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List of works by Jeremy H. Lakey

A carboxyl-terminal Cys2/His2-type zinc-finger motif in DNA primase influences DNA content in Synechococcus PCC 7942.

scientific article published in August 1998

A common interaction for the entry of colicin N and filamentous phage into Escherichia coli

scientific article published on 20 March 2009

A natively unfolded toxin domain uses its receptor as a folding template

scientific article published on 5 March 2004

A novel mechanism of pore formation: membrane penetration by the N-terminal amphipathic region of equinatoxin

scientific article published on 2 April 2003

A toxin-based probe reveals cytoplasmic exposure of Golgi sphingomyelin

scientific article published on 12 May 2010

Alhydrogel® adjuvant, ultrasonic dispersion and protein binding: A TEM and analytical study ⬇️

scientific article published on July 27, 2011

Amphipols: polymeric surfactants for membrane biology research.

scientific article published on August 2003

An Approach To Prepare Membrane Proteins for Single-Molecule Imaging

scientific article published on 01 May 2006

An accurate in vitro model of the E. coli envelope.

scientific article

An ion-channel-containing model membrane: structural determination by magnetic contrast neutron reflectometry

scientific article

An oomycete NLP cytolysin forms transient small pores in lipid membranes

scientific article published in 2022

Anthrax sub-unit vaccine: the structural consequences of binding rPA83 to Alhydrogel®.

scientific article

Antibacterial toxin colicin N and phage protein G3p compete with TolB for a binding site on TolA.

scientific article published on 23 December 2014

Assembly of pore proteins on gold electrodes.

scientific article

Asymmetric phospholipid: lipopolysaccharide bilayers; a Gram-negative bacterial outer membrane mimic

scientific article published on 16 October 2013

Brucella Omp2a and Omp2b porins: single channel measurements and topology prediction

scientific article published on 01 October 1997

Carbohydrates and glycoconjugates. Biophysical methods. Web alert

scientific article published on 01 October 2000

Characterisation of channels induced in planar bilayer membranes by detergent solubilised Escherichia coli porins

scientific article published in July 1985

Circular dichroism spectroscopy of folding in a protein monolayer

scientific article published on 01 July 2005

Cl-out is a novel cooperative optogenetic tool for extruding chloride from neurons.

scientific article published on 17 November 2016

Colicin N binds to the periphery of its receptor and translocator, outer membrane protein F.

scientific article published on March 2008

Colicin Pore-Forming Domains Bind toEscherichia ColiTrimeric Porins†

scientific article published on 01 July 2000

Comparative analysis of the QUTR transcription repressor protein and the three C-terminal domains of the pentafunctional AROM enzyme.

scientific article published on February 1996

Copper binding to the N-terminal tandem repeat region of mammalian and avian prion protein: structural studies using synthetic peptides

scientific article published on 01 September 1995

Determining OMP topology by computation, surface plasmon resonance and cysteine labelling: the test case of OMPG.

scientific article published on 10 October 2006

Determining the amphipol distribution within membrane-protein fibre samples using small-angle neutron scattering

Deuterium Labeling Strategies for Creating Contrast in Structure-Function Studies of Model Bacterial Outer Membranes Using Neutron Reflectometry.

scientific article published on 18 June 2015

Different sensitivities to acid denaturation within a family of proteins: implications for acid unfolding and membrane translocation.

scientific article

Differential selection of acridine resistance mutations in human DNA topoisomerase IIbeta is dependent on the acridine structure

article

Direct measurement of the association of a protein with a family of membrane receptors

scientific article published on 01 February 1996

Discovery of biphasic thermal unfolding of ompc with implications for surface loop stability

scientific article

Discovery of critical Tol A-binding residues in the bactericidal toxin colicin N: a biophysical approach

scientific article published in June 1998

Disparate proteins use similar architectures to damage membranes.

scientific article

Displacement of OmpF loop 3 is not required for the membrane translocation of colicins N and A in vivo

scientific article published on 01 August 1998

Distribution of mechanical stress in the Escherichia coli cell envelope

scientific article published on 29 September 2018

Effect of divalent cation removal on the structure of gram-negative bacterial outer membrane models.

scientific article

Emerging techniques for investigating molecular interactions at lipid membranes

scientific article published on 01 November 1998

Engineered mosaic protein polymers; a simple route to multifunctional biomaterials

scientific article published on 18 June 2019

Engineered self-assembling monolayers for label free detection of influenza nucleoprotein

scientific article

Enhanced cell attachment using a novel cell culture surface presenting functional domains from extracellular matrix proteins ⬇️

scientific article published on 25 January 2008

Examining Protein–Lipid Complexes Using Neutron Scattering

scientific article published on 01 January 2013

Expression of proteins using the third domain of the Escherichia coli periplasmic-protein TolA as a fusion partner.

scientific article published in March 2003

Gram-negative trimeric porins have specific LPS binding sites that are essential for porin biogenesis

scientific article published on 04 August 2016

Heat does not come in different colours: entropy-enthalpy compensation, free energy windows, quantum confinement, pressure perturbation calorimetry, solvation and the multiple causes of heat capacity effects in biomolecular interactions

scientific article published on 01 November 2001

Helix N-Cap Residues Drive the Acid Unfolding That Is Essential in the Action of the Toxin Colicin A

scientific article published on 13 November 2019

Helix orientations in membrane-associated Bcl-X(L) determined by 15N-solid-state NMR spectroscopy

scientific article published on 10 May 2007

High coverage fluid-phase floating lipid bilayers supported by ω-thiolipid self-assembled monolayers

scientific article published on September 2014

High level expression of His-tagged colicin pore-forming domains and reflections on the sites for pore formation in the inner membrane

scientific article published in May 2002

High-yield expression and purification of soluble forms of the anti-apoptotic Bcl-x(L) and Bcl-2 as TolAIII-fusion proteins.

scientific article

Human Miro Proteins Act as NTP Hydrolases through a Novel, Non-Canonical Catalytic Mechanism

scientific article published in 2018

Identification and characterization of the Pasteurella multocida toxin translocation domain.

scientific article published on October 2004

Immobilisation of proteins at silicon surfaces using undecenylaldehyde: demonstration of the retention of protein functionality and detection strategies

scientific article published on 17 December 2008

Immunogenicity of a Yersinia pestis vaccine antigen monomerized by circular permutation

scientific article

Increasing the potency of an alhydrogel-formulated anthrax vaccine by minimizing antigen-adjuvant interactions

scientific article

Insertion of the enteropathogenic Escherichia coli Tir virulence protein into membranes in vitro.

scientific article published on 24 January 2006

Interaction of the colicin-A pore-forming domain with negatively charged phospholipids

scientific article published on 01 February 1993

Interaction of transcription factors with serum response factor. Identification of the Elk-1 binding surface

scientific article published on 01 April 1998

Interfacial interactions of pore-forming colicins.

scientific article published on January 2010

Ion-Channel Gating in Transmembrane Receptor Proteins: Functional Activity in Tethered Lipid Membranes

scientific article published on 01 February 1999

Key residues in subsite F play a critical role in the activity of Pseudomonas fluorescens subspecies cellulosa xylanase A against xylooligosaccharides but not against highly polymeric substrates such as xylan.

scientific article published on January 1997

Kinetic analysis of human topoisomerase IIalpha and beta DNA binding by surface plasmon resonance.

scientific article

Liquid crystalline bacterial outer membranes are critical for antibiotic susceptibility

scientific article published on 23 July 2018

Low resolution structure and dynamics of a colicin-receptor complex determined by neutron scattering

scientific article published on 10 November 2011

Macromolecular assemblages. Theory and simulation

scientific article published on 01 April 2001

Macromolecular organisation of recombinantYersinia pestisF1 antigen and the effect of structure on immunogenicity ⬇️

scientific article published on July 1, 1998

Mannanase A from Pseudomonas fluorescens ssp. cellulosa is a retaining glycosyl hydrolase in which E212 and E320 are the putative catalytic residues.

scientific article

Measuring protein-protein interactions.

scientific article published on February 1998

Membrane insertion of the pore-forming domain of colicin A. A spectroscopic study

scientific article published on 01 March 1991

Modular Protein Engineering Approach to the Functionalization of Gold Nanoparticles for Use in Clinical Diagnostics

scientific article published on 28 June 2018

Molecular Determinants of Sphingomyelin Specificity of a Eukaryotic Pore-forming Toxin

scientific article published in Journal of Biological Chemistry

Molecular characterization of the B-box protein-protein interaction motif of the ETS-domain transcription factor Elk-1.

scientific article published on May 1997

Molecular, antigenic, and functional analyses of Omp2b porin size variants of Brucella spp

scientific article

Monitoring the assembly of antibody-binding membrane protein arrays using polarised neutron reflection

scientific article published on 4 March 2008

Mutation P732L in human DNA topoisomerase IIbeta abolishes DNA cleavage in the presence of calcium and confers drug resistance.

scientific article published on 20 October 2005

Neural differentiation regulated by biomimetic surfaces presenting motifs of extracellular matrix proteins

scientific article

Neutrons for biologists: a beginner's guide, or why you should consider using neutrons.

scientific article

Nucleic acids. Sequences and topology Web alert

scientific article published on 01 June 2001

Outer membrane protein F stabilised with minimal amphipol forms linear arrays and LPS-dependent 2D crystals.

scientific article published on March 2014

Peeking into a secret world of pore-forming toxins: membrane binding processes studied by surface plasmon resonance.

scientific article published on September 2003

Phage display selection of efficient glutamine-donor substrate peptides for transglutaminase 2

scientific article published in November 2006

Pore formation by equinatoxin, a eukaryotic pore-forming toxin, requires a flexible N-terminal region and a stable beta-sandwich

scientific article

Probing the orientation of yeast VDAC1 in vivo.

scientific article

Probing the structural basis for the difference in thermostability displayed by family 10 xylanases.

scientific article published on 15 May 2006

Production and characterization of a plant alpha-hydroxynitrile lyase in Escherichia coli

scientific article published in February 1997

Properties of nonfused liposomes immobilized on an L1 Biacore chip and their permeabilization by a eukaryotic pore-forming toxin

scientific article published in September 2005

Protein-nucleic acid interactions. Folding and binding

scientific article

Recombinant anthrax protective antigen: Observation of aggregation phenomena by TEM reveals specific effects of sterols

scientific article

Reversible non-stick behaviour of a bacterial protein polymer provides a tuneable molecular mimic for cell and tissue engineering

scientific article published on 13 March 2014

Role of hydrogen bonding in the interaction between a xylan binding module and xylan

scientific article

Self-Assembled Fluid Phase Floating Membranes with Tunable Water Interlayers

scientific article published on 08 October 2019

Self-Assembly of Protein Monolayers Engineered for Improved Monoclonal Immunoglobulin G Binding ⬇️

scientific article published on August 15, 2011

Self-recognition by an intrinsically disordered protein

scientific article published on 23 June 2008

Simple detection of protein soft structure changes

scientific article published on 01 April 2010

Single peptide bonds exhibit poly(pro)II ("random coil") circular dichroism spectra

scientific article published in July 2005

Spectroscopic study of the activation and oligomerization of the channel-forming toxin aerolysin: identification of the site of proteolytic activation.

scientific article published in September 1992

Stabilising and destabilising modifications of cysteines in the E. coli outer membrane porin protein OmpC.

scientific article published in July 1997

Stable self-assembly of a protein engineering scaffold on gold surfaces

scientific article

Sterol and pH Interdependence in the Binding, Oligomerization, and Pore Formation of Listeriolysin O†

scientific article published on 15 March 2007

Structural characterization of a model gram-negative bacterial surface using lipopolysaccharides from rough strains of Escherichia coli

scientific article published on 09 May 2013

Surface aspartate residues are essential for the stability of colicin A P-domain: a mechanism for the formation of an acidic molten-globule

scientific article published in February 2002

The Effect of Lipopolysaccharide Core Oligosaccharide Size on the Electrostatic Binding of Antimicrobial Proteins to Models of the Gram Negative Bacterial Outer Membrane

scientific article

The TolA-recognition site of colicin N. ITC, SPR and stopped-flow fluorescence define a crucial 27-residue segment

scientific article published on 01 December 2000

The Two-State Prehensile Tail of the Antibacterial Toxin Colicin N.

scientific article published in October 2017

The alpha-glucuronidase, GlcA67A, of Cellvibrio japonicus utilizes the carboxylate and methyl groups of aldobiouronic acid as important substrate recognition determinants

scientific article (publication date: 30 May 2003)

The antibacterial toxin colicin N binds to the inner core of lipopolysaccharide and close to its translocator protein

scientific article published on 28 March 2014

The bacterial porin superfamily: sequence alignment and structure prediction.

scientific article

The central domain of colicin N possesses the receptor recognition site but not the binding affinity of the whole toxin.

scientific article

The influence of secretory-protein charge on late stages of secretion from the Gram-positive bacterium Bacillus subtilis.

scientific article published on August 2000

The pasteurella multocida toxin interacts with signalling pathways to perturb cell growth and differentiation.

scientific article published on April 2004

The role of electrostatic charge in the membrane insertion of colicin A. Calculation and mutation.

scientific article

The structural orientation of antibody layers bound to engineered biosensor surfaces.

scientific article published in April 2011

The structure of Yersinia pestis Caf1 polymer in free and adjuvant bound states.

scientific article published on 18 June 2010

The unstructured domain of colicin N kills Escherichia coli

scientific article published on 5 June 2013

The use of forced protein evolution to investigate and improve stability of family 10 xylanases. The production of Ca2+-independent stable xylanases

scientific article published on 27 September 2004

The voltage-dependent activity of Escherichia coli porins in different planar bilayer reconstitutions.

scientific article

Thermal stability and rheological properties of the 'non-stick' Caf1 biomaterial.

scientific article published on 20 June 2017

Tuneable hydrogels of Caf1 protein fibers

scientific article published on 24 July 2018

Two-step membrane binding by Equinatoxin II, a pore-forming toxin from the sea anemone, involves an exposed aromatic cluster and a flexible helix

scientific article published on 26 August 2002

Unfolding transitions of Bacillus anthracis protective antigen

scientific article published on 11 May 2007

Voltage gating is a fundamental feature of porin and toxin β‐barrel membrane channels ⬇️

scientific article published on July 24, 1998

Voltage-gating of Escherichia coli porin: a cystine-scanning mutagenesis study of loop 3 1 1Edited by I. B. Holland ⬇️

scientific article published on January 16, 1998

Web alert. Proteins catalysis and regulation

scientific article published on 01 December 2000

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