List of works by Ben J. Gu

A 5' intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1-2% of the Caucasian population.

scientific article

A Glu-496 to Ala polymorphism leads to loss of function of the human P2X7 receptor

scientific article (publication date: 6 April 2001)

A loss-of-function polymorphism in the human P2X4 receptor is associated with increased pulse pressure.

scientific article

A new role for the P2X7 receptor: a scavenger receptor for bacteria and apoptotic cells in the absence of serum and extracellular ATP

scientific article

A quantitative method for measuring innate phagocytosis by human monocytes using real-time flow cytometry

scientific article published on 16 October 2013

A quantitative method for routine measurement of cell surface P2X7 receptor function in leucocyte subsets by two-colour time-resolved flow cytometry

scientific article published on 26 June 2007

A rare functional haplotype of the P2RX4 and P2RX7 genes leads to loss of innate phagocytosis and confers increased risk of age-related macular degeneration

scientific article published on 9 January 2013

An Arg307 to Gln polymorphism within the ATP-binding site causes loss of function of the human P2X7 receptor.

scientific article

Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome.

scientific article published on 02 June 2013

Extracellular ATP dissociates nonmuscle myosin from P2X(7) complex: this dissociation regulates P2X(7) pore formation.

scientific article

Functional significance of P2RX7 polymorphisms associated with affective mood disorders

scientific article published on 11 May 2010

Genetics of the P2X7 receptor and human disease.

scientific article published on 25 March 2009

Innate phagocytosis by peripheral blood monocytes is altered in Alzheimer's disease

scientific article

Non-synonymous polymorphisms in the P2RX ( 4 ) are related to bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

scientific article published on 10 November 2012

P2X(7) is a scavenger receptor for apoptotic cells in the absence of its ligand, extracellular ATP.

scientific article

P2X7 Receptors Regulate Phagocytosis and Proliferation in Adult Hippocampal and SVZ Neural Progenitor Cells: Implications for Inflammation in Neurogenesis

scientific article published on 17 September 2018

P2X7 as a scavenger receptor for innate phagocytosis in the brain

scientific article published on 05 October 2018

P2X7 receptor-mediated scavenger activity of mononuclear phagocytes toward non-opsonized particles and apoptotic cells is inhibited by serum glycoproteins but remains active in cerebrospinal fluid

scientific article

P2X7 receptors mediate innate phagocytosis by human neural precursor cells and neuroblasts.

scientific article published in February 2015

P2Y(11) receptor expression by human lymphocytes: evidence for two cAMP-linked purinoceptors

scientific article published in August 2001

Point mutations confer loss of ATP-induced human P2X(7) receptor function

scientific article (publication date: 13 February 2002)

Rapid ATP-induced release of matrix metalloproteinase 9 is mediated by the P2X7 receptor

scientific article published on 2 March 2006

Shear stress modulates endothelial KLF2 through activation of P2X4.

scientific article published on 8 January 2015

Specific detection of non-functional human P2X(7) receptors in HEK293 cells and B-lymphocytes

scientific article (publication date: 13 March 2003)

Topographical Distribution and Phenotype of Resident Meibomian Gland Orifice Immune Cells (MOICs) in Mice and the Effects of Topical Benzalkonium Chloride (BAK)

scientific article published in 2022

Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1beta secretion

scientific article published in April 2010

Paulina is supported by:

About Paulina

Help