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List of works by Sylvie Fournel-Gigleux

'Click'-xylosides as initiators of the biosynthesis of glycosaminoglycans: Comparison of mono-xylosides with xylobiosides

scientific article published on 12 September 2016

Defective initiation of glycosaminoglycan synthesis due to B3GALT6 mutations causes a pleiotropic Ehlers-Danlos-syndrome-like connective tissue disorder

scientific article

Epigenetics: methylation-associated repression of heparan sulfate 3-O-sulfotransferase gene expression contributes to the invasive phenotype of H-EMC-SS chondrosarcoma cells

scientific article published on 7 October 2009

Evidence of calcium-dependent pathway in the regulation of human beta1,3-glucuronosyltransferase-1 (GlcAT-I) gene expression: a key enzyme in proteoglycan synthesis

scientific article

Identification of key functional residues in the active site of human {beta}1,4-galactosyltransferase 7: a major enzyme in the glycosaminoglycan synthesis pathway

scientific article published on 14 September 2010

Insights on membrane topology and structure/function of UDP-glucuronosyltransferases

scientific article published on February 2010

Modulation of xylosyltransferase I expression provides a mechanism regulating glycosaminoglycan chain synthesis during cartilage destruction and repair

scientific journal article

Phosphorylation and sulfation of oligosaccharide substrates critically influence the activity of human beta1,4-galactosyltransferase 7 (GalT-I) and beta1,3-glucuronosyltransferase I (GlcAT-I) involved in the biosynthesis of the glycosaminoglycan-pro

scientific article

Phylogenetic and mutational analyses reveal key residues for UDP-glucuronic acid binding and activity of beta1,3-glucuronosyltransferase I (GlcAT-I)

scientific article

Probing the acceptor active site organization of the human recombinant β1,4-galactosyltransferase 7 and design of xyloside-based inhibitors

scientific article published on 7 January 2015

Recent structures, evolution and mechanisms of glycosyltransferases ⬇️

scientific article published on July 19, 2012

Structure of UDP-glucuronosyltransferases in membranes

scientific article

Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7. Identification of a critical aromatic amino acid residue at position 33

scientific article

Targeting of Proteoglycan Synthesis Pathway: A New Strategy to Counteract Excessive Matrix Proteoglycan Deposition and Transforming Growth Factor-β1-Induced Fibrotic Phenotype in Lung Fibroblasts

scientific article

The 2017 international classification of the Ehlers-Danlos syndromes

scientific article published on March 2017

The Ehlers-Danlos syndromes, rare types

scientific article published on March 2017

The UDP-glucuronosyltransferases of the blood-brain barrier: their role in drug metabolism and detoxication

scientific article

The donor substrate specificity of the human beta 1,3-glucuronosyltransferase I toward UDP-glucuronic acid is determined by two crucial histidine and arginine residues

scientific article (publication date: 12 July 2002)

The functional glycosyltransferase signature sequence of the human beta 1,3-glucuronosyltransferase is a XDD motif

scientific article

The human UDP-glucuronosyltransferases: structural aspects and drug glucuronidation

scientific article published on November 2003

The importance of cysteine 126 in the human liver UDP-glucuronosyltransferase UGT1A6.

scientific article

Xylosyltransferase-I regulates glycosaminoglycan synthesis during the pathogenic process of human osteoarthritis

scientific article

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