoproliferative disorders in asymptomatic patients with lymphocytosis

scientific article published on 05 November 2010

Use of ultrasound for assessment of musculoskeletal disease in persons with haemophilia: Results of an International Prophylaxis Study Group global survey

scientific article published on 22 May 2020

Using routine Haemophilia Joint Health Score for international comparisons of haemophilia outcome: standardization is needed

scientific article

Using the Haemophilia Joint Health Score for assessment of teenagers and young adults: exploring reliability and validity

scientific article published on 4 June 2013

Validation of the prediction model for inhibitor development in PUPs with severe haemophilia A.

scientific article

Validity of assessing inhibitor development in haemophilia PUPs using registry data: the EUHASS project

scientific article

Value of routine ultrasound in detecting early joint changes in children with haemophilia using the 'Haemophilia Early Arthropathy Detection with UltraSound' protocol

scientific article

Variability in clinical phenotype of severe haemophilia: the role of the first joint bleed.

scientific article

What we truly know about occupation as a risk factor for ALS: A critical and systematic review

scientific article

When and how to start prophylaxis in boys with severe hemophilia without inhibitors: communication from the SSC of the ISTH.

scientific article

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