List of works - Morten Grøtli

2,6,8-Trisubstituted 3-hydroxychromone derivatives as fluorophores for live-cell imaging.

scientific article published in September 2009

7-(Benzofuran-2-yl)-7-deazadeoxyguanosine as a fluorescence turn-ON probe for single-strand DNA binding protein

scientific article published on 11 February 2016

8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction

scientific article

A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos

scientific article

A Fluorescent Kinase Inhibitor that Exhibits Diagnostic Changes in Emission upon Binding

scientific article published on 05 September 2019

A Single-Cell Study of a Highly Effective Hog1 Inhibitor for in Situ Yeast Cell Manipulation

article published in 2014

An acido- and photochromic molecular device that mimics triode action

scientific article published on 7 March 2016

Application of a peptide-based assay to characterize inhibitors targeting protein kinases from yeast

scientific article

Arsenic Directly Binds to and Activates the Yeast AP-1-Like Transcription Factor Yap8.

scientific article published on 28 December 2015

Carbon- and oxygen-centered radicals are equally important haptens of allylic hydroperoxides in allergic contact dermatitis

scientific article published on 3 July 2008

Characterization of interactions and pharmacophore development for DFG-out inhibitors to RET tyrosine kinase

scientific article published on 6 June 2015

Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA. ⬇️

scientific article published on 29 January 2011

Chroman-4-one and chromone based somatostatin β-turn mimetics.

scientific article

Chromo-pharmacophores: photochromic diarylmaleimide inhibitors for sirtuins

Defects in the calcium-binding region drastically affect the cadherin-like domains of RET tyrosine kinase.

scientific article published in March 2016

Design, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53 Interaction

scientific article

Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase Inhibitors

scientific article published on 6 May 2015

Design, synthesis and characterization of a highly effective inhibitor for analog-sensitive (as) kinases

scientific article

Design, synthesis, and biological evaluation of chromone-based p38 MAP kinase inhibitors

scientific article published on 26 September 2011

Design, synthesis, and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signaling in yeast

scientific article

Determination of primary sequence specificity of Arabidopsis MAPKs MPK3 and MPK6 leads to identification of new substrates.

scientific article

Development of bright fluorescent quadracyclic adenine analogues: TDDFT-calculation supported rational design

scientific article published on 31 July 2015

Diffusion of reagents in macrobeads

scientific article

Discovering New Classes of Brugia malayi Asparaginyl-tRNA Synthetase Inhibitors and Relating Specificity to Conformational Change

scientific article published on 01 March 2006

Efficient synthesis of 2,5-diketopiperazines using microwave assisted heating

article published in 2006

Enhanced microwave-assisted method for on-bead disulfide bond formation: Synthesis of α-conotoxin MII

scientific article published in 2009

Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic β-hairpins

scientific article published on 12 October 2016

Fluorescent nucleobase analogues for base-base FRET in nucleic acids: synthesis, photophysics and applications.

scientific article published on 10 January 2018

Improving the economics of NASH/NAFLD treatment through the use of systems biology

scientific article

Inhibitors and promoters of tubulin polymerization: synthesis and biological evaluation of chalcones and related dienones as potential anticancer agents

scientific article published on 10 March 2011

Interbase FRET in RNA: from A to Z

scientific article published on 01 November 2019

KHMDS enhanced SmI(2)-mediated reformatsky type alpha-cyanation

scientific article published on 01 May 2010

Lighting Up DNA with the Environment-Sensitive Bright Adenine Analogue qAN4

scientific article published on 01 February 2020

Method for activation and recycling of trityl resins

scientific article published on 06 August 2012

Microwave-assisted solid-phase synthesis of 2,5-diketopiperazines: solvent and resin dependence

scientific article

NMR-based substrate analog docking to Escherichia coli peptidyl-tRNA hydrolase

scientific article

Network analyses identify liver-specific targets for treating liver diseases

scientific article published on 21 August 2017

Palladium on carbon encapsulated in POEPOP(1500): a resin-supported catalyst for hydrogenation reactions

scientific article published on 01 January 2002

Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogue

scientific article published on 01 March 2018

Peroxiredoxin promotes longevity and H2O2-resistance in yeast through redox-modulation of protein kinase A

scientific article published on 14 July 2020

Positional scanning peptide libraries for kinase substrate specificity determinations: straightforward and reproducible synthesis using pentafluorophenyl esters

scientific article

Preparation of 3-substituted-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amines as RET kinase inhibitors

scientific article

Pulse-shaped two-photon excitation of a fluorescent base analogue approaches single-molecule sensitivity

scientific article published on 01 November 2018

Role of the subunit composition of central nicotinic acetylcholine receptors for the stimulatory and dopamine-enhancing effects of ethanol

scientific article published on 23 June 2006

SPOCC-194, a new high functional group density PEG-based resin for solid-phase organic synthesis

scientific article published in September 2002

Second-generation fluorescent quadracyclic adenine analogues: environment-responsive probes with enhanced brightness

scientific article published on 29 January 2015

Selective inhibition of RET mediated cell proliferation in vitro by the kinase inhibitor SPP86. ⬇️

scientific article

Shining New Light on the Spiropyran Photoswitch: A Photocage Decides between cis- trans or Spiro-Merocyanine Isomerization

scientific article published on 18 October 2018

Short cut to 1,2,3-triazole-based p38 MAP kinase inhibitorsvia [3+2]-cycloaddition chemistry

Solid-Phase Peptide Synthesis in Water Using Microwave-Assisted Heating

scientific article published in 2009

Structural Insights into the Polyphyletic Origins of Glycyl tRNA Synthetases

scientific article published on 23 May 2016

Structural influence on radical formation and sensitizing capacity of alkylic limonene hydroperoxide analogues in allergic contact dermatitis

scientific article published in March 2010

Synthesis and Photophysical Characterisation of Fluorescent 8-(1H-1,2,3-Triazol-4-yl)adenosine Derivatives

Synthesis and Photophysical Characterization of Azoheteroarenes

scientific article published on 06 August 2018

Synthesis and photophysical characterisation of new fluorescent triazole adenine analogues

scientific article

Synthesis of 2'-([1,2,3]triazol-1-yl)-2'-deoxyadenosines

scientific article published in May 2008

Synthesis of 2,3,6,8-tetrasubstituted chromone scaffolds

scientific article published on 01 September 2006

Synthesis of 2-alkyl-substituted chromone derivatives using microwave irradiation

scientific article

Synthesis of 3-(1,2,3-triazol-1-yl)- and 3-(1,2,3-triazol-4-yl)-substituted pyrazolo[3,4-d]pyrimidin-4-amines via click chemistry: potential inhibitors of the Plasmodium falciparum PfPK7 protein kinase

scientific article published on 2 July 2009

Synthesis of chiral 1,4-disubstituted-1,2,3-triazole derivatives from amino acids

scientific article published on 9 December 2009

Synthesis of functionalized, unsymmetrical 1,3,4,6-tetrasubstituted 2,5-diketopiperazines

scientific article published on 01 January 2007

Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine analogue

scientific article published in Scientific Reports

The biotin repressor: modulation of allostery by corepressor analogs

scientific article published in April 2004

The unique characteristics of HOG pathway MAPKs in the extremely halotolerant Hortaea werneckii

scientific article published on 30 March 2015

Toward Complete Sequence Flexibility of Nucleic Acid Base Analogue FRET.

scientific article published on 14 June 2017

Towards the development of chromone-based MEK1/2 modulators

scientific article

Validation of regulated protein phosphorylation events in yeast by quantitative mass spectrometry analysis of purified proteins

scientific article published on 19 September 2012

List of works by Morten Grøtli

2,6,8-Trisubstituted 3-hydroxychromone derivatives as fluorophores for live-cell imaging.

7-(Benzofuran-2-yl)-7-deazadeoxyguanosine as a fluorescence turn-ON probe for single-strand DNA binding protein

8-Triazolylpurines: Towards Fluorescent Inhibitors of the MDM2/p53 Interaction

A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos

A Fluorescent Kinase Inhibitor that Exhibits Diagnostic Changes in Emission upon Binding

A Single-Cell Study of a Highly Effective Hog1 Inhibitor for in Situ Yeast Cell Manipulation

An acido- and photochromic molecular device that mimics triode action

Application of a peptide-based assay to characterize inhibitors targeting protein kinases from yeast

Arsenic Directly Binds to and Activates the Yeast AP-1-Like Transcription Factor Yap8.

Carbon- and oxygen-centered radicals are equally important haptens of allylic hydroperoxides in allergic contact dermatitis

Characterization of interactions and pharmacophore development for DFG-out inhibitors to RET tyrosine kinase

Characterization of photophysical and base-mimicking properties of a novel fluorescent adenine analogue in DNA. ⬇️

Chroman-4-one and chromone based somatostatin β-turn mimetics.

Chromo-pharmacophores: photochromic diarylmaleimide inhibitors for sirtuins

Defects in the calcium-binding region drastically affect the cadherin-like domains of RET tyrosine kinase.

Design, Synthesis and Evaluation of 2,5-Diketopiperazines as Inhibitors of the MDM2-p53 Interaction

Design, Synthesis and Inhibitory Activity of Photoswitchable RET Kinase Inhibitors

Design, synthesis and characterization of a highly effective inhibitor for analog-sensitive (as) kinases

Design, synthesis, and biological evaluation of chromone-based p38 MAP kinase inhibitors

Design, synthesis, and characterization of a highly effective Hog1 inhibitor: a powerful tool for analyzing MAP kinase signaling in yeast

Determination of primary sequence specificity of Arabidopsis MAPKs MPK3 and MPK6 leads to identification of new substrates.

Development of bright fluorescent quadracyclic adenine analogues: TDDFT-calculation supported rational design

Diffusion of reagents in macrobeads

Discovering New Classes of Brugia malayi Asparaginyl-tRNA Synthetase Inhibitors and Relating Specificity to Conformational Change

Efficient synthesis of 2,5-diketopiperazines using microwave assisted heating

Enhanced microwave-assisted method for on-bead disulfide bond formation: Synthesis of α-conotoxin MII

Flexibility is important for inhibition of the MDM2/p53 protein-protein interaction by cyclic β-hairpins

Fluorescent nucleobase analogues for base-base FRET in nucleic acids: synthesis, photophysics and applications.

Improving the economics of NASH/NAFLD treatment through the use of systems biology

Inhibitors and promoters of tubulin polymerization: synthesis and biological evaluation of chalcones and related dienones as potential anticancer agents

Interbase FRET in RNA: from A to Z

KHMDS enhanced SmI(2)-mediated reformatsky type alpha-cyanation

Lighting Up DNA with the Environment-Sensitive Bright Adenine Analogue qAN4

Method for activation and recycling of trityl resins

Microwave-assisted solid-phase synthesis of 2,5-diketopiperazines: solvent and resin dependence

NMR-based substrate analog docking to Escherichia coli peptidyl-tRNA hydrolase

Network analyses identify liver-specific targets for treating liver diseases

Palladium on carbon encapsulated in POEPOP(1500): a resin-supported catalyst for hydrogenation reactions

Pentacyclic adenine: a versatile and exceptionally bright fluorescent DNA base analogue

Peroxiredoxin promotes longevity and H2O2-resistance in yeast through redox-modulation of protein kinase A

Positional scanning peptide libraries for kinase substrate specificity determinations: straightforward and reproducible synthesis using pentafluorophenyl esters

Preparation of 3-substituted-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-4-amines as RET kinase inhibitors

Pulse-shaped two-photon excitation of a fluorescent base analogue approaches single-molecule sensitivity

Role of the subunit composition of central nicotinic acetylcholine receptors for the stimulatory and dopamine-enhancing effects of ethanol

SPOCC-194, a new high functional group density PEG-based resin for solid-phase organic synthesis

Second-generation fluorescent quadracyclic adenine analogues: environment-responsive probes with enhanced brightness

Selective inhibition of RET mediated cell proliferation in vitro by the kinase inhibitor SPP86. ⬇️

Shining New Light on the Spiropyran Photoswitch: A Photocage Decides between cis- trans or Spiro-Merocyanine Isomerization

Short cut to 1,2,3-triazole-based p38 MAP kinase inhibitorsvia [3+2]-cycloaddition chemistry

Solid-Phase Peptide Synthesis in Water Using Microwave-Assisted Heating

Structural Insights into the Polyphyletic Origins of Glycyl tRNA Synthetases

Structural influence on radical formation and sensitizing capacity of alkylic limonene hydroperoxide analogues in allergic contact dermatitis

Synthesis and Photophysical Characterisation of Fluorescent 8-(1H-1,2,3-Triazol-4-yl)adenosine Derivatives

Synthesis and Photophysical Characterization of Azoheteroarenes

Synthesis and photophysical characterisation of new fluorescent triazole adenine analogues

Synthesis of 2'-([1,2,3]triazol-1-yl)-2'-deoxyadenosines

Synthesis of 2,3,6,8-tetrasubstituted chromone scaffolds

Synthesis of 2-alkyl-substituted chromone derivatives using microwave irradiation

Synthesis of 3-(1,2,3-triazol-1-yl)- and 3-(1,2,3-triazol-4-yl)-substituted pyrazolo[3,4-d]pyrimidin-4-amines via click chemistry: potential inhibitors of the Plasmodium falciparum PfPK7 protein kinase

Synthesis of chiral 1,4-disubstituted-1,2,3-triazole derivatives from amino acids

Synthesis of functionalized, unsymmetrical 1,3,4,6-tetrasubstituted 2,5-diketopiperazines

Synthesis, oligonucleotide incorporation and fluorescence properties in DNA of a bicyclic thymine analogue

The biotin repressor: modulation of allostery by corepressor analogs

The unique characteristics of HOG pathway MAPKs in the extremely halotolerant Hortaea werneckii

Toward Complete Sequence Flexibility of Nucleic Acid Base Analogue FRET.

Towards the development of chromone-based MEK1/2 modulators

Validation of regulated protein phosphorylation events in yeast by quantitative mass spectrometry analysis of purified proteins