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Authors whose works are in public domain in at least one jurisdiction

List of works by Patrick Doherty

A complementary peptide approach applied to the design of novel semaphorin/neuropilin antagonists

scientific article published on 01 March 2005

A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner

scientific article

A dimeric version of the short N-cadherin binding motif HAVDI promotes neuronal cell survival by activating an N-cadherin/fibroblast growth factor receptor signalling cascade

scientific article

A novel live cell assay to measure diacylglycerol lipase α activity

scientific article published on 24 March 2016

A retinoic acid receptor beta agonist (CD2019) overcomes inhibition of axonal outgrowth via phosphoinositide 3-kinase signalling in the injured adult spinal cord

scientific article published on 2 October 2009

Amphotericin B, identified from a natural product screen, antagonizes CNS inhibitors to promote axon growth via activation of an Akt pathway in neurons

scientific article published on 25 March 2010

Amyloid precursor protein (APP) contributes to pathology in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis

scientific article published on 07 June 2012

An inactive pool of GSK-3 at the leading edge of growth cones is implicated in Semaphorin 3A signaling.

scientific article published on 15 April 2002

Assay and Inhibition of the Purified Catalytic Domain of Diacylglycerol Lipase Beta

scientific article published on 04 May 2016

BDNF regulates neuronal sensitivity to endocannabinoids

scientific article published on 8 October 2009

Cannabinoid receptor, CB1, expression follows neuronal differentiation in the early chick embryo

scientific article published in September 2004

Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain

scientific article

DAGL-dependent endocannabinoid signalling: roles in axonal pathfinding, synaptic plasticity and adult neurogenesis.

scientific article

Dimeric versions of two short N-cadherin binding motifs (HAVDI and INPISG) function as N-cadherin agonists

scientific article published on 28 November 2001

Direct measurement of local raised subplasmalemmal calcium concentrations in growth cones advancing on an N-cadherin substrate

scientific article published in June 2002

Down-regulation of diacylglycerol lipase-alpha during neural stem cell differentiation: identification of elements that regulate transcription

scientific article published on March 2010

Drebrin regulates neuroblast migration in the postnatal mammalian brain

scientific article published on 6 May 2015

Endocannabinoid Turnover

scientific article published on 25 May 2017

Endocannabinoids regulate the migration of subventricular zone-derived neuroblasts in the postnatal brain.

scientific article published on March 2011

Fascin regulates the migration of subventricular zone-derived neuroblasts in the postnatal brain

scientific article published on July 2013

Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists

scientific journal article

Identification of an N-cadherin motif that can interact with the fibroblast growth factor receptor and is required for axonal growth.

scientific article

In vivo postnatal electroporation and time-lapse imaging of neuroblast migration in mouse acute brain slices

scientific article

Inter-residue distances derived from fold contact propensities correlate with evolutionary substitution costs

scientific article

Loss of retrograde endocannabinoid signaling and reduced adult neurogenesis in diacylglycerol lipase knock-out mice

scientific journal article

Myostatin inhibition slows muscle atrophy in rodent models of amyotrophic lateral sclerosis

scientific article published on 11 July 2006

N-cadherin influences migration of oligodendrocytes on astrocyte monolayers

scientific article published on 01 March 2000

Nanoscale Structural Plasticity of the Active Zone Matrix Modulates Presynaptic Function.

scientific article published on March 2017

Neuroglian and FasciclinII can promote neurite outgrowth via the FGF receptor Heartless

scientific article published on June 2004

Nucleofection of rodent neuroblasts to study neuroblast migration in vitro.

scientific article

Overcoming amino-Nogo-induced inhibition of cell spreading and neurite outgrowth by 12-O-tetradecanoylphorbol-13-acetate-type tumor promoters.

scientific article published on 15 December 2009

Overcoming the inhibitors of myelin with a novel neurotrophin strategy

scientific article published on 30 November 2004

Polysialyltransferase ST8Sia II (STX) polysialylates all of the major isoforms of NCAM and facilitates neurite outgrowth.

scientific article published on March 2001

RalA promotes a direct exocyst-Par6 interaction to regulate polarity in neuronal development

scientific article

Receptors for myelin inhibitors: Structures and therapeutic opportunities

scientific article published on 18 July 2009

Regional effects of endocannabinoid, BDNF and FGF receptor signalling on neuroblast motility and guidance along the rostral migratory stream

scientific article

Regulated endosomal trafficking of Diacylglycerol lipase alpha (DAGLα) generates distinct cellular pools; implications for endocannabinoid signaling

scientific article published on 2 September 2016

Regulation of PI3K signalling by the phosphatidylinositol transfer protein PITPalpha during axonal extension in hippocampal neurons

scientific article published on 19 February 2008

Robo1 and Robo2 are homophilic binding molecules that promote axonal growth

scientific article

Targeted lipidomics in Drosophila melanogaster identifies novel 2-monoacylglycerols and N-acyl amides

scientific article published in 2013

The COX-2 inhibitors, meloxicam and nimesulide, suppress neurogenesis in the adult mouse brain

scientific article

The FGF receptor uses the endocannabinoid signaling system to couple to an axonal growth response

scientific article published on 10 February 2003

The FGFR1 inhibitor PD 173074 selectively and potently antagonizes FGF-2 neurotrophic and neurotropic effects.

scientific article published on October 2000

The diacylglycerol lipases: structure, regulation and roles in and beyond endocannabinoid signalling

scientific article published on December 2012

The endocannabinoid receptor, CB1, is required for normal axonal growth and fasciculation

scientific article published on 10 March 2008

The fibroblast growth factor receptor acid box is essential for interactions with N-cadherin and all of the major isoforms of neural cell adhesion molecule

scientific article published on 27 September 2006

The generation of localized calcium rises mediated by cell adhesion molecules and their role in neuronal growth cone motility.

scientific article

The molecular basis of the cooperation between EGF, FGF and eCB receptors in the regulation of neural stem cell function

scientific article

The molecular interplay between endocannabinoid and neurotrophin signals in the nervous system and beyond

scientific article published on February 2014

Transcriptional basis for the inhibition of neural stem cell proliferation and migration by the TGFβ-family member GDF11

scientific article published on 7 November 2013

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