List of works - Andrew J Doig

A critical assessment of the secondary structure alpha-helices and their termini in proteins.

scientific article

A phosphoserine-lysine salt bridge within an alpha-helical peptide, the strongest alpha-helix side-chain interaction measured to date.

scientific article

A simple approach to normalization for spectroscopic data mining

scientific article

Accurate determination of protein secondary structure content from Raman and Raman optical activity spectra

scientific article published in August 2010

Addition of side chain interactions to modified Lifson-Roig helix-coil theory: application to energetics of phenylalanine-methionine interactions.

scientific article published on November 1995

Addition of side-chain interactions to 3(10)-helix/coil and alpha-helix/3(10)-helix/coil theory.

scientific article published on November 1998

Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies

scientific article

Amyloid-β/Drug Interactions from Computer Simulations and Cell-Based Assays

scientific article published on 01 January 2018

Anticooperativity in a Glu-Lys-Glu salt bridge triplet in an isolated alpha-helical peptide.

scientific article

Combined experimental and simulation studies suggest a revised mode of action of the anti-Alzheimer disease drug NQ-Trp

scientific article

Design of an N-methylated peptide inhibitor of alpha-synuclein aggregation guided by solid-state NMR.

scientific article published on 30 May 2008

Design strategies for anti-amyloid agents.

scientific article

Determination of Protein Secondary Structure from Infrared Spectra Using Partial Least-Squares Regression

scientific article

Determination of free energies of N-capping in alpha-helices by modification of the Lifson-Roig helix-coil therapy to include N- and C-capping.

scientific article published in March 1994

Distinguishing enzyme structures from non-enzymes without alignments

scientific article published in July 2003

Drug repurposing: progress, challenges and recommendations

scholarly article by Sudeep Pushpakom et al published 12 October 2018 in Nature Reviews Drug Discovery

Effect of IAPP on the proteome of cultured Rin-5F cells

scholarly article by Samaneh Miraee-Nedjad published in November 2018

Effect of phosphorylation on alpha-helix stability as a function of position.

scientific article published in February 2002

Effect of the N1 residue on the stability of the alpha-helix for all 20 amino acids

scientific article

Effect of the N3 residue on the stability of the alpha-helix.

scientific article published on January 2004

Fewer academics could be the answer to insufficient grants

scientific article published in June 2008

Free energies of amino acid side-chain rotamers in alpha-helices, beta-sheets and alpha-helix N-caps

scientific article published in September 1997

Frozen, but no accident - why the 20 standard amino acids were selected.

scientific article

Hepatotoxic and nephrotoxic principles in Terminalia oblongata

scientific article published on 01 March 1991

Hydrogen bonding interactions between glutamine and asparagine in α-helical peptides 1 1Edited by A. R. Fersht

scientific article published on 01 September 1997

Identifying mouse developmental essential genes using machine learning

article

Improving the Efficiency of the Genetic Code by Varying the Codon Length—The Perfect Genetic Code ⬇️

scientific article published on October 7, 1997

Information-theoretic analysis of protein sequences shows that amino acids self-cluster

scientific article published on 01 October 2002

Inhibition of protein aggregation and amyloid formation by small molecules

scientific article published on 2 January 2015

Inhibition of toxicity and protofibril formation in the amyloid-beta peptide beta(25-35) using N-methylated derivatives

scientific article published in August 2002

Inhibition of toxicity in the beta-amyloid peptide fragment beta -(25-35) using N-methylated derivatives: a general strategy to prevent amyloid formation

scientific article published in August 2000

Inhibitors of amyloid aggregation: technologies for the discovery of novel lead compounds.

scientific article published on January 2004

Is polyproline II helix the killer conformation? a raman optical activity study of the amyloidogenic prefibrillar intermediate of human lysozyme 1 1Edited by A. R. Fersht

scientific article published on 01 August 2000

Is the hydrophobic effect stabilizing or destabilizing in proteins?

scientific article published on 01 January 1991

Length preferences and periodicity in beta-strands. Antiparallel edge beta-sheets are more likely to finish in non-hydrogen bonded rings

scientific article published in December 2003

Local control of a disorder-order transition in 4E-BP1 underpins regulation of translation via eIF4E.

scientific article

Maximising the size of non-redundant protein datasets using graph theory

scientific article

Models for the 3(10)-helix/coil, pi-helix/coil, and alpha-helix/3(10)-helix/coil transitions in isolated peptides

scientific article

Molecular structure of the NQTrp inhibitor with the Alzheimer Aβ1-28 monomer

scientific article

N-Methylated peptide inhibitors of beta-amyloid aggregation and toxicity. Optimization of the inhibitor structure

scientific article

N‐ and C‐capping preferences for all 20 amino acids in α‐helical peptides ⬇️

scientific article published on July 1, 1995

Pairwise coupling in an Arg-Phe-Met triplet stabilizes alpha-helical peptide via shared rotamer preferences

scientific article

Peptide inhibitors of beta-amyloid aggregation.

scientific article published on September 2007

Periodicity in alpha-helix lengths and C-capping preferences

scientific article published in November 1999

Prediction of Saccharomyces cerevisiae protein functional class from functional domain composition.

scientific article

Prediction of protein function in the absence of significant sequence similarity.

scientific article published in August 2004

Properties and identification of antibiotic drug targets

scientific article

Properties and identification of human protein drug targets

scientific article

Properties of genes essential for mouse development

scientific article

Properties of protein drug target classes

scientific article

Quantification of protein glycation using vibrational spectroscopy

scientific article published on 22 April 2020

Random-coil:α-helix equilibria as a reporter for the Lewis(X)-Lewis(X) interaction.

scientific article

Recent advances in helix-coil theory.

scientific article

Secondary Structure and Glycosylation of Mucus Glycoproteins by Raman Spectroscopies

scientific article (publication date: 6 December 2016)

Sequence and Structural Features of Enzymes and their Active Sites by EC Class

scientific article published on 10 December 2008

Side-chain structures in the first turn of the α-helix 1 1Edited by J. M. Thornton

scientific article published on 01 March 1999

SitesIdentify: a protein functional site prediction tool

scientific article

Stability and design of alpha-helical peptides.

scientific article published on January 2008

Stabilizing interactions between aromatic and basic side chains in alpha-helical peptides and proteins. Tyrosine effects on helix circular dichroism

scientific article published in October 2002

Stabilizing nonpolar/polar side-chain interactions in the alpha-helix

scientific article published in December 2001

Statistical thermodynamics of the collagen triple-helix/coil transition. Free energies for amino acid substitutions within the triple-helix

scientific article published in November 2008

Structure and Stability of the α-Helix: Lessons for Design

article

Structure, stability and folding of the alpha-helix

article

Structures of N-termini of helices in proteins

scientific article

Studies of the aggregation of an amyloidogenic α-synuclein peptide fragment

scientific article published on 01 November 2005

The Essentiality Status of Mouse Duplicate Gene Pairs Correlates with Developmental Co-Expression Patterns

article

The N-methylated peptide SEN304 powerfully inhibits Aβ(1-42) toxicity by perturbing oligomer formation

scientific article published on 12 October 2012

The effects of alpha-synuclein on phospholipid vesicle integrity: a study using 31P NMR and electron microscopy.

scientific article published in September 2008

Thermodynamics of amino acid side-chain internal rotations

scientific article published in October 1996

Why Is Research on Amyloid-β Failing to Give New Drugs for Alzheimer's Disease?

scientific article published on 6 June 2017

Why water-soluble, compact, globular proteins have similar specific enthalpies of unfolding at 110.degree.C

scientific article published on 01 October 1992

List of works by Andrew J Doig

A critical assessment of the secondary structure alpha-helices and their termini in proteins.

A phosphoserine-lysine salt bridge within an alpha-helical peptide, the strongest alpha-helix side-chain interaction measured to date.

A simple approach to normalization for spectroscopic data mining

Accurate determination of protein secondary structure content from Raman and Raman optical activity spectra

Addition of side chain interactions to modified Lifson-Roig helix-coil theory: application to energetics of phenylalanine-methionine interactions.

Addition of side-chain interactions to 3(10)-helix/coil and alpha-helix/3(10)-helix/coil theory.

Amyloid β Protein and Alzheimer's Disease: When Computer Simulations Complement Experimental Studies

Amyloid-β/Drug Interactions from Computer Simulations and Cell-Based Assays

Anticooperativity in a Glu-Lys-Glu salt bridge triplet in an isolated alpha-helical peptide.

Combined experimental and simulation studies suggest a revised mode of action of the anti-Alzheimer disease drug NQ-Trp

Design of an N-methylated peptide inhibitor of alpha-synuclein aggregation guided by solid-state NMR.

Design strategies for anti-amyloid agents.

Determination of Protein Secondary Structure from Infrared Spectra Using Partial Least-Squares Regression

Determination of free energies of N-capping in alpha-helices by modification of the Lifson-Roig helix-coil therapy to include N- and C-capping.

Distinguishing enzyme structures from non-enzymes without alignments

Drug repurposing: progress, challenges and recommendations

Effect of IAPP on the proteome of cultured Rin-5F cells

Effect of phosphorylation on alpha-helix stability as a function of position.

Effect of the N1 residue on the stability of the alpha-helix for all 20 amino acids

Effect of the N3 residue on the stability of the alpha-helix.

Fewer academics could be the answer to insufficient grants

Free energies of amino acid side-chain rotamers in alpha-helices, beta-sheets and alpha-helix N-caps

Frozen, but no accident - why the 20 standard amino acids were selected.

Hepatotoxic and nephrotoxic principles in Terminalia oblongata

Hydrogen bonding interactions between glutamine and asparagine in α-helical peptides 1 1Edited by A. R. Fersht

Identifying mouse developmental essential genes using machine learning

Improving the Efficiency of the Genetic Code by Varying the Codon Length—The Perfect Genetic Code ⬇️

Information-theoretic analysis of protein sequences shows that amino acids self-cluster

Inhibition of protein aggregation and amyloid formation by small molecules

Inhibition of toxicity and protofibril formation in the amyloid-beta peptide beta(25-35) using N-methylated derivatives

Inhibition of toxicity in the beta-amyloid peptide fragment beta -(25-35) using N-methylated derivatives: a general strategy to prevent amyloid formation

Inhibitors of amyloid aggregation: technologies for the discovery of novel lead compounds.

Is polyproline II helix the killer conformation? a raman optical activity study of the amyloidogenic prefibrillar intermediate of human lysozyme 1 1Edited by A. R. Fersht

Is the hydrophobic effect stabilizing or destabilizing in proteins?

Length preferences and periodicity in beta-strands. Antiparallel edge beta-sheets are more likely to finish in non-hydrogen bonded rings

Local control of a disorder-order transition in 4E-BP1 underpins regulation of translation via eIF4E.

Maximising the size of non-redundant protein datasets using graph theory

Models for the 3(10)-helix/coil, pi-helix/coil, and alpha-helix/3(10)-helix/coil transitions in isolated peptides

Molecular structure of the NQTrp inhibitor with the Alzheimer Aβ1-28 monomer

N-Methylated peptide inhibitors of beta-amyloid aggregation and toxicity. Optimization of the inhibitor structure

N‐ and C‐capping preferences for all 20 amino acids in α‐helical peptides ⬇️

Pairwise coupling in an Arg-Phe-Met triplet stabilizes alpha-helical peptide via shared rotamer preferences

Peptide inhibitors of beta-amyloid aggregation.

Periodicity in alpha-helix lengths and C-capping preferences

Prediction of Saccharomyces cerevisiae protein functional class from functional domain composition.

Prediction of protein function in the absence of significant sequence similarity.

Properties and identification of antibiotic drug targets

Properties and identification of human protein drug targets

Properties of genes essential for mouse development

Properties of protein drug target classes

Quantification of protein glycation using vibrational spectroscopy

Random-coil:α-helix equilibria as a reporter for the Lewis(X)-Lewis(X) interaction.

Recent advances in helix-coil theory.

Secondary Structure and Glycosylation of Mucus Glycoproteins by Raman Spectroscopies

Sequence and Structural Features of Enzymes and their Active Sites by EC Class

Side-chain structures in the first turn of the α-helix 1 1Edited by J. M. Thornton

SitesIdentify: a protein functional site prediction tool

Stability and design of alpha-helical peptides.

Stabilizing interactions between aromatic and basic side chains in alpha-helical peptides and proteins. Tyrosine effects on helix circular dichroism

Stabilizing nonpolar/polar side-chain interactions in the alpha-helix

Statistical thermodynamics of the collagen triple-helix/coil transition. Free energies for amino acid substitutions within the triple-helix

Structure and Stability of the α-Helix: Lessons for Design

Structure, stability and folding of the alpha-helix

Structures of N-termini of helices in proteins

Studies of the aggregation of an amyloidogenic α-synuclein peptide fragment

The Essentiality Status of Mouse Duplicate Gene Pairs Correlates with Developmental Co-Expression Patterns

The N-methylated peptide SEN304 powerfully inhibits Aβ(1-42) toxicity by perturbing oligomer formation

The effects of alpha-synuclein on phospholipid vesicle integrity: a study using 31P NMR and electron microscopy.

Thermodynamics of amino acid side-chain internal rotations

Why Is Research on Amyloid-β Failing to Give New Drugs for Alzheimer's Disease?

Why water-soluble, compact, globular proteins have similar specific enthalpies of unfolding at 110.degree.C