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List of works by Kevin S McIver

A PTS EII mutant library in Group A Streptococcus identifies a promiscuous man-family PTS transporter influencing SLS-mediated hemolysis.

scientific article

A model for using a concept inventory as a tool for students' assessment and faculty professional development.

scientific article

An extracellular bacterial pathogen modulates host metabolism to regulate its own sensing and proliferation

scientific article published on January 2014

CcpA-mediated repression of streptolysin S expression and virulence in the group A streptococcus.

scientific article published on 19 May 2008

Characterization of the Group A Streptococcus Mga virulence regulator reveals a role for the C-terminal region in oligomerization and transcriptional activation

scientific article published on March 2012

Complementation of divergent mga genes in group A Streptococcus

scientific article published in October 1996

Defining the Mga regulon: Comparative transcriptome analysis reveals both direct and indirect regulation by Mga in the group A streptococcus.

scientific article published on 08 September 2006

Discovery of glycerol phosphate modification on streptococcal rhamnose polysaccharides

scientific article published on 01 April 2019

Essential Genes in the Core Genome of the Human Pathogen Streptococcus pyogenes

scientific article

GacA is essential for Group A Streptococcus and defines a new class of monomeric dTDP-4-dehydrorhamnose reductases (RmlD)

scientific article published on 17 August 2015

Genetic manipulation of Streptococcus pyogenes (the Group A Streptococcus, GAS).

scientific article published on 02 October 2013

Genome-Wide Identification of Genes Required for Fitness of Group A Streptococcus in Human Blood ⬇️

scientific article published on January 7, 2013

Genome-wide discovery of novel M1T1 group A streptococcal determinants important for fitness and virulence during soft-tissue infection.

scientific article published on 23 August 2017

Global Analysis and Comparison of the Transcriptomes and Proteomes of Group A Streptococcus Biofilms

scientific article

Glucose Levels Alter the Mga Virulence Regulon in the Group A Streptococcus.

scientific article

Hemoglobin induces early and robust biofilm development in <i>Streptococcus pneumoniae</i> by a pathway that involves <i>comC</i> but not the cognate <i>comDE</i> two-component system

scientific article published on 04 January 2021

Identification of pyruvate kinase as an antigen associated with Tourette syndrome

scientific article published on 2 October 2006

Identification of residues in the Pseudomonas aeruginosa elastase propeptide required for chaperone and secretion activities

scientific article published on 01 December 2004

In vivo expression of Streptococcus pyogenes immunogenic proteins during tibial foreign body infection

scientific article

Investigating how streptococcus responds to their environment: bringing together current research, a case study and laboratory investigation

scientific article published on December 2011

Laboratory growth and maintenance of Streptococcus pyogenes (the Group A Streptococcus, GAS).

scientific article published on 02 October 2013

Mga is sufficient to activate transcription in vitro of sof-sfbX and other Mga-regulated virulence genes in the group A Streptococcus

scientific article

Mode of expression and functional characterization of FCT-3 pilus region-encoded proteins in Streptococcus pyogenes serotype M49.

scientific article published on 13 October 2008

MtsR is a dual regulator that controls virulence genes and metabolic functions in addition to metal homeostasis in the group A streptococcus

scientific article published on 14 April 2010

Nucleotides critical for the interaction of the Streptococcus pyogenes Mga virulence regulator with Mga-regulated promoter sequences

scientific article published on 6 July 2012

PTS Uptake and Metabolism of the ß-Glucoside Salicin Impacts Group A Streptococcal Bloodstream Survival and Soft Tissue Infection

scientific article published on 27 July 2020

PTS phosphorylation of Mga modulates regulon expression and virulence in the group A streptococcus.

scientific article published on 20 May 2013

Pseudomonas aeruginosa lasB1 mutants produce an elastase, substituted at active-site His-223, that is defective in activity, processing, and secretion.

scientific article

Role of Streptococcus pyogenes two-component response regulators in the temporal control of Mga and the Mga-regulated virulence gene emm.

scientific article

Role of mga in growth phase regulation of virulence genes of the group A streptococcus ⬇️

scientific article published on August 1, 1997

Route of Glucose Uptake in the Group a Streptococcus Impacts SLS-Mediated Hemolysis and Survival in Human Blood.

scientific article published on 14 March 2018

Shr is a broad-spectrum surface receptor that contributes to adherence and virulence in group A streptococcus

scientific article published on 18 August 2008

Skim milk enhances the preservation of thawed -80 degrees C bacterial stocks

scientific article published on 14 May 2008

Specific binding of the activator Mga to promoter sequences of the emm and scpA genes in the group A streptococcus.

scientific article

Streptococcal Lancefield polysaccharides are critical cell wall determinants for human Group IIA secreted phospholipase A2 to exert its bactericidal effects

scientific article published on 15 October 2018

Substitution of active-site His-223 in Pseudomonas aeruginosa elastase and expression of the mutated lasB alleles in Escherichia coli show evidence for autoproteolytic processing of proelastase.

scientific article

The Arginine Deiminase Pathway Impacts Antibiotic Tolerance during Biofilm-Mediated Streptococcus pyogenes Infections

scientific article published on 07 July 2020

The Mga virulence regulon: infection where the grass is greener.

scientific article

The Transcriptional Regulator CpsY Is Important for Innate Immune Evasion in Streptococcus pyogenes

scientific article published on 19 December 2016

The crimson conundrum: heme toxicity and tolerance in GAS.

scientific article

The elastase propeptide functions as an intramolecular chaperone required for elastase activity and secretion in Pseudomonas aeruginosa

scientific article published in December 1995

The endopeptidase PepO regulates the SpeB cysteine protease and is essential for the virulence of invasive M1T1 Streptococcus pyogenes

scientific article

The fruRBA Operon Is Necessary for Group A Streptococcal Growth in Fructose and for Resistance to Neutrophil Killing during Growth in Whole Human Blood

scientific article published on 19 January 2016

The phosphoenolpyruvate phosphotransferase system in group A Streptococcus acts to reduce streptolysin S activity and lesion severity during soft tissue infection

scientific article published on 30 December 2013

The scfCDE Operon Encodes a Predicted ABC Importer Required for Fitness and Virulence during Group A Streptococcus Invasive Infection

scientific article published on 18 November 2019

TrxR, a new CovR-repressed response regulator that activates the Mga virulence regulon in group A Streptococcus

scientific article

Two DNA-binding domains of Mga are required for virulence gene activation in the group A streptococcus.

scientific article

amrA encodes a putative membrane protein necessary for maximal exponential phase expression of the Mga virulence regulon in Streptococcus pyogenes

scientific article published in October 2003

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