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List of works by Allan Lawrie

A report on the use of animal models and phenotyping methods in pulmonary hypertension research

scientific article published on March 2014

A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension

scientific article published on 15 November 2019

A toolbox for the longitudinal assessment of healthspan in aging mice

scientific article published on 08 January 2020

Apolipoprotein D and platelet-derived growth factor-BB synergism mediates vascular smooth muscle cell migration

scientific article published on 10 June 2004

Apolipoprotein D inhibits platelet-derived growth factor-BB-induced vascular smooth muscle cell proliferated by preventing translocation of phosphorylated extracellular signal regulated kinase 1/2 to the nucleus

scientific article

Blood flow suppresses vascular Notch signalling via dll4 and is required for angiogenesis in response to hypoxic signalling.

scientific article published on 30 July 2013

Bosutinib therapy resulting in severe deterioration of pre-existing pulmonary arterial hypertension.

scientific article

Deficiency of tumour necrosis factor-related apoptosis-inducing ligand exacerbates lung injury and fibrosis.

scientific article

Deprivation and prognosis in patients with Pulmonary Arterial Hypertension: missing the effect of deprivation on a rare disease?

scientific article published on 16 April 2020

Differential IL-1 signaling induced by BMPR2 deficiency drives pulmonary vascular remodeling

scientific article published in January 2017

Elevated plasma CXCL12α is associated with a poorer prognosis in pulmonary arterial hypertension

scientific article

Expression Quantitative Trait Locus Mapping in Pulmonary Arterial Hypertension

scientific article published on 22 October 2020

From bones to blood pressure, developing novel biologic approaches targeting the osteoprotegein pathway for pulmonary vascular disease

scientific article

Heart rate reduction with ivabradine promotes shear stress-dependent anti-inflammatory mechanisms in arteries

scientific article published on 14 April 2016

Identification of rare sequence variation underlying heritable pulmonary arterial hypertension.

scientific article published on 12 April 2018

Identifying early pulmonary arterial hypertension biomarkers in systemic sclerosis: Machine learning on proteomics from the DETECT cohort

scientific article published on 17 December 2020

Influence of pre-analytical and analytical factors on osteoprotegerin measurements

scientific article published on 17 May 2014

Inhibition of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) reverses experimental pulmonary hypertension

scientific article

Interdependent serotonin transporter and receptor pathways regulate S100A4/Mts1, a gene associated with pulmonary vascular disease

scientific article published on 7 July 2005

Low-Dose FK506 (Tacrolimus) in End-Stage Pulmonary Arterial Hypertension

scientific article published on July 2015

MicroRNA in pulmonary vascular disease.

scientific article published on January 2014

MicroRNA-140-5p and SMURF1 regulate pulmonary arterial hypertension

scientific article

Mts1/S100A4 stimulates human pulmonary artery smooth muscle cell migration through multiple signaling pathways

scientific article published on 01 December 2005

No evidence for cardiac dysfunction in Kif6 mutant mice

scientific article

Osteoprotegerin in Cardiometabolic Disorders

scientific article published on 11 May 2015

Plasma Metabolomics Implicates Modified Transfer RNAs and Altered Bioenergetics in the Outcomes of Pulmonary Arterial Hypertension.

scientific article

Pulmonary Artery Denervation Attenuates Pulmonary Arterial Remodeling in Dogs With Pulmonary Arterial Hypertension Induced by Dehydrogenized Monocrotaline.

scientific article published in December 2015

Pulmonary artery denervation reduces pulmonary artery pressure and induces histological changes in an acute porcine model of pulmonary hypertension

scientific article

Pulmonary hypertension in COPD: results from the ASPIRE registry.

scientific article

Reduced microRNA-150 is associated with poor survival in pulmonary arterial hypertension.

scientific article published on 6 December 2012

S100A4 and bone morphogenetic protein-2 codependently induce vascular smooth muscle cell migration via phospho-extracellular signal-regulated kinase and chloride intracellular channel 4

scientific article

Selective improvement of pulmonary arterial hypertension with a dual ETA/ETB receptors antagonist in the apolipoprotein E-/- model of PAH and atherosclerosis.

scientific article published in January 2017

Serum osteoprotegerin is increased and predicts survival in idiopathic pulmonary arterial hypertension

scientific article published in January 2012

Targeting Vascular Remodeling to Treat Pulmonary Arterial Hypertension

scientific article published on 15 December 2016

The Hepcidin/Ferroportin axis modulates proliferation of pulmonary artery smooth muscle cells

scientific article published in Scientific Reports

The role of chemokines and chemokine receptors in pulmonary arterial hypertension

scientific article published on 10 August 2019

The role of the osteoprotegerin/tumor necrosis factor related apoptosis-inducing ligand axis in the pathogenesis of pulmonary arterial hypertension

scientific article

Ultrasound gene therapy: on the road from concept to reality.

scientific article published in May 2001

Ultrasound-enhanced transgene expression in vascular cells is not dependent upon cavitation-induced free radicals.

scientific article published in October 2003

Utilising artificial intelligence to determine patients at risk of a rare disease: idiopathic pulmonary arterial hypertension

scientific article published on 01 October 2019

VP22-mediated intercellular transport correlates with enhanced biological activity of MybEngrailed but not (HSV-I) thymidine kinase fusion proteins in primary vascular cells following non-viral transfection

scientific article published in March 2005

miRNA-140-5p: new avenue for pulmonary arterial hypertension drug development?

scientific article published on 7 September 2016

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