List of works - Isabelle Becher

A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles

scientific article published on 13 November 2020

Affinity profiling of the cellular kinome for the nucleotide cofactors ATP, ADP, and GTP.

scientific article published on 7 January 2013

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

scientific article

Chemoproteomics reveals time-dependent binding of histone deacetylase inhibitors to endogenous repressor complexes

scientific article published on 6 June 2014

Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition

scientific article

Functional interdependence of BRD4 and DOT1L in MLL leukemia

scientific article published on 13 June 2016

GSK6853, a Chemical Probe for Inhibition of the BRPF1 Bromodomain

scientific article published on 9 May 2016

H-score, a mass accuracy driven rescoring approach for improved peptide identification in modification rich samples

scientific article published on 21 September 2010

High-resolution enabled TMT 8-plexing.

scientific article

Identifying drug targets in tissues and whole blood with thermal-shift profiling

scientific article published on 20 January 2020

Ion mobility tandem mass spectrometry enhances performance of bottom-up proteomics

scientific article published on 8 August 2014

Measuring and managing ratio compression for accurate iTRAQ/TMT quantification

scientific article published on 2 July 2013

Meltome atlas-thermal proteome stability across the tree of life

scientific article published on 13 April 2020

Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis.

scientific article published on 3 March 2018

Pervasive Protein Thermal Stability Variation during the Cell Cycle.

scientific article published on 21 April 2018

Quantifying small molecule-induced changes in cellular protein expression and posttranslational modifications using isobaric mass tags

scientific article published on January 2014

Systematic analysis of protein turnover in primary cells.

scientific article published on 15 February 2018

Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat.

scientific article

List of works by Isabelle Becher

A computational method for detection of ligand-binding proteins from dose range thermal proteome profiles

Affinity profiling of the cellular kinome for the nucleotide cofactors ATP, ADP, and GTP.

Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes

Chemoproteomics reveals time-dependent binding of histone deacetylase inhibitors to endogenous repressor complexes

Discovery of I-BRD9, a Selective Cell Active Chemical Probe for Bromodomain Containing Protein 9 Inhibition

Functional interdependence of BRD4 and DOT1L in MLL leukemia

GSK6853, a Chemical Probe for Inhibition of the BRPF1 Bromodomain

H-score, a mass accuracy driven rescoring approach for improved peptide identification in modification rich samples

High-resolution enabled TMT 8-plexing.

Identifying drug targets in tissues and whole blood with thermal-shift profiling

Ion mobility tandem mass spectrometry enhances performance of bottom-up proteomics

Measuring and managing ratio compression for accurate iTRAQ/TMT quantification

Meltome atlas-thermal proteome stability across the tree of life

Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis.

Pervasive Protein Thermal Stability Variation during the Cell Cycle.

Quantifying small molecule-induced changes in cellular protein expression and posttranslational modifications using isobaric mass tags

Systematic analysis of protein turnover in primary cells.

Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat.