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List of works by Antonello Di Paolo

5-fluorouracil pharmacokinetics predicts disease-free survival in patients administered adjuvant chemotherapy for colorectal cancer.

scientific article published in May 2008

A case report of a TDM-guided optimization of mitotane for a safe and effective long-term treatment

scientific article published on 04 March 2019

A dose finding and pharmacokinetic study of capecitabine in combination with oxaliplatin and irinotecan in metastatic colorectal cancer.

scientific article published on 7 October 2008

A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients.

scientific article published on 25 March 2008

A pharmacokinetic-based test to prevent severe 5-fluorouracil toxicity

scientific article published on 01 October 2006

A phase I and pharmacokinetic study of irinotecan given as a 7-day continuous infusion in metastatic colorectal cancer patients pretreated with 5-fluorouracil or raltitrexed.

scientific article published in March 2004

A phase I study of continuous hepatic arterial infusion of Irinotecan in patients with locally advanced hepatocellular carcinoma

scientific article published on 13 September 2011

A rapid high-performance liquid chromatography method to measure linezolid and daptomycin concentrations in human plasma

scientific article published in April 2010

ABCB1 polymorphisms are associated with clozapine plasma levels in psychotic patients

scientific article published in August 2009

Acetylcholinesterase blockade does not account for the adverse cardiovascular effects of the antitumor drug irinotecan: a preclinical study.

scientific article published in December 2001

An exploratory study on pharmacogenetics of inosine-monophosphate dehydrogenase II in peripheral mononuclear cells from liver-transplant recipients.

scientific article published in November 2004

An improved HPLC method for therapeutic drug monitoring of daunorubicin, idarubicin, doxorubicin, epirubicin, and their 13-dihydro metabolites in human plasma

scientific article published on 01 June 1999

Association of the hOCT1/ABCB1 genotype with efficacy and tolerability of imatinib in patients affected by chronic myeloid leukemia.

scientific article

Biweekly chemotherapy with oxaliplatin, irinotecan, infusional Fluorouracil, and leucovorin: a pilot study in patients with metastatic colorectal cancer

scientific article published in October 2002

Cardiovascular implantable electronic device endocarditis treated with daptomycin with or without transvenous removal.

scientific article published on 20 March 2012

Case report of a successful treatment of methicillin-resistant Staphylococcus aureus (MRSA) bacteremia and MRSA/vancomycin-resistant Enterococcus faecium cholecystitis by daptomycin.

scientific article published on 22 February 2011

Cholinergic toxic syndrome by the anticancer drug irinotecan: acetylcholinesterase does not play a major role.

scientific article

Chronic administration of suramin induces neurotoxicity in rats.

scientific article published in November 1997

Clinical and experimental pharmacokinetic interaction between 6-mercaptopurine and methotrexate

scientific article published on 01 January 1996

Clinical pharmacokinetics of antibacterials in cerebrospinal fluid.

scientific article published on July 2013

Clinical, pharmacokinetic and pharmacodynamic evaluations of metronomic UFT and cyclophosphamide plus celecoxib in patients with advanced refractory gastrointestinal cancers

scientific article published on 2 March 2012

Comparative pharmacokinetic and pharmacodynamic evaluation of branded and generic formulations of meloxicam in healthy male volunteers

scientific article published on 24 July 2013

Daptomycin concentrations in valve tissue and vegetation in patients with bacterial endocarditis

scientific article published on 22 October 2012

Different recommendations for daptomycin dosing over time in patients with severe infections

scientific article published on 11 April 2014

Dihydropyrimidine dehydrogenase polymorphisms and fluoropyrimidine toxicity: ready for routine clinical application within personalized medicine?

scientific article

Drug therapeutic failures in emergency department patients. A university hospital experience.

scientific article published in January 2004

EGFR ligands as pharmacodynamic biomarkers in metastatic colorectal cancer patients treated with cetuximab and irinotecan.

scientific article published on 3 July 2013

Fungicidal activity and PK/PD of caspofungin as tools to guide antifungal therapy in a fluconazole-resistant C. parapsilosis candidemia

scientific article published on 15 February 2017

Generic Substitution of Orphan Drugs for the Treatment of Rare Diseases: Exploring the Potential Challenges

scientific article published on 20 February 2018

Genotype A1/A2 associated with neuroleptic malignant syndrome.

scientific article published in August 2005

Improved analysis of 5-Fluorouracil and 5,6-dihydro-5-Fluorouracil by HPLC with diode array detection for determination of cellular dihydropyrimidine dehydrogenase activity and pharmacokinetic profiling

scientific article published in June 2005

In vitro and in vivo antitumour effects of novel, orally active bile acid-conjugated platinum complexes on rat hepatoma

scientific article published on 16 August 2006

Inhibition of protein farnesylation enhances the chemotherapeutic efficacy of the novel geranylgeranyltransferase inhibitor BAL9611 in human colon cancer cells.

scientific article published on June 2001

Inhibitory effect of suramin in rat models of angiogenesis in vitro and in vivo

scientific article published on 01 January 1999

Inhibitory effect of the somatostatin analogue SMS 201-995 and cytokines on the proliferation of human colon adenocarcinoma cell lines.

scientific article

Irinotecan in combination with thalidomide in patients with advanced solid tumors: a clinical study with pharmacodynamic and pharmacokinetic evaluation.

scientific article published on 6 May 2006

Irinotecan synergistically enhances the antiproliferative and proapoptotic effects of axitinib in vitro and improves its anticancer activity in vivo

scientific article published on March 2011

Lack of pharmacokinetic bioequivalence between generic and branded amoxicillin formulations. A post-marketing clinical study on healthy volunteers.

scientific article published on July 2009

Limited sampling model for the analysis of 5-fluorouracil pharmacokinetics in adjuvant chemotherapy for colorectal cancer

scientific article

Linezolid for endocarditis: a case series of 14 patients

scientific article published on 11 January 2011

Metabolism of 6-mercaptopurine in the erythrocytes, liver, and kidney of rats during multiple-dose regimens.

scientific article published in January 1999

Methods: for studying pharmacogenetic profiles of combination chemotherapeutic drugs

scientific article published on 03 June 2015

Micafungin for Candida albicans pacemaker-associated endocarditis: a case report and review of the literature

scientific article published on 17 October 2012

Oral gentamicin gut decontamination for prevention of KPC-producing Klebsiella pneumoniae infections: relevance of concomitant systemic antibiotic therapy

scientific article

Personalized medicine in Europe: not yet personal enough?

scientific article

Pharmacodynamic and pharmacogenetic angiogenesis-related markers of first-line FOLFOXIRI plus bevacizumab schedule in metastatic colorectal cancer

scientific article

Pharmacogenetic determinants of anti-cancer drug activity and toxicity.

scientific article

Pharmacokinetic and pharmacogenetic predictive markers of irinotecan activity and toxicity.

scientific article published on December 2011

Pharmacokinetic interactions between omeprazole/pantoprazole and clarithromycin in health volunteers

scientific article published in May 2004

Pharmacokinetics and pharmacodynamics of combination chemotherapy with paclitaxel and epirubicin in breast cancer patients

scientific article published on May 2002

Pharmacokinetics of azithromycin in lung tissue, bronchial washing, and plasma in patients given multiple oral doses of 500 and 1000 mg daily

scientific article published in December 2002

Pharmacokinetics, a main actor in a many-sided approach to severe 5-FU toxicity prediction

scientific article published on 5 November 2008

Population pharmacokinetic analysis of 5-FU and 5-FDHU in colorectal cancer patients: search for biomarkers associated with gastro-intestinal toxicity

scientific article published on 01 January 2012

Population pharmacokinetics of daptomycin in patients affected by severe Gram-positive infections.

scientific article published on 25 July 2013

Prognostic value of CD133 caused by mutant K-Ras and B-Raf--letter

scientific article published on 18 July 2012

Relationship between 5-fluorouracil disposition, toxicity and dihydropyrimidine dehydrogenase activity in cancer patients

scientific article published in September 2001

Relationship between plasma concentrations of 5-fluorouracil and 5-fluoro-5,6-dihydrouracil and toxicity of 5-fluorouracil infusions in cancer patients.

scientific article published in October 2002

Serotonin syndrome and the T102-->C polymorphism of the 5-HT2A receptor: a case report

scientific article published in July 2008

Severe 5-fluorouracil toxicity associated with a marked alteration of pharmacokinetics of 5-fluorouracil and its catabolite 5-fluoro-5,6-dihydrouracil: a case report.

scientific article published on December 2002

The c.480C>G polymorphism of hOCT1 influences imatinib clearance in patients affected by chronic myeloid leukemia

scientific article published on 04 March 2014

The role of thymidylate synthase as a molecular biomarker

scientific article published on 01 January 2004

Thymidylate synthase, dihydropyrimidine dehydrogenase and thymidine phosphorylase expression in colorectal cancer and normal mucosa in patients

scientific article published on 01 November 2006

Time-Dependent Pharmacokinetics of 5-Fluorouracil and Association With Treatment Tolerability in the Adjuvant Setting of Colorectal Cancer

scientific article published on 07 March 2011

Variable correlation between 6-mercaptopurine metabolites in erythrocytes and hematologic toxicity: implications for drug monitoring in children with acute lymphoblastic leukemia

scientific article published on 01 August 2000

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