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List of works by Luis A. Pardo

A CAG repeat polymorphism of KCNN3 predicts SK3 channel function and cognitive performance in schizophrenia

scientific article

A new mechanism of voltage-dependent gating exposed by KV10.1 channels interrupted between voltage sensor and pore

scientific article published on 30 March 2017

APETx4, a Novel Sea Anemone Toxin and a Modulator of the Cancer-Relevant Potassium Channel KV10.1.

scientific article published on 13 September 2017

ATP and noradrenaline activate CREB in astrocytes via noncanonical Ca(2+) and cyclic AMP independent pathways

scientific article

Activation of adenylate cyclase in cdc25 mutants of Saccharomyces cerevisiae

scientific article published on 01 March 1993

Altered ligand dissociation rates in thyrotropin-releasing hormone receptors mutated in glutamine 105 of transmembrane helix III.

scientific article published in March 1997

Alternating pH landscapes shape epithelial cancer initiation and progression: Focus on pancreatic cancer.

scientific article

Alternatively Spliced Isoforms of KV10.1 Potassium Channels Modulate Channel Properties and Can Activate Cyclin-dependent Kinase in Xenopus Oocytes

scientific article

Approaches targeting K(V)10.1 open a novel window for cancer diagnosis and therapy

scientific article published on January 2012

Behavioural and functional characterization of Kv10.1 (Eag1) knockout mice

scientific article

CD133 Expression Is Not Synonymous to Immunoreactivity for AC133 and Fluctuates throughout the Cell Cycle in Glioma Stem-Like Cells

scientific article published on 18 June 2015

Caffeine enhancement of electrical activity through direct blockade of inward rectifying K+ currents in GH3 rat anterior pituitary cells

scientific article

Characterization of Eag1 channel lateral mobility in rat hippocampal cultures by single-particle-tracking with quantum dots

scientific journal article

Concept of a selective tumour therapy and its evaluation by near-infrared fluorescence imaging and flat-panel volume computed tomography in mice.

scientific article published on 13 March 2009

Cortactin controls surface expression of the voltage-gated potassium channel K(V)10.1.

scientific article published on 9 November 2012

Cyclic expression of the voltage-gated potassium channel KV10.1 promotes disassembly of the primary cilium

scientific article published on 20 April 2016

Cytoskeletal interactions determine the electrophysiological properties of human EAG potassium channels

scientific article published in December 2000

Demonstration of an inwardly rectifying K+ current component modulated by thyrotropin-releasing hormone and caffeine in GH3 rat anterior pituitary cells.

scientific article

Different relevance of inactivation and F468 residue in the mechanisms of hEag1 channel blockage by astemizole, imipramine and dofetilide

scientific article published on 28 August 2006

Eag 1, Eag 2 and Kcnn3 gene brain expression of isolated reared rats

scientific article published on November 2010

Eag1 as a cancer target

scientific article published on 01 July 2008

Eag1 potassium channels as markers of cervical dysplasia.

scientific article

Eag1, Eag2, and SK3 potassium channel expression in the rat hippocampus after global transient brain ischemia

scientific article published on 18 October 2011

Eag1: an emerging oncological target.

scientific article published on March 2008

Ether a go-go potassium channels as human cervical cancer markers

scientific article

Ether à go-go potassium channel expression in soft tissue sarcoma patients

scientific article

Ether-à-go-go 1 (Eag1) potassium channel expression in dopaminergic neurons of basal ganglia is modulated by 6-hydroxydopamine lesion.

scientific article

Frequent aberrant expression of the human ether à go-go (hEAG1) potassium channel in head and neck cancer: pathobiological mechanisms and clinical implications.

scientific article

Functional KV10.1 Channels Localize to the Inner Nuclear Membrane ⬇️

scientific article published on May 3, 2011

Glucose activation of adenylate cyclase in Saccharomyces cerevisiae mutants lacking glucose-phosphorylating enzymes

scientific article published on 01 July 1993

Glycosylation of Eag1 (Kv10.1) potassium channels: intracellular trafficking and functional consequences

scientific article published on 17 June 2005

Guiding TRAIL to cancer cells through Kv10.1 potassium channel overcomes resistance to doxorubicin.

scientific article published on 27 June 2016

Hippocampal ether-à-go-go1 potassium channels blockade: effects in the startle reflex and prepulse inhibition

scientific journal article

Human glioma-initiating cells show a distinct immature phenotype resembling but not identical to NG2 glia

scientific article published on April 2013

In vitro activation of the Saccharomyces cerevisiae Ras/adenylate cyclase system by glucose and some of its analogues

scientific article published on 01 September 1991

In vivo imaging of tumour xenografts with an antibody targeting the potassium channel Kv10.1.

scientific article published on 21 July 2016

Inhibition of Kv10.1 Channels Sensitizes Mitochondria of Cancer Cells to Antimetabolic Agents

scientific article published on 09 April 2020

Ion channels in health and disease. 83rd Boehringer Ingelheim Fonds International Titisee Conference

scientific article published on July 2001

Ion channels, transporters and cancer ("INCA2015"): an international meeting in honor of Prof. Dr. Walter Stühmer

scientific article published on 20 July 2016

Ion channels: functional expression and therapeutic potential in cancer. Colloquium on Ion Channels and Cancer

scientific article published on 02 May 2008

K(+) channels as therapeutic targets in oncology.

scientific article published on May 2010

KV 10.1 opposes activity-dependent increase in Ca2+ influx into the presynaptic terminal of the parallel fibre-Purkinje cell synapse.

scientific article

KV10.1 K(+)-channel plasma membrane discrete domain partitioning and its functional correlation in neurons.

scientific article published on 22 November 2013

Kv10.1 K(+) channel: from physiology to cancer.

scientific article

Kv10.1 Regulates Microtubule Dynamics during Mitosis

scientific article published on 25 August 2020

Molecular basis for different pore properties of potassium channels from the rat brain Kv1 gene family

scientific article published in November 1997

Monoclonal Antibody Blockade of the Human Eag1 Potassium Channel Function Exerts Antitumor Activity

scientific article published on 01 August 2007

New Structures and Gating of Voltage-Dependent Potassium (Kv) Channels and Their Relatives: A Multi-Domain and Dynamic Question ⬇️

scientific article published on 10 January 2019

Nucleofection induces non-specific changes in the metabolic activity of transfected cells.

scientific article published on 5 June 2011

Oncogenic potential of EAG K(+) channels

scientific article

Overexpression of Eag1 potassium channels in clinical tumours.

scientific article

PIST (GOPC) modulates the oncogenic voltage-gated potassium channel KV10.1.

scientific article published on 14 August 2013

Pattern of axonal injury in murine myelin oligodendrocyte glycoprotein induced experimental autoimmune encephalomyelitis: Implications for multiple sclerosis

scientific article published on 26 January 2008

Periodic expression of Kv10.1 driven by pRb/E2F1 contributes to G2/M progression of cancer and non-transformed cells

scientific article published on March 2016

Physical and functional interaction of KV10.1 with Rabaptin-5 impacts ion channel trafficking

scientific article

Potassium channels in cell cycle and cell proliferation.

scientific article published on 03 February 2014

Rapid internalization of the oncogenic K+ channel K(V)10.1

scientific article

Role of voltage-gated potassium channels in cancer.

scientific article

SK3 Channel Overexpression in Mice Causes Hippocampal Shrinkage Associated with Cognitive Impairments.

scientific article

TRPM8 ion channels differentially modulate proliferation and cell cycle distribution of normal and cancer prostate cells

scientific article

The antitumor efficacy of monomeric disintegrin obtustatin in S-180 sarcoma mouse model

scientific article published on 25 January 2019

The electric fence to cell-cycle progression: Do local changes in membrane potential facilitate disassembly of the primary cilium?: Timely and localized expression of a potassium channel may set the conditions that allow retraction of the primary ci

scientific article

The potassium channel Ether à go-go is a novel prognostic factor with functional relevance in acute myeloid leukemia

scientific article

The roles of K(+) channels in cancer

scientific article published on 12 December 2013

The voltage dependence of hEag currents is not determined solely by membrane-spanning domains

scientific article published in April 2008

Tumor cell-selective apoptosis induction through targeting of K(V)10.1 via bifunctional TRAIL antibody.

scientific article published on 07 September 2011

Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains.

scientific article

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