List of works - Cenk Ayata

Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney

scientific article

Abnormal synaptic Ca(2+) homeostasis and morphology in cortical neurons of familial hemiplegic migraine type 1 mutant mice

scientific article

Achieving normothermia in patients with febrile subarachnoid hemorrhage: feasibility and safety of a novel intravascular cooling catheter

scientific article

Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy

scientific article

Age-related decline in oligodendrogenesis retards white matter repair in mice

scientific article published on 23 July 2013

Androgenic suppression of spreading depression in familial hemiplegic migraine type 1 mutant mice

scientific article published on October 2009

Anesthesia in Experimental Stroke Research

scientific article published on 17 August 2016

CADASIL: experimental insights from animal models ⬇️

scientific article published on October 1, 2010

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome mutations increase susceptibility to spreading depression

scientific article

Cerebrovascular lesions induce transient β-amyloid deposition

scientific article published on 26 November 2011

Comparative Effectiveness of Calabadion and Sugammadex to Reverse Non-depolarizing Neuromuscular-blocking Agents

scientific article published on 29 September 2015

Concussive injury before or after controlled cortical impact exacerbates histopathology and functional outcome in a mixed traumatic brain injury model in mice

scientific article published on 20 February 2013

Cortical spreading depression and migraine

scientific article published on May 2010

Cortical spreading depression as a target for anti-migraine agents

scientific article published on 23 July 2013

Cortical spreading depression impairs oxygen delivery and metabolism in mice

scientific article

Cortical spreading depression triggers migraine attack: pro.

scientific article published on April 2010

Decreased microvascular cerebral blood flow assessed by diffuse correlation spectroscopy after repetitive concussions in mice

scientific article

Emerging concepts in sporadic cerebral amyloid angiopathy

scientific article published on 13 March 2017

Endothelial dysfunction abrogates the efficacy of normobaric hyperoxia in stroke

scientific article

Endovascular thrombectomy and post-procedural headache

scientific article published on 28 January 2017

Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice

scientific article

Etomidate and Ketamine: Residual Motor and Adrenal Dysfunction that Persist beyond Recovery from Loss of Righting Reflex in Rats

scientific article published on 29 December 2014

Fingolimod exerts neuroprotective effects in a mouse model of intracerebral hemorrhage

scientific article published on 3 February 2014

Gabapentin reduces infarct volume but does not suppress peri-infarct depolarizations

scientific article

Gabapentin suppresses cortical spreading depression susceptibility

scientific article published on 30 June 2010

Genetic Animal Models of Cerebral Vasculopathies ⬇️

scientific article published on January 1, 2012

Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1.

scientific article

Glucose Modulation of Spreading Depression Susceptibility ⬇️

scientific article published on September 12, 2012

High-flow oxygen therapy for treatment of acute migraine: A randomized crossover trial

scientific article published on 20 May 2016

High-resolution in vivo optical imaging of stroke injury and repair

scientific article

Hyperlipidemia Disrupts Cerebrovascular Reflexes and Worsens Ischemic Perfusion Defect ⬇️

scientific article published on March 13, 2013

Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease

scientific article

Imaging PEG-like nanoprobes in tumor, transient ischemia, and inflammatory disease models

scientific article published on 14 May 2015

Increased glucose availability does not restore prolonged spreading depression durations in hypotensive rats without brain injury ⬇️

scientific article published on August 19, 2012

Intensive care management of specific stroke treatment

scientific article

Ischaemic brain oedema

scientific article

Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue

scientific article

Laser speckle flowmetry for the study of cerebrovascular physiology in normal and ischemic mouse cortex

scientific article

Lasting pure-motor deficits after focal posterior internal capsule white-matter infarcts in rats

scientific article

Late-onset thermal hypersensitivity after focal ischemic thalamic infarcts as a model for central post-stroke pain in rats

scientific article

Linking Notch signaling to ischemic stroke

scholarly article

Micro-heterogeneity of flow in a mouse model of chronic cerebral hypoperfusion revealed by longitudinal Doppler optical coherence tomography and angiography

scientific article

Microemboli may link spreading depression, migraine aura, and patent foramen ovale

scientific article

Migraine and stroke: in search of shared mechanisms

scientific article published on 16 September 2014

Migraine mutations impair hippocampal learning despite enhanced long-term potentiation

scientific article

Migraine mutations increase stroke vulnerability by facilitating ischemic depolarizations

scientific article published on 5 December 2011

Migraine pathophysiology: lessons from mouse models and human genetics

scientific article

Migraine prophylaxis, ischemic depolarizations, and stroke outcomes in mice

scientific article

Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia

scientific article

Multiparametric, longitudinal optical coherence tomography imaging reveals acute injury and chronic recovery in experimental ischemic stroke

scientific article

Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits peri-infarct depolarizations in experimental focal ischaemia

scientific article

Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis

scientific article

Oligodendrocyte precursors induce early blood-brain barrier opening after white matter injury ⬇️

scientific article published on January 2, 2013

Optical coherence tomography for the quantitative study of cerebrovascular physiology ⬇️

scientific article published on March 2, 2011

Pearls and pitfalls in experimental models of spreading depression ⬇️

scientific article published on June 1, 2013

Perfusion pressure-dependent recovery of cortical spreading depression is independent of tissue oxygenation over a wide physiologic range

scientific article

Pharmacological targeting of spreading depression in migraine ⬇️

scientific article published on March 1, 2012

Phase III Preclinical Trials in Translational Stroke Research: Community Response on Framework and Guidelines

scientific article published on 14 June 2016

Preclinical phase III trials in translational stroke research: call for collective design of framework and guidelines

scientific article published on 09 January 2014

Pronounced hypoperfusion during spreading depression in mouse cortex

scientific article published in October 2004

Quantitative Imaging of Cerebral Blood Flow Velocity and Intracellular Motility using Dynamic Light Scattering–Optical Coherence Tomography ⬇️

scientific article published on February 13, 2013

Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms

scientific article

Rho-kinase inhibition improves ischemic perfusion deficit in hyperlipidemic mice

scientific article

Selective ROCK2 inhibition in focal cerebral ischemia

scientific article

Sensitivity to acute cerebral ischemic injury in migraineurs: A retrospective case-control study

scientific article

Simultaneous imaging of cerebral partial pressure of oxygen and blood flow during functional activation and cortical spreading depression

scientific article

Simultaneous multispectral reflectance imaging and laser speckle flowmetry of cerebral blood flow and oxygen metabolism in focal cerebral ischemia

scientific article

Spreading Depolarizations: A Therapeutic Target Against Delayed Cerebral Ischemia After Subarachnoid Hemorrhage

scientific article published on June 2016

Spreading Depression and Neurovascular Coupling ⬇️

scientific article published on June 1, 2013

Spreading Depression in Primary and Secondary Headache Disorders

scientific article published on July 2016

Spreading Depression, Spreading Depolarizations, and the Cerebral Vasculature

scientific article

Spreading depression and the clinical correlates of migraine

scientific article published on January 2013

Subarachnoid hemorrhage, spreading depolarizations and impaired neurovascular coupling

scientific article published on 13 March 2013

Supply-demand mismatch transients in susceptible peri-infarct hot zones explain the origins of spreading injury depolarizations

scientific article

Suppression of cortical spreading depression in migraine prophylaxis

scientific article

Sustained functional improvement by hepatocyte growth factor-like small molecule BB3 after focal cerebral ischemia in rats and mice

scientific article

The impact of anesthetics and hyperoxia on cortical spreading depression

scientific article published on 11 April 2008

The sirtuin-2 inhibitor AK7 is neuroprotective in models of Parkinson's disease but not amyotrophic lateral sclerosis and cerebral ischemia

scientific article

Timing of neurologic deterioration in massive middle cerebral artery infarction: a multicenter review

scientific article

Translational MR Neuroimaging of Stroke and Recovery

scientific article

Two-photon microscopy of cortical NADH fluorescence intensity changes: correcting contamination from the hemodynamic response

scientific article

Vagus nerve stimulation inhibits cortical spreading depression

scientific article

List of works by Cenk Ayata

Aag-initiated base excision repair promotes ischemia reperfusion injury in liver, brain, and kidney

Abnormal synaptic Ca(2+) homeostasis and morphology in cortical neurons of familial hemiplegic migraine type 1 mutant mice

Achieving normothermia in patients with febrile subarachnoid hemorrhage: feasibility and safety of a novel intravascular cooling catheter

Age-dependent cerebrovascular dysfunction in a transgenic mouse model of cerebral amyloid angiopathy

Age-related decline in oligodendrogenesis retards white matter repair in mice

Androgenic suppression of spreading depression in familial hemiplegic migraine type 1 mutant mice

Anesthesia in Experimental Stroke Research

CADASIL: experimental insights from animal models ⬇️

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy syndrome mutations increase susceptibility to spreading depression

Cerebrovascular lesions induce transient β-amyloid deposition

Comparative Effectiveness of Calabadion and Sugammadex to Reverse Non-depolarizing Neuromuscular-blocking Agents

Concussive injury before or after controlled cortical impact exacerbates histopathology and functional outcome in a mixed traumatic brain injury model in mice

Cortical spreading depression and migraine

Cortical spreading depression as a target for anti-migraine agents

Cortical spreading depression impairs oxygen delivery and metabolism in mice

Cortical spreading depression triggers migraine attack: pro.

Decreased microvascular cerebral blood flow assessed by diffuse correlation spectroscopy after repetitive concussions in mice

Emerging concepts in sporadic cerebral amyloid angiopathy

Endothelial dysfunction abrogates the efficacy of normobaric hyperoxia in stroke

Endovascular thrombectomy and post-procedural headache

Enhanced subcortical spreading depression in familial hemiplegic migraine type 1 mutant mice

Etomidate and Ketamine: Residual Motor and Adrenal Dysfunction that Persist beyond Recovery from Loss of Righting Reflex in Rats

Fingolimod exerts neuroprotective effects in a mouse model of intracerebral hemorrhage

Gabapentin reduces infarct volume but does not suppress peri-infarct depolarizations

Gabapentin suppresses cortical spreading depression susceptibility

Genetic Animal Models of Cerebral Vasculopathies ⬇️

Genetic and hormonal factors modulate spreading depression and transient hemiparesis in mouse models of familial hemiplegic migraine type 1.

Glucose Modulation of Spreading Depression Susceptibility ⬇️

High-flow oxygen therapy for treatment of acute migraine: A randomized crossover trial

High-resolution in vivo optical imaging of stroke injury and repair

Hyperlipidemia Disrupts Cerebrovascular Reflexes and Worsens Ischemic Perfusion Defect ⬇️

Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease

Imaging PEG-like nanoprobes in tumor, transient ischemia, and inflammatory disease models

Increased glucose availability does not restore prolonged spreading depression durations in hypotensive rats without brain injury ⬇️

Intensive care management of specific stroke treatment

Ischaemic brain oedema

Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue

Laser speckle flowmetry for the study of cerebrovascular physiology in normal and ischemic mouse cortex

Lasting pure-motor deficits after focal posterior internal capsule white-matter infarcts in rats

Late-onset thermal hypersensitivity after focal ischemic thalamic infarcts as a model for central post-stroke pain in rats

Linking Notch signaling to ischemic stroke

Micro-heterogeneity of flow in a mouse model of chronic cerebral hypoperfusion revealed by longitudinal Doppler optical coherence tomography and angiography

Microemboli may link spreading depression, migraine aura, and patent foramen ovale

Migraine and stroke: in search of shared mechanisms

Migraine mutations impair hippocampal learning despite enhanced long-term potentiation

Migraine mutations increase stroke vulnerability by facilitating ischemic depolarizations

Migraine pathophysiology: lessons from mouse models and human genetics

Migraine prophylaxis, ischemic depolarizations, and stroke outcomes in mice

Mild induced hypertension improves blood flow and oxygen metabolism in transient focal cerebral ischemia

Multiparametric, longitudinal optical coherence tomography imaging reveals acute injury and chronic recovery in experimental ischemic stroke

Normobaric hyperoxia improves cerebral blood flow and oxygenation, and inhibits peri-infarct depolarizations in experimental focal ischaemia

Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis

Oligodendrocyte precursors induce early blood-brain barrier opening after white matter injury ⬇️

Optical coherence tomography for the quantitative study of cerebrovascular physiology ⬇️

Pearls and pitfalls in experimental models of spreading depression ⬇️

Perfusion pressure-dependent recovery of cortical spreading depression is independent of tissue oxygenation over a wide physiologic range

Pharmacological targeting of spreading depression in migraine ⬇️

Phase III Preclinical Trials in Translational Stroke Research: Community Response on Framework and Guidelines

Preclinical phase III trials in translational stroke research: call for collective design of framework and guidelines

Pronounced hypoperfusion during spreading depression in mouse cortex

Quantitative Imaging of Cerebral Blood Flow Velocity and Intracellular Motility using Dynamic Light Scattering–Optical Coherence Tomography ⬇️

Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms

Rho-kinase inhibition improves ischemic perfusion deficit in hyperlipidemic mice

Selective ROCK2 inhibition in focal cerebral ischemia

Sensitivity to acute cerebral ischemic injury in migraineurs: A retrospective case-control study

Simultaneous imaging of cerebral partial pressure of oxygen and blood flow during functional activation and cortical spreading depression

Simultaneous multispectral reflectance imaging and laser speckle flowmetry of cerebral blood flow and oxygen metabolism in focal cerebral ischemia

Spreading Depolarizations: A Therapeutic Target Against Delayed Cerebral Ischemia After Subarachnoid Hemorrhage

Spreading Depression and Neurovascular Coupling ⬇️

Spreading Depression in Primary and Secondary Headache Disorders

Spreading Depression, Spreading Depolarizations, and the Cerebral Vasculature

Spreading depression and the clinical correlates of migraine

Subarachnoid hemorrhage, spreading depolarizations and impaired neurovascular coupling

Supply-demand mismatch transients in susceptible peri-infarct hot zones explain the origins of spreading injury depolarizations

Suppression of cortical spreading depression in migraine prophylaxis

Sustained functional improvement by hepatocyte growth factor-like small molecule BB3 after focal cerebral ischemia in rats and mice

The impact of anesthetics and hyperoxia on cortical spreading depression

The sirtuin-2 inhibitor AK7 is neuroprotective in models of Parkinson's disease but not amyotrophic lateral sclerosis and cerebral ischemia

Timing of neurologic deterioration in massive middle cerebral artery infarction: a multicenter review