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List of works by Irwin Davidson

A Brn2-Zic1 axis specifies the neuronal fate of retinoic-acid-treated embryonic stem cells

scientific article published on 19 May 2015

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

scientific article

A TATA-less promoter containing binding sites for ubiquitous transcription factors mediates cell type-specific regulation of the gene for transcription enhancer factor-1 (TEF-1)

scientific article

A cell-specific factor represses stimulation of transcription in vitro by transcriptional enhancer factor 1.

scientific article published on August 1994

A functional interaction between ATF7 and TAF12 that is modulated by TAF4

scientific article

A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain

scientific article

Abnormal sperm in mice lacking the Taf7l gene

scientific journal article

All six GC-motifs of the SV40 early upstream element contribute to promoter activity in vivo and in vitro.

scientific article published on December 1985

BRCA1 is a new MITF target gene.

scientific article

BRN2 is a non-canonical melanoma tumor-suppressor

scientific article published on 17 June 2021

Brn-2 Represses Microphthalmia-Associated Transcription Factor Expression and Marks a Distinct Subpopulation of Microphthalmia-Associated Transcription Factor-Negative Melanoma Cells

scientific article published on 01 October 2008

Cdx2 determines the fate of postnatal intestinal endoderm

scientific journal article

Cell-specific nucleolar localization of TBP-related factor 2

scientific article

Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells

scientific article

Cell-type specific protein binding to the enhancer of simian virus 40 in nuclear extracts

scientific article

Changes in intranuclear chromatin architecture induce bipolar nuclear localization of histone variant H1T2 in male haploid spermatids

scientific journal article

Characterization of a HeLa cell factor which negatively regulates transcriptional activation in vitro by transcriptional enhancer factor-1 (TEF-1).

scientific article published on February 1995

Characterization of the transcription activation function and the DNA binding domain of transcriptional enhancer factor-1

scientific article

Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.

scientific article

Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB.

scientific article

Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID

scientific article

Cloning, expression, and transcriptional properties of the human enhancer factor TEF-1

scientific article

Comprehensive integrative profiling of upper tract urothelial carcinomas

scientific article published on 04 January 2021

Coordinate regulation of RARgamma2, TBP, and TAFII135 by targeted proteolysis during retinoic acid-induced differentiation of F9 embryonal carcinoma cells

scientific article

Crystal structure of a subcomplex of human transcription factor TFIID formed by TATA binding protein-associated factors hTAF4 (hTAF(II)135) and hTAF12 (hTAF(II)20)

scientific article

Different TBP-associated factors are required for mediating the stimulation of transcription in vitro by the acidic transactivator GAL-VP16 and the two nonacidic activation functions of the estrogen receptor.

scientific article published on January 1993

Differential expression of the TEF family of transcription factors in the murine placenta and during differentiation of primary human trophoblasts in vitro

scientific article published in July 1998

Distinct TFIID complexes mediate the effect of different transcriptional activators

scientific article

Distinct domains of hTAFII100 are required for functional interaction with transcription factor TFIIF beta (RAP30) and incorporation into the TFIID complex

scientific article

Distinct mutations in yeast TAF(II)25 differentially affect the composition of TFIID and SAGA complexes as well as global gene expression patterns.

scientific article

Erratum: Corrigendum: A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

scientific article published in Nature

Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma.

scientific article published on 24 January 2011

Essential role of the TFIID subunit TAF4 in murine embryogenesis and embryonic stem cell differentiation

scientific article published on 30 March 2016

Expanded polyglutamine stretches interact with TAFII130, interfering with CREB-dependent transcription

scientific article

Expression of an immediate early polypeptide and activation of a viral origin of DNA replication in cells containing a fragment of herpes simplex virus DNA.

scientific article published in February 1985

Front seat and back seat drivers of melanoma metastasis

scientific article published on 26 September 2011

Functional analysis of the TFIID-specific yeast TAF4 (yTAF(II)48) reveals an unexpected organization of its histone-fold domain

scientific article (publication date: 22 November 2002)

Functional and structural analysis of the subunits of human transcription factor TFIID.

scientific article

Functional interaction between the homeoprotein CDX1 and the transcriptional machinery containing the TATA-binding protein

scientific article published on 7 December 2006

Genomic structure and chromosomal mapping of the mouse transcription factor TEF-5 (Tead3) gene

scientific article published in June 1999

Global transcription regulators of eukaryotes

scientific article published on 01 March 1999

HCV-Induced Epigenetic Changes Associated With Liver Cancer Risk Persist After Sustained Virologic Response

scientific article published on 02 March 2019

HMGB4, a novel member of the HMGB family, is preferentially expressed in the mouse testis and localizes to the basal pole of elongating spermatids.

scientific article published on 5 November 2008

Histone folds mediate selective heterodimerization of yeast TAF(II)25 with TFIID components yTAF(II)47 and yTAF(II)65 and with SAGA component ySPT7.

scientific article published on March 2001

Human TAF(II)135 potentiates transcriptional activation by the AF-2s of the retinoic acid, vitamin D3, and thyroid hormone receptors in mammalian cells

scientific article

Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family

scientific article

Human TAF(II)28 interacts with the human T cell leukemia virus type I Tax transactivator and promotes its transcriptional activity

scientific article

Human TAF(II)55 interacts with the vitamin D(3) and thyroid hormone receptors and with derivatives of the retinoid X receptor that have altered transactivation properties

scientific article

Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors

scientific article

Human TAFII30 is present in a distinct TFIID complex and is required for transcriptional activation by the estrogen receptor

scientific article

Human TEF-5 is preferentially expressed in placenta and binds to multiple functional elements of the human chorionic somatomammotropin-B gene enhancer

scientific article

Hypomorphic Pathogenic Variants in TAF13 Are Associated with Autosomal-Recessive Intellectual Disability and Microcephaly

scientific article published on March 2017

Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression

scientific article

Improved Protocol for Chromatin Immunoprecipitation from Mouse Skeletal Muscle

scientific article published on 6 November 2017

In vitro binding of cell-specific and ubiquitous nuclear proteins to the octamer motif of the SV40 enhancer and related motifs present in other promoters and enhancers

scientific article published on October 1987

In vitro binding of several cell-specific and ubiquitous nuclear proteins to the GT-I motif of the SV40 enhancer

scientific article published on 01 October 1987

Interaction between T antigen and TEA domain of the factor TEF-1 derepresses simian virus 40 late promoter in vitro: identification of T-antigen domains important for transcription control

scientific article

Interaction of human papillomavirus 8 regulatory proteins E2, E6 and E7 with components of the TFIID complex

scientific article published on 01 January 1998

Interconversion between active and inactive TATA-binding protein transcription complexes in the mouse genome

scientific article published on 19 October 2011

Late arrest of spermiogenesis and germ cell apoptosis in mice lacking the TBP-like TLF/TRF2 gene

scientific article published in March 2001

Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis

scientific article

MITF and c-Jun antagonism interconnects melanoma dedifferentiation with pro-inflammatory cytokine responsiveness and myeloid cell recruitment

scientific article

MITF is a critical regulator of the carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) in malignant melanoma

scientific article published on 24 August 2015

MITF, the Janus transcription factor of melanoma.

scientific article published on February 2013

Macrophage production and activation are dependent on TRIM33.

scientific article published on 10 December 2016

Melanoma addiction to the long non-coding RNA SAMMSON.

scientific article published in March 2016

Multiple interactions between hTAFII55 and other TFIID subunits. Requirements for the formation of stable ternary complexes between hTAFII55 and the TATA-binding protein

scientific article

NF-Y Recruitment of TFIID, Multiple Interactions with Histone Fold TAFIIs

scientific article published in Journal of Biological Chemistry

Neuronal identity genes regulated by super-enhancers are preferentially down-regulated in the striatum of Huntington's disease mice

scientific article published on 17 March 2015

No evidence for generation of alternatively spliced isoforms from the mutated Trim24 allele lacking exon 4 in mouse liver

scientific article

Pericentric heterochromatin reprogramming by new histone variants during mouse spermiogenesis.

scientific article

Phosphorylation of BRN2 modulates its interaction with the Pax3 promoter to control melanocyte migration and proliferation

scientific article published on 30 January 2012

Phosphorylation of the retinoic acid receptor RARγ2 is crucial for the neuronal differentiation of mouse embryonic stem cells.

scientific article published on 25 February 2014

Polar nuclear localization of H1T2, a histone H1 variant, required for spermatid elongation and DNA condensation during spermiogenesis

scientific article

Preparation, isolation and characterization of stage-specific spermatogenic cells for cellular and molecular analysis

scientific article published on 01 December 2004

Proteolytic cleavage of ALF into alpha- and beta-subunits that form homologous and heterologous complexes with somatic TFIIA and TRF2 in male germ cells

scientific journal article

RNA polymerase II transcription in murine cells lacking the TATA binding protein

scientific journal article

Recent advances in understanding the structure and function of general transcription factor TFIID.

scientific article published on 24 March 2009

Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma

scientific article

Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor

scientific article published on October 2015

Retinoic acid induces Sertoli cell paracrine signals for spermatogonia differentiation but cell autonomously drives spermatocyte meiosis

scientific article

Retinoic acid induces TGFbeta-dependent autocrine fibroblast growth

scientific article published on 16 July 2007

Retinoic acid receptors recognize the mouse genome through binding elements with diverse spacing and topology.

scientific article

SIRT1 promotes proliferation and inhibits the senescence-like phenotype in human melanoma cells

scientific article

Selective elimination of long INterspersed element-1 expressing tumour cells by targeted expression of the HSV-TK suicide gene

scientific article

Sequence-specific transactivators counteract topoisomerase II-mediated inhibition of in vitro transcription by RNA polymerases I and II.

scientific article published on August 1993

Single cell transcriptomics reveal trans-differentiation of pancreatic beta cells following inactivation of the TFIID subunit Taf4

scientific article published on 12 August 2021

Single-cell gene expression signatures reveal melanoma cell heterogeneity.

scientific article published on 18 August 2014

Structural basis of natural promoter recognition by the retinoid X nuclear receptor

scientific article

Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation

scientific article published on 26 July 2013

T-cell-intrinsic Tif1α/Trim24 regulates IL-1R expression on TH2 cells and TH2 cell-mediated airway allergy.

scientific article published on 19 January 2016

TAF4 inactivation in embryonic fibroblasts activates TGF beta signalling and autocrine growth.

scientific article

TAF4 inactivation reveals the 3 dimensional growth promoting activities of collagen 6A3.

scientific article published on 3 February 2014

TAF4, a subunit of transcription factor II D, directs promoter occupancy of nuclear receptor HNF4A during post-natal hepatocyte differentiation.

scientific article

TAF4/4b x TAF12 displays a unique mode of DNA binding and is required for core promoter function of a subset of genes

scientific article

TAF4b and Jun/activating protein-1 collaborate to regulate the expression of integrin alpha6 and cancer cell migration properties

scientific article published on 30 March 2010

TAF7 (TAFII55) plays a role in the transcription activation by c-Jun

scientific article

TATA box-binding protein-associated factor 12 is important for RAS-induced transformation properties of colorectal cancer cells.

scientific article

TEAD transcription factors are required for normal primary myoblast differentiation in vitro and muscle regeneration in vivo

scientific article

TIPT, a male germ cell-specific partner of TRF2, is chromatin-associated and interacts with HP1

scientific journal article

TONDU (TDU), a novel human protein related to the product of vestigial (vg) gene of Drosophila melanogaster interacts with vertebrate TEF factors and substitutes for Vg function in wing formation

scientific article

TRIM33 switches off Ifnb1 gene transcription during the late phase of macrophage activation

scientific article

The HeLa cell protein TEF-1 binds specifically and cooperatively to two SV40 enhancer motifs of unrelated sequence

scientific article published in September 1988

The Krüppel-like core promoter binding protein gene is primarily expressed in placenta during mouse development.

scientific article published in December 1999

The SV40 TC-II(kappa B) enhanson binds ubiquitous and cell type specifically inducible nuclear proteins from lymphoid and non-lymphoid cell lines

scientific article published on December 1989

The TATA-binding protein and its associated factors are differentially expressed in adult mouse tissues

scientific article published on 01 May 1999

The TFIID components human TAF(II)140 and Drosophila BIP2 (TAF(II)155) are novel metazoan homologues of yeast TAF(II)47 containing a histone fold and a PHD finger

scientific article

The TFIID subunit TAF4 regulates keratinocyte proliferation and has cell-autonomous and non-cell-autonomous tumour suppressor activity in mouse epidermis

scientific article

The TIF1α-related TRIM cofactors couple chromatin modifications to transcriptional regulation, signaling and tumor suppression.

scientific article published on September 2011

The genetics of TBP and TBP-related factors

scientific article (publication date: July 2003)

The histone deacetylase SIRT1 controls male fertility in mice through regulation of hypothalamic-pituitary gonadotropin signaling

scientific article

The histone fold is a key structural motif of transcription factor TFIID.

scientific article

The human TFIID components TAF(II)135 and TAF(II)20 and the yeast SAGA components ADA1 and TAF(II)68 heterodimerize to form histone-like pairs

scientific article

The human transcription factor IID subunit human TATA-binding protein-associated factor 28 interacts in a ligand-reversible manner with the vitamin D(3) and thyroid hormone receptors

scientific article

The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation

scientific article (publication date: May 2003)

The transactivation domain of adenovirus E1A interacts with the C terminus of human TAF(II)135.

scientific article published in October 1997

Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

scientific article

Transcription cofactors TRIM24, TRIM28, and TRIM33 associate to form regulatory complexes that suppress murine hepatocellular carcinoma

scientific article

Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells

scientific article published on 24 March 2015

Transcription factor TEAD4 regulates expression of myogenin and the unfolded protein response genes during C2C12 cell differentiation

scientific article (publication date: February 2012)

Transcriptional activation by simian virus 40 large T antigen: interactions with multiple components of the transcription complex

scientific article

Transcriptional enhancer factor (TEF)-1 and its cell-specific co-activator activate human papillomavirus-16 E6 and E7 oncogene transcription in keratinocytes and cervical carcinoma cells

scientific article

Trim24-repressed VL30 retrotransposons regulate gene expression by producing noncoding RNA.

scientific article published on 3 February 2013

Unique aspects of transcription regulation in male germ cells

scientific article

[TBP, a universal transcription factor?]

scientific article published on 01 May 2004

seqMINER: an integrated ChIP-seq data interpretation platform

scientific article

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