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List of works by Angelika Lampert

A pore-blocking hydrophobic motif at the cytoplasmic aperture of the closed-state Nav1.7 channel is disrupted by the erythromelalgia-associated F1449V mutation.

scientific article

Activating mutation of the renal epithelial chloride channel ClC-Kb, predisposing to hypertension

scientific article

Altered sodium channel gating as molecular basis for pain: contribution of activation, inactivation, and resurgent currents.

scientific article published on January 2014

Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na V 1.6-resurgent and persistent current ⬇️

scientific article published on April 9, 2012

Bisphenol A binds to the local anesthetic receptor site to block the human cardiac sodium channel

scientific article (publication date: 2012)

C-fiber recovery cycle supernormality depends on ion concentration and ion channel permeability.

scientific article

Chaperone-mediated native folding of a β-scorpion toxin in the periplasm of Escherichia coli

scientific article

Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling

scientific article

Conversion of Human Fibroblasts to Stably Self-Renewing Neural Stem Cells with a Single Zinc-Finger Transcription Factor.

scientific article published on 22 March 2016

DIsulfide Mapping PLanner Software Tool

scientific article

Dataset of electrophysiological patch-clamp recordings of the effect of the compounds deltamethrin, ATx-II and β4-peptide on human cardiac Nav1.5 sodium channel gating properties

scientific article published on 08 June 2020

Deranged Kv channel regulation in fibroblasts from mice lacking the serum and glucocorticoid inducible kinase SGK1.

scientific article published in July 2005

Differential axonal conduction patterns of mechano-sensitive and mechano-insensitive nociceptors--a combined experimental and modelling study.

scientific article

Differential roles of S6 domain hinges in the gating of KCNQ potassium channels.

scientific article

Effect of dexamethasone on voltage-gated K + channels in Jurkat T-lymphocytes

scientific article published on 02 August 2003

Erythromelalgia mutation L823R shifts activation and inactivation of threshold sodium channel Nav1.7 to hyperpolarized potentials.

scientific article published on October 2009

Erythromelalgia mutation Q875E Stabilizes the activated state of sodium channel Nav1.7.

scientific article published on 9 January 2015

Fibroblast growth factor homologous factor 2 (FGF-13) associates with Nav1.7 in DRG neurons and alters its current properties in an isoform-dependent manner

scientific article published on 27 March 2019

Functional expression of nicotinic acetylcholine receptors in rat neocortical layer 5 pyramidal cells

scientific article

GSK3ß-dependent dysregulation of neurodevelopment in SPG11-patient iPSC model

scientific article published on 11 March 2016

Gene dosage-dependent rescue of HSP neurite defects in SPG4 patients' neurons

scientific article published on 30 December 2013

Germs against pain: Humanized bacterial sodium channels

scientific article published on 24 June 2016

H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway

scientific article

Identification of aurintricarboxylic acid as a potent allosteric antagonist of P2X1 and P2X3 receptors

scientific article published on 25 August 2019

Influence of gain of function epithelial chloride channel ClC-Kb mutation on hearing thresholds

scientific article published on 23 March 2006

Inherited pain: sodium channel Nav1.7 A1632T mutation causes erythromelalgia due to a shift of fast inactivation.

scientific article published on 05 December 2013

Kinetic modeling of Nav1.7 provides insight into erythromelalgia-associated F1449V mutation

scientific article published on 2 February 2011

Markov modeling of ion channels: implications for understanding disease

scientific article published on January 2014

Modeling activity-dependent changes of axonal spike conduction in primary afferent C-nociceptors

scientific article published on 26 December 2013

Mutagenesis of the NaChBac sodium channel discloses a functional role for a conserved S6 asparagine.

scientific article published on 20 August 2017

Noncanonical Ion Channel Behaviour in Pain

scientific article published on 15 September 2019

Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors

Pattern of Functional TTX-Resistant Sodium Channels Reveals a Developmental Stage of Human iPSC- and ESC-Derived Nociceptors

scientific article published on 26 August 2015

Resurgent currents turn painfully exciting.

scientific article published on February 2011

Role of hippocampal sodium channel Nav1.6 in kindling epileptogenesis.

scientific article published on 14 July 2008

SCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing.

scientific article

Sensory renal innervation: a kidney-specific firing activity due to a unique expression pattern of voltage-gated sodium channels?

scientific article

Sodium channel slow inactivation interferes with open channel block

scientific article published on 13 May 2016

Sodium channelopathies and pain

scientific article published on 26 January 2010

Temperature dependence of erythromelalgia mutation L858F in sodium channel Nav1.7

scientific article

The distinct effects of lipid emulsions used for "lipid resuscitation" on gating and bupivacaine-induced inhibition of the cardiac sodium channel Nav1.5.

scientific article published in November 2013

The molecular basis for species-specific activation of human TRPA1 protein by protons involves poorly conserved residues within transmembrane domains 5 and 6.

scientific article published on 24 May 2013

The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5.

scientific article published on January 2014

The role of Nav1.7 in human nociceptors: insights from human induced pluripotent stem cell-derived sensory neurons of erythromelalgia patients

scientific article published on 01 June 2019

Thyrotropin serum concentrations in healthy volunteers are associated with depression-related personality traits.

scientific article published in January 2007

Translational Model Systems for Complex Sodium Channel Pathophysiology in Pain.

scientific article published on 28 January 2018

Upregulation of persistent and ramp sodium current in dorsal horn neurons after spinal cord injury.

scientific article published on 23 May 2006

β1 and β3 subunits amplify mechanosensitivity of the cardiac voltage-gated sodium channel Nav1.5.

scientific article published on 14 November 2019

β1 subunit stabilises sodium channel Nav1.7 against mechanical stress.

scientific article published on 16 April 2018

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