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List of works by Janna Morrison

A review of fundamental principles for animal models of DOHaD research: an Australian perspective.

scientific article

Activation of IGF-2R stimulates cardiomyocyte hypertrophy in the late gestation sheep fetus.

scientific article published on 28 August 2012

Adverse Intrauterine Environment and Cardiac miRNA Expression.

scientific article published on 6 December 2017

Akt signaling as a mediator of cardiac adaptation to low birth weight.

scientific article published on 20 February 2017

Alteration of cardiac glucose metabolism in association to low birth weight: experimental evidence in lambs with left ventricular hypertrophy.

scientific article published on 5 August 2013

And the beat goes on

scientific article published on 08 October 2018

Antenatal glucocorticoid treatment of the growth-restricted fetus: benefit or cost?

scientific article published on 10 March 2009

Antenatal steroids and the IUGR fetus: are exposure and physiological effects on the lung and cardiovascular system the same as in normally grown fetuses?

scientific article

Antidepressant Use in Late Gestation and Breastfeeding Rates at Discharge from Hospital.

scientific article published in December 2016

Antidepressant use and gestational hypertension: does evidence support causality? ⬇️

scientific article published on May 1, 2013

Arginine vasopressin improves cerebral perfusion following controlled haemorrhage in adult ewes

scientific article published on 19 July 2019

Association of early and late maternal smoking during pregnancy with offspring body mass index at 4 to 5 years of age.

scientific article published on 5 October 2015

Basic experimental and clinical advances in the mechanisms underlying abnormal pregnancy outcomes.

scientific article published on 11 February 2013

Cerebral blood flow during spontaneous and cholinergically induced behavioral states in the sheep fetus

scientific article

Changes in cardiac troponins with gestational age explain changes in cardiac muscle contractility in the sheep fetus

scientific article published on 14 April 2011

Chronic hypoxaemia as a molecular regulator of fetal lung development: implications for risk of respiratory complications at birth.

scientific article

Chronic hypoxemia in late gestation decreases cardiomyocyte number but does not change expression of hypoxia-responsive genes

scientific article

Chronic maternal fluoxetine infusion in pregnant sheep: effects on the maternal and fetal hypothalamic-pituitary-adrenal axes

scientific article

Considerations in selecting postoperative analgesia for pregnant sheep following fetal instrumentation surgery

scientific article published on 25 June 2019

Contractile and Ca2+-handling properties of the right ventricular papillary muscle in the late-gestation sheep fetus

scientific article

DOHaD in Indigenous populations: DOHaD, epigenetics, equity and race

scientific article published on 01 February 2019

DOHaD in the land down under: 11th World Congress 2019

scientific article published on 29 September 2020

Detecting metabolic differences in fetal and adult sheep adipose and skeletal muscle tissues

scientific article published on 23 December 2019

Development of an experimental model of maternal allergic asthma during pregnancy

scientific article published on 31 July 2015

Dietary restriction in the periconceptional period in normal-weight or obese ewes results in increased abundance of angiotensin-converting enzyme (ACE) and angiotensin type 1 receptor (AT1R) in the absence of changes in ACE or AT1R methylation in th

scientific article published in October 2013

Differential Response to Injury in Fetal and Adolescent Sheep Hearts in the Immediate Post-myocardial Infarction Period

scientific article published on 05 March 2019

Differential effects of exposure to maternal obesity or maternal weight loss during the periconceptional period in the sheep on insulin signalling molecules in skeletal muscle of the offspring at 4 months of age.

scientific article

Differential effects of late gestation maternal overnutrition on the regulation of surfactant maturation in fetal and postnatal life

scientific article published on 31 July 2017

Differential effects of maternal obesity and weight loss in the periconceptional period on the epigenetic regulation of hepatic insulin-signaling pathways in the offspring

scientific article

Differential gene responses 3 days following infarction in the fetal and adolescent sheep heart ⬇️

scientific article published on 21 January 2020

Does poor fetal growth influence the extent of fetal exposure to maternal medications?

scientific article published on 6 February 2018

Does the intrauterine growth-restricted fetus benefit from antenatal glucocorticoids?

Drugs, chemicals and nutrition during pregnancy: impact on fetal, neonatal and adult health

article

Early origins of heart disease: low birth weight and determinants of cardiomyocyte endowment

scientific article

Early origins of heart disease: low birth weight and the role of the insulin-like growth factor system in cardiac hypertrophy.

scientific article

Early restriction of placental growth results in placental structural and gene expression changes in late gestation independent of fetal hypoxemia

scientific article published on December 2016

Effect of periconceptional nutrition on the growth, behaviour and survival of the neonatal lamb

scientific article published on 24 June 2015

Effects of Maternal Hypoxia during Pregnancy on Bone Development in Offspring: A Guinea Pig Model

scientific article

Embryo number and periconceptional undernutrition in the sheep have differential effects on adrenal epigenotype, growth, and development

scientific article

Epigenetics and human obesity.

scientific article published on 25 February 2014

Evolution, Development, and Function of the Pulmonary Surfactant System in Normal and Perturbed Environments.

scientific article

Exposed or not exposed? Exploring exposure classification in studies using administrative data to investigate outcomes following medication use during pregnancy

scientific article

Exposure to rosiglitazone, a PPAR-γ agonist, in late gestation reduces the abundance of factors regulating cardiac metabolism and cardiomyocyte size in the sheep fetus

scientific article published on 29 January 2014

Feasibility of detecting myocardial infarction in the sheep fetus using late gadolinium enhancement CMR imaging.

scientific article published on 13 September 2017

Feasibility of phase-contrast cine magnetic resonance imaging for measuring blood flow in the sheep fetus.

scientific article published on 13 December 2017

Feasibility of ventricular volumetry by cardiovascular MRI to assess cardiac function in the fetal sheep

scientific article published on 07 May 2020

Fetal cardiovascular response to acute hypoxia during maternal anesthesia

scientific article published on 01 February 2020

Fetal growth restriction and the programming of heart growth and cardiac insulin-like growth factor 2 expression in the lamb.

scientific article

Fetal hemodynamics and cardiac streaming assessed by 4D flow cardiovascular magnetic resonance in fetal sheep

scientific article published on 21 January 2019

GABAA receptor antagonism at the hypoglossal motor nucleus increases genioglossus muscle activity in NREM but not REM sleep

scientific article published on 28 February 2003

Gene expression allelic imbalance in ovine brown adipose tissue impacts energy homeostasis

scientific article

Glycine at hypoglossal motor nucleus: genioglossus activity, CO(2) responses, and the additive effects of GABA.

scientific article published in November 2002

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

IGF-2R-Gαq signaling and cardiac hypertrophy in the low-birth-weight lamb

scientific article

IGF-2R-mediated signaling results in hypertrophy of cultured cardiomyocytes from fetal sheep.

scientific article published on 22 June 2012

IUGR decreases cardiomyocyte endowment and alters cardiac metabolism in a sex and cause of IUGR specific manner.

scientific article published on 21 March 2018

Imaging and lipidomics methods for lipid analysis in metabolic and cardiovascular disease

scientific article

Impact of chronic hypoxemia on blood flow to the brain, heart, and adrenal gland in the late-gestation IUGR sheep fetus

scientific article published on 26 November 2014

Impact of embryo number and maternal undernutrition around the time of conception on insulin signaling and gluconeogenic factors and microRNAs in the liver of fetal sheep

scientific article

Impact of embryo number and periconceptional undernutrition on factors regulating adipogenesis, lipogenesis, and metabolism in adipose tissue in the sheep fetus

scientific article

Impact of in vitro embryo culture and transfer on blood pressure regulation in the adolescent lamb

scientific article published on 13 November 2020

Impact of maternal overnutrition on gluconeogenic factors and methylation of the phosphoenolpyruvate carboxykinase promoter in the fetal and postnatal liver

scientific article published on 14 October 2013

Impact of maternal undernutrition around the time of conception on factors regulating hepatic lipid metabolism and microRNAs in singleton and twin fetuses

scientific article

Impact of periconceptional and preimplantation undernutrition on factors regulating myogenesis and protein synthesis in muscle of singleton and twin fetal sheep

scientific article published on August 2015

Improving pregnancy outcomes in humans through studies in sheep

article published in 2018

Increased lung prolyl hydroxylase and decreased glucocorticoid receptor are related to decreased surfactant protein in the growth-restricted sheep fetus

scientific article

Intrafetal glucose infusion alters glucocorticoid signaling and reduces surfactant protein mRNA expression in the lung of the late-gestation sheep fetus.

scientific article published on 2 July 2014

Intrauterine growth restriction and differential patterns of hepatic growth and expression of IGF1, PCK2, and HSDL1 mRNA in the sheep fetus in late gestation.

scientific article

Intrauterine growth restriction may reduce hepatic drug metabolism in the early neonatal period

scientific article published on 08 June 2018

Introduction: Celebrating Emeritus Scientia Professor Eugenie R Lumbers AM and Professor Caroline McMillen.

scientific article published in November 2013

Investigating Intracellular Localisation and Cytotoxicity Trends for Neutral and Cationic Iridium Tetrazolato Complexes in Live Cells.

scientific article

Investigating outcomes associated with medication use during pregnancy: a review of methodological challenges and observational study designs.

scientific article published on 04 February 2012

Investigating outcomes following the use of selective serotonin reuptake inhibitors for treating depression in pregnancy: a focus on methodological issues

scientific article

Invited review: guinea pig models for translation of DOHaD into the clinic.

scientific article published on 6 April 2018

Is There a Dirty Side to Personal Care Products?

scientific article published on 01 July 2016

Label-free imaging of healthy and infarcted fetal sheep hearts by two-photon microscopy.

scientific article

Label-free imaging of redox status and collagen deposition showing metabolic differences in the heart

scientific article published on 23 October 2017

Limited fetal metabolism of rosiglitazone: Elimination via the maternal compartment in the pregnant ewe

scientific article published on 08 April 2016

Long term impact of prenatal exposure to SSRIs on growth and body weight in childhood: evidence from animal and human studies.

scientific article published on 13 March 2012

Long-term effects of prenatal SSRI exposure on child growth: weighing the evidence.

scientific article published in November 2013

Low birth weight activates the renin-angiotensin system, but limits cardiac angiogenesis in early postnatal life

scientific article

Maternal Nutrient Restriction Alters Ca2+ Handling Properties and Contractile Function of Isolated Left Ventricle Bundles in Male But Not Female Juvenile Rats

scientific article

Maternal allergic asthma during pregnancy alters fetal lung and immune development in sheep: potential mechanisms for programming asthma and allergy

scientific article published on 03 July 2019

Maternal chronic hypoxia increases expression of genes regulating lung liquid movement and surfactant maturation in male fetuses in late gestation.

scientific article published on 20 March 2017

Maternal dietary restriction during the periconceptional period in normal-weight or obese ewes results in adrenocortical hypertrophy, an up-regulation of the JAK/STAT and down-regulation of the IGF1R signaling pathways in the adrenal of the postnata

scientific article published on 09 October 2013

Maternal fluoxetine infusion does not alter fetal endocrine and biophysical circadian rhythms in pregnant sheep

scientific article published in July 2005

Maternal obesity and the early origins of childhood obesity: weighing up the benefits and costs of maternal weight loss in the periconceptional period for the offspring

scientific article published on 7 December 2011

Maternal obesity mediated predisposition to respiratory complications at birth and in later life: understanding the implications of the obesogenic intrauterine environment.

scientific article published on 11 October 2016

Maternal obesity or weight loss around conception impacts hepatic fatty acid metabolism in the offspring

scientific article published on 10 April 2014

Maternal periconceptional and first trimester protein restriction in beef heifers: effects on placental parameters and fetal and neonatal calf development

scientific article published on 01 March 2020

Maternal sleep during pregnancy and poor fetal outcomes: A scoping review of the literature with meta-analysis

article

Maternal undernutrition around the time of conception and embryo number each impact on the abundance of key regulators of cardiac growth and metabolism in the fetal sheep heart

scientific article published in October 2013

Maternal undernutrition during the first week after conception results in decreased expression of glucocorticoid receptor mRNA in the absence of GR exon 17 hypermethylation in the fetal pituitary in late gestation

scientific article published in October 2013

Maternal undernutrition in late gestation increases IGF2 signalling molecules and collagen deposition in the right ventricle of the fetal sheep heart

scientific article published on 20 May 2018

Maternal undernutrition reduces P-glycoprotein in guinea pig placenta and developing brain in late gestation

scientific article

Mature Surfactant Protein-B Expression by Immunohistochemistry as a Marker for Surfactant System Development in the Fetal Sheep Lung

scientific article published on 21 August 2015

Methamphetamine administration increases hepatic CYP1A2 but not CYP3A activity in female guinea pigs

scientific article published on 12 May 2020

Methodological challenges in using routinely collected health data to investigate long-term effects of medication use during pregnancy

scientific article

Mitochondrial imaging in live or fixed tissues using a luminescent iridium complex.

scientific article

Modifying Maternal Sleep Position in Late Pregnancy Through Positional Therapy: A Feasibility Study

Molecular regulation of lung maturation in near-term fetal sheep by maternal daily vitamin C treatment in late gestation

scientific article published on 15 April 2021

Neonatal outcomes after late-gestation exposure to selective serotonin reuptake inhibitors

scientific article published in October 2012

No evidence for an enhanced role of endothelial nitric oxide in the maintenance of arterial blood pressure in the IUGR sheep fetus.

scientific article

Normal human and sheep fetal vessel oxygen saturations by T2 magnetic resonance imaging

scientific article published on 05 May 2020

Normalisation of surfactant protein -A and -B expression in the lungs of low birth weight lambs by 21 days old.

scientific article published on 26 September 2017

Nutrition in Pregnancy: Optimising Maternal Diet and Fetal Adaptations to Altered Nutrient Supply

scientific article published on 4 June 2016

PPARγ activation in late gestation does not promote surfactant maturation in the fetal sheep lung

scientific article published on 07 January 2021

Periconceptional nutrition and the early programming of a life of obesity or adversity.

scientific article published on 17 December 2010

Periconceptional undernutrition programs changes in insulin-signaling molecules and microRNAs in skeletal muscle in singleton and twin fetal sheep

scientific article published on 9 January 2014

Placental adaptations in growth restriction

scientific article

Placental glucocorticoid receptor isoforms in a sheep model of maternal allergic asthma

scientific article published on 28 June 2019

Postnatal consequences of prenatal nicotine exposure. Preface

scientific article published on 01 June 2015

Prenatal antidepressant exposure and child behavioural outcomes at 7 years of age: a study within the Danish National Birth Cohort.

scientific article published on 15 September 2015

Prenatal development of the pulmonary surfactant system and the influence of hypoxia.

scientific article published on 27 May 2011

Prenatal exposure to selective serotonin reuptake inhibitors and childhood overweight at 7 years of age.

scientific article published on 7 October 2013

Prenatal exposure to selective serotonin reuptake inhibitors and risk of childhood overweight

scientific article published in August 2012

Recent developments on the role of epigenetics in obesity and metabolic disease

scientific article published on 11 July 2015

Regulation of fetal lung development in response to maternal overnutrition.

scientific article

Regulation of lung maturation by prolyl hydroxylase domain inhibition in the lung of the normally grown and placentally restricted fetus in late gestation.

scientific article published on 2 March 2016

Regulation of microRNA during cardiomyocyte maturation in sheep.

scientific article published on 22 July 2015

Restriction of placental function alters heart development in the sheep fetus

scientific article published on 11 April 2007

Restriction of placental growth results in greater hypotensive response to alpha-adrenergic blockade in fetal sheep during late gestation

scientific article published on 13 January 2005

Risk of Respiratory Distress Syndrome and Efficacy of Glucocorticoids: Are They the Same in the Normally Grown and Growth-Restricted Infant?

scientific article

Role of endogenous serotonin in modulating genioglossus muscle activity in awake and sleeping rats

scientific article published on 14 July 2005

Role of inhibitory amino acids in control of hypoglossal motor outflow to genioglossus muscle in naturally sleeping rats

scientific article published on 22 August 2003

Rosiglitazone increases the expression of peroxisome proliferator-activated receptor-gamma target genes in adipose tissue, liver, and skeletal muscle in the sheep fetus in late gestation.

scientific article

Scientific Abstracts

Second-harmonic generation and two-photon-excited autofluorescence microscopy of cardiomyocytes: quantification of cell volume and myosin filaments

scientific article published in November 2008

Seeing the fetus from a DOHaD perspective: discussion paper from the advanced imaging techniques of DOHaD applications workshop held at the 2019 DOHaD World Congress

scientific article published on 21 September 2020

Sheep models of intrauterine growth restriction: fetal adaptations and consequences.

scientific article published on July 2008

Simple HPLC method for determination of rosiglitazone in sheep plasma and amniotic fluid and its application in a pregnant sheep model

scientific article published on 31 January 2011

Structural and molecular regulation of lung maturation by intratracheal vascular endothelial growth factor administration in the normally grown and placentally restricted fetus.

scientific article published on 5 November 2015

Subcutaneous maternal resveratrol treatment increases uterine artery blood flow in the pregnant ewe and increases fetal but not cardiac growth

scientific article published on 01 October 2019

Systematic review: Impact of resveratrol exposure during pregnancy on maternal and fetal outcomes in animal models of human pregnancy complications-Are we ready for the clinic?

scientific article published on 25 April 2019

Technique for comprehensive fetal hepatic blood flow assessment in sheep using 4D flow MRI

scientific article published on 13 June 2020

The Australian Early Origins of Hypertension workshop: a celebration of the scientific contributions made by emeritus Scientia professor Eugenie R lumbers AM and professor Caroline McMillen

article

The Development of the Pulmonary Surfactant System

article

The early origins of later obesity: pathways and mechanisms

scientific article published on January 2009

The early origins of obesity and insulin resistance: timing, programming and mechanisms.

scientific article published on 14 September 2015

The effect of placental restriction on insulin signaling and lipogenic pathways in omental adipose tissue in the postnatal lamb.

scientific article

The fetal sheep lung does not respond to cortisol infusion during the late canalicular phase of development

scientific article

The periconceptional environment and cardiovascular disease: does in vitro embryo culture and transfer influence cardiovascular development and health?

scientific article

The reliance on α-adrenergic receptor stimuli for blood pressure regulation in the chronically hypoxaemic fetus is not dependent on post-ganglionic activation

scientific article published on 21 December 2020

The role of miRNA regulation in fetal cardiomyocytes, cardiac maturation and the risk of heart disease in adults

scientific article published on 28 June 2018

Umbilical vein infusion of Prostaglandin I2 increases ductus venosus shunting of oxygen rich blood but does not increase cerebral oxygen delivery in the fetal sheep

scientific article published on 10 August 2020

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