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List of works by Hitoshi Kurumizaka

A FancD2-monoubiquitin fusion reveals hidden functions of Fanconi anemia core complex in DNA repair

scientific article published on September 2005

A Genetically Encoded Probe for Live-Cell Imaging of H4K20 Monomethylation

scientific article

A chimeric Rec-A protein that implicates non-Watson-Crick interactions in homologous pairing

scientific article published on August 1994

A chromatin integration labelling method enables epigenomic profiling with lower input

scientific article published on 10 December 2018

A common mechanism for the ATP-DnaA-dependent formation of open complexes at the replication origin

scientific article

A method for evaluating nucleosome stability with a protein-binding fluorescent dye.

scientific article published on 8 September 2014

A possible role of the C-terminal domain of the RecA protein. A gateway model for double-stranded DNA binding

scientific article published on 01 December 1996

ATR-ATRIP kinase complex triggers activation of the Fanconi anemia DNA repair pathway

scientific article

Acetylated histone H4 tail enhances histone H3 tail acetylation by altering their mutual dynamics in the nucleosome

scientific article published on 03 August 2020

Activation of the FA pathway mediated by phosphorylation and ubiquitination

scientific article published on 5 May 2017

Activation of the SUMO modification system is required for the accumulation of RAD51 at sites of DNA damage

scientific article published on 17 September 2013

Altered DNA binding by the human Rad51-R150Q mutant found in breast cancer patients

scientific article published in August 2007

An interaction between a specified surface of the C-terminal domain of RecA protein and double-stranded DNA for homologous pairing

scientific article published on 28 November 1997

Association of M18BP1/KNL2 with CENP-A Nucleosome Is Essential for Centromere Formation in Non-mammalian Vertebrates

scientific article published in July 2017

Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

scientific article published in Nature Communications

Author Correction: CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

scientific article published on 02 May 2019

Biochemical analysis of the N-terminal domain of human RAD54B

scientific article published on 20 August 2008

Biochemical analysis of the human DMC1-I37N polymorphism

scientific article

Biochemical analysis of the human ENA/VASP-family proteins, MENA, VASP and EVL, in homologous recombination

scientific article published on 11 March 2011

Biochemical analysis of the human EVL domains in homologous recombination

scientific article

Bivalent interaction of the PZP domain of BRPF1 with the nucleosome impacts chromatin dynamics and acetylation

scientific article

C-terminal acidic domain of histone chaperone human NAP1 is an efficient binding assistant for histone H2A-H2B, but not H3-H4.

scientific article published on 4 February 2016

CHD3 helicase domain mutations cause a neurodevelopmental syndrome with macrocephaly and impaired speech and language

scientific article published in Nature Communications

Cancer-associated mutations of histones H2B, H3.1 and H2A.Z.1 affect the structure and stability of the nucleosome

scientific article published on 01 November 2018

Cdt1-binding protein GRWD1 is a novel histone-binding protein that facilitates MCM loading through its influence on chromatin architecture

scientific journal article

Charge-neutralization effect of the tail regions on the histone H2A/H2B dimer structure.

scientific article published on 3 April 2015

Chd2 interacts with H3.3 to determine myogenic cell fate

scientific journal article

Chromatin architecture may dictate the target site for DMC1, but not for RAD51, during homologous pairing

scientific article published on 7 April 2016

Chromatin integration labeling for mapping DNA-binding proteins and modifications with low input

scientific article published on 17 August 2020

Compensatory functions and interdependency of the DNA-binding domain of BRCA2 with the BRCA1-PALB2-BRCA2 complex

scientific article published on 27 November 2013

Comprehensive structural analysis of mutant nucleosomes containing lysine to glutamine (KQ) substitutions in the H3 and H4 histone-fold domains

scientific article

Conclusive evidence of the reconstituted hexasome proven by native mass spectrometry

scientific article

Contribution of histone N-terminal tails to the structure and stability of nucleosomes

scientific article

Corrigendum to: Contribution of histone N-terminal tails to the structure and stability of nucleosomes

scholarly article published in FEBS Open Bio

CpG methylation of the CENP-B box reduces human CENP-B binding

scientific article

Cryo-EM structure of the nucleosome containing the ALB1 enhancer DNA sequence

scientific article published in March 2018

Cryo-EM structure of the nucleosome core particle containing Giardia lamblia histones

scientific article published on 01 September 2021

Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8.

scientific article published on 4 April 2017

Crystal structure and stable property of the cancer-associated heterotypic nucleosome containing CENP-A and H3.3.

scientific article

Crystal structure of the CENP-B protein-DNA complex: the DNA-binding domains of CENP-B induce kinks in the CENP-B box DNA.

scientific article

Crystal structure of the homologous-pairing domain from the human Rad52 recombinase in the undecameric form

scientific article

Crystal structure of the human centromere protein B (CENP-B) dimerization domain at 1.65-A resolution

scientific article

Crystal structure of the human centromeric nucleosome containing CENP-A

scientific article

Crystal structure of the nucleosome containing histone H3 with crotonylated lysine 122

scientific article

Crystal structure of the nucleosome containing ultraviolet light-induced cyclobutane pyrimidine dimer

scientific article

Crystal structure of the overlapping dinucleosome composed of hexasome and octasome.

scientific article published in April 2017

Crystal structures of heterotypic nucleosomes containing histones H2A.Z and H2A

scientific article published on June 2016

Crystallization and preliminary X-ray diffraction analysis of the secreted protein Athe_0614 from Caldicellulosiruptor bescii

scientific article published on 28 March 2013

Current progress on structural studies of nucleosomes containing histone H3 variants

scientific article published on 22 December 2012

DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange

scientific article

DNA binding properties of the actin-related protein Arp8 and its role in DNA repair

scientific article

DNA robustly stimulates FANCD2 monoubiquitylation in the complex with FANCI.

scientific article published on 28 January 2012

Defective FANCI binding by a fanconi anemia-related FANCD2 mutant

scientific article published on 9 December 2014

Deimination stabilizes histone H2A/H2B dimers as revealed by electrospray ionization mass spectrometry

scientific article published on August 2010

Direct inhibition of TNF-α promoter activity by Fanconi anemia protein FANCD2.

scientific article

Distinct features of the histone core structure in nucleosomes containing the histone H2A.B variant

scientific article published on May 2014

Dynamic changes in CCAN organization through CENP-C during cell-cycle progression

scientific article

Dynamics in the transmission of genetic information: from meiosis to postmeiotic events.

scientific article

Enhancing survival of mouse oocytes following chemotherapy or aging by targeting Bax and Rad51

scientific article

Evaluation of chemical fluorescent dyes as a protein conjugation partner for live cell imaging

scientific article

Expression and purification of human FANCI and FANCD2 using Escherichia coli cells

scientific article published on 26 August 2014

Expression and purification of recombinant human histones

scientific article published in May 2004

FANCD2 binds CtIP and regulates DNA-end resection during DNA interstrand crosslink repair.

scientific article published in May 2014

FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5'-DNA end.

scientific article published on 30 September 2016

Filament formation and robust strand exchange activities of the rice DMC1A and DMC1B proteins

scientific article

From meiosis to postmeiotic events: uncovering the molecular roles of the meiosis-specific recombinase Dmc1.

scientific article published on 15 December 2009

Functional analyses of the C-terminal half of the Saccharomyces cerevisiae Rad52 protein

scientific article published on 25 October 2013

GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler

scientific article published on 27 February 2016

GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination

scientific article

Gas-phase structure of the histone multimers characterized by ion mobility mass spectrometry and molecular dynamics simulation.

scientific article published on 29 March 2013

Genetic variance modifies apoptosis susceptibility in mature oocytes via alterations in DNA repair capacity and mitochondrial ultrastructure

scientific article published on 13 October 2006

Genetically encoded system to track histone modification in vivo

scientific article published on January 2013

H3K14 ubiquitylation promotes H3K9 methylation for heterochromatin assembly

scientific article published on 29 August 2019

HIV-1 Vpr induces ATM-dependent cellular signal with enhanced homologous recombination

article

HIV-1 Vpr induces DNA double-strand breaks

scientific article published in January 2006

Halenaquinone, a chemical compound that specifically inhibits the secondary DNA binding of RAD51.

scientific article

Histone H2A variants confer specific properties to nucleosomes and impact on chromatin accessibility

scientific article published on 01 September 2018

Histone H3 Methylated at Arginine 17 Is Essential for Reprogramming the Paternal Genome in Zygotes

scientific article published in September 2017

Histone H3.3 sub-variant H3mm7 is required for normal skeletal muscle regeneration

scientific article published on 11 April 2018

Histone H3.5 forms an unstable nucleosome and accumulates around transcription start sites in human testis

scientific article published on 15 January 2016

Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2.

scientific article published on 21 June 2018

Histone Variant H2A.L.2 Guides Transition Protein-Dependent Protamine Assembly in Male Germ Cells.

scientific article

Histone acetylation: influence on transcription, nucleosome mobility and positioning, and linker histone-dependent transcriptional repression

scientific article

Histone chaperone activity of Fanconi anemia proteins, FANCD2 and FANCI, is required for DNA crosslink repair

scientific article

Holliday junction binding activity of the human Rad51B protein

scientific article

Holliday junction-binding activity of human SPF45

scientific article published on 04 March 2010

Homologous pairing activities of two rice RAD51 proteins, RAD51A1 and RAD51A2

scientific article (publication date: 2013)

Homologous pairing and ring and filament structure formation activities of the human Xrcc2*Rad51D complex

scientific article

Homologous pairing promoted by the human Rad52 protein

scientific article published on 13 July 2001

Homologous-pairing activity of the human DNA-repair proteins Xrcc3.Rad51C

scientific article

Human FAN1 promotes strand incision in 5'-flapped DNA complexed with RPA.

scientific article published on 27 April 2015

Human PSF binds to RAD51 and modulates its homologous-pairing and strand-exchange activities

scientific article published on 15 May 2009

Human PSF concentrates DNA and stimulates duplex capture in DMC1-mediated homologous pairing

scientific article published on 9 December 2011

Human Rad51 amino acid residues required for Rad52 binding.

scientific article

Human centromere protein B induces translational positioning of nucleosomes on alpha-satellite sequences

scientific article

Human tNASP promotes in vitro nucleosome assembly with histone H3.3

scientific article

Identification of a second DNA binding site in the human Rad52 protein

scientific article published on July 2008

Identification of functional domains of the Escherichia coli SeqA protein

scientific article published on 01 January 2003

Identification of the amino acid residues responsible for stable nucleosome formation by histone H3.Y.

scientific article published on 24 January 2017

In vivo and in vitro footprinting of nucleosomes and transcriptional activators using an infrared-fluorescence DNA sequencer

scientific article published in February 2008

Incorporation of DUF/FACT into chromatin enhances the accessibility of nucleosomal DNA

scientific article published on 01 March 2003

Independent and sequential recruitment of NHEJ and HR factors to DNA damage sites in mammalian cells

scientific article published in August 2005

Influence of DNA methylation on positioning and DNA flexibility of nucleosomes with pericentric satellite DNA.

scientific article published on October 2015

Influence of polynucleosome preparation methods on sedimentation velocity analysis of chromatin

scientific article published on 22 December 2016

Inhibition of filament formation of human Rad51 protein by a small peptide derived from the BRC-motif of the BRCA2 protein

scientific article published on 01 May 2008

Integral approach to biomacromolecular structure by analytical-ultracentrifugation and small-angle scattering

scientific article published on 08 June 2020

Interaction between basic residues of Epstein-Barr virus EBNA1 protein and cellular chromatin mediates viral plasmid maintenance

scientific article

Interaction of the pioneer transcription factor GATA3 with nucleosomes

scientific article published on 18 August 2020

Involvement of SLX4 in interstrand cross-link repair is regulated by the Fanconi anemia pathway

scientific article

In vitro reconstitution and biochemical analyses of the Schizosaccharomyces pombe nucleosome.

scientific article published on 24 November 2016

KIAA1018/FAN1 nuclease protects cells against genomic instability induced by interstrand cross-linking agents

scientific article

LC-MS/MS-based quantitative study of the acyl group- and site-selectivity of human sirtuins to acylated nucleosomes

scientific article published on 8 February 2018

Location of tyrosine 315, a target for phosphorylation by cAbl tyrosine kinase, at the edge of the subunit-subunit interface of the human Rad51 filament

scientific article

MNase, as a probe to study the sequence-dependent site exposures in the +1 nucleosomes of yeast.

scientific article published in August 2018

Mass spectrometric approach for characterizing the disordered tail regions of the histone H2A/H2B dimer

scientific article published on 29 January 2015

Methods for Preparing Nucleosomes Containing Histone Variants

scientific article published on 01 January 2018

Mislocalization of the centromeric histone variant CenH3/CENP-A in human cells depends on the chaperone DAXX.

scientific article published on 13 February 2014

Modeling population size independent tissue epigenomes by ChIL-seq with single thin sections

scientific article published on 01 November 2021

Mutational analyses of the human Rad51-Tyr315 residue, a site for phosphorylation in leukaemia cells

scientific article

Mutations in the gene encoding the E2 conjugating enzyme UBE2T cause Fanconi anemia

scientific article published on June 2015

N-terminal phosphorylation of HP1α increases its nucleosome-binding specificity

scientific article

Nap1 regulates proper CENP-B binding to nucleosomes

scientific article published on 15 January 2013

Nap1 stimulates homologous recombination by RAD51 and RAD54 in higher-ordered chromatin containing histone H1.

scientific article

Nucleosome destabilization by nuclear non-coding RNAs

scientific article published on 11 February 2020

Nucleosome formation activity of human somatic nuclear autoantigenic sperm protein (sNASP).

scientific article published on 18 February 2010

Nucleosome formation with the testis-specific histone H3 variant, H3t, by human nucleosome assembly proteins in vitro

scientific article published on 16 February 2008

Nucleosome organization and chromatin dynamics in telomeres

scientific article published on March 2015

Parallel mapping with site-directed hydroxyl radicals and micrococcal nuclease reveals structural features of positioned nucleosomes in vivo.

scientific article published on 26 October 2017

Phosphorylation of CBX2 controls its nucleosome-binding specificity

scientific article published on 16 June 2017

Polymorphism of apyrimidinic DNA structures in the nucleosome

scientific article published on 31 January 2017

Positive role of the mammalian TBPIP/HOP2 protein in DMC1-mediated homologous pairing.

scientific article published on 10 June 2004

Preferential binding to branched DNA strands and strand-annealing activity of the human Rad51B, Rad51C, Rad51D and Xrcc2 protein complex

scientific article

Proton NMR study on a histone-like protein, HU alpha, from Escherichia coli and its complex with oligo DNAs.

scientific article

Purification and characterization of the fission yeast telomere clustering factors, Bqt1 and Bqt2.

scientific article published on 19 January 2013

Purification of the human SMN-GEMIN2 complex and assessment of its stimulation of RAD51-mediated DNA recombination reactions

scientific article

RAD51 plays a crucial role in halting cell death program induced by ionizing radiation in bovine oocytes.

scientific article published on 19 March 2012

RFWD3-Mediated Ubiquitination Promotes Timely Removal of Both RPA and RAD51 from DNA Damage Sites to Facilitate Homologous Recombination

scientific article

Recombination activator function of the novel RAD51- and RAD51B-binding protein, human EVL.

scientific article published on 26 March 2009

Region and amino acid residues required for Rad51C binding in the human Xrcc3 protein.

scientific article published on July 2003

Relaxed Chromatin Formation and Weak Suppression of Homologous Pairing by the Testis-Specific Linker Histone H1T.

scientific article published on 12 January 2016

Replication stress induces accumulation of FANCD2 at central region of large fragile genes.

scientific article published on 31 January 2018

Role of the N-terminal domain of the human DMC1 protein in octamer formation and DNA binding

scientific article

Roles of histone H3.5 in human spermatogenesis and spermatogenic disorders.

scientific article published on 27 November 2017

Roles of the human Rad51 L1 and L2 loops in DNA binding

scientific article

SUMO modification system facilitates the exchange of histone variant H2A.Z-2 at DNA damage sites

scientific article published on 2 November 2017

SYCP3 regulates strand invasion activities of RAD51 and DMC1.

scientific article published on 26 July 2017

Sequence-directed nucleosome-depletion is sufficient to activate transcription from a yeast core promoter in vivo

scientific article

Single-stranded DNA catenation mediated by human EVL and a type I topoisomerase

scientific article published on 17 July 2010

Solution structure of the DNA binding domain of a nucleoid-associated protein, H-NS, from Escherichia coli

scientific article

Solution structure of variant H2A.Z.1 nucleosome investigated by small-angle X-ray and neutron scatterings

scientific article published on 28 August 2015

Specific and nonspecific interactions of integration host factor with oligo DNAs as revealed by circular dichroism spectroscopy and filter binding assay

scientific article published on 01 June 1992

Specific defects in double-stranded DNA unwinding and homologous pairing of a mutant RecA protein

scientific article published on 01 July 2000

Stable complex formation of CENP-B with the CENP-A nucleosome

scientific article published on 27 April 2015

Stimulation of DNA strand exchange by the human TBPIP/Hop2-Mnd1 complex.

scientific article

Stimulation of Dmc1-mediated DNA strand exchange by the human Rad54B protein

scientific article

Structural Basis of Heterochromatin Formation by Human HP1.

scientific article published on 10 January 2018

Structural Diversity of Nucleosomes Characterized by Native Mass Spectrometry

scientific article published on 12 June 2018

Structural analysis of the hexasome, lacking one histone H2A/H2B dimer from the conventional nucleosome

scientific article published on 02 April 2012

Structural analysis of the human Rad51 protein-DNA complex filament by tryptophan fluorescence scanning analysis: transmission of allosteric effects between ATP binding and DNA binding

scientific article published on 22 August 2008

Structural and biochemical analyses of hemimethylated DNA binding by the SeqA protein

scientific article

Structural and biochemical analyses of monoubiquitinated human histones H2B and H4.

scientific article

Structural and biochemical analyses of the human PAD4 variant encoded by a functional haplotype gene

scientific article

Structural and biochemical analyses of the nuclear pore complex component ELYS identify residues responsible for nucleosome binding

scientific article published on 03 May 2019

Structural and functional analyses of the DMC1-M200V polymorphism found in the human population

scientific article

Structural basis for octameric ring formation and DNA interaction of the human homologous-pairing protein Dmc1.

scientific article

Structural basis for the DNA-binding activity of the bacterial β-propeller protein YncE

scientific article

Structural basis for the inhibition of cGAS by nucleosomes

scientific article

Structural basis of a nucleosome containing histone H2A.B/H2A.Bbd that transiently associates with reorganized chromatin

scientific article

Structural basis of instability of the nucleosome containing a testis-specific histone variant, human H3T

scientific article

Structural basis of pyrimidine-pyrimidone (6-4) photoproduct recognition by UV-DDB in the nucleosome

scientific article published on 17 November 2015

Structural basis of replication origin recognition by the DnaA protein

scientific article (publication date: 15 April 2003)

Structural basis of the nucleosome transition during RNA polymerase II passage

scientific article

Structural diversity of the nucleosome

scientific article published on 17 November 2017

Structural insight into nucleosome transcription by RNA polymerase II with elongation factors

scientific article

Structural polymorphism in the L1 loop regions of human H2A.Z.1 and H2A.Z.2

scientific article

Structural polymorphism of the Escherichia coli poly-α-L-glutamate synthetase RimK

scientific article published on 26 June 2018

Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.

scientific article published on May 2017

Structure and Dynamics of a 197 bp Nucleosome in Complex with Linker Histone H1.

scientific article published in June 2017

Structure and function of human histone H3.Y nucleosome

scientific article

Structure and function of human histone H3.Y nucleosome

scientific article published on December 2016

Structure of RizA, an L-amino-acid ligase from Bacillus subtilis

scientific article published on 25 August 2015

Structure of human nucleosome containing the testis-specific histone variant TSH2B

scientific article

Structure of the CENP-A nucleosome and its implications for centromeric chromatin architecture ⬇️

scientific article published on January 1, 2011

Structure of the human DNA-repair protein RAD52 containing surface mutations

scientific article

Structures of human nucleosomes containing major histone H3 variants

scientific article

Sufficient amounts of functional HOP2/MND1 complex promote interhomolog DNA repair but are dispensable for intersister DNA repair during meiosis in Arabidopsis

scientific article published on 20 December 2013

Synthetic Posttranslational Modifications: Chemical Catalyst-Driven Regioselective Histone Acylation of Native Chromatin

scientific article published on 23 May 2017

Telomeric repeats act as nucleosome-disfavouring sequences in vivo

scientific article published on 29 October 2013

Testis-Specific Histone Variant H3t Gene Is Essential for Entry into Spermatogenesis

scientific article published in January 2017

The ATR-Chk1 pathway plays a role in the generation of centrosome aberrations induced by Rad51C dysfunction

scientific article published on 29 April 2009

The CENP-A centromere targeting domain facilitates H4K20 monomethylation in the nucleosome by structural polymorphism

scientific article published in Nature Communications

The DnaA homolog of the hyperthermophilic eubacterium Thermotoga maritima forms an open complex with a minimal 149-bp origin region in an ATP-dependent manner

scientific article published on April 2006

The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity

scientific journal article

The Lys313 residue of the human Rad51 protein negatively regulates the strand-exchange activity

scientific article published in January 2008

The N-terminal and C-terminal halves of histone H2A.Z independently function in nucleosome positioning and stability

scientific article published on 05 June 2020

The N-terminal domain of the human Rad51 protein binds DNA: structure and a DNA binding surface as revealed by NMR

scientific article

The actin-related protein hArp8 accumulates on the mitotic chromosomes and functions in chromosome alignment

scientific article

The centromeric nucleosome-like CENP-T-W-S-X complex induces positive supercoils into DNA.

scientific article

The interaction of DiaA and DnaA regulates the replication cycle in E. coli by directly promoting ATP DnaA-specific initiation complexes

scientific article

The mutant RecA proteins, RecAR243Q and RecAK245N, exhibit defective DNA binding in homologous pairing

scientific article published on 01 May 1999

The putative nuclear localization signal of the human RAD52 protein is a potential sumoylation site

scientific article published on 27 February 2010

Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling

scientific article

Two arginine residues suppress the flexibility of nucleosomal DNA in the canonical nucleosome core

scientific article (publication date: 2015)

Unusual nucleosome formation and transcriptome influence by the histone H3mm18 variant

scientific article published on 01 January 2022

Vertebrate Spt2 is a novel nucleolar histone chaperone that assists in ribosomal DNA transcription

scientific article

Vital roles of the second DNA-binding site of Rad52 protein in yeast homologous recombination

scientific article published on 28 March 2011

Xeroderma pigmentosum group C protein interacts with histones: regulation by acetylated states of histone H3.

scientific article published on 24 February 2017

c-ABL tyrosine kinase stabilizes RAD51 chromatin association

scientific article published on 11 March 2009

hCAS/CSE1L regulates RAD51 distribution and focus formation for homologous recombinational repair

scientific article

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