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List of works by Shashi Bhushan

2-Anilinonicotinyl linked 2-aminobenzothiazoles and [1,2,4]triazolo[1,5-b] [1,2,4]benzothiadiazine conjugates as potential mitochondrial apoptotic inducers

scientific article

3-(Benzo[d][1,3]dioxol-5-ylamino)-N-(4-fluorophenyl)thiophene-2-carboxamide overcomes cancer chemoresistance via inhibition of angiogenesis and P-glycoprotein efflux pump activity

scientific article

6-Aryl substituted 4-(4-cyanomethyl) phenylamino quinazolines as a new class of isoform-selective PI3K-alpha inhibitors

scientific article published on 12 July 2016

A chromatography-free isolation of rohitukine from leaves of Dysoxylum binectariferum: Evaluation for in vitro cytotoxicity, Cdk inhibition and physicochemical properties

scientific article published on 16 June 2016

A complex between the Zika virion and the Fab of a broadly cross-reactive neutralizing monoclonal antibody revealed by cryo-EM and single particle analysis at 4.1 Å resolution

scientific article published on 17 June 2020

A novel cyano derivative of 11-keto-β-boswellic acid causes apoptotic death by disrupting PI3K/AKT/Hsp-90 cascade, mitochondrial integrity, and other cell survival signaling events in HL-60 cells

scientific article published on 12 July 2011

A novel quinazolinone chalcone derivative induces mitochondrial dependent apoptosis and inhibits PI3K/Akt/mTOR signaling pathway in human colon cancer HCT-116 cells

scientific article published on 23 November 2015

A novel quinazolinone derivative induces cytochrome c interdependent apoptosis and autophagy in human leukemia MOLT-4 cells

scientific article published on 12 August 2014

A novel stereo bioactive metabolite isolated from an endophytic fungus induces caspase dependent apoptosis and STAT-3 inhibition in human leukemia cells

scientific article published on 17 August 2015

Activation of caspases and poly (ADP-ribose) polymerase cleavage to induce apoptosis in leukemia HL-60 cells by Inula racemosa

scientific article published on 17 June 2010

AhpC of the mycobacterial antioxidant defense system and its interaction with its reducing partner Thioredoxin-C.

scientific article published on 11 July 2017

Anticancer activity, toxicity and pharmacokinetic profile of an indanone derivative

scientific article

Apple phenolics as nutraceuticals: assessment, analysis and application

scientific article

Atomic structure and enzymatic insights into the vancomycin-resistant Enterococcus faecalis (V583) alkylhydroperoxide reductase subunit C.

scientific article

Beta3-adrenoreceptor stimulation ameliorates myocardial ischemia-reperfusion injury via endothelial nitric oxide synthase and neuronal nitric oxide synthase activation

scientific article published on December 2011

Bioactive metabolites from an endophytic Cryptosporiopsis sp. inhabiting Clidemia hirta ⬇️

scientific article published on July 17, 2013

Biotechnological approaches to the production of shikonins: a critical review with recent updates

scientific article

Chitosan-Stearic Acid Based Polymeric Micelles for the Effective Delivery of Tamoxifen: Cytotoxic and Pharmacokinetic Evaluation

scientific article published on 10 June 2016

Choline Diet and Its Gut Microbe-Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload-Induced Heart Failure

scientific article published on 23 December 2015

Conjugation of Docetaxel with Multiwalled Carbon Nanotubes and Codelivery with Piperine: Implications on Pharmacokinetic Profile and Anticancer Activity

scientific article

Controllable Hydrogen Sulfide Donors and Their Activity against Myocardial Ischemia-Reperfusion Injury ⬇️

scientific article published on April 16, 2013

Correcting for AFM tip induced topography convolutions in protein–DNA samples ⬇️

scientific article published on July 17, 2012

Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-A resolution

scientific article

Cryo-EM structure of the large subunit of the spinach chloroplast ribosome

scientific article

Cryo-electron microscopic structure of SecA protein bound to the 70S ribosome

scientific article published on 17 January 2014

Degradation of the amyloid beta-protein by the novel mitochondrial peptidasome, PreP

scientific article

Design and synthesis of a new class of cryptophycins based tubulin inhibitors

scientific article

Development and Evaluation of Novel Surfactant-Based Elastic Vesicular System for Ocular Delivery of Fluconazole ⬇️

scientific article published on June 13, 2012

Dexmedetomidine as an Anesthetic Adjuvant in Intracranial Surgery

scientific article

Dextran-PLGA-loaded docetaxel micelles with enhanced cytotoxicity and better pharmacokinetic profile

scientific article published on 29 March 2016

Discovery of a marine-derived bis-indole alkaloid fascaplysin, as a new class of potent P-glycoprotein inducer and establishment of its structure-activity relationship

scientific article published on 31 October 2015

Disruption of the PI3K/AKT/mTOR signaling cascade and induction of apoptosis in HL-60 cells by an essential oil from Monarda citriodora

scientific article

Dual targeting and function of a protease in mitochondria and chloroplasts.

scientific article

Enhanced anticancer potential of encapsulated solid lipid nanoparticles of TPD: a novel triterpenediol from Boswellia serrata

scientific article published on 13 December 2012

Evaluation of bishexadecyltrimethyl ammonium palladium tetrachloride based dual functional colloidal carrier as an antimicrobial and anticancer agent

scientific article published on 10 March 2016

Fruits and barks extracts of Zanthozyllum heitzii a spice from Cameroon induce mitochondrial dependent apoptosis and Go/G1 phase arrest in human leukemia HL-60 cells

scientific article

Functional Evolution in Orthologous Cell-encoded RNA-dependent RNA Polymerases

scientific article published on 23 February 2016

Glycyrrhizic acid prevents ultraviolet-B-induced photodamage: a role for mitogen-activated protein kinases, nuclear factor kappa B and mitochondrial apoptotic pathway

scientific article published on 2 February 2016

Green synthesis and anticancer potential of chalcone linked-1,2,3-triazoles

scientific article

Hydrogen sulfide attenuates cardiac dysfunction after heart failure via induction of angiogenesis

scientific article published on 28 June 2013

H₂S protects against pressure overload-induced heart failure via upregulation of endothelial nitric oxide synthase

scientific article published on 7 February 2013

Identification and characterization of multiple rubisco activases in chemoautotrophic bacteria

scientific article published on 16 November 2015

Immune modulation and apoptosis induction: Two sides of antitumoural activity of a standardised herbal formulation of Withania somnifera

scientific article published on 5 March 2009

In Vitro Anticancer Activities of Anogeissus latifolia, Terminalia bellerica, Acacia catechu and Moringa oleiferna Indian Plants

scientific article published on January 2015

In vitro cytotoxic potential of Polyalthia longifolia on human cancer cell lines and induction of apoptosis through mitochondrial-dependent pathway in HL-60 cells

scientific article

Induction of mitochondrial dependent apoptosis and cell cycle arrest in human promyelocytic leukemia HL-60 cells by an extract from Dorstenia psilurus: a spice from Cameroon

scientific article

Induction of mitochondrial-dependent apoptosis by an essential oil from Tanacetum gracile

scientific article published on 10 April 2008

Insights into the mechanism and regulation of the CbbQO-type Rubisco activase, a MoxR AAA+ ATPase

scientific article published on 17 December 2019

Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome

scientific article

Multiple Pharmacological Properties of a Novel Parthenin Analog P16 as Evident by its Cytostatic and Antiangiogenic Potential Against Pancreatic Adenocarcinoma PANC -1 Cells

scientific article published on 24 August 2015

Natural antioxidants synergistically enhance the anticancer potential of AP9-cd, a novel lignan composition from Cedrus deodara in human leukemia HL-60 cells ⬇️

scientific article published on October 7, 2010

Nitrite Therapy Ameliorates Myocardial Dysfunction via H2S and Nuclear Factor-Erythroid 2-Related Factor 2 (Nrf2)-Dependent Signaling in Chronic Heart Failure

scientific article published on 29 July 2016

Nitrite therapy improves left ventricular function during heart failure via restoration of nitric oxide-mediated cytoprotective signaling

scientific article published on 05 March 2014

Rational Engineering and Characterization of an mAb that Neutralizes Zika Virus by Targeting a Mutationally Constrained Quaternary Epitope.

scientific article

SecM-stalled ribosomes adopt an altered geometry at the peptidyl transferase center

scientific article

Selective β2-adrenoreceptor stimulation attenuates myocardial cell death and preserves cardiac function after ischemia-reperfusion injury

scientific article

Structural Basis for Linezolid Binding Site Rearrangement in the Staphylococcus aureus Ribosome

scientific article

Structural basis for translational stalling by human cytomegalovirus and fungal arginine attenuator peptide

scientific article

Structural basis of RIP2 activation and signaling

scientific article published in Nature Communications

Structure and function of Mycobacterium-specific components of F-ATP synthase subunits α and ε

scientific article published on 17 October 2018

Structure and subunit arrangement of Mycobacterial F1FO ATP synthase and novel features of the unique mycobacterial subunit δ

scientific article published on 24 May 2019

Structure of BipA in GTP form bound to the ratcheted ribosome

scientific article

Structure of Monomeric Yeast and Mammalian Sec61 Complexes Interacting with the Translating Ribosome

scientific article

Structure of the GTP Form of Elongation Factor 4 (EF4) Bound to the Ribosome

scientific article published on 02 May 2016

Structures of Mycobacterium smegmatis 70S ribosomes in complex with HPF, tmRNA, and P-tRNA

scientific article published in Scientific Reports

Studies on tamoxifen encapsulated in lipid vesicles: effect on the growth of human breast cancer MCF-7 cells

scientific article

Synthesis and anti-proliferative activities of new derivatives of embelin

scientific article published on September 2014

Synthesis of 5-substituted-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one analogs and their biological evaluation as anticancer agents: mTOR inhibitors

scientific article published on 18 April 2014

Synthesis, antiproliferative and apoptosis-inducing activity of thiazolo[5,4-d]pyrimidines

scientific article published on 22 October 2013

Tamoxifen-encapsulated vesicular systems: cytotoxicity evaluation in human epidermal keratinocyte cell line

scientific article

The NHLBI-sponsored Consortium for preclinicAl assESsment of cARdioprotective therapies (CAESAR): a new paradigm for rigorous, accurate, and reproducible evaluation of putative infarct-sparing interventions in mice, rabbits, and pigs

scientific article

The anti-angiogenic and cytotoxic effects of the boswellic acid analog BA145 are potentiated by autophagy inhibitors

scientific article

The augmented anticancer potential of AP9-cd loaded solid lipid nanoparticles in human leukemia Molt-4 cells and experimental tumor

scientific article published on 24 November 2015

The closed structure of presequence protease PreP forms a unique 10,000 Angstroms3 chamber for proteolysis

scientific article

The polysulfide diallyl trisulfide protects the ischemic myocardium by preservation of endogenous hydrogen sulfide and increasing nitric oxide bioavailability ⬇️

scientific article published on March 30, 2012

The stimulating role of subunit F in ATPase activity inside the A1-complex of the Methanosarcina mazei Gö1 A1AO ATP synthase

scientific article published on 9 December 2015

The structural features of Acetobacterium woodii F-ATP synthase reveal the importance of the unique subunit γ-loop in Na+ translocation and ATP synthesis

scientific article published on 12 March 2019

The synthetic tryptanthrin analogue suppresses STAT3 signaling and induces caspase dependent apoptosis via ERK up regulation in human leukemia HL-60 cells

scientific article

Two novel mitochondrial and chloroplastic targeting-peptide-degrading peptidasomes in A. thaliana, AtPreP1 and AtPreP2.

scientific article published on October 2006

Unique localization of the plastid-specific ribosomal proteins in the chloroplast ribosome small subunit provides mechanistic insights into the chloroplastic translation

scientific article published on 5 June 2017

Unique structural features of the Mycobacterium ribosome

scientific article published on 10 December 2019

alpha-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel

scientific article

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