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List of works by Alex Harwig

Analysis of AgoshRNA maturation and loading into Ago2. ⬇️

scientific article published on 15 August 2017

Characterization of microRNAs derived from the HIV-1 TAR RNA hairpin.

scientific article published on 19 September 2013

Construction of Nef-positive doxycycline-dependent HIV-1 variants using bicistronic expression elements.

scientific article

Construction of a doxycycline-dependent simian immunodeficiency virus reveals a nontranscriptional function of tat in viral replication.

scientific article

Deep Sequence Analysis of AgoshRNA Processing Reveals 3' A Addition and Trimming

scientific article published on 14 July 2015

Deep sequencing of small TAR-derived RNAs in HIV-1 producing cells.

scientific article published on 3 October 2011

Destabilization of the TAR hairpin affects the structure and function of the HIV-1 leader RNA.

scientific article published on 27 June 2008

Destabilization of the TAR hairpin leads to extension of the polyA hairpin and inhibition of HIV-1 polyadenylation.

scientific article published on 11 February 2009

HIV-1 RNAs: sense and antisense, large mRNAs and small siRNAs and miRNAs.

scientific article published on March 2015

HIV-1 splicing is modulated by RNA structure.

scientific article published on 3 October 2011

HIV-1 transcriptional silencing caused by TRIM22 inhibition of Sp1 binding to the viral promoter

scientific article published on 18 December 2015

Mechanistic insights on the Dicer-independent AGO2-mediated processing of AgoshRNAs.

scientific article

Microprocessor, Setx, Xrn2, and Rrp6 co-operate to induce premature termination of transcription by RNAPII.

scientific article published on September 2012

Opening of the TAR hairpin in the HIV-1 genome causes aberrant RNA dimerization and packaging ⬇️

scientific article published on July 24, 2012

Probing the shRNA characteristics that hinder Dicer recognition and consequently allow Ago-mediated processing and AgoshRNA activity

scientific article published on 17 July 2014

RNA Polymerase Clamp Movement Aids Dissociation from DNA but Is Not Required for RNA Release at Intrinsic Terminators

scientific article published on 08 January 2019

Retroviral microRNAs

scientific article published on 23 April 2014

The Battle of RNA Synthesis: Virus versus Host

scientific article published on 21 October 2017

The HIV-1 Tat Protein Has a Versatile Role in Activating Viral Transcription ⬇️

scientific article published on July 13, 2011

The TAR hairpin of human immunodeficiency virus type 1 can be deleted when not required for Tat-mediated activation of transcription

scientific article published on 9 May 2007

The influence of the 5΄-terminal nucleotide on AgoshRNA activity and biogenesis: importance of the polymerase III transcription initiation site

scientific article

The viral Tat protein has no essential function in HIV-1 replication other than to activate transcription

article

Toward optimization of AgoshRNA molecules that use a non-canonical RNAi pathway: variations in the top and bottom base pairs

scientific article

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