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List of works by Stephen P. Cobbold

"Infectious" transplantation tolerance.

scientific article

A comprehensive proteomics and genomics analysis reveals novel transmembrane proteins in human platelets and mouse megakaryocytes including G6b-B, a novel immunoreceptor tyrosine-based inhibitory motif protein

scientific article

A key role for TGF-beta signaling to T cells in the long-term acceptance of allografts

scientific article published on 01 September 2007

A rapid solid-phase enzyme-linked binding assay for screening monoclonal antibodies to cell surface antigens

scientific article published on 01 January 1981

A role for Th2 cytokines in the suppression of CD8+ T cell-mediated graft rejection

scientific article published on 01 July 1997

A role for regulatory T cells in acceptance of ESC-derived tissues transplanted across an major histocompatibility complex barrier

scientific article published on October 2010

A simple method for measuring patient anti-globulin responses against isotypic or idiotypic determinants

scientific article published on 01 February 1990

A theoretical framework for self-tolerance and its relevance to therapy of autoimmune disease

article published in 1988

AMPLIFICATION OF NATURAL REGULATORY IMMUNE MECHANISMS FOR TRANSPLANTATION TOLERANCE1

scientific article published on 01 November 1996

Accelerated memory cell homeostasis during T cell depletion and approaches to overcome it.

scientific article published in April 2006

Adoptive Suppression of Erythrocyte Autoantibodies in Lyt-2+Depleted Recipients

scientific article published on 01 January 1989

Advantages of rat monoclonal antibodies

scientific article

Anti-globulin responses to rat and humanized CAMPATH-1 monoclonal antibody used to treat transplant rejection

scientific article published on 01 November 1999

Antibody-induced transplantation tolerance: the role of dominant regulation

scientific article published on January 2003

Approaching Tolerance in Transplantation ⬇️

scientific article published on September 1, 2001

Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells.

scientific article

Biomarkers of transplantation tolerance: more hopeful than helpful?

scientific article published on 6 April 2011

CAMPATH-1 antibodies in stem-cell transplantation

scientific article published on 01 January 2001

CD 4 and CD 8 monoclonal antibody therapy in canine renal allografts

scientific article published on 01 January 1994

CD4 T cells can reject major histocompatibility complex class I-incompatible skin grafts

scientific article published on 01 January 1999

CD4 and CD8 monoclonal antibody therapy: Strategies to prolong renal allograft survival in the dog

scientific article published on 01 November 1993

CD4 monoclonal antibody pairs for immunosuppression and tolerance induction

scientific article published on 01 August 1987

CD73 and adenosine generation in the creation of regulatory microenvironments ⬇️

scientific article published on January 1, 2013

CD8+ T-Cell depletion and rapamycin synergize with combined coreceptor/stimulation blockade to induce robust limb allograft tolerance in mice

scientific article

Characterization of effector cells of graft vs leukemia following allogeneic bone marrow transplantation in mice inoculated with murine B-cell leukemia

scientific article published on 01 January 1990

Classical transplantation tolerance in the adult: the interaction between myeloablation and immunosuppression.

scientific article published in November 1992

Co-receptor and co-stimulation blockade for mixed chimerism and tolerance without myelosuppressive conditioning

scientific article published on 25 April 2006

Combining regulation with suppression and aiming for tolerance

scientific article published on 01 April 2010

Connecting the mechanisms of T-cell regulation: dendritic cells as the missing link

scientific article published on July 2010

Cultured keratinocyte grafts are recognized, but not rejected by CD8+ T cells in vivo

scientific article published on June 1989

Cutting Edge: Anti-CD154 Therapeutic Antibodies Induce Infectious Transplantation Tolerance

scientific article published on 01 November 2000

DOMINANT TOLERANCE AND LINKED SUPPRESSION INDUCED BY THERAPEUTIC ANTIBODIES DO NOT DEPEND ON FAS-FASL INTERACTIONS1

scientific article published on 01 April 2000

Defective fasL reveals immunregulation after costimulation blockade

scientific article published on 01 February 2001

Delay in onset of insulitis in NOD mice following a single injection of CD 4 and CD8 antibodies

scientific article published on 01 February 1988

Depletion of CD4+ and CD8+ cells eliminates immunologic memory of thyroiditogenicity in murine experimental autoimmune thyroiditis.

scientific article published in January 1994

Depletion of L3T4+ and Lyt-2+ cells by rat monoclonal antibodies alters the development of adoptively transferred experimental autoimmune thyroiditis

article

Detection of monoclonal antibodies against cell surface antigens: the use of antiglobulins coupled to red blood cells

scientific article published on 01 January 1984

Different roles for L3T4+ and Lyt 2+ T cell subsets in the control of an acute herpes simplex virus infection of the skin and nervous system

scientific article published in March 1987

Dominant tolerance: activation thresholds for peripheral generation of regulatory T cells

scientific article

Dominant transplantation tolerance impairs CD8+ T cell function but not expansion

scientific article published on 04 November 2002

Dominant transplantation tolerance. Opinion

scientific article published on October 2003

Donor-specific transplantation tolerance: the paradoxical behavior of CD4+CD25+ T cells

scholarly article

Effects of T-lymphocyte depletion on muscle fibrosis in the mdx mouse.

scientific article published on June 2005

Embryonic stem cell-derived tissues are immunogenic but their inherent immune privilege promotes the induction of tolerance

scholarly article

Exploiting tolerance processes in transplantation.

scientific article

Fc-disabled anti-mouse CD40L antibodies retain efficacy in promoting transplantation tolerance.

scientific article published on 8 September 2008

Foxp3 expression is required for the induction of therapeutic tissue tolerance

scientific article published on 17 September 2012

Generation of anergic and regulatory T cells following prolonged exposure to a harmless antigen

scientific article published in May 2004

Generation of anti-inflammatory adenosine byleukocytes is regulated by TGF-β

scientific article published on 06 September 2011

Guiding Postablative Lymphocyte Reconstitution as a Route Toward Transplantation Tolerance

scientific article published on 19 May 2014

HIGH DOSE BONE MARROW TRANSPLANTATION INDUCES DELETION OF ANTIGEN-SPECIFIC T CELLS IN A FAS-INDEPENDENT MANNER1

scientific article published on 01 April 2000

Harnessing FOXP3+ regulatory T cells for transplantation tolerance.

scientific article published on April 2014

How do monoclonal antibodies induce tolerance? A role for infectious tolerance?

Humanised monoclonal antibody therapy for rheumatoid arthritis

scientific article published in The Lancet

IL-10-conditioned dendritic cells, decommissioned for recruitment of adaptive immunity, elicit innate inflammatory gene products in response to danger signals

scientific journal article

Identification of regulatory T cells in tolerated allografts

scientific article

Immune privilege induced by regulatory T cells in transplantation tolerance

scientific article published on October 2006

Immunohistological screening in the selection of monoclonal antibodies: the use of isotype-specific antiglobulins

scientific article published on 01 April 1984

Immunomodulation of dog islets using a cocktail of monoclonal antibodies ⬇️

scientific article published on 01 January 1992

Immunosuppression of canine renal allograft recipients by CD4 and CD8 monoclonal antibodies.

scientific article published in March 1994

Inducing a tolerogenic microenvironment within tissues.

scientific article

Induction of Regulatory T Cells and Dominant Tolerance by Dendritic Cells Incapable of Full Activation

scientific article published on 01 July 2007

Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants

scientific article published in May 2004

Induction of tolerance in peripheral T cells with monoclonal antibodies.

scientific article

Infectious tolerance ⬇️

scientific article published on October 1, 1998

Infectious tolerance and the long-term acceptance of transplanted tissue

scientific article published on August 2006

Infectious tolerance via the consumption of essential amino acids and mTOR signaling

scientific article published on 30 June 2009

Isolation and expression of cDNA encoding the canine CD4 and CD8α antigens

scientific article published on 01 March 1994

Isolation of low-frequency class-switch variants from rat hybrid myelomás

scientific article published on 01 October 1987

Key role of the GITR/GITRLigand pathway in the development of murine autoimmune diabetes: a potential therapeutic target

scientific article (publication date: 20 November 2009)

Leukaemic relapse after Campath 1-treated bone-marrow transplantation for leukaemia

scientific article published on 01 January 1987

MS4A4B is a GITR-associated membrane adapter, expressed by regulatory T cells, which modulates T cell activation

scientific article

Mechanisms in CD4 antibody-mediated transplantation tolerance: kinetics of induction, antigen dependency and role of regulatory T cells.

scientific article

Mechanisms of monoclonal antibody-facilitated tolerance induction: a possible role for the CD4 (L3T4) and CD11a (LFA-1) molecules in self-non-self discrimination

scientific article published on 01 July 1988

Mechanisms of protection induced by attenuated simian immunodeficiency virus. II. Lymphocyte depletion does not abrogate protection.

scientific article published in September 1998

Monoclonal antibodies as agents to reinduce tolerance in autoimmunity.

scientific article published on April 1992

Monoclonal antibodies that define canine homologues of human CD antigens: summary of the First International Canine Leukocyte Antigen Workshop (CLAW)

scientific article published on 01 March 1994

Monoclonal antibodies to promote marrow engraftment and tissue graft tolerance

scientific article published in Nature

Monoclonal-Antibody Therapy in Systemic Vasculitis

scientific article published on 01 July 1990

Monoclonals and marrow transplants

scientific article published in October 1986

Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells

scientific journal article

New trends in immunosuppression

scientific article published on 01 January 2005

Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression

scientific article published on 15 June 2009

Regulating the immune response to transplants. a role for CD4+ regulatory cells?

scientific article

Regulation and privilege in transplantation tolerance.

scientific article published on 6 September 2008

Regulatory T cells and dendritic cells in transplantation tolerance: molecular markers and mechanisms

scientific article published in December 2003

Regulatory T cells and organ transplantation

scientific article published on April 2004

Regulatory T cells and transplantation tolerance.

scientific article published in July 2013

Regulatory T cells in the induction and maintenance of peripheral transplantation tolerance

scientific article

Regulatory T cells in transplantation

scientific article published on 14 February 2006

Regulatory T cells overexpress a subset of Th2 gene transcripts

scientific article

Regulatory T cells: context matters

scientific article published in May 2009

Rejecting Minors—It's All in the Presentation ⬇️

scientific article published on January 27, 2011

Reprogramming the immune system: co-receptor blockade as a paradigm for harnessing tolerance mechanisms

scientific article

Resistance to experimental autoimmune thyroiditis: L3T4+ cells as mediators of both thyroglobulin-activated and TSH-induced suppression.

scientific article published in April 1989

SAGE Analysis of Cell Types Involved in Tolerance Induction

STRAIN VARIATION IN SUSCEPTIBILITY TO MONOCLONAL ANTIBODY-INDUCED TRANSPLANTATION TOLERANCE1

scientific article published on 01 June 1997

Segregation of mouse hemopoietic progenitor cells using the monoclonal antibody, YBM/42

scientific article published on 01 April 1983

Serial analysis of gene expression provides new insights into regulatory T cells

scientific article published on August 2003

Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase

scientific article published on 6 September 2004

Suppression in murine experimental autoimmune thyroiditis: in vivo inhibition of CD4+ T cell-mediated resistance by a nondepleting rat CD4 monoclonal antibody

scientific article published in November 1991

Sustained suppression by Foxp3+ regulatory T cells is vital for infectious transplantation tolerance

scientific article

T cell tolerance in transplantation: possibilities for therapeutic intervention.

scientific article

T cell tolerance induced by therapeutic antibodies

scientific article

TGF-β in transplantation tolerance

scientific article published on 10 August 2011

TOLERANCE AND SUPPRESSION IN A PRIMED IMMUNE SYSTEM1

scientific article published on 01 December 1996

Th17 cells induce a distinct graft rejection response that does not require IL-17A.

scientific article

The immunology of companion animals: reagents and therapeutic strategies with potential veterinary and human clinical applications.

scientific article published on August 1994

The improved lytic function andin vivo efficacy of monovalent monoclonal CD3 antibodies

scientific article published on 01 February 1989

The induction of skin graft tolerance in major histocompatibility complex-mismatched or primed recipients: primed T cells can be tolerized in the periphery with anti-CD4 and anti-CD8 antibodies

scientific article published in December 1990

The use of monoclonal antibodies to achieve immunological tolerance

scientific article published on 01 June 1993

The use of monoclonal antibodies to achieve immunological tolerance.

scientific article

Therapeutic aspects of tolerance.

scientific article

Therapeutic potential of monovalent monoclonal antibodies

scientific article published in Nature

Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

scientific article published in Nature

Tmem176B and Tmem176A are associated with the immature state of dendritic cells

scientific journal article

Tolerance Induction with CD4 Monoclonal Antibodies ⬇️

scientific article published on 01 January 1998

Tolerance in the mouse to major histocompatibility complex-mismatched heart allografts, and to rat heart xenografts, using monoclonal antibodies to CD4 and CD8

scientific article published on 01 March 1992

Tolerance induction in the adult using monoclonal antibodies to CD4, CD8, and CD11a (LFA-1)

scientific article published on 01 January 1989

Tolerogenicity is not an absolute property of a dendritic cell

scientific article published in June 2010

Translating Tolerogenic Therapies to the Clinic - Where Do We Stand and What are the Barriers?

scientific article published on 12 October 2012

What can be done to prevent graft versus host disease?

scientific article published on October 1994

mTOR signalling and metabolic regulation of T cell differentiation

scientific article published on 15 September 2010

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