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List of works by Peter W. Reeh

5,6-EET is released upon neuronal activity and induces mechanical pain hypersensitivity via TRPA1 on central afferent terminals

scientific article

A Randomized, Double-Blind, Placebo- and Active Comparator-Controlled Phase I Study of Analgesic/Antihyperalgesic Properties of ASP8477, a Fatty Acid Amide Hydrolase Inhibitor, in Healthy Female Subjects

scientific article published on 8 December 2017

A dominant role of acid pH in inflammatory excitation and sensitization of nociceptors in rat skin, in vitro

scientific article published on 01 May 1995

A high-threshold heat-activated channel in cultured rat dorsal root ganglion neurons resembles TRPV2 and is blocked by gadolinium

scientific article

A new paradigm to understand and treat diabetic neuropathy.

scientific article published on 12 March 2014

A technique for fast application of heated solutions of different composition to cultured neurones

article

ATP can enhance the proton-induced CGRP release through P2Y receptors and secondary PGE(2) release in isolated rat dura mater.

scientific article

Acid-induced CGRP release from the stomach does not depend on TRPV1 or ASIC3.

scientific article published on 21 January 2010

Actions of cholinergic agonists and antagonists on sensory nerve endings in rat skin, in vitro

scientific article published on 01 July 1993

Activated human platelets in plasma excite nociceptors in rat skin, in vitro

scientific article published on 01 March 1994

Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release

scientific article

Activity and connectivity changes of central projection areas revealed by functional magnetic resonance imaging in NaV1.8-deficient mice upon cold signaling.

scientific article

Amplified Cold Transduction in Native Nociceptors by M-Channel Inhibition

scientific article published on 01 October 2013

An interaction of inflammatory mediators and protons in small diameter dorsal root ganglion neurons of the rat

scientific article published on 01 March 1997

An oral TRPV1 antagonist attenuates laser radiant-heat-evoked potentials and pain ratings from UV(B)-inflamed and normal skin

scientific article

Analgesic effect of acetylsalicylic acid (ASA) versus a lithium-ASA combination: an evoked potential study employing radiant heat stimulation with a CO2 laser

scientific article

Analgesic treatment of ciguatoxin-induced cold allodynia.

scientific article published on 15 June 2013

Angiotensin II facilitates sympathetic transmission in rat hind limb circulation

scientific article published in March 1993

Beyond H2S and NO Interplay: Hydrogen Sulfide and Nitroprusside React Directly to Give Nitroxyl (HNO). A New Pharmacological Source of HNO

scientific article published on 18 February 2013

Bimodal concentration-response of nicotine involves the nicotinic acetylcholine receptor, transient receptor potential vanilloid type 1, and transient receptor potential ankyrin 1 channels in mouse trachea and sensory neurons

scientific article

Bradykinin-induced nociceptor sensitisation to heat depends on cox-1 and cox-2 in isolated rat skin

scientific article

Bradykinin-induced nociceptor sensitization to heat is mediated by cyclooxygenase products in isolated rat skin

scientific article

Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block.

scientific article published on January 2014

Ca2+ permeability of the sustained proton-induced cation current in adult rat dorsal root ganglion neurons

scientific article published on 01 November 1996

Calcitonin gene-related peptide and prostaglandin E2 but not substance P release induced by antidromic nerve stimulation from rat skin in vitro

article

Calcitonin gene-related peptide release from intact isolated dorsal root and trigeminal ganglia

scientific article published on 6 March 2008

Can receptor potentials be detected with threshold tracking in rat cutaneous nociceptive terminals?

scientific article published on 16 March 2005

Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors

scientific article

Carrageenan inflammation increases bradykinin sensitivity of rat cutaneous nociceptors

scientific article published on March 1990

Chapter 8. Tissue acidosis in nociception and pain

Chemosensitivity of fine afferents from rat skin in vitro

scientific article published in April 1990

Cigarette smoke has sensory effects through nicotinic and TRPA1 but not TRPV1 receptors on the isolated mouse trachea and larynx

scientific article

Ciguatoxins Evoke Potent CGRP Release by Activation of Voltage-Gated Sodium Channel Subtypes NaV1.9, NaV1.7 and NaV1.1.

scientific article published on 30 August 2017

Ciguatoxins activate specific cold pain pathways to elicit burning pain from cooling

scientific article

Comparison of two different preparations of ibuprofen with regard to the time course of their analgesic effect. A randomised, placebo-controlled, double-blind cross-over study using laser somatosensory evoked potentials obtained from UW-irritated sk

scientific article published in January 2004

Conditioning of histamine by bradykinin alters responses of rat nociceptor and human itch sensation

article

Crotalphine desensitizes TRPA1 ion channels to alleviate inflammatory hyperalgesia.

scientific article published on 18 July 2016

Denervation and NKI receptor block modulate stimulated CGRP and PGE2 release from rat skin

scientific article published on 01 February 2000

Differential Contribution of TRPA1, TRPV4 and TRPM8 to Colonic Nociception in Mice

scientific article

Differential effects of TRPV channel block on polymodal activation of rat cutaneous nociceptors in vitro

scientific article published on 30 April 2009

Diltiazem blocks the PH-induced excitation of rat nociceptors together with their mechanical and electrical excitability in vitro

scientific article published in January 1996

Direct evidence for functional TRPV1/TRPA1 heteromers

article

Do distinct populations of dorsal root ganglion neurons account for the sensory peptidergic innervation of the kidney?

scientific article published on 19 August 2009

Does neurogenic inflammation alter the sensitivity of unmyelinated nociceptors in the rat?

scientific article

Dose-dependent competitive block by topical acetylsalicylic and salicylic acid of low pH-induced cutaneous pain

scientific article published in January 1996

Effects of ReN1869, a CNS-available antihistamine, on capsaicin- and histamine-induced neurogenic inflammation in healthy subjects

Effects of TRPV1 receptor antagonists on stimulated iCGRP release from isolated skin of rats and TRPV1 mutant mice

scientific article

Effects of classical algogens

Effects of oxygen radicals on nociceptive afferents in the rat skin in vitro

scientific article published on 01 July 1995

Electrophysiological and Neurochemical Techniques to Investigate Sensory Neurons in Analgesia Research

scientific article published on 01 January 2010

Electrophysiological characterization of vagal afferents relevant to mucosal nociception in the rat upper oesophagus

scientific article published on 03 May 2007

Erratum: Corrigendum: Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

scholarly article published in Nature Medicine

Establishment of myelinating Schwann cells and barrier integrity between central and peripheral nervous systems depend on Sox10.

scientific article published on 15 February 2012

Excitation of cutaneous afferent nerve endings in vitro by a combination of inflammatory mediators and conditioning effect of substance P ⬇️

scientific article published on January 1, 1992

Excitation of cutaneous sensory nerve endings in the rat by 4-aminopyridine and tetraethylammonium

scientific article published on 01 January 1992

Excitatory nicotinic and desensitizing muscarinic (M2) effects on C-nociceptors in isolated rat skin.

scientific article published in May 2001

Formalin evokes calcium transients from the endoplasmatic reticulum

scientific article published on 15 April 2015

Functional and structural characterization of axonal opioid receptors as targets for analgesia

scientific article published on February 2016

H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway

scientific article

HCN2 channels account for mechanical (but not heat) hyperalgesia during long-standing inflammation

scientific article published on 10 February 2014

Heat-induced release of CGRP from isolated rat skin and effects of bradykinin and the protein kinase C activator PMA

scientific article published on 01 November 1999

Heat-resistant action potentials require TTX-resistant sodium channels Na1.8 and Na1.9

scientific article published on 03 July 2018

High concentrations of morphine sensitize and activate mouse dorsal root ganglia via TRPV1 and TRPA1 receptors

scientific article published on 16 April 2009

Human TRPA1 is a heat sensor displaying intrinsic U-shaped thermosensitivity.

scientific article published on 28 June 2016

Improved superfusion technique for rapid cooling or heating of cultured cells under patch-clamp conditions.

scientific article published on 29 August 2005

Induction and reduction of muscle tremor upon acute and repeated administration of the beta 2-agonists terbutaline, salbutamol and tulobuterol.

scientific article published on December 1987

Inflammation and hypersensitivity in the context of the sensory functions of axonal membranes: what are the molecular mechanisms?

scientific article published in January 2009

Inflammatory mediators at acidic pH activate capsaicin receptors in cultured sensory neurons from newborn rats.

scientific article published in February 1998

Inflammatory mediators do not stimulate CGRP release if prostaglandin synthesis is blocked by S(+)-flurbiprofen in isolated rat skin

scientific article published on 13 November 2003

Inflammatory mediators potentiate pain induced by experimental tissue acidosis

scientific article published in August 1996

Inflammatory pain control by blocking oxidized phospholipid-mediated TRP channel activation

scientific article

Inhibitory CB1 and activating/desensitizing TRPV1-mediated cannabinoid actions on CGRP release in rodent skin

article published in 2011

Injection pain of rocuronium and vecuronium is evoked by direct activation of nociceptive nerve endings.

scientific article

Interactions of histamine and bradykinin on polymodal C-fibres in isolated rat skin

scientific article published in January 2001

Interactions of inflammatory mediators and low pH not influenced by capsazepine in rat cutaneous nociceptors

scientific article published on 01 April 2000

Interactions of inflammatory mediators stimulating release of calcitonin gene-related peptide, substance P and prostaglandin E(2) from isolated rat skin

scientific article

Intracutaneous injections of platelets cause acute pain and protracted hyperalgesia

scientific article published on 01 May 1997

Irritant volatile anesthetics induce neurogenic inflammation through TRPA1 and TRPV1 channels in the isolated mouse trachea

scientific article published in February 2015

Lactate is a potent inhibitor of the capsaicin receptor TRPV1.

scientific article published on 9 November 2016

Local anesthetic-like inhibition of voltage-gated Na(+) channels by the partial μ-opioid receptor agonist buprenorphine

scientific article

Location of median and ulnar motornuclei in the cat

scientific article published on 01 May 1982

Location of motoneurones projecting to the cat distal forelimb. II. Median and ulnar motornuclei

scientific article published on 01 February 1986

Low pH facilitates capsaicin responses in isolated sensory neurons of the rat.

scientific article

Measurement of the analgesic effects of aspirin with a new experimental algesimetric procedure

scientific article published on 01 February 1988

Mechanisms of potassium- and capsaicin-induced axonal calcitonin gene-related peptide release: involvement of L- and T-type calcium channels and TRPV1 but not sodium channels.

scientific article published on 4 November 2007

Methylene blue induces ongoing activity in rat cutaneous primary afferents and depolarization of DRG neurons via a photosensitive mechanism.

scientific article published in November 1997

Methylglyoxal activates nociceptors through transient receptor potential channel A1 (TRPA1): a possible mechanism of metabolic neuropathies

scientific article published on 27 June 2012

Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy

scientific article

Mice and rats differ with respect to activity-dependent slowing of conduction velocity in the saphenous peripheral nerve

scientific article published on 27 February 2015

Modulation of CGRP and PGE2 release from isolated rat skin by alpha-adrenoceptors and kappa-opioid-receptors

scientific article published in July 2001

Molecular physiology of proton transduction in nociceptors

scientific article

Morphological characterization of rat Mas-related G-protein-coupled receptor C and functional analysis of agonists.

scientific article published on 4 November 2007

Morphological evidence for functional capsaicin receptor expression and calcitonin gene-related peptide exocytosis in isolated peripheral nerve axons of the mouse

scientific article

Muscarinic M2 receptors inhibit heat-induced CGRP release from isolated rat skin.

scientific article

Muscarinic M2 receptors on peripheral nerve endings: a molecular target of antinociception.

scientific article published on 3 June 2002

Muscarinic receptor subtypes mediating central and peripheral antinociception studied with muscarinic receptor knockout mice: a review

scientific article

NaV1.7 and pain: contribution of peripheral nerves

scientific article published on 24 November 2017

New mechanism underlying IL-31-induced atopic dermatitis

scientific article published on 7 February 2018

Nociceptive neurons in the rat caudal trigeminal nucleus respond to blood plasma perfusion of the subarachnoid space: the involvement of complement

scientific article

Nociceptor excitation by thermal sensitization--a hypothesis

scientific article

Norepinephrine reduces ω-conotoxin-sensitive Ca2+ currents in renal afferent neurons in rats

scientific article published on 02 November 2011

Noxious heat-induced CGRP release from rat sciatic nerve axons in vitro

scientific article published in October 2001

Opposite effects of substance P and calcitonin gene-related peptide in oxazolone colitis

scientific article published on 22 October 2011

PL13 Saying NO to H2S

Pain due to experimental acidosis in human skin: evidence for non-adapting nociceptor excitation

scientific article

Pain due to tissue acidosis: a mechanism for inflammatory and ischemic myalgia?

scientific article published on 01 April 1996

Pattern of monosynaptic Ia connections in the cat forelimb

scientific article published on 01 December 1989

Phenotyping sensory nerve endings in vitro in the mouse

scientific article

Phenotyping the function of TRPV1-expressing sensory neurons by targeted axonal silencing

scientific article published on January 2013

Photosensitization in Porphyrias and Photodynamic Therapy Involves TRPA1 and TRPV1.

scientific article published in May 2016

Photosensitization of TRPA1 and TRPV1 by 7-dehydrocholesterol: implications for the Smith-Lemli-Opitz syndrome.

scientific article published in September 2017

Plasma levels after peroral and topical ibuprofen and effects upon low pH-induced cutaneous and muscle pain

scientific article published in January 2000

Pro- and anti-inflammatory actions of ricinoleic acid: similarities and differences with capsaicin.

scientific article

Projected pain from noxious heat stimulation of an exposed peripheral nerve - A case report

scientific article published on 06 November 2008

Prostaglandin E(2) and I(2) facilitate noxious heat-induced spike discharge but not iCGRP release from rat cutaneous nociceptors

scientific article published on 10 October 2007

Protease activated receptors 1 and 4 sensitize TRPV1 in nociceptive neurones

scientific article published on 27 September 2010

Proton-induced calcitonin gene-related peptide release from rat sciatic nerve axons, in vitro, involving TRPV1.

scientific article published in August 2003

Protons selectively induce lasting excitation and sensitization to mechanical stimulation of nociceptors in rat skin, in vitro

scientific article

Pulmonary serotonin 5-HT3-sensitive afferent fibers modulate renal sympathetic nerve activity in rats

scientific article published on 01 February 1997

Quaternary Lidocaine Derivative QX-314 Activates and Permeates Human TRPV1 and TRPA1 to Produce Inhibition of Sodium Channels and Cytotoxicity

scientific article published on 9 February 2016

Rat peripheral nerve components release calcitonin gene-related peptide and prostaglandin E2 in response to noxious stimuli: evidence that nervi nervorum are nociceptors

article

Reactive dicarbonyl compounds cause Calcitonin Gene-related Peptide release and synergize with inflammatory conditions in mouse skin and peritoneum

scientific article published on 20 March 2020

Receptors, cells and circuits involved in pruritus of systemic disorders

scientific article published on 22 February 2014

Recordings From Brain Stem Neurons Responding to Chemical Stimulation of the Subarachnoid Space ⬇️

scientific article published on June 1, 1997

Reduced excitability and impaired nociception in peripheral unmyelinated fibers from Nav1.9-null mice

scientific article published on 15 September 2016

Release of calcitonin gene-related peptide from the isolated mouse heart: methodological validation of a new model

scientific article published on 18 January 2006

Release of substance P, calcitonin gene-related peptide and prostaglandin E2 from rat dura mater encephali following electrical and chemical stimulation in vitro

article

Responsiveness and functional attributes of electrically localized terminals of cutaneous C-fibers in vivo and in vitro

scientific article published on August 1992

Responsiveness of C-fiber nociceptors to punctate force-controlled stimuli in isolated rat skin: lack of modulation by inflammatory mediators and flurbiprofen

scientific article

Rises in [Ca2+]imediate capsaicin- and proton-induced heat sensitization of rat primary nociceptive neurons

scientific article published on 01 September 1999

Role of different proton-sensitive channels in releasing calcitonin gene-related peptide from isolated hearts of mutant mice

scientific article published in February 2005

Role of nitric oxide in zymosan induced paw inflammation and thermal hyperalgesia

scientific article published in February 2001

Role of sensory neurons in colitis: increasing evidence for a neuroimmune link in the gut.

scientific article published on 18 August 2010

S+ -flurbiprofen but not 5-HT1 agonists suppress basal and stimulated CGRP and PGE2 release from isolated rat dura mater

scientific article

Scratching an itch ⬇️

scientific article published on 01 February 2013

Selective excitation by capsaicin of mechano-heat sensitive nociceptors in rat skin

scientific article published in April 1988

Sensitization of nociceptive cutaneous nerve fibers from the rat's tail by noxious mechanical stimulation.

scientific article published in January 1987

Sensitization to heat through G-protein-coupled receptor pathways in the isolated sciatic mouse nerve

scientific article published on 01 June 2007

Sensitized peripheral nociception in experimental diabetes of the rat.

scientific article published on 15 September 2010

Sensory Transduction in Peripheral Nerve Axons Elicits Ectopic Action Potentials

scientific article published on 01 June 2008

Sensory and signaling mechanisms of bradykinin, eicosanoids, platelet-activating factor, and nitric oxide in peripheral nociceptors

scientific article published on October 2012

Sensory neuron sodium channel Nav1.8 is essential for pain at low temperatures

scientific article

Sensory receptors in mammalian skin in an in vitro preparation

scientific article

Sind B-Vitamine sinnvolle Zusätze zu Analgetika?

scientific article published on 01 September 1992

Sodium Channel Nav1.8 Underlies TTX-Resistant Axonal Action Potential Conduction in Somatosensory C-Fibers of Distal Cutaneous Nerves

scientific article published on 27 April 2017

Sodium channelopathies and pain

scientific article published on 26 January 2010

Soluble epoxide hydrolase limits mechanical hyperalgesia during inflammation

scientific article published on 04 October 2011

Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage

scientific article published on 10 May 2010

Sox10 is required for Schwann-cell homeostasis and myelin maintenance in the adult peripheral nerve

scientific article published on 12 April 2011

Stable analogues of cyclic AMP but not cyclic GMP sensitize unmyelinated primary afferents in rat skin to heat stimulation but not to inflammatory mediators, in vitro

scientific article published in September 1996

Stimulated prostaglandin E2 release from rat skin, in vitro.

scientific article published on January 1998

Stimulated release of calcitonin gene-related peptide from the human right atrium in patients with and without diabetes mellitus

article

Streptozotocin Stimulates the Ion Channel TRPA1 Directly: INVOLVEMENT OF PEROXYNITRITE

scientific article published on 22 April 2015

Substance P, calcitonin gene related peptide and PGE2 co-released from the mouse colon: a new model to study nociceptive and inflammatory responses in viscera, in vitro

scientific article published in September 2001

Sustained graded pain and hyperalgesia from harmless experimental tissue acidosis in human skin

scientific article

Sustained sensitization and recruitment of rat cutaneous nociceptors by bradykinin and a novel theory of its excitatory action

scientific article published on 01 April 2001

Systemic desensitization through TRPA1 channels by capsazepine and mustard oil - a novel strategy against inflammation and pain

scientific article published on 30 June 2016

TREK-1, a K+ channel involved in polymodal pain perception

scientific article published on 4 May 2006

TRPA1 and Substance P Mediate Colitis in Mice

scientific article published on 18 July 2011

TRPA1 and TRPV1 Antagonists Do Not Inhibit Human Acidosis-Induced Pain.

scientific article

TRPA1 and TRPV1 are differentially involved in heat nociception of mice

scientific article published on 29 May 2013

TRPA1 and TRPV1 are required for lidocaine-evoked calcium influx and neuropeptide release but not cytotoxicity in mouse sensory neurons

scientific article published on 15 November 2017

TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins.

scientific article

TRPA1-mediated nociception: Response to letter by Fischer et al

scientific article published on 01 August 2008

TRPV1 controls acid- and heat-induced calcitonin gene-related peptide release and sensitization by bradykinin in the isolated mouse trachea

scientific article published on 17 April 2009

TRPV1, TRPA1, and CB1 in the isolated vagus nerve – Axonal chemosensitivity and control of neuropeptide release

scientific article published on 24 August 2011

Taurolidine and congeners activate hTRPA1 but not hTRPV1 channels and stimulate CGRP release from mouse tracheal sensory nerves

scientific article published on February 2016

The TRPV1/2/3 activator 2-aminoethoxydiphenyl borate sensitizes native nociceptive neurons to heat in wildtype but not TRPV1 deficient mice

scientific article published on 13 September 2005

The anti-diabetic drug glibenclamide is an agonist of the transient receptor potential Ankyrin 1 (TRPA1) ion channel

The effect of 4-aminopyridine on action potential shape and firing pattern of rat dorsal root ganglion neurones

scientific article published on 01 January 1989

The effect of carrageenan-induced inflammation on the sensitivity of unmyelinated skin nociceptors in the rat

scientific article published on 01 June 1987

The effects of excessive heat on heat-activated membrane currents in cultured dorsal root ganglia neurons from neonatal rat.

scientific article published on February 2002

The general anesthetic propofol excites nociceptors by activating TRPV1 and TRPA1 rather than GABAA receptors

scientific article published on 7 September 2010

The interphase of the formalin test

scientific article published on 27 November 2013

The mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception

scientific article

The molecular basis for species-specific activation of human TRPA1 protein by protons involves poorly conserved residues within transmembrane domains 5 and 6.

scientific article published on 24 May 2013

The nociceptor sensitization by bradykinin does not depend on sympathetic neurons.

scientific article published in January 1992

The pH response of rat cutaneous nociceptors correlates with extracellular [Na+] and is increased under amiloride

scientific article published on 01 August 1999

The phospholipase C inhibitor U73122 is a potent agonist of the polymodal transient receptor potential ankyrin type 1 (TRPA1) receptor channel

scientific article published on 03 September 2019

The prokineticin Bv8 sensitizes cutaneous terminals of female mice to heat.

scientific article

The proximodistal aggravation of colitis depends on substance P released from TRPV1-expressing sensory neurons

scientific article published on 12 November 2011

The roles of TRPV1, TRPA1 and TRPM8 channels in chemical and thermal sensitivity of the mouse oral mucosa

scientific article

The tetrodotoxin-resistant Na+ channel Na (v)1.8 reduces the potency of local anesthetics in blocking C-fiber nociceptors

scientific article published on 23 February 2010

The vanilloid receptor TRPV1 is activated and sensitized by local anesthetics in rodent sensory neurons

scientific journal article

Tonic Postganglionic Sympathetic Inhibition Induced by Afferent Renal Nerves?

scientific article published on 03 January 2012

Topical acetylsalicylic, salicylic acid and indomethacin suppress pain from experimental tissue acidosis in human skin

scientific article published on September 1995

Transient opening of the perineurial barrier for analgesic drug delivery

scientific journal article

Transient receptor potential melastatin 8 ion channel in macrophages modulates colitis through a balance-shift in TNF-alpha and interleukin-10 production

scientific article published on 16 March 2016

Unresponsive afferent nerve fibres in the sural nerve of the rat ⬇️

scientific article published on 01 April 1991

Use dependence of peripheral nociceptive conduction in the absence of tetrodotoxin-resistant sodium channel subtypes

scientific article

Variable sensitivity to noxious heat is mediated by differential expression of the CGRP gene

scientific journal article

Verleihung des Förderpreises für Schmerzforschung am 14.11.1992 in Heidelberg

scientific article published on 01 March 1993

Vitamin B complex attenuated heat hyperalgesia following infraorbital nerve constriction in rats and reduced capsaicin in vivo and in vitro effects

scientific article published on 3 June 2015

Why cooling is beneficial: non-linear temperature-dependency of stimulated iCGRP release from isolated rat skin

scientific article

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