List of works - Marçal Vilar

A two-step inactivation mechanism of Myt1 ensures CDK1/cyclin B activation and meiosis I entry

scientific article published in April 2010

Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers

scientific article

Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses

scientific article

Aβ increases neural stem cell activity in senescence-accelerated SAMP8 mice

scientific article published on 22 June 2013

Bex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle

scientific article

Brain expressed and X-linked (Bex) proteins are intrinsically disordered proteins (IDPs) and form new signaling hubs

scientific article published on 22 January 2015

Characterization of Novel Missense Variants of SERPINA1 Gene Causing Alpha-1 Antitrypsin Deficiency

scientific article published on 12 December 2017

Forkhead transcription factor FKH-8 cooperates with RFX in the direct regulation of sensory cilia in Caenorhabditis elegans

scientific article published on 14 July 2023

Functional and structural deficiencies of Gemin5 variants associated with neurological disorders

scientific article published on 07 April 2022

Heterodimerization of p45-p75 modulates p75 signaling: structural basis and mechanism of action.

scientific article

In vivo demonstration that alpha-synuclein oligomers are toxic

scientific article

Insertion and topology of a plant viral movement protein in the endoplasmic reticulum membrane

scientific article published on 25 April 2002

Interaction between the transmembrane domains of neurotrophin receptors p75 and TrkA mediates their reciprocal activation

scientific article published on 01 July 2021

Ionic self-complementarity induces amyloid-like fibril formation in an isolated domain of a plant copper metallochaperone protein

scientific article

Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor

scientific article published on 25 August 2009

Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF.

scientific article

Membrane insertion and topology of the p7B movement protein of Melon Necrotic Spot Virus (MNSV).

scientific article

Membrane insertion and topology of the translocating chain-associating membrane protein (TRAM).

scientific article published on 13 January 2011

Mutations in TrkA Causing Congenital Insensitivity to Pain with Anhidrosis (CIPA) Induce Misfolding, Aggregation, and Mutation-dependent Neurodegeneration by Dysfunction of the Autophagic Flux

scientific article published on 22 August 2016

NMR Dynamics of Transmembrane and Intracellular Domains of p75NTR in Lipid-Protein Nanodiscs.

scientific article published on August 2015

P45 forms a complex with FADD and promotes neuronal cell survival following spinal cord injury

scientific article

Protein-tyrosine phosphatase SHP2 contributes to GDNF neurotrophic activity through direct binding to phospho-Tyr687 in the RET receptor tyrosine kinase.

scientific article published on 3 August 2010

Regulation of Neurogenesis by Neurotrophins during Adulthood: Expected and Unexpected Roles

scientific article

Structural Basis of p75 Transmembrane Domain Dimerization.

scientific article published on 7 April 2016

Structural Characterization of the p75 Neurotrophin Receptor: A Stranger in the TNFR Superfamily

scientific article published on 29 November 2016

Structural Studies of Amyloids by Quenched Hydrogen–Deuterium Exchange by NMR

scientific article published on 01 January 2012

Structural basis of the transmembrane domain dimerization and rotation in the activation mechanism of the TRKA receptor by nerve growth factor

scientific article published on 04 December 2019

Structural properties of carnation mottle virus p7 movement protein and its RNA-binding domain

scientific article

Synthetic pulmonary surfactant preparations: new developments and future trends.

scientific article published on January 2008

The coat protein of prunus necrotic ringspot virus specifically binds to and regulates the conformation of its genomic RNA.

scientific article published in August 2003

The fold of alpha-synuclein fibrils

scholarly article

Transient structural ordering of the RNA-binding domain of carnation mottle virus p7 movement protein modulates nucleic acid binding

scientific article

List of works by Marçal Vilar

A two-step inactivation mechanism of Myt1 ensures CDK1/cyclin B activation and meiosis I entry

Activation of the p75 neurotrophin receptor through conformational rearrangement of disulphide-linked receptor dimers

Altered marginal zone and innate-like B cells in aged senescence-accelerated SAMP8 mice with defective IgG1 responses

Aβ increases neural stem cell activity in senescence-accelerated SAMP8 mice

Bex1, a novel interactor of the p75 neurotrophin receptor, links neurotrophin signaling to the cell cycle

Brain expressed and X-linked (Bex) proteins are intrinsically disordered proteins (IDPs) and form new signaling hubs

Characterization of Novel Missense Variants of SERPINA1 Gene Causing Alpha-1 Antitrypsin Deficiency

Forkhead transcription factor FKH-8 cooperates with RFX in the direct regulation of sensory cilia in Caenorhabditis elegans

Functional and structural deficiencies of Gemin5 variants associated with neurological disorders

Heterodimerization of p45-p75 modulates p75 signaling: structural basis and mechanism of action.

In vivo demonstration that alpha-synuclein oligomers are toxic

Insertion and topology of a plant viral movement protein in the endoplasmic reticulum membrane

Interaction between the transmembrane domains of neurotrophin receptors p75 and TrkA mediates their reciprocal activation

Ionic self-complementarity induces amyloid-like fibril formation in an isolated domain of a plant copper metallochaperone protein

Ligand-independent signaling by disulfide-crosslinked dimers of the p75 neurotrophin receptor

Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF.

Membrane insertion and topology of the p7B movement protein of Melon Necrotic Spot Virus (MNSV).

Membrane insertion and topology of the translocating chain-associating membrane protein (TRAM).

Mutations in TrkA Causing Congenital Insensitivity to Pain with Anhidrosis (CIPA) Induce Misfolding, Aggregation, and Mutation-dependent Neurodegeneration by Dysfunction of the Autophagic Flux

NMR Dynamics of Transmembrane and Intracellular Domains of p75NTR in Lipid-Protein Nanodiscs.

P45 forms a complex with FADD and promotes neuronal cell survival following spinal cord injury

Protein-tyrosine phosphatase SHP2 contributes to GDNF neurotrophic activity through direct binding to phospho-Tyr687 in the RET receptor tyrosine kinase.

Regulation of Neurogenesis by Neurotrophins during Adulthood: Expected and Unexpected Roles

Structural Basis of p75 Transmembrane Domain Dimerization.

Structural Characterization of the p75 Neurotrophin Receptor: A Stranger in the TNFR Superfamily

Structural Studies of Amyloids by Quenched Hydrogen–Deuterium Exchange by NMR

Structural basis of the transmembrane domain dimerization and rotation in the activation mechanism of the TRKA receptor by nerve growth factor

Structural properties of carnation mottle virus p7 movement protein and its RNA-binding domain

Synthetic pulmonary surfactant preparations: new developments and future trends.

The coat protein of prunus necrotic ringspot virus specifically binds to and regulates the conformation of its genomic RNA.

The fold of alpha-synuclein fibrils

Transient structural ordering of the RNA-binding domain of carnation mottle virus p7 movement protein modulates nucleic acid binding