List of works - Charles Robert Flynn

A micro-RNA expression signature for human NAFLD progression

scientific article published on 13 February 2016

A novel cell permeant peptide inhibitor of MAPKAP kinase II inhibits intimal hyperplasia in a human saphenous vein organ culture model

scientific article

A post-developmental genetic screen for zebrafish models of inherited liver disease

scientific article published on 7 May 2015

Bile acids and bariatric surgery

scientific article published on 5 April 2017

Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery.

scientific article published on 21 July 2015

Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward

scientific article published on 26 July 2018

CD36 modulates fasting and preabsorptive hormone and bile acid levels.

scientific article published on 12 March 2018

Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-beta1-induced CTGF expression in keloid fibroblasts

scientific article published on 11 September 2008

Cell-permeant peptide inhibitors of vasospasm and intimal hyperplasia.

scientific article published on 26 October 2012

Characterization of the Human Adipocyte Proteome and Reproducibility of Protein Abundance by One-Dimensional Gel Electrophoresis and HPLC-ESI-MS/MS.

scientific article

Comparative study of the skin penetration of protein transduction domains and a conjugated peptide.

scientific article published on 17 May 2005

Comprehensive evaluation of extracellular small RNA isolation methods from serum in high throughput sequencing.

scientific article published on 07 January 2017

Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance.

scientific article

Differential intrahepatic phospholipid zonation in simple steatosis and nonalcoholic steatohepatitis

scientific article

Diverse Amino Acid Residues Function within the Type 1 Peroxisomal Targeting Signal (Implications for the Role of Accessory Residues Upstream of the Type 1 Peroxisomal Targeting Signal)

scientific article published on 01 November 1997

Early Increases in Bile Acids Post Roux-en-Y Gastric Bypass Are Driven by Insulin-Sensitizing, Secondary Bile Acids.

scientific article

Effects of proximal gut bypass on glucose tolerance and insulin sensitivity in humans.

scientific article published in April 2013

Global Assessment of Regulation of Phosphorylation of Insulin Receptor Substrate-1 by Insulin In Vivo in Human Muscle

scientific article published on 14 March 2007

Hepatic TLR4 signaling in obese NAFLD

scientific article

How are peroxisomes formed? The role of the endoplasmic reticulum and peroxins

scientific article

Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension.

scientific article

In vitro safety pharmacology evaluation of 2-hydroxybenzylamine acetate

scientific article published on 22 September 2018

In vivo phosphoproteome of human skeletal muscle revealed by phosphopeptide enrichment and HPLC-ESI-MS/MS.

scientific article published on November 2009

Inhibition of HSP27 phosphorylation by a cell-permeant MAPKAP Kinase 2 inhibitor

scientific article published on 14 March 2009

Internalization and intracellular trafficking of a PTD-conjugated anti-fibrotic peptide, AZX100, in human dermal keloid fibroblasts

scientific article published in July 2010

Intestinal Lymph Collection via Cannulation of the Mesenteric Lymphatic Duct in Mice

scientific article published on 28 November 2020

Limiting Injury During Saphenous Vein Graft Preparation For Coronary Arterial Bypass Prevents Metabolic Decompensation.

scientific article published on 27 October 2017

Lipoprotein Profiles in Class III Obese Caucasian and African American Women with Nonalcoholic Fatty Liver Disease.

scientific article published on 23 November 2015

Mapping of sudden infant death with dysgenesis of the testes syndrome (SIDDT) by a SNP genome scan and identification of TSPYL loss of function

scientific article

Metabolic Effects of Bile Acids: Potential Role in Bariatric Surgery

scientific article published on 07 May 2019

Mutational analyses of a type 2 peroxisomal targeting signal that is capable of directing oligomeric protein import into tobacco BY-2 glyoxysomes

article

Non-alcoholic fatty liver disease phosphoproteomics: A functional piece of the precision puzzle

scientific article

Phosphorylation and activation of a transducible recombinant form of human HSP20 in Escherichia coli

scientific article

Proteome profile of functional mitochondria from human skeletal muscle using one-dimensional gel electrophoresis and HPLC-ESI-MS/MS.

scientific article published on 28 June 2009

Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes

scientific article

Recent advances in metabolic and bariatric surgery

scientific article

Reduction in inflammatory gene expression in skeletal muscle from Roux-en-Y gastric bypass patients randomized to omentectomy

scientific article

Regulation of Insulin Receptor Pathway and Glucose Metabolism by CD36 Signaling.

scientific article

SIRT3 deacetylates ATP synthase F1 complex proteins in response to nutrient- and exercise-induced stress.

scientific article

Sialylated endogenous glycoconjugates in plant cells.

scientific article

Sirt3 Impairment and SOD2 Hyperacetylation in Vascular Oxidative Stress and Hypertension.

scientific article

Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

scientific article published on December 2010

Stable and transient expression of chimeric peroxisomal membrane proteins induces an independent "zippering" of peroxisomes and an endoplasmic reticulum subdomain

scientific article published in October 2001

Statistical strategies for microRNAseq batch effect reduction

scientific article

Supplemental safflower oil affects the fatty acid profile, including conjugated linoleic acid, of lamb

scientific article published in September 2005

The small heat shock-related protein, HSP20, is a cAMP-dependent protein kinase substrate that is involved in airway smooth muscle relaxation.

scientific article

Transducible recombinant small heat shock-related protein, HSP20, inhibits vasospasm and platelet aggregation

scientific article published in September 2004

Transduction of biologically active motifs of the small heat shock-related protein HSP20 leads to relaxation of vascular smooth muscle.

scientific article published on 8 May 2003

Transduction of phosphorylated heat shock-related protein 20, HSP20, prevents vasospasm of human umbilical artery smooth muscle.

scientific article

List of works by Charles Robert Flynn

A micro-RNA expression signature for human NAFLD progression

A novel cell permeant peptide inhibitor of MAPKAP kinase II inhibits intimal hyperplasia in a human saphenous vein organ culture model

A post-developmental genetic screen for zebrafish models of inherited liver disease

Bile acids and bariatric surgery

Bile diversion to the distal small intestine has comparable metabolic benefits to bariatric surgery.

Bile diversion, a bariatric surgery, and bile acid signaling reduce central cocaine reward

CD36 modulates fasting and preabsorptive hormone and bile acid levels.

Cell permeant peptide analogues of the small heat shock protein, HSP20, reduce TGF-beta1-induced CTGF expression in keloid fibroblasts

Cell-permeant peptide inhibitors of vasospasm and intimal hyperplasia.

Characterization of the Human Adipocyte Proteome and Reproducibility of Protein Abundance by One-Dimensional Gel Electrophoresis and HPLC-ESI-MS/MS.

Comparative study of the skin penetration of protein transduction domains and a conjugated peptide.

Comprehensive evaluation of extracellular small RNA isolation methods from serum in high throughput sequencing.

Connectivity map analysis of nonsense-mediated decay-positive BMPR2-related hereditary pulmonary arterial hypertension provides insights into disease penetrance.

Differential intrahepatic phospholipid zonation in simple steatosis and nonalcoholic steatohepatitis

Diverse Amino Acid Residues Function within the Type 1 Peroxisomal Targeting Signal (Implications for the Role of Accessory Residues Upstream of the Type 1 Peroxisomal Targeting Signal)

Early Increases in Bile Acids Post Roux-en-Y Gastric Bypass Are Driven by Insulin-Sensitizing, Secondary Bile Acids.

Effects of proximal gut bypass on glucose tolerance and insulin sensitivity in humans.

Global Assessment of Regulation of Phosphorylation of Insulin Receptor Substrate-1 by Insulin In Vivo in Human Muscle

Hepatic TLR4 signaling in obese NAFLD

How are peroxisomes formed? The role of the endoplasmic reticulum and peroxins

Hyperoxia synergizes with mutant bone morphogenic protein receptor 2 to cause metabolic stress, oxidant injury, and pulmonary hypertension.

In vitro safety pharmacology evaluation of 2-hydroxybenzylamine acetate

In vivo phosphoproteome of human skeletal muscle revealed by phosphopeptide enrichment and HPLC-ESI-MS/MS.

Inhibition of HSP27 phosphorylation by a cell-permeant MAPKAP Kinase 2 inhibitor

Internalization and intracellular trafficking of a PTD-conjugated anti-fibrotic peptide, AZX100, in human dermal keloid fibroblasts

Intestinal Lymph Collection via Cannulation of the Mesenteric Lymphatic Duct in Mice

Limiting Injury During Saphenous Vein Graft Preparation For Coronary Arterial Bypass Prevents Metabolic Decompensation.

Lipoprotein Profiles in Class III Obese Caucasian and African American Women with Nonalcoholic Fatty Liver Disease.

Mapping of sudden infant death with dysgenesis of the testes syndrome (SIDDT) by a SNP genome scan and identification of TSPYL loss of function

Metabolic Effects of Bile Acids: Potential Role in Bariatric Surgery

Mutational analyses of a type 2 peroxisomal targeting signal that is capable of directing oligomeric protein import into tobacco BY-2 glyoxysomes

Non-alcoholic fatty liver disease phosphoproteomics: A functional piece of the precision puzzle

Phosphorylation and activation of a transducible recombinant form of human HSP20 in Escherichia coli

Proteome profile of functional mitochondria from human skeletal muscle using one-dimensional gel electrophoresis and HPLC-ESI-MS/MS.

Proteomics analysis of human skeletal muscle reveals novel abnormalities in obesity and type 2 diabetes

Recent advances in metabolic and bariatric surgery

Reduction in inflammatory gene expression in skeletal muscle from Roux-en-Y gastric bypass patients randomized to omentectomy

Regulation of Insulin Receptor Pathway and Glucose Metabolism by CD36 Signaling.

SIRT3 deacetylates ATP synthase F1 complex proteins in response to nutrient- and exercise-induced stress.

Sialylated endogenous glycoconjugates in plant cells.

Sirt3 Impairment and SOD2 Hyperacetylation in Vascular Oxidative Stress and Hypertension.

Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.

Stable and transient expression of chimeric peroxisomal membrane proteins induces an independent "zippering" of peroxisomes and an endoplasmic reticulum subdomain

Statistical strategies for microRNAseq batch effect reduction

Supplemental safflower oil affects the fatty acid profile, including conjugated linoleic acid, of lamb

The small heat shock-related protein, HSP20, is a cAMP-dependent protein kinase substrate that is involved in airway smooth muscle relaxation.

Transducible recombinant small heat shock-related protein, HSP20, inhibits vasospasm and platelet aggregation

Transduction of biologically active motifs of the small heat shock-related protein HSP20 leads to relaxation of vascular smooth muscle.

Transduction of phosphorylated heat shock-related protein 20, HSP20, prevents vasospasm of human umbilical artery smooth muscle.