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List of works by Frits van Rhee

3195 Genomic Analysis of Primary Plasma Cell Leukemia reveals Complex Cytogenetic Alterations and High Risk Mutational Patterns

A Phase I, Open-Label Study of Siltuximab, an Anti–IL-6 Monoclonal Antibody, in Patients with B-cell Non-Hodgkin Lymphoma, Multiple Myeloma, or Castleman Disease ⬇️

scientific article published on May 9, 2013

A compound T60A and V122I heterozygosity in the transthyretin gene causing early onset severe cardiac amyloidosis

article

A meta-analysis of genome-wide association studies of multiple myeloma among men and women of African ancestry

scientific article published on 01 January 2020

A phase 1, multicenter, open-label, dose escalation study of elotuzumab in patients with advanced multiple myeloma ⬇️

scientific article published on December 19, 2011

A phase 2, open-label, multicenter study of the long-term safety of siltuximab (an anti-interleukin-6 monoclonal antibody) in patients with multicentric Castleman disease

scientific article published on 3 August 2015

A validated gene expression model of high-risk multiple myeloma is defined by deregulated expression of genes mapping to chromosome 1.

scientific article published on 14 November 2006

ACCELERATE: A Patient-Powered Natural History Study Design Enabling Clinical and Therapeutic Discoveries in a Rare Disorder

scientific article published on 22 December 2020

Accelerated single cell seeding in relapsed multiple myeloma

scientific article published on 17 July 2020

Adoptive immunotherapy for relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: equal efficacy of lymphocytes from sibling and matched unrelated donors

scientific article published on 01 May 1998

Adoptive transfer of Ag-specific T cells to prevent CMV disease after allogeneic stem-cell transplantation

scientific article

Adverse Metaphase Cytogenetics Can Be Overcome by Adding Bortezomib and Thalidomide to Fractionated Melphalan Transplants

scientific article published on 3 November 2016

Allogeneic bone marrow transplantation from partially mismatched related donors as therapy for primary induction failure acute myeloid leukemia

scientific article published on 01 March 2001

Allogeneic transplantation from HLA-matched sibling or partially HLA-mismatched related donors for primary refractory acute leukemia

scientific article published on 01 February 2002

Allografting or autografting for myeloma

scientific article published on 01 June 2007

An acquired high-risk chromosome instability phenotype in multiple myeloma: Jumping 1q Syndrome

scientific article published on 09 August 2019

Analysis of Inflammatory and Anemia-Related Biomarkers in a Randomized, Double-Blind, Placebo-Controlled Study of Siltuximab (Anti-IL6 Monoclonal Antibody) in Patients With Multicentric Castleman Disease

scientific article published on 29 June 2015

Aplasia after donor lymphocyte infusion (DLI) for CML in relapse after sex-mismatched BMT: recovery of donor-type haemopoiesis predicted by non-isotopic in situ hybridization (ISH)

scientific article published on 01 October 1994

Assessment of Total Lesion Glycolysis by 18F FDG PET/CT Significantly Improves Prognostic Value of GEP and ISS in Myeloma

scientific article published on 3 October 2016

Atrial Fibrillation in Hematologic Malignancies, Especially After Autologous Hematopoietic Stem Cell Transplantation: Review of Risk Factors, Current Management, and Future Directions

scientific article

BRAF and DIS3 Mutations Associate with Adverse Outcome in a Long-term Follow-up of Patients with Multiple Myeloma

scientific article published on 27 January 2020

Benefit of complete response in multiple myeloma limited to high-risk subgroup identified by gene expression profiling

scientific article published in December 2007

Bi-allelic inactivation is more prevalent at relapse in multiple myeloma, identifying RB1 as an independent prognostic marker

scientific article published on 24 February 2017

Bone marrow microenvironments that contribute to patient outcomes in newly diagnosed multiple myeloma: A cohort study of patients in the Total Therapy clinical trials

scientific article published on 04 November 2020

Bone marrow transplantation for chronic myeloid leukemia with volunteer unrelated donors using ex vivo or in vivo T-cell depletion: major prognostic impact of HLA class I identity between donor and recipient

scientific article

Bortezomib down-regulates the cell-surface expression of HLA class I and enhances natural killer cell-mediated lysis of myeloma

scientific article

CD4(+) bias in T cells cloned from a CML patient with active graft versus leukemia effect

scientific article published on January 2002

CS1, a potential new therapeutic antibody target for the treatment of multiple myeloma

scientific article published on May 2008

CYR61/CCN1 overexpression in the myeloma microenvironment is associated with superior survival and reduced bone disease

scientific article

Candida glabrata and Candida krusei fungemia after high-risk allogeneic marrow transplantation: no adverse effect of low-dose fluconazole prophylaxis on incidence and outcome ⬇️

scientific article published on November 1, 2001

Cardiac complications in relapsed and refractory multiple myeloma patients treated with carfilzomib

scientific article published on 16 January 2015

Castleman Disease

scientific article published on 01 February 2018

Castleman disease in the 21st century: an update on diagnosis, assessment, and therapy

scientific article published on July 1, 2010

Characterization of the molecular mechanism of the bone-anabolic activity of carfilzomib in multiple myeloma

scientific article

Clinical characteristics and prognostic factors in multiple myeloma patients with light chain deposition disease.

scientific article published on 6 April 2017

Clinical efficacy of sequencing CD38 targeting monoclonal antibodies in relapsed refractory multiple myeloma: A multi‐institutional experience

scientific article published in 2022

Clinical grade purification and expansion of natural killer cells

scientific article

Clinical value of molecular subtyping multiple myeloma using gene expression profiling

scientific article published on 3 November 2015

Clinical-grade myeloma Ag pre-loaded DC vaccines retain potency after cryopreservation

scientific article

Clonal cytogenetic changes and myeloma relapse after reduced intensity conditioning allogeneic transplantation

scientific article

Clonal selection and double-hit events involving tumor suppressor genes underlie relapse in myeloma.

scientific article published on 11 August 2016

Combination of flow cytometry and functional imaging for monitoring of residual disease in myeloma.

scientific article published on 20 December 2018

Combinatorial efficacy of anti-CS1 monoclonal antibody elotuzumab (HuLuc63) and bortezomib against multiple myeloma

scientific article published on September 2009

Comparison of single-dose and escalating-dose regimens of donor lymphocyte infusion for relapse after allografting for chronic myeloid leukemia

scientific article published on 01 January 2000

Complete remission in multiple myeloma examined as time-dependent variable in terms of both onset and duration in Total Therapy protocols

scientific article published on 10 June 2009

Complete response in myeloma extends survival without, but not with history of prior monoclonal gammopathy of undetermined significance or smouldering disease

scientific article published on 08 December 2006

Completion of premaintenance phases in total therapies 2 and 3 improves clinical outcomes in multiple myeloma: an important variable to be considered in clinical trial designs

scientific article published in June 2008

Con: allogeneic transplantation in multiple myeloma

scientific article published on 01 May 2006

Curing myeloma at last: defining criteria and providing the evidence

scientific article

Cytogenetic abnormalities in multiple myeloma: poor prognosis linked to concomitant detection in random and focal lesion bone marrow samples and associated with high-risk gene expression profile

scientific article published on 29 March 2009

Cytogenetically defined myelodysplasia after melphalan-based autotransplantation for multiple myeloma linked to poor hematopoietic stem-cell mobilization: the Arkansas experience in more than 3,000 patients treated since 1989.

scientific article

Cytotoxic T lymphocyte precursor frequency analyses in bone marrow transplantation with volunteer unrelated donors. Value in donor selection

scientific article published on 01 May 1995

DTPACE: an effective, novel combination chemotherapy with thalidomide for previously treated patients with myeloma

scientific article

Daratumumab for POEMS Syndrome

scientific article published on 01 April 2018

Daratumumab in high-risk relapsed/refractory multiple myeloma patients: adverse effect of chromosome 1q21 gain/amplification and GEP70 status on outcome

scientific article published on 09 December 2019

Deep vein thrombosis in patients with multiple myeloma treated with thalidomide and chemotherapy: effects of prophylactic and therapeutic anticoagulation

scientific article

Detection of residual leukaemia more than 10 years after allogeneic bone marrow transplantation for chronic myelogenous leukaemia

scientific article published on 01 October 1994

Detection of the BCR-ABL gene by reverse transcription/polymerase chain reaction and fluorescence in situ hybridization in a patient with Philadelphia chromosome negative acute lymphoblastic leukaemia

scientific article published on 01 May 1995

Dialysis-dependent renal failure in patients with myeloma can be reversed by high-dose myeloablative therapy and autotransplant

scientific article published in April 2004

Distinct T cell populations distinguish chronic myeloid leukaemia cells from lymphocytes in the same individual: a model for separating GVHD from GVL reactions

scientific article published on 01 October 1994

Donor leukocyte transfusions for leukemic relapse ⬇️

scientific article published on November 1, 1995

Dose-dense and less dose-intense Total Therapy 5 for gene expression profiling-defined high-risk multiple myeloma

scientific article published on 29 July 2016

Dose-dense and less dose-intense total therapy 5 for gene expression profiling-defined high-risk multiple myeloma.

scientific article published on 16 September 2016

Efficient lysis of epithelial ovarian cancer cells by MAGE-A3-induced cytotoxic T lymphocytes using rAAV-6 capsid mutant vector

scientific article published on 6 January 2014

Eight-year median survival in multiple myeloma after total therapy 2: roles of thalidomide and consolidation chemotherapy in the context of total therapy 1.

scientific article published on 26 March 2008

Engineering more efficacious antibody therapy for myeloma

scientific article published on May 2014

Epigenetic modulation of MAGE-A3 antigen expression in multiple myeloma following treatment with the demethylation agent 5-azacitidine and the histone deacetlyase inhibitor MGCD0103 ⬇️

scientific article published on December 20, 2010

Epstein-Barr virus-associated B cell lymphoproliferative disorder following mismatched related T cell-depleted bone marrow transplantation

scientific article published in December 2001

Eruptive cherry hemangiomatosis associated with multicentric Castleman disease: a case report and diagnostic clue.

scientific article published in February 2013

Estimating leukemia-free survival after allografting for chronic myeloid leukemia: a new method that takes into account patients who relapse and are restored to complete remission

scientific article published on 01 July 2000

Evidence of an epigenetic origin for high-risk 1q21 copy number aberrations in multiple myeloma

scientific article published on 5 May 2015

Ex vivo-expanded natural killer cells demonstrate robust proliferation in vivo in high-risk relapsed multiple myeloma patients

scientific article

Extensive Remineralization of Large Pelvic Lytic Lesions Following Total Therapy Treatment in Patients With Multiple Myeloma.

scientific article published on 27 February 2017

Extramedullary disease portends poor prognosis in multiple myeloma and is over-represented in high-risk disease even in the era of novel agents

scientific article

F18-fluorodeoxyglucose positron emission tomography in the context of other imaging techniques and prognostic factors in multiple myeloma

scientific article published on 14 May 2009

First thalidomide clinical trial in multiple myeloma: a decade

scientific article published on 23 May 2008

Five gene probes carry most of the discriminatory power of the 70-gene risk model in multiple myeloma

scientific article published on 31 July 2014

Flow cytometry defined cytoplasmic immunoglobulin index is a major prognostic factor for progression of asymptomatic monoclonal gammopathies to multiple myeloma (subset analysis of SWOG S0120).

scientific article published on 25 March 2016

Four genes predict high risk of progression from smoldering to symptomatic multiple myeloma (SWOG S0120).

scientific article published on 28 May 2015

Frequent gain of chromosome band 1q21 in plasma-cell dyscrasias detected by fluorescence in situ hybridization: incidence increases from MGUS to relapsed myeloma and is related to prognosis and disease progression following tandem stem-cell transpla

scientific article published on 16 May 2006

Fulminant onset of acute leukemia from normal hematopoiesis within 3 months of follow up for multiple myeloma treated with total therapy protocols

scientific article published on 13 February 2015

Functional dissection of inherited non-coding variation influencing multiple myeloma risk

scientific article

Ganciclovir and the prevention of CMV disease after allogeneic BMT: policy at the Hammersmith Hospital

scientific article published on 01 February 1994

Gene expression profiling of plasma cells at myeloma relapse from tandem transplantation trial Total Therapy 2 predicts subsequent survival

scientific article published on 23 April 2009

Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis

scientific article published on 5 October 2006

Genomic analysis of primary plasma cell leukemia reveals complex structural alterations and high-risk mutational patterns

scientific article published on 19 June 2020

Global gene expression profiling of multiple myeloma, monoclonal gammopathy of undetermined significance, and normal bone marrow plasma cells

scientific article

Graft-versus-leukemia effect of donor lymphocyte transfusions in marrow grafted patients ⬇️

scientific article published on 01 September 1995

HHV-8-negative, idiopathic multicentric Castleman disease: novel insights into biology, pathogenesis, and therapy

scientific article

Haematological cancer: Optimizing the treatment of multiple myeloma

scientific article published on 28 October 2014

Haploidentical vs autologous hematopoietic stem cell transplantation in patients with acute leukemia beyond first remission ⬇️

scientific article published on 01 May 2003

High incidence of adeno- and polyomavirus-induced hemorrhagic cystitis in bone marrow allotransplantation for hematological malignancy following T cell depletion and cyclosporine.

scientific article

High serum-free light chain levels and their rapid reduction in response to therapy define an aggressive multiple myeloma subtype with poor prognosis

scientific article

High-Level Expression of Cancer/Testis Antigen NY-ESO-1 and Human Granulocyte-Macrophage Colony-Stimulating Factor in Dendritic Cells with a Bicistronic Retroviral Vector ⬇️

scientific article published on September 20, 2003

High-dose melphalan-based autotransplants for multiple myeloma: the Arkansas experience since 1989 in 3077 patients

scientific article published on April 2008

High-risk myeloma is associated with global elevation of miRNAs and overexpression of EIF2C2/AGO2.

scientific article

Highly activated and expanded natural killer cells for multiple myeloma immunotherapy ⬇️

scientific article published on March 14, 2012

Homozygosity for the V122I mutation in transthyretin is associated with earlier onset of cardiac amyloidosis in the African American population in the seventh decade of life.

scientific article published on 30 October 2013

Human Placenta-Derived Adherent Cells Prevent Bone loss, Stimulate Bone formation, and Suppress Growth of Multiple Myeloma in Bone ⬇️

scientific article published on February 1, 2011

Human gammadelta(+) T lymphocytes have in vitro graft vs leukemia activity in the absence of an allogeneic response

scientific article published on 01 March 2001

Hyperhaploidy is a novel high-risk cytogenetic subgroup in multiple myeloma.

scientific article

Identifying and targeting pathogenic PI3K/AKT/mTOR signaling in IL-6-blockade-refractory idiopathic multicentric Castleman disease

scientific article published on 13 August 2019

Idiopathic multicentric Castleman's disease: a systematic literature review

scientific article published on 17 March 2016

Idiotype vaccination strategies in myeloma: how to overcome a dysfunctional immune system

scientific article published on March 2007

Immunization with a recombinant MAGE-A3 protein after high-dose therapy for myeloma

scientific article published on 01 November 2007

Immunologic approaches for the treatment of multiple myeloma

scientific article

Improved outcome of allogeneic transplantation in high-risk multiple myeloma patients after nonmyeloablative conditioning

scientific article published on 01 March 2002

In multiple myeloma, 14q32 translocations are nonrandom chromosomal fusions driving high expression levels of the respective partner genes

scientific article

In vitro generation of Epstein-Barr virus-specific cytotoxic T cells in patients receiving haplo-identical allogeneic stem cell transplantation

scientific article

Incorporating bortezomib into upfront treatment for multiple myeloma: early results of total therapy 3

scientific article published on 01 July 2007

Infectious and immunological sequelae of daratumumab in multiple myeloma

scientific article published on 05 July 2018

Infusion of haplo-identical killer immunoglobulin-like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation

scientific article published on 16 October 2008

Inhibiting MEK in MAPK pathway-activated myeloma

scientific article published on 31 July 2015

Insufficient evidence exists to use histopathologic subtype to guide treatment of idiopathic multicentric Castleman disease

scientific article published on 07 September 2020

Interleukin-6 receptor polymorphism is prevalent in HIV-negative Castleman Disease and is associated with increased soluble interleukin-6 receptor levels

scientific article

International evidence-based consensus diagnostic and treatment guidelines for unicentric Castleman disease

scientific article published on 01 December 2020

International staging system and metaphase cytogenetic abnormalities in the era of gene expression profiling data in multiple myeloma treated with total therapy 2 and 3 protocols ⬇️

scientific article published on October 13, 2010

International, evidence-based consensus diagnostic criteria for HHV-8-negative/idiopathic multicentric Castleman disease

scientific article

International, evidence-based consensus treatment guidelines for idiopathic multicentric Castleman disease

scientific article published on 04 September 2018

Iron overload is a major risk factor for severe infection after autologous stem cell transplantation: a study of 367 myeloma patients

scientific article published in May 2006

Is double autologous stem-cell transplantation appropriate for new multiple myeloma patients?

scientific article published on 6 November 2007

Isolation and expansion of cytomegalovirus-specific cytotoxic T lymphocytes to clinical scale from a single blood draw using dendritic cells and HLA-tetramers

scientific article published in August 2001

Jumping translocations of 1q12 in multiple myeloma: a novel mechanism for deletion of 17p in cytogenetically defined high-risk disease

scientific article published on 04 February 2014

Kinase domain activation through gene rearrangement in multiple myeloma.

scientific article published on 23 March 2018

Kinetics of increasing BCR-ABL transcript numbers in chronic myeloid leukemia patients who relapse after bone marrow transplantation

scientific article published on 01 May 1996

Lack of Spleen Signal on Diffusion Weighted MRI is associated with High Tumor Burden and Poor Prognosis in Multiple Myeloma: A Link to Extramedullary Hematopoiesis?

scientific article published on 09 July 2019

Light-chain MGUS: implications for clinical practice

scientific article published on 01 May 2010

Long-term follow-up of autotransplantation trials for multiple myeloma: update of protocols conducted by the intergroupe francophone du myelome, southwest oncology group, and university of arkansas for medical sciences

scientific article

Long-term outcome results of the first tandem autotransplant trial for multiple myeloma

scientific article published on 25 August 2006

Long-term outcomes after autologous stem cell transplantation for multiple myeloma

scientific article published on 01 January 2020

Long-term results after allogeneic bone marrow transplantation for chronic myelogenous leukemia in chronic phase: a report from the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation

scientific article published on 01 October 1997

Long-term safety of siltuximab in patients with idiopathic multicentric Castleman disease: a prespecified, open-label, extension analysis of two trials

scientific article published on 03 February 2020

MAF protein mediates innate resistance to proteasome inhibition therapy in multiple myeloma

scientific article published on 28 October 2016

MAFb protein confers intrinsic resistance to proteasome inhibitors in multiple myeloma.

scientific article published on 6 July 2018

Magnetic resonance imaging in multiple myeloma: diagnostic and clinical implications

scientific article published on 12 February 2007

Making progress in treating multiple myeloma with total therapies: issue of complete remission and more

scientific article published on 28 February 2008

Mesenchymal stem cells gene signature in high-risk myeloma bone marrow linked to suppression of distinct IGFBP2-expressing small adipocytes

article

Metronomic therapy is an effective salvage treatment for heavily pre-treated relapsed/refractory multiple myeloma ⬇️

scientific article published on May 28, 2013

Mobilization of peripheral blood stem cells in myeloma with either pegfilgrastim or filgrastim following chemotherapy

scientific article published on 25 August 2008

Molecular studies in patients with chronic myeloid leukaemia in remission 5 years after allogeneic stem cell transplant define the risk of subsequent relapse

article

Monitoring Treatment Response and Disease Progression in Myeloma with Circulating Cell-Free DNA

scientific article published on 26 October 2020

Monoclonal antibody therapy in multiple myeloma: where do we stand and where are we going?

scientific article published on 17 February 2016

Myeloid transformation of plasma cell myeloma: molecular evidence of clonal evolution revealed by next generation sequencing

scientific article published on 20 February 2018

NAMPT/PBEF1 enzymatic activity is indispensable for myeloma cell growth and osteoclast activity ⬇️

scientific article published on February 19, 2013

NY-ESO-1 immunotherapy for multiple myeloma

scientific article published on October 2006

NY-ESO-1 is highly expressed in poor-prognosis multiple myeloma and induces spontaneous humoral and cellular immune responses

scientific article

Newly diagnosed and previously treated multicentric Castleman disease respond equally to siltuximab

scientific article published on 31 October 2020

Non-myeloablative allogeneic transplantation ('microallograft') for refractory myeloma after two preceding autografts: feasibility and efficacy in a patient with active aspergillosis

scientific article published on 01 December 2000

Oncolytic Measles Virotherapy and Opposition to Measles Vaccination

scientific article published on 22 June 2019

Optimizing dendritic cell-based immunotherapy in multiple myeloma: intranodal injections of idiotype-pulsed CD40 ligand-matured vaccines led to induction of type-1 and cytotoxic T-cell immune responses in patients

scientific article

Oral mucositis in myeloma patients undergoing melphalan-based autologous stem cell transplantation: incidence, risk factors and a severity predictive model

scientific article published on 01 October 2006

Partially mismatched related donor bone marrow transplantation as salvage for patients with AML who failed autologous stem cell transplant ⬇️

scientific article published on 01 December 2001

Patient-reported Outcomes for Multicentric Castleman's Disease in a Randomized, Placebo-controlled Study of Siltuximab

scientific article

Patterns of central nervous system involvement in relapsed and refractory multiple myeloma

scientific article

Pharmacogenomics of bortezomib test-dosing identifies hyperexpression of proteasome genes, especially PSMD4, as novel high-risk feature in myeloma treated with Total Therapy 3 ⬇️

scientific article published on May 31, 2011

Pharmacologic doses of granulocyte colony-stimulating factor affect cytokine production by lymphocytes in vitro and in vivo

scientific article published on 01 April 2000

Phase II study of pomalidomide in high-risk relapsed and refractory multiple myeloma

scientific article published on 25 August 2014

Plasma proteomics identifies a 'chemokine storm' in idiopathic multicentric Castleman disease

scientific article published on 16 May 2018

Poor overall survival in hyperhaploid multiple myeloma is defined by double-hit bi-allelic inactivation of

scientific article published on 22 January 2019

Predicting long-term survival in multiple myeloma patients following autotransplants

scientific article

Predictors of response to anti-IL6 monoclonal antibody therapy (siltuximab) in idiopathic multicentric Castleman disease: secondary analyses of phase II clinical trial data

scientific article published on 11 September 2018

Primary plasma cell leukemia: clinical and laboratory presentation, gene-expression profiling and clinical outcome with Total Therapy protocols ⬇️

scientific article published on April 17, 2012

Profile of elotuzumab and its potential in the treatment of multiple myeloma

scientific article published on June 2014

Prognostic factors in allogeneic transplantation for patients with high-risk multiple myeloma after reduced intensity conditioning

scientific article published on 01 January 2003

Prognostic implications of serial 18-fluoro-deoxyglucose emission tomography in multiple myeloma treated with total therapy 3 ⬇️

scientific article published on January 10, 2013

Protein transduction of dendritic cells for NY-ESO-1-based immunotherapy of myeloma

scientific article published in November 2005

Quantification of residual disease in Philadelphia-positive acute lymphoblastic leukemia: comparison of blood and bone marrow.

scientific article

Quantification of residual disease in chronic myelogenous leukemia patients on interferon-alpha therapy by competitive polymerase chain reaction

scientific article published on 01 February 1996

Race-dependent differences in risk, genomics and Epstein-Barr virus exposure in monoclonal gammopathies: Results of SWOG S0120

scientific article published on 18 August 2020

Recovery from neutropenia can be predicted by the immature reticulocyte fraction several days before neutrophil recovery in autologous stem cell transplant recipients

scientific article published in February 2006

Reiterative survival analyses of total therapy 2 for multiple myeloma elucidate follow-up time dependency of prognostic variables and treatment arms

scientific article

Relapse of chronic myeloid leukemia after allogeneic bone marrow transplant: the case for giving donor leukocyte transfusions before the onset of hematologic relapse

scientific article published on 01 June 1994

Renal insufficiency retains adverse prognostic implications despite renal function improvement following Total Therapy for newly diagnosed multiple myeloma.

scientific article published on 2 February 2012

Response: Top tertile SFLC reduction indeed is an independent feature of myeloma aggressiveness.

scientific article published in February 2008

Risk factors for MDS and acute leukemia following total therapy 2 and 3 for multiple myeloma ⬇️

scientific article published on April 19, 2013

Role of Bruton's tyrosine kinase (BTK) in growth and metastasis of INA6 myeloma cells.

scientific article

Role of Bruton's tyrosine kinase in myeloma cell migration and induction of bone disease ⬇️

scientific article published on March 28, 2013

Role of quantitative human cytomegalovirus PCR in predicting antiviral treatment response among high-risk hematopoietic stem-cell transplant recipients

scientific article published on 01 February 2004

Second malignancies in total therapy 2 and 3 for newly diagnosed multiple myeloma: influence of thalidomide and lenalidomide during maintenance ⬇️

scientific article published on June 6, 2012

Separating graft-versus-tumor from graft-versus-host reactions

scientific article

Seven-year median time to progression with thalidomide for smoldering myeloma: partial response identifies subset requiring earlier salvage therapy for symptomatic disease

scientific article

Siltuximab for multicentric Castleman disease

scientific article published on 9 August 2014

Siltuximab for multicentric Castleman's disease: a randomised, double-blind, placebo-controlled trial

scientific article

Siltuximab, a novel anti-interleukin-6 monoclonal antibody, for Castleman's disease

scientific article

Spatial genomic heterogeneity in multiple myeloma revealed by multi-region sequencing

scientific article published on 16 August 2017

Standard and novel imaging methods for multiple myeloma: correlates with prognostic laboratory variables including gene expression profiling data ⬇️

scientific article published on June 24, 2012

Storming the Castle with TCP

scientific article published on 01 April 2019

Superior 12-year survival after at least 4-year continuous remission with tandem transplantations for multiple myeloma

scientific article published on 01 May 2006

Superior results of Total Therapy 3 (2003-33) in gene expression profiling-defined low-risk multiple myeloma confirmed in subsequent trial 2006-66 with VRD maintenance

scientific article

Suppression of abnormal karyotype predicts superior survival in multiple myeloma

scientific article published on 17 January 2008

Survival after relapse following tandem autotransplants in multiple myeloma patients: the University of Arkansas total therapy I experience ⬇️

scientific article published on 01 November 2003

Sustained complete remissions in multiple myeloma linked to bortezomib in total therapy 3: comparison with total therapy 2.

scientific article published on March 2008

TEL-AML1 fusion in acute lymphoblastic leukaemia of adults

article

TP53 deletion is not an adverse feature in multiple myeloma treated with total therapy 3

scientific article published on 21 August 2009

Testing standard and genetic parameters in 220 patients with multiple myeloma with complete data sets: superiority of molecular genetics

scientific article

Thalidomide and deep vein thrombosis in multiple myeloma: risk factors and effect on survival

scientific article published in June 2003

Thalidomide and hematopoietic-cell transplantation for multiple myeloma

scientific article published in March 2006

Thalidomide arm of Total Therapy 2 improves complete remission duration and survival in myeloma patients with metaphase cytogenetic abnormalities

scientific article published on 20 May 2008

Thalidomide in total therapy 2 overcomes inferior prognosis of myeloma with low expression of the glucocorticoid receptor gene NR3C1

scientific article published on August 2012

The Arkansas approach to therapy of patients with multiple myeloma

scientific article published on December 2007

The Pattern of Mesenchymal Stem Cell Expression Is an Independent Marker of Outcome in Multiple Myeloma

scientific article published on 21 March 2018

The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of hematologic malignancies: multiple myeloma, lymphoma, and acute leukemia

scientific article published on 20 December 2016

The flow cytometry-defined light chain cytoplasmic immunoglobulin index and an associated 12-gene expression signature are independent prognostic factors in multiple myeloma

scientific article

The functional epigenetic landscape of aberrant gene expression in molecular subgroups of newly diagnosed multiple myeloma

scientific article published on 06 August 2020

The future of autologous stem cell transplantation in myeloma

scientific article

The level of deletion 17p and bi-allelic inactivation of TP53 has a significant impact on clinical outcome in multiple myeloma.

scientific article published on 26 May 2017

The molecular classification of multiple myeloma

scientific article

The presence of large focal lesions is a strong independent prognostic factor in multiple myeloma

scientific article published on 5 July 2018

The prognostic value of the depth of response in multiple myeloma depends on the time of assessment, risk status and molecular subtype

scientific article published on 18 May 2017

The rate and kinetics of molecular response to donor leucocyte transfusions in chronic myeloid leukaemia patients treated for relapse after allogeneic bone marrow transplantation

article

Total Therapy 3 for multiple myeloma: prognostic implications of cumulative dosing and premature discontinuation of VTD maintenance components, bortezomib, thalidomide, and dexamethasone, relevant to all phases of therapy

scientific article

Total therapy 2 without thalidomide in comparison with total therapy 1: role of intensified induction and posttransplantation consolidation therapies

scientific article published in December 2005

Transplantation as salvage therapy for high-risk patients with myeloma in relapse

scientific article published in December 2002

Transplantation for Multiple Myeloma

scientific article

Treatment advances in multiple myeloma

scientific article published on April 2004

Treatment of Idiopathic Castleman Disease

scientific article published in February 2018

Treatment to suppression of focal lesions on positron emission tomography-computed tomography is a therapeutic goal in newly diagnosed multiple myeloma

scientific article published in June 2018

Turning up the heat on myeloma

scientific article published on 01 October 2009

Type I IFN response associated with mTOR activation in the TAFRO subtype of idiopathic multicentric Castleman disease

scientific article published on 07 May 2020

VTD combination therapy with bortezomib-thalidomide-dexamethasone is highly effective in advanced and refractory multiple myeloma

scientific article published on 24 April 2008

Variable numbers of BCR-ABL transcripts persist in CML patients who achieve complete cytogenetic remission with interferon-α

scientific article published on 01 September 1995

Virome capture sequencing does not identify active viral infection in unicentric and idiopathic multicentric Castleman disease

scientific article published on 26 June 2019

p190 BCR-ABL mRNA is expressed at low levels in p210-positive chronic myeloid and acute lymphoblastic leukemias

scientific article published on 01 June 1996

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