List of works by Sabata Pierno

A long-term treatment with taurine prevents cardiac dysfunction in mdx mice

scientific article published on 28 September 2018

A multidisciplinary evaluation of the effectiveness of cyclosporine a in dystrophic mdx mice.

scientific article

Aging and chloride channel regulation in rat fast-twitch muscle fibres

scientific article published on 01 May 1994

Aging-associated down-regulation of ClC-1 expression in skeletal muscle: phenotypic-independent relation to the decrease of chloride conductance

scientific article published on 01 April 1999

An olive oil-derived antioxidant mixture ameliorates the age-related decline of skeletal muscle function

scientific article published on 30 May 2013

Angiotensin II modulates mouse skeletal muscle resting conductance to chloride and potassium ions and calcium homeostasis via the AT1 receptor and NADPH oxidase

scientific article

Antimyotonic effects of tocainide enantiomers on skeletal muscle fibers of congenitally myotonic goats

scientific article published on 01 March 2000

Antioxidant treatment of hindlimb-unloaded mouse counteracts fiber type transition but not atrophy of disused muscles.

scientific article published on 29 January 2010

Calcium Homeostasis Is Altered in Skeletal Muscle of Spontaneously Hypertensive Rats

scientific article published on 30 July 2014

Change of chloride ion channel conductance is an early event of slow-to-fast fibre type transition during unloading-induced muscle disuse

scientific article

Changes in Expression and Cellular Localization of Rat Skeletal Muscle ClC-1 Chloride Channel in Relation to Age, Myofiber Phenotype and PKC Modulation

scientific article published on 15 May 2020

Changes of chloride channel regulation in rat skeletal muscle during aging

scientific article published in December 1992

Changes of membrane electrical properties in extensor digitorum longus muscle from dystrophic (mdx) mice

scientific article published on 01 October 1995

Corrigendum to A long-term treatment with taurine prevents cardiac dysfunction in mdx mice [Translational Research Volume 204 (February 2019) Pages 82-99]

scientific article published on 01 September 2020

Decrease in resting calcium and calcium entry associated with slow-to-fast transition in unloaded rat soleus muscle

scientific article published on 15 August 2003

Developmental changes of membrane electrical properties of rat skeletal muscle fibers produced by prenatal exposure to carbon monoxide.

scientific article published in October 1996

Different ability of clenbuterol and salbutamol to block sodium channels predicts their therapeutic use in muscle excitability disorders

scientific article

Disuse of rat muscle in vivo reduces protein kinase C activity controlling the sarcolemma chloride conductance

scientific article

Dual Action of Mexiletine and Its Pyrroline Derivatives as Skeletal Muscle Sodium Channel Blockers and Anti-oxidant Compounds: Toward Novel Therapeutic Potential

scientific article published in January 2017

Effect of taurine depletion on excitation-contraction coupling and C1− conductance of rat skeletal muscle

scientific article published on 01 January 1996

Effects of HMG-CoA reductase inhibitors on excitation–contraction coupling of rat skeletal muscle

scientific article published on 01 January 1999

Effects of Nandrolone in the Counteraction of Skeletal Muscle Atrophy in a Mouse Model of Muscle Disuse: Molecular Biology and Functional Evaluation

scientific article (publication date: 2015)

Effects of chronic treatment with statins and fenofibrate on rat skeletal muscle: a biochemical, histological and electrophysiological study

scientific article published on 9 October 2006

Effects of pleiotrophin overexpression on mouse skeletal muscles in normal loading and in actual and simulated microgravity.

scientific article

Effects of taurine analogues on chloride channel conductance of rat skeletal muscle fibers: a structure-activity relationship investigation.

scientific article

Elucidating the Contribution of Skeletal Muscle Ion Channels to Amyotrophic Lateral Sclerosis in search of new therapeutic options

scientific article published on 28 February 2019

Enhanced dystrophic progression in mdx mice by exercise and beneficial effects of taurine and insulin-like growth factor-1.

scientific article

Fiber type-related changes in rat skeletal muscle calcium homeostasis during aging and restoration by growth hormone

scientific article

Fluvastatin and atorvastatin affect calcium homeostasis of rat skeletal muscle fibers in vivo and in vitro by impairing the sarcoplasmic reticulum/mitochondria Ca2+-release system

scientific article published on 9 February 2007

Growth hormone secretagogues exert differential effects on skeletal muscle calcium homeostasis in male rats depending on the peptidyl/nonpeptidyl structure.

scientific article published on 8 July 2013

Growth hormone secretagogues modulate the electrical and contractile properties of rat skeletal muscle through a ghrelin-specific receptor

scientific article

Growth hormone secretagogues prevent dysregulation of skeletal muscle calcium homeostasis in a rat model of cisplatin-induced cachexia.

scientific article published on 10 March 2017

Higher content of insulin-like growth factor-I in dystrophic mdx mouse: potential role in the spontaneous regeneration through an electrophysiological investigation of muscle function

scientific article published on 01 January 1999

Homologation of mexiletine alkyl chain and stereoselective blockade of skeletal muscle sodium channels

scientific article

Increased sodium channel use-dependent inhibition by a new potent analogue of tocainide greatly enhances in vivo antimyotonic activity.

scientific article published on 12 October 2016

Investigations of pharmacologic properties of the renal CLC-K1 chloride channel co-expressed with barttin by the use of 2-(p-Chlorophenoxy)propionic acid derivatives and other structurally unrelated chloride channels blockers

scientific article published in January 2004

Ion channels in muscle and cardiac hereditary diseases: from gene dysfunction to pharmacological therapy

article

Is oxidative stress a cause or consequence of disuse muscle atrophy in mice? A proteomic approach in hindlimb-unloaded mice

scientific article published on 9 October 2009

Molecular requisites for drug binding to muscle CLC-1 and renal CLC-K channel revealed by the use of phenoxy-alkyl derivatives of 2-(p-chlorophenoxy)propionic acid

scientific article

New 2-aryloxy-3-phenyl-propanoic acids as peroxisome proliferator-activated receptors alpha/gamma dual agonists with improved potency and reduced adverse effects on skeletal muscle function

scientific article

New potent mexiletine and tocainide analogues evaluated in vivo and in vitro as antimyotonic agents on the myotonic ADR mouse

scientific article

On the metabolically active form of metaglidasen: improved synthesis and investigation of its peculiar activity on peroxisome proliferator-activated receptors and skeletal muscles

scientific article

Paracrine effects of IGF-1 overexpression on the functional decline due to skeletal muscle disuse: molecular and functional evaluation in hindlimb unloaded MLC/mIgf-1 transgenic mice

scientific article

Pharmacological Interventions for the Changes of Chloride Channel Conductance of Aging Rat Skeletal Musclea

scientific article published on 01 June 1994

Phosphorylation and IGF-1-mediated dephosphorylation pathways control the activity and the pharmacological properties of skeletal muscle chloride channels

scientific article published on October 1998

Potential benefits of taurine in the prevention of skeletal muscle impairment induced by disuse in the hindlimb-unloaded rat

scientific article published on 11 October 2011

Pre-clinical trials in Duchenne dystrophy: what animal models can tell us about potential drug effectiveness

scientific article

Protein kinase C theta (PKCθ) modulates the ClC-1 chloride channel activity and skeletal muscle phenotype: a biophysical and gene expression study in mouse models lacking the PKCθ.

scientific article published on 20 March 2014

Recovery of the soleus muscle after short- and long-term disuse induced by hindlimb unloading: effects on the electrical properties and myosin heavy chain profile

scientific article published on 01 March 2005

Redox homeostasis, oxidative stress and disuse muscle atrophy.

scientific article published on 14 February 2011

Risk of Myopathy in Patients in Therapy with Statins: Identification of Biological Markers in a Pilot Study.

scientific article published on 27 July 2017

Role of tumour necrosis factor alpha, but not of cyclo-oxygenase-2-derived eicosanoids, on functional and morphological indices of dystrophic progression in mdx mice: a pharmacological approach

scientific article published in June 2007

Ryanodine channel complex stabilizer compound S48168/ARM210 as a disease modifier in dystrophin-deficient mdx mice: proof-of-concept study and independent validation of efficacy

scientific article

Safinamide's potential in treating nondystrophic myotonias: Inhibition of skeletal muscle voltage-gated sodium channels and skeletal muscle hyperexcitability in vitro and in vivo

scientific article published on 20 March 2020

Statin or fibrate chronic treatment modifies the proteomic profile of rat skeletal muscle

scientific article

Statin-induced myotoxicity is exacerbated by aging: A biophysical and molecular biology study in rats treated with atorvastatin.

scientific article published in July 2016

Statins and fenofibrate affect skeletal muscle chloride conductance in rats by differently impairing ClC-1 channel regulation and expression

scientific article

Structural requisites of 2-(p-chlorophenoxy)propionic acid analogues for activity on native rat skeletal muscle chloride conductance and on heterologously expressed CLC-1.

scientific article published on August 2003

Taurine and skeletal muscle disorders

scientific article published on January 2004

Taurine: the appeal of a safe amino acid for skeletal muscle disorders

scientific article

The alteration of calcium homeostasis in adult dystrophic mdx muscle fibers is worsened by a chronic exercise in vivo

scientific article published in November 2004

Therapeutic Approaches to Genetic Ion Channelopathies and Perspectives in Drug Discovery

scientific article

Therapeutic approaches to ion channel diseases

scientific article

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