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List of works by Francesca Demichelis

A Comparative Study of ERG Status Assessment on DNA, mRNA, and Protein Levels Using Unique Samples from a Swedish Biopsy Cohort

article

A Phase II Trial of the Aurora Kinase A Inhibitor Alisertib for Patients with Castration-resistant and Neuroendocrine Prostate Cancer: Efficacy and Biomarkers

scientific article published on 19 September 2018

A computational framework discovers new copy number variants with functional importance

scientific article

A hierarchical Naïve Bayes Model for handling sample heterogeneity in classification problems: an application to tissue microarrays.

scientific article

A step toward functionally characterized prostate cancer molecular subtypes ⬇️

scientific article published on August 1, 2013

ABEMUS: platform specific and data informed detection of somatic SNVs in cfDNA

scientific article published on 10 January 2020

ASEQ: fast allele-specific studies from next-generation sequencing data.

scientific article

Accuracy of telepathology

scientific article published on 01 January 2004

An automated procedure to properly handle digital images in large scale tissue microarray experiments.

scientific article published on September 2005

Antibody-based detection of ERG rearrangement-positive prostate cancer

scientific article

Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma

scientific article (publication date: 11 December 2007)

Association of cytokeratin 7 and 19 expression with genomic stability and favorable prognosis in clear cell renal cell cancer

article published in 2008

Automated immunofluorescence analysis defines microvessel area as a prognostic parameter in clear cell renal cell cancer

article

Biology and evolution of poorly differentiated neuroendocrine tumors

scientific article published in June 2017

Clonal evolution of chemotherapy-resistant urothelial carcinoma.

scientific article published on 17 October 2016

DIAPH3 governs the cellular transition to the amoeboid tumour phenotype ⬇️

scientific article published on May 16, 2012

Defining aggressive prostate cancer using a 12-gene model

scientific article

Defining order and timing of mutations during cancer progression: the TO-DAG probabilistic graphical model

scientific article

Design and initial implementation of a regional tele-oncology project

scientific article published on 01 January 2000

Digital Pathology: Science Fiction?

scientific article published on October 2000

Digital storage of glass slides for quality assurance in histopathology and cytopathology

scientific article

Discovery of non-ETS gene fusions in human prostate cancer using next-generation RNA sequencing

scientific article

Distinct ERG rearrangement prevalence in prostate cancer: higher frequency in young age and in low PSA prostate cancer.

scientific article published on 5 February 2013

Distinct genomic aberrations associated with ERG rearranged prostate cancer

scientific article published on April 2009

Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer

scientific article published on 8 February 2016

EML4-ALK fusion lung cancer: a rare acquired event

scientific article

ERG cooperates with androgen receptor in regulating trefoil factor 3 in prostate cancer disease progression

scientific article

ERG rearrangement metastasis patterns in locally advanced prostate cancer

scientific article published on April 2010

Epigenetic repression of miR-31 disrupts androgen receptor homeostasis and contributes to prostate cancer progression

scientific article published on 11 December 2012

Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer

scientific article

Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer

scientific article

FusionSeq: a modular framework for finding gene fusions by analyzing Paired-End RNA-Sequencing data

scientific article (publication date: 2010)

Genetic predisposition to prostate cancer: Update and future perspectives

scientific article published on 02 July 2014

Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer

scientific article

Genome-Wide Linkage Analysis of TMPRSS2-ERG Fusion in Familial Prostate Cancer

article

Genome-wide DNA methylation events in TMPRSS2-ERG fusion-negative prostate cancers implicate an EZH2-dependent mechanism with miR-26a hypermethylation

scientific article published on 28 August 2012

Genomic Correlates to the Newly Proposed Grading Prognostic Groups for Prostate Cancer

scientific article published on 9 November 2015

Identification of functionally active, low frequency copy number variants at 15q21.3 and 12q21.31 associated with prostate cancer risk

scientific article published on 10 April 2012

Impact of constitutional copy number variants on biological pathway evolution

scientific article

In-silico identification and functional validation of allele-dependent AR enhancers

scientific article published on March 2015

Inherited variant in NFκB-1 promoter is associated with increased risk of IBD in an Algerian population and modulates SOX9 binding

scientific article published on 20 February 2020

Integrative Clinical Genomics of Advanced Prostate Cancer

scientific article

Integrative clinical genomics of advanced prostate cancer

scientific article

Integrative microarray analysis of pathways dysregulated in metastatic prostate cancer

scientific article published in November 2007

Internet-based Profiler system as integrative framework to support translational research

scientific article

Intrapatient heterogeneity in prostate cancer

scientific article published on 28 July 2015

JAGGED1 expression is associated with prostate cancer metastasis and recurrence

scientific article

Large oncosomes in human prostate cancer tissues and in the circulation of mice with metastatic disease

scientific article

Large oncosomes mediate intercellular transfer of functional microRNA.

scientific article

M-CAM expression as marker of poor prognosis in epithelial ovarian cancer

scientific article published on October 2006

Molecular archeology: unearthing androgen-induced structural rearrangements in prostate cancer genomes

scientific article

Molecular characterization of TMPRSS2-ERG gene fusion in the NCI-H660 prostate cancer cell line: a new perspective for an old model.

scientific article

Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets

scientific article

Molecular genetics of prostate cancer: emerging appreciation of genetic complexity ⬇️

scientific article published on January 1, 2012

Molecular sampling of prostate cancer: a dilemma for predicting disease progression

scientific article

Morphological features of TMPRSS2-ERG gene fusion prostate cancer

scientific article published in May 2007

Mutation-selection balance and compensatory mechanisms in tumour evolution

scientific article published on 30 November 2020

N-Myc Induces an EZH2-Mediated Transcriptional Program Driving Neuroendocrine Prostate Cancer

scientific journal article

N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer

scientific article

Next generation sequencing of prostate cancer from a patient identifies a deficiency of methylthioadenosine phosphorylase, an exploitable tumor target

scientific article

Nine-gene molecular signature is not associated with prostate cancer death in a watchful waiting cohort

scientific article published in January 2008

Oncogene-mediated alterations in chromatin conformation

scientific article

Oncosome formation in prostate cancer: association with a region of frequent chromosomal deletion in metastatic disease

scientific article

PCAT-1, a long noncoding RNA, regulates BRCA2 and controls homologous recombination in cancer

scientific article

Patient derived organoids to model rare prostate cancer phenotypes.

scientific article

Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine

scientific article

Plasma AR and abiraterone-resistant prostate cancer.

scientific article

Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover

scientific article published on 4 April 2013

Publisher Correction: Mutation-selection balance and compensatory mechanisms in tumour evolution

scientific article published on 14 December 2020

Publisher Correction: The long tail of oncogenic drivers in prostate cancer

scientific article published on 01 July 2019

Punctuated evolution of prostate cancer genomes

scientific article published on April 2013

RB1 Heterogeneity in Advanced Metastatic Castration Resistant Prostate Cancer

scientific article published on 26 September 2018

Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma

scientific article

Recurrent prostate cancer genomic alterations predict response to brachytherapy treatment

scientific article

Response to ‘TMPRSS2-ERG gene fusions are infrequent in prostatic ductal adenocarcinomas’

article

Robotic telepathology for intraoperative remote diagnosis using a still-imaging-based system

scientific article

Role of specialized composition of SWI/SNF complexes in prostate cancer lineage plasticity

scientific article published on 03 November 2020

SLC45A3-ELK4 is a novel and frequent erythroblast transformation-specific fusion transcript in prostate cancer

scientific article

SNP panel identification assay (SPIA): a genetic-based assay for the identification of cell lines

scientific article published on 27 February 2008

SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer

scientific article

SPOP mutation leads to genomic instability in prostate cancer.

scientific article

SPOP mutations in prostate cancer across demographically diverse patient cohorts.

scientific article published on January 2014

Second generation imaging of nuclear/cytoplasmic HIV-1 complexes

scientific article published on 6 June 2014

Skp2 expression is associated with high risk and elevated Ki67 expression in gastrointestinal stromal tumours

scientific article

TMABoost: an integrated system for comprehensive management of tissue microarray data.

scientific article

TMPRSS2-ERG Fusion Prostate Cancer: An Early Molecular Event Associated With Invasion

scientific article published on 01 June 2007

TMPRSS2-ERG fusion heterogeneity in multifocal prostate cancer: clinical and biologic implications

scientific article published on October 2007

TMPRSS2-ETS fusion prostate cancer: biological and clinical implications

scientific article published on November 2007

TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer

scientific article published on September 2006

TMPRSS2:ERG gene fusion associated with lethal prostate cancer in a watchful waiting cohort.

scientific article published on 22 January 2007

Telemetric intraoperative diagnosis among hospitals in Trentino: first evaluations and optimization of the procedure

scientific article

Testing a multigene signature of prostate cancer death in the Swedish Watchful Waiting Cohort

scientific article published on 26 June 2008

Testing mutual exclusivity of ETS rearranged prostate cancer

scientific article

The Lethal Clone in Prostate Cancer: Redefining the Index

scientific article published on 02 January 2014

The MicroArray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

scientific article

The genomic complexity of primary human prostate cancer

scientific article

The landscape of somatic copy-number alteration across human cancers

scientific article

The long tail of oncogenic drivers in prostate cancer.

scientific article published on 2 April 2018

The role of SPINK1 in ETS rearrangement-negative prostate cancers

scientific article

The virtual case: a new method to completely digitize cytological and histological slides.

scientific article

Tumor clone dynamics in lethal prostate cancer

scientific article published on September 2014

Two distinct immunopathological profiles in autopsy lungs of COVID-19

scientific article published on 08 October 2020

Unraveling the clonal hierarchy of somatic genomic aberrations.

scientific article

User attitudes in analyzing digital slides in a quality control test bed: a preliminary study

scientific article published in May 2006

V-ets erythroblastosis virus E26 oncogene homolog (avian)/Trefoil factor 3/high-molecular-weight cytokeratin triple immunostain: a novel tissue-based biomarker in prostate cancer with potential clinical application

scientific article published on 12 July 2013

Variants at IRX4 as prostate cancer expression quantitative trait loci

scientific article published on 11 September 2013

Whole-Exome Sequencing of Metastatic Cancer and Biomarkers of Treatment Response.

scientific article published in July 2015

[The needs of elderly or disabled inmates in Basse-Normandie]

scientific article published on 01 March 2011

[Tissue microarrays in oncology]

scientific article published on 01 October 2003

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