List of works by Robson Coutinho-Silva

A Dual Role for P2X7 Receptor during Porphyromonas gingivalis Infection

scientific article

A cation non-selective channel induced by extracellular ATP in macrophages and phagocytic cells of the thymic reticulum

scientific article published on 01 January 1996

Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation.

scientific article published on February 2006

Activation of the P2X(7) receptor triggers the elimination of Toxoplasma gondii tachyzoites from infected macrophages

scientific article published on 16 March 2010

Adenine Nucleotides Control Proliferation In Vivo of Rat Retinal Progenitors by P2Y1 Receptor.

scientific article

C terminus of the P2X7 receptor: treasure hunting.

scientific article published on 27 January 2011

Cellular alarms and whispers contribute to the polyphonic melody of danger signals required for immunity

scientific article published on 23 October 2012

Changes in expression of P2 receptors in rat and mouse pancreas during development and ageing

scientific article published on 10 October 2001

Changes in expression of P2X7 receptors in NOD mouse pancreas during the development of diabetes

scientific article published on 01 March 2007

Characterization of ATP-induced cell death in the GL261 mouse glioma

scientific article

Characterization of P2Z purinergic receptors on phagocytic cells of the thymic reticulum in culture

scientific article published in April 1996

Characterizing the presence and sensitivity of the P2X7 receptor in different compartments of the gut.

scientific article published on 13 April 2012

Colchicine inhibits cationic dye uptake induced by ATP in P2X2 and P2X7 receptor-expressing cells: implications for its therapeutic action

scientific article

Contribution of sulfate-reducing bacteria to homeostasis disruption during intestinal inflammation

scientific article published on 07 November 2018

Crosstalk between purinergic receptors and lipid mediators in leishmaniasis

scientific article

Danger signals, inflammasomes, and the intricate intracellular lives of chlamydiae

scientific article

Decrease of serum adenine nucleotide hydrolysis in an irritant contact dermatitis mice model: potential P2X7R involvement

article

Differential modulation of ATP-induced P2X7-associated permeabilities to cations and anions of macrophages by infection with Leishmania amazonensis.

scientific article

Disruption of Purinergic Receptor P2X7 Signaling Increases Susceptibility to Cerebral Toxoplasmosis

scientific article published on 14 January 2019

Early expression of adenosine 5'-triphosphate-gated P2X7 receptors in the developing rat pancreas

scientific article published on 01 August 2007

Effect of extracellular ATP on the human leukaemic cell line K562 and its multidrug counterpart.

scientific article published on 6 July 2006

Expression of purinergic receptors and modulation of P2X7 function by the inflammatory cytokine IFNgamma in human epithelial cells.

scientific article published on 21 March 2009

Extracellular ATP induces cell death in CD4+/CD8+ double-positive thymocytes in mice infected with Trypanosoma cruzi.

scientific article published in December 2003

Extracellular ATP: a further modulator in neuroendocrine control of the thymus

scientific article published on 01 January 1999

Host-cell lipid rafts: a safe door for micro-organisms?

scientific article published on 06 April 2010

Hyperhomocysteinemia alters cytokine gene expression, cytochrome c oxidase activity and oxidative stress in striatum and cerebellum of rodents

scientific article published in 2021

Immunological Pathways Triggered by Porphyromonas gingivalis and Fusobacterium nucleatum: Therapeutic Possibilities?

scientific article published on 24 June 2019

Immunomodulatory effects of P2X7 receptor in intracellular parasite infections

scientific article published on 20 March 2019

Impairment of the splenic immune system in P2X(2)/P2X(3) knockout mice

scientific article

Implication of purinergic P2X7 receptor in M. tuberculosis infection and host interaction mechanisms: a mouse model study

scientific article published on 16 March 2013

Increased expression of NTPDases 2 and 3 in mesenteric endothelial cells during schistosomiasis favors leukocyte adhesion through P2Y1 receptors

scientific article

Infection with Leishmania amazonensis upregulates purinergic receptor expression and induces host-cell susceptibility to UTP-mediated apoptosis.

scientific article published on 11 July 2011

Inflammatory early events associated to the role of P2X7 receptor in acute murine toxoplasmosis

scientific article published on 30 December 2016

Inhibition of chlamydial infectious activity due to P2X7R-dependent phospholipase D activation.

scientific article published on September 2003

Intralesional uridine-5'-triphosphate (UTP) treatment induced resistance to Leishmania amazonensis infection by boosting Th1 immune responses and reactive oxygen species production

scientific article published on 21 April 2018

Is the inflammasome relevant for epithelial cell function?

scientific article

Leukotriene B4 modulates P2X7 receptor-mediated Leishmania amazonensis elimination in murine macrophages

scientific article published on 11 April 2014

Lipopolysaccharide-induced lung injury: role of P2X7 receptor.

scientific article

Macrophage P2X7 receptor function is reduced during schistosomiasis: putative role of TGF- β1.

scientific article

Modulation of P2X(7) purinergic receptor in macrophages by Leishmania amazonensis and its role in parasite elimination.

scientific article published on 09 May 2009

Modulation of P2X7 receptor expression in macrophages from mineral oil-injected mice

scientific article published on 4 January 2008

Modulation of intercellular communication in macrophages: possible interactions between GAP junctions and P2 receptors

scientific journal article

Modulation of mouse embryonic stem cell proliferation and neural differentiation by the P2X7 receptor

scientific article

Multiple P2X and P2Y receptor subtypes in mouse J774, spleen and peritoneal macrophages

scientific journal article

Non-canonical NLRP3 inflammasome activation and IL-1β signaling are necessary to L. amazonensis control mediated by P2X7 receptor and leukotriene B4

scientific article published on 24 June 2019

Oral infection of mice with Fusobacterium nucleatum results in macrophage recruitment to the dental pulp and bone resorption

scientific article published on 01 June 2018

Overexpression of ATP-activated P2X7 receptors in the intestinal mucosa is implicated in the pathogenesis of Crohn's disease

scientific article published on March 2014

P2X and P2Y purinergic receptors on human intestinal epithelial carcinoma cells: effects of extracellular nucleotides on apoptosis and cell proliferation.

scientific article published on 20 January 2005

P2X and P2Y purinoceptor expression in pancreas from streptozotocin-diabetic rats

scientific article published in June 2003

P2X7 Receptor Signaling Contributes to Sepsis-Associated Brain Dysfunction

scientific article published on 11 October 2016

P2X7 modulatory web in Trypanosoma cruzi infection

scientific article published on 8 July 2008

P2X7 receptor activation increases expression of caveolin-1 and formation of macrophage lipid rafts, thereby boosting CD39 activity

scientific article published on 06 March 2020

P2X7 receptor deletion attenuates oxidative stress and liver damage in sepsis

scientific article published on 22 October 2020

P2X7 receptor drives Th1 cell differentiation and controls the follicular helper T cell population to protect against Plasmodium chabaudi malaria.

scientific article

P2X7 receptor is required for neutrophil accumulation in a mouse model of irritant contact dermatitis.

scientific article published in March 2013

P2X7 receptor knockout prevents streptozotocin-induced type 1 diabetes in mice.

scientific article

P2X7 receptor modulates inflammatory and functional pulmonary changes induced by silica

scientific article

P2Y2 Receptor Induces L. amazonensis Infection Control in a Mechanism Dependent on Caspase-1 Activation and IL-1β Secretion

scientific article published on 01 October 2020

Pathological concentrations of homocysteine increases IL-1β production in macrophages in a P2X7, NF-ĸB, and erk-dependent manner

scientific article published on 12 August 2015

Periodate-oxidized ATP modulates macrophage functions during infection with Leishmania amazonensis

scientific article published on 7 May 2014

Pharmacological and molecular characterization of functional P2 receptors in rat embryonic cardiomyocytes.

scientific article

Pharmacological blockage and P2X7 deletion hinder aversive memories: reversion in an enriched environment

scientific article published on 18 September 2014

Porphyromonas gingivalis fimbriae dampen P2X7-dependent interleukin-1β secretion.

scientific article

Potential role of P2X7R in esophageal squamous cell carcinoma proliferation

scientific article

Presence of the P2X(7) purinergic receptor on immune cells that invade the rat endometrium during oestrus

scientific article

Prophylactic systemic P2X7 receptor blockade prevents experimental colitis

scientific article published on 30 October 2013

Pulmonary infection with hypervirulent Mycobacteria reveals a crucial role for the P2X7 receptor in aggressive forms of tuberculosis

scientific article

Purinergic Cooperation Between P2Y and P2X7 Receptors Promote Cutaneous Leishmaniasis Control: Involvement of Pannexin-1 and Leukotrienes

scientific article published on 09 July 2018

Purinergic receptor agonists modulate phagocytosis and clearance of apoptotic cells in macrophages.

scientific article

Purinergic signaling during Porphyromonas gingivalis infection

scientific article

Purinergic signaling in infection and autoimmune disease.

scientific article published on 27 October 2016

Pyrimidinergic Receptor Activation Controls Toxoplasma gondii Infection in Macrophages

scientific article (publication date: 2015)

Reversible inhibition of Chlamydia trachomatis infection in epithelial cells due to stimulation of P2X(4) receptors.

scientific article

Role of P2X7 Receptor in an Animal Model of Mania Induced by D-Amphetamine.

scientific article published on 11 December 2014

Silica-induced inflammasome activation in macrophages: role of ATP and P2X7 receptor.

scientific article published on 18 May 2015

Sulfate-reducing bacteria stimulate gut immune responses and contribute to inflammation in experimental colitis.

scientific article published on 11 September 2017

Sulphate-reducing bacteria from ulcerative colitis patients induce apoptosis of gastrointestinal epithelial cells

scientific article

The P2X(7) receptor and intracellular pathogens: a continuing struggle.

scientific article published on 12 February 2009

The P2X7 Receptor Contributes to the Development of the Exacerbated Inflammatory Response Associated with Sepsis.

scientific article published on 13 February 2015

The P2X7 Receptor Mediates Toxoplasma gondii Control in Macrophages through Canonical NLRP3 Inflammasome Activation and Reactive Oxygen Species Production

scientific article published on 12 October 2017

The giant artery: blood and blood vessels in a science museum

scientific article published on 31 December 2019

The purinergic receptor P2X7 role in control of Dengue virus-2 infection and cytokine/chemokine production in infected human monocytes.

scientific article

The role of P2X7 purinergic receptors in inflammatory and nociceptive changes accompanying cyclophosphamide-induced haemorrhagic cystitis in mice.

scientific article published on January 2012

The role of P2X7 receptor in infectious inflammatory diseases and the influence of ectonucleotidases.

scientific article published on July 2014

The role of purinergic P2X7 receptors in the inflammation and fibrosis of unilateral ureteral obstruction in mice

scientific journal article

The role of the P2X7 receptor in murine cutaneous leishmaniasis: aspects of inflammation and parasite control

scientific article

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