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List of works by Marja-Leena Linne

A model integrating the cerebellar granule neuron excitability and calcium signaling pathways

A novel approach to model neuronal signal transduction using stochastic differential equations

Astrocyte-mediated spike-timing-dependent long-term depression modulates synaptic properties in the developing cortex

scientific article published on 10 November 2020

Astrocyte-neuron interactions: from experimental research-based models to translational medicine

scientific article published on January 2014

Biophysical Psychiatry-How Computational Neuroscience Can Help to Understand the Complex Mechanisms of Mental Disorders

scientific article published on 06 August 2019

Challenges in Reproducibility, Replicability, and Comparability of Computational Models and Tools for Neuronal and Glial Networks, Cells, and Subcellular Structures.

scientific article published in May 2018

Combining hypothesis- and data-driven neuroscience modeling in FAIR workflows

scientific article published on 06 July 2022

Comparison of models for IP3 receptor kinetics using stochastic simulations

scientific article

Computational Models for Calcium-Mediated Astrocyte Functions

scientific article published on 4 April 2018

Computational methods for estimation of cell cycle phase distributions of yeast cells

scientific article published on January 2007

Computational study of noise in a large signal transduction network

scientific article

Computational study of structural changes in neuronal networks during growth: a model of dissociated neocortical cultures.

scientific article published on 18 July 2011

Contribution of SERCA and IP3 sensitivity to calcium signaling in astrocytes: a computational study

scientific article

Crete, channels, cells, circuits and computers1The Crete Course in Computational Neuroscience is supported by the European Commission (ERBFMMACT950036), by The Brain Science Foundation (Tokyo), by UNESCO (96GRE302) and by Sun Microsystems. The next c

scientific article published on 01 February 1997

Developing Itô stochastic differential equation models for neuronal signal transduction pathways

scientific article published in August 2006

Discrete stochastic simulation of cell signaling: comparison of computational tools

scientific article published in January 2006

Effects of transmitters and amyloid-beta peptide on calcium signals in rat cortical astrocytes: Fura-2AM measurements and stochastic model simulations

scientific article

Estimation of Neuronal Signaling Model Parameters using Deterministic and Stochastic in Silico Training Data: Evaluation of Four Parameter Estimation Methods

Impacts of laminin and polyethyleneimine surface coatings on morphology of differentiating human SH-SY5Y cells and networks

Information diversity in structure and dynamics of simulated neuronal networks

scientific article published on June 2011

Modeling Neuron-Astrocyte Interactions: Towards Understanding Synaptic Plasticity and Learning in the Brain

article by Riikka Havela et al published 2017 in Lecture Notes in Computer Science

Modeling signal transduction in synaptic plasticity: comparison of models and methods.

scientific article published on 20 July 2010

Modeling signal transduction leading to synaptic plasticity: evaluation and comparison of five models

scientific article published on 29 March 2011

Morphological Differentiation Towards Neuronal Phenotype of SH-SY5Y Neuroblastoma Cells by Estradiol, Retinoic Acid and Cholesterol

scientific article published on 30 October 2015

Neuroinformatics and Computational Modelling as Complementary Tools for Neurotoxicology Studies

scholarly article by Marja-Leena Linne published September 2018 in Basic and Clinical Pharmacology and Toxicology

Numerical characterization of noisy fluctuations in two different types of stochastic differential equation models of neural signaling

scientific article published on 4 December 2015

Order reduction for a signaling pathway model of neuronal synaptic plasticity

article by Mikko Lehtimäki et al published July 2017 in IFAC Proceedings Volumes

Parameter Estimation and Tuning of Firefly Luciferase Pathway Model

Postsynaptic signal transduction models for long-term potentiation and depression

scientific article

Quantification of vesicles in differentiating human SH-SY5Y neuroblastoma cells by automated image analysis

scientific article published on 13 December 2005

Reproducibility and Comparability of Computational Models for Astrocyte Calcium Excitability

scientific article

Simulation tools for biochemical networks: evaluation of performance and usability

scientific article

Stochastic differential equation model for cerebellar granule cell excitability

scientific article

Structure-dynamics relationships in bursting neuronal networks revealed using a prediction framework

scientific article (publication date: 2013)

The effects of neuron morphology on graph theoretic measures of network connectivity: the analysis of a two-level statistical model

scientific article published on 10 June 2015

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