List of works - Wolfgang Hoyer

A D-enantiomeric peptide interferes with hetero-association of amyloid-β oligomers and prion protein

scientific article published in Journal of Biological Chemistry

A kinetic trap is an intrinsic feature in the folding pathway of single-chain Fv fragments

scientific article published in May 2002

A β-hairpin-binding protein for three different disease-related amyloidogenic proteins

scientific article published on 30 December 2014

Alternative conformations of the Tau repeat domain in complex with an engineered binding protein

scientific article published on 25 June 2014

An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils

scientific article published on 21 August 2019

Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy

scientific article published on 21 August 2019

Cellular polyamines promote the aggregation of alpha-synuclein

scientific article published on 14 November 2002

Clustering of human prion protein and α-synuclein oligomers requires the prion protein N-terminus

scientific article published on 09 July 2020

Contact between the β1 and β2 Segments of α-Synuclein that Inhibits Amyloid Formation.

scientific article published on 26 June 2015

Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils

scientific article published on 15 June 2020

DNP-Enhanced MAS NMR: A Tool to Snapshot Conformational Ensembles of α-Synuclein in Different States.

scientific article published in April 2018

Dependence of alpha-synuclein aggregate morphology on solution conditions

scientific article published in September 2002

Double-stranded DNA stimulates the fibrillation of alpha-synuclein in vitro and is associated with the mature fibrils: an electron microscopy study

scientific article published on 01 December 2004

Elucidating the multi-targeted anti-amyloid activity and enhanced islet amyloid polypeptide binding of -wrapins

scientific article published on 21 February 2018

Endo-lysosomal Aβ concentration and pH trigger formation of Aβ oligomers that potently induce Tau missorting

scientific article published on 30 July 2021

Engineered aggregation inhibitor fusion for production of highly amyloidogenic human islet amyloid polypeptide

scientific article

Fibril structure of amyloid-β(1-42) by cryo-electron microscopy

scientific article

Impact of subunit linkages in an engineered homodimeric binding protein to α-synuclein

scientific article

Impact of the acidic C-terminal region comprising amino acids 109-140 on alpha-synuclein aggregation in vitro

scientific article published in December 2004

Interaction of Alzheimer's A beta peptide with an engineered binding protein--thermodynamics and kinetics of coupled folding-binding

scientific article published on 4 March 2008

Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR.

scientific article

NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation.

scientific article published on 22 April 2004

Opposed Effects of Dityrosine Formation in Soluble and Aggregated α-Synuclein on Fibril Growth

scientific article published on 13 September 2017

Origin of metastable oligomers and their effects on amyloid fibril self-assembly

scientific article published on 13 June 2018

QIAD assay for quantitating a compound's efficacy in elimination of toxic Aβ oligomers

scientific article

Rapid self-assembly of alpha-synuclein observed by in situ atomic force microscopy

scientific article

Recombinant amyloid beta-peptide production by coexpression with an affibody ligand

scientific article

Sequestration of a β-hairpin for control of α-synuclein aggregation

scientific article

Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo

scientific article

Single fibril growth kinetics of α-synuclein.

scientific article

Stabilization of a -hairpin in monomeric Alzheimer's amyloid- peptide inhibits amyloid formation

scientific article

Structural Characterization of Fibrils from Recombinant Human Islet Amyloid Polypeptide by Solid-State NMR: The Central FGAILS Segment Is Part of the β-Sheet Core

scientific article

Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation

scientific article published on 3 May 2018

The off-rate of monomers dissociating from amyloid-β protofibrils

scientific article published on 18 November 2013

Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling

scientific article published in Journal of Biological Chemistry

Uncovering the Binding and Specificity of β-Wrapins for Amyloid-β and α-Synuclein

scientific article published on 9 December 2016

α-Synuclein Aggregation Monitored by Thioflavin T Fluorescence Assay.

scientific article published in July 2018

α-Synuclein-derived lipoparticles in the study of α-Synuclein amyloid fibril formation

scientific article published on 28 February 2019

β-Hairpin of Islet Amyloid Polypeptide Bound to an Aggregation Inhibitor

scientific article published on 19 September 2016

List of works by Wolfgang Hoyer

A D-enantiomeric peptide interferes with hetero-association of amyloid-β oligomers and prion protein

A kinetic trap is an intrinsic feature in the folding pathway of single-chain Fv fragments

A β-hairpin-binding protein for three different disease-related amyloidogenic proteins

Alternative conformations of the Tau repeat domain in complex with an engineered binding protein

An engineered monomer binding-protein for α-synuclein efficiently inhibits the proliferation of amyloid fibrils

Atomic structure of PI3-kinase SH3 amyloid fibrils by cryo-electron microscopy

Cellular polyamines promote the aggregation of alpha-synuclein

Clustering of human prion protein and α-synuclein oligomers requires the prion protein N-terminus

Contact between the β1 and β2 Segments of α-Synuclein that Inhibits Amyloid Formation.

Cryo-EM structure of islet amyloid polypeptide fibrils reveals similarities with amyloid-β fibrils

DNP-Enhanced MAS NMR: A Tool to Snapshot Conformational Ensembles of α-Synuclein in Different States.

Dependence of alpha-synuclein aggregate morphology on solution conditions

Double-stranded DNA stimulates the fibrillation of alpha-synuclein in vitro and is associated with the mature fibrils: an electron microscopy study

Elucidating the multi-targeted anti-amyloid activity and enhanced islet amyloid polypeptide binding of -wrapins

Endo-lysosomal Aβ concentration and pH trigger formation of Aβ oligomers that potently induce Tau missorting

Engineered aggregation inhibitor fusion for production of highly amyloidogenic human islet amyloid polypeptide

Fibril structure of amyloid-β(1-42) by cryo-electron microscopy

Impact of subunit linkages in an engineered homodimeric binding protein to α-synuclein

Impact of the acidic C-terminal region comprising amino acids 109-140 on alpha-synuclein aggregation in vitro

Interaction of Alzheimer's A beta peptide with an engineered binding protein--thermodynamics and kinetics of coupled folding-binding

Molecular-level secondary structure, polymorphism, and dynamics of full-length alpha-synuclein fibrils studied by solid-state NMR.

NMR of alpha-synuclein-polyamine complexes elucidates the mechanism and kinetics of induced aggregation.

Opposed Effects of Dityrosine Formation in Soluble and Aggregated α-Synuclein on Fibril Growth

Origin of metastable oligomers and their effects on amyloid fibril self-assembly

QIAD assay for quantitating a compound's efficacy in elimination of toxic Aβ oligomers

Rapid self-assembly of alpha-synuclein observed by in situ atomic force microscopy

Recombinant amyloid beta-peptide production by coexpression with an affibody ligand

Sequestration of a β-hairpin for control of α-synuclein aggregation

Sequestration of the Abeta peptide prevents toxicity and promotes degradation in vivo

Single fibril growth kinetics of α-synuclein.

Stabilization of a -hairpin in monomeric Alzheimer's amyloid- peptide inhibits amyloid formation

Structural Characterization of Fibrils from Recombinant Human Islet Amyloid Polypeptide by Solid-State NMR: The Central FGAILS Segment Is Part of the β-Sheet Core

Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation

The off-rate of monomers dissociating from amyloid-β protofibrils

Transcriptome-wide analysis uncovers the targets of the RNA-binding protein MSI2 and effects of MSI2's RNA-binding activity on IL-6 signaling

Uncovering the Binding and Specificity of β-Wrapins for Amyloid-β and α-Synuclein

α-Synuclein Aggregation Monitored by Thioflavin T Fluorescence Assay.

α-Synuclein-derived lipoparticles in the study of α-Synuclein amyloid fibril formation

β-Hairpin of Islet Amyloid Polypeptide Bound to an Aggregation Inhibitor