List of works - Tom Hearn

ALMS1 and Alström syndrome: a recessive form of metabolic, neurosensory and cardiac deficits

scientific article published on 12 November 2018

Centriolar association of ALMS1 and likely centrosomal functions of the ALMS motif-containing proteins C10orf90 and KIAA1731

scientific article

Charge-tagging liquid chromatography-mass spectrometry methodology targeting oxysterol diastereoisomers.

scientific article published on 11 April 2017

Cholesterolomics: An update

scientific article

Current trends in oxysterol research

scientific article

Development of the human pancreas from foregut to endocrine commitment.

scientific article published on 29 April 2013

Elevated oxysterol levels in human and mouse livers reflect nonalcoholic steatohepatitis

scientific article published on 21 May 2019

Evidence for centriolar satellite localization of CDK1 and cyclin B2.

scientific article published on 2 May 2013

Evidence for reciliation of RPE1 cells in late G1 phase, and ciliary localisation of cyclin B1.

scientific article published on 11 August 2013

Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10p

scientific article

Identification of unusual oxysterols and bile acids with 7-oxo or 3β,5α,6β-trihydroxy functions in human plasma by charge-tagging mass spectrometry with multistage fragmentation.

scientific article published on 6 April 2018

In vitro expression of NGN3 identifies RAB3B as the predominant Ras-associated GTP-binding protein 3 family member in human islets

scientific article

Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders

scientific article published on 19 April 2019

Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alström syndrome

scientific article

Narrowing the critical region within 11q24-qter for hypoplastic left heart and identification of a candidate gene, JAM3, expressed during cardiogenesis

scientific article (publication date: April 2002)

Nek2 localises to the distal portion of the mother centriole/basal body and is required for timely cilium disassembly at the G2/M transition.

scientific article

Sequences flanking the centromere of human chromosome 10 are a complex patchwork of arm-specific sequences, stable duplications and unstable sequences with homologies to telomeric and other centromeric locations

scientific article published on 01 February 1999

Spectrum of ALMS1 variants and evaluation of genotype-phenotype correlations in Alström syndrome

scientific article published in November 2007

Subcellular localization of ALMS1 supports involvement of centrosome and basal body dysfunction in the pathogenesis of obesity, insulin resistance, and type 2 diabetes

scientific article

Transcriptional regulation of the Alström syndrome gene ALMS1 by members of the RFX family and Sp1

scientific article

List of works by Tom Hearn

ALMS1 and Alström syndrome: a recessive form of metabolic, neurosensory and cardiac deficits

Centriolar association of ALMS1 and likely centrosomal functions of the ALMS motif-containing proteins C10orf90 and KIAA1731

Charge-tagging liquid chromatography-mass spectrometry methodology targeting oxysterol diastereoisomers.

Cholesterolomics: An update

Current trends in oxysterol research

Development of the human pancreas from foregut to endocrine commitment.

Elevated oxysterol levels in human and mouse livers reflect nonalcoholic steatohepatitis

Evidence for centriolar satellite localization of CDK1 and cyclin B2.

Evidence for reciliation of RPE1 cells in late G1 phase, and ciliary localisation of cyclin B1.

Genomic sequence and transcriptional profile of the boundary between pericentromeric satellites and genes on human chromosome arm 10p

Identification of unusual oxysterols and bile acids with 7-oxo or 3β,5α,6β-trihydroxy functions in human plasma by charge-tagging mass spectrometry with multistage fragmentation.

In vitro expression of NGN3 identifies RAB3B as the predominant Ras-associated GTP-binding protein 3 family member in human islets

Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders

Mutation of ALMS1, a large gene with a tandem repeat encoding 47 amino acids, causes Alström syndrome

Narrowing the critical region within 11q24-qter for hypoplastic left heart and identification of a candidate gene, JAM3, expressed during cardiogenesis

Nek2 localises to the distal portion of the mother centriole/basal body and is required for timely cilium disassembly at the G2/M transition.

Sequences flanking the centromere of human chromosome 10 are a complex patchwork of arm-specific sequences, stable duplications and unstable sequences with homologies to telomeric and other centromeric locations

Spectrum of ALMS1 variants and evaluation of genotype-phenotype correlations in Alström syndrome

Subcellular localization of ALMS1 supports involvement of centrosome and basal body dysfunction in the pathogenesis of obesity, insulin resistance, and type 2 diabetes

Transcriptional regulation of the Alström syndrome gene ALMS1 by members of the RFX family and Sp1