List of works - Alexander Dityatev

5-HT7 receptor is coupled to G alpha subunits of heterotrimeric G12-protein to regulate gene transcription and neuronal morphology.

scientific article

5-HT7 receptor shapes spinogenesis in cortical and striatal neurons: An Editorial Highlight for 'Serotonin 5-HT7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons'.

scientific article published on 24 March 2017

A correlative physiological and morphological analysis of monosynaptically connected propriospinal axon-motoneuron pairs in the lumbar spinal cord of frogs

scientific article published in January 2001

A homeostatic model of neuronal firing governed by feedback signals from the extracellular matrix

scientific article

A novel versatile hybrid infusion-multielectrode recording (HIME) system for acute drug delivery and multisite acquisition of neuronal activity in freely moving mice

scientific article published on 5 November 2015

A shift in the mechanisms controlling hippocampal engram formation during brain maturation

scientific article published on 04 May 2023

A synthetic synaptic organizer protein restores glutamatergic neuronal circuits

scientific article published on 01 August 2020

Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes

scientific article

Activity-dependent formation and functions of chondroitin sulfate-rich extracellular matrix of perineuronal nets

scientific article

Age-dependent loss of parvalbumin-expressing hippocampal interneurons in mice deficient in CHL1, a mental retardation and schizophrenia susceptibility gene

scientific article published on 18 August 2015

Ameliorating effects of preadolescent aniracetam treatment on prenatal ethanol-induced impairment in AMPA receptor activity

scientific article published on 14 August 2007

Amelioration of Tau pathology and memory deficits by targeting 5-HT7 receptor

scientific article published on 22 August 2020

Amygdala, long-term potentiation, and fear conditioning

scientific article

Amyloid precursor protein and amyloid β-peptide bind to ATP synthase and regulate its activity at the surface of neural cells

article by C Schmidt et al published 28 August 2007 in Molecular Psychiatry

Analysis of neural cell functions in gene knockout mice: electrophysiological investigation of synaptic plasticity in acute hippocampal slices

scientific article published on January 2006

Attenuated palmitoylation of serotonin receptor 5-HT1A affects receptor function and contributes to depression-like behaviors

scientific article published on 02 September 2019

Attenuation of the extracellular matrix restores microglial activity during the early stage of amyloidosis

scientific article published on 31 August 2020

Beta-amyloid and glutamate receptors

scientific article published on 19 March 2008

Bi-directional astrocytic regulation of neuronal activity within a network.

scientific article

Brain circuitry outside the synaptic cleft

scientific article published on October 2014

Cell adhesion molecules in synapse formation.

scientific article published in October 2004

Combining principal component and spectral analyses with the method of moments in studies of quantal transmission

scientific article published in December 2003

Comparison of the topology and growth rules of motoneuronal dendrites

article

Compartmentalization from the outside: the extracellular matrix and functional microdomains in the brain

scientific article

Conditional ablation of the neural cell adhesion molecule reduces precision of spatial learning, long-term potentiation, and depression in the CA1 subfield of mouse hippocampus.

scientific article published in February 2004

Cosignaling of NCAM via lipid rafts and the FGF receptor is required for neuritogenesis

scientific article published on 29 April 2002

Current microscopic methods for the neural ECM analysis

scientific article

Decreased anxiety, altered place learning, and increased CA1 basal excitatory synaptic transmission in mice with conditional ablation of the neural cell adhesion molecule L1.

scientific article published on November 2003

Developmental nicotine exposure induced alterations in behavior and glutamate receptor function in hippocampus

scientific article

Electroporation-based gene transfer for efficient transfection of neural precursor cells

scientific article published in August 2005

Enhanced perisomatic inhibition and impaired long-term potentiation in the CA1 region of juvenile CHL1-deficient mice

scientific article

Evaluation of Toxicity and Neural Uptake In Vitro and In Vivo of Superparamagnetic Iron Oxide Nanoparticles

article

Extracellular matrix alterations in the ketamine model of schizophrenia

scientific article

Extracellular matrix and synaptic functions.

scientific article published on January 2006

Extracellular matrix in plasticity and epileptogenesis

scientific article published on August 2008

Extracellular matrix molecules and synaptic plasticity

scientific article

Extracellular matrix molecules, their receptors, and secreted proteases in synaptic plasticity

scientific article

Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R

scientific article published on 08 December 2021

Fibroblast growth factor-regulated palmitoylation of the neural cell adhesion molecule determines neuronal morphogenesis

scientific article

Fibronectin domains of extracellular matrix molecule tenascin-C modulate hippocampal learning and synaptic plasticity

scientific article published in September 2002

Fine structure analysis of perineuronal nets in the ketamine model of schizophrenia

scientific article published on 08 June 2020

Functional consequences of the interactions among the neural cell adhesion molecule NCAM, the receptor tyrosine kinase TrkB, and the inwardly rectifying K+ channel KIR3.3.

scientific article published on 6 July 2010

Genetic ablation of tenascin-C expression leads to abnormal hippocampal CA1 structure and electrical activity in vivo

scientific article published in December 2009

HDAC1 links early life stress to schizophrenia-like phenotypes

scientific article

Heparin/heparan sulfates bind to and modulate neuronal L-type (Cav1.2) voltage-dependent Ca(2+) channels

scientific article published on 10 August 2015

Heterodimerization of serotonin receptors 5-HT1A and 5-HT7 differentially regulates receptor signalling and trafficking

scientific article

Hippocampal metaplasticity induced by deficiency in the extracellular matrix glycoprotein tenascin-R

scientific article

Impairment of L-type Ca2+ channel-dependent forms of hippocampal synaptic plasticity in mice deficient in the extracellular matrix glycoprotein tenascin-C.

scientific article published on August 2002

Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses

scientific article

Improved reversal learning and working memory and enhanced reactivity to novelty in mice with enhanced GABAergic innervation in the dentate gyrus

scientific article published in March 2010

In vivo synaptic plasticity in the dentate gyrus of mice deficient in the neural cell adhesion molecule NCAM or its polysialic acid

scientific article

Integration of excitatory postsynaptic potentials in dendrites of motoneurons of rat spinal cord slice cultures

article

Ligand-receptor interactions. Multidimensional mathematical method of analysis.

scientific article published on November 1993

Limits of quantal analysis reliability: quantal and unimodal constraints and setting of confidence intervals for quantal size

scientific article published in October 1993

Matrix metalloproteinase-9 and non-amyloidogenic pathway of amyloid precursor protein processing

Memory enhancement by ferulic acid ester across species

scientific article published on 24 October 2018

Mice deficient for the extracellular matrix glycoprotein tenascin-r show physiological and structural hallmarks of increased hippocampal excitability, but no increased susceptibility to seizures in the pilocarpine model of epilepsy

scientific article published in January 2004

Mice deficient in the polysialyltransferase ST8SiaIV/PST-1 allow discrimination of the roles of neural cell adhesion molecule protein and polysialic acid in neural development and synaptic plasticity.

scientific article published in July 2000

Modeling of the quantal release at interneuronal synapses: analysis of permissible values of model moments

scientific article published in July 1992

Modification of extracellular matrix by enzymatic removal of chondroitin sulfate and by lack of tenascin-R differentially affects several forms of synaptic plasticity in the hippocampus

scientific journal article

Modulation of network activity and induction of homeostatic synaptic plasticity by enzymatic removal of heparan sulfates

scientific article published on October 2014

Modulation of synaptic transmission and plasticity by cell adhesion and repulsion molecules

scientific article published on August 2008

Molecular signals of plasticity at the tetrapartite synapse ⬇️

scientific article published on February 1, 2011

Morphogenic signaling in neurons via neurotransmitter receptors and small GTPases

scientific article published on June 2007

NCAM-induced neurite outgrowth depends on binding of calmodulin to NCAM and on nuclear import of NCAM and fak fragments.

scientific article published on August 2010

NCAM180 and glutamate receptor subtypes in potentiated spine synapses: an immunogold electron microscopic study

scientific article published in December 2003

Natural variability in the number of dendritic segments: model-based inferences about branching during neurite outgrowth

scientific article published on October 1997

Neural ECM and epilepsy

scientific article

Neural ECM molecules in synaptic plasticity, learning, and memory

scientific article

Neural cell adhesion molecule ablation in mice causes hippocampal dysplasia and loss of septal cholinergic neurons

Neural cell adhesion molecule promotes accumulation of TGN organelles at sites of neuron-to-neuron contacts

scientific article

Neural cell adhesion molecule-associated polysialic acid inhibits NR2B-containing N-methyl-D-aspartate receptors and prevents glutamate-induced cell death

scientific article published on 20 September 2006

Neural cell adhesion molecule-associated polysialic acid potentiates alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor currents

scientific article

Neural cell adhesion molecule-associated polysialic acid regulates synaptic plasticity and learning by restraining the signaling through GluN2B-containing NMDA receptors.

scientific article

PSA-NCAM: synaptic functions mediated by its interactions with proteoglycans and glutamate receptors

scientific article published on 25 January 2012

Physicochemical properties of signal receptor domains as the basis for sequence comparison

scientific article published in January 1991

Polysialic Acid in Brain Development and Synaptic Plasticity ⬇️

scientific article published on January 1, 2015

Polysialylated neural cell adhesion molecule is involved in induction of long-term potentiation and memory acquisition and consolidation in a fear-conditioning paradigm.

scientific article

Polysialylated neural cell adhesion molecule promotes remodeling and formation of hippocampal synapses.

scientific article published in October 2004

Postnatal aniracetam treatment improves prenatal ethanol induced attenuation of AMPA receptor-mediated synaptic transmission

scientific article

Potentiated amygdaloid auditory-evoked potentials and freezing behavior after fear conditioning in mice

scientific article published in November 2001

Potentiation of amygdaloid and hippocampal auditory-evoked potentials in a discriminatory fear-conditioning task in mice as a function of tone pattern and context

scientific article published in August 2003

Preface. Brain extracellular matrix in health and disease

scientific article published in January 2014

Quantal analysis based on spectral methods

scientific article published in November 1994

Rapid and efficient electroporation-based gene transfer into primary dissociated neurons

scientific article

Rapid generation of functional dopaminergic neurons from human induced pluripotent stem cells through a single-step procedure using cell lineage transcription factors

scientific article published on 8 May 2013

Recognition molecule associated carbohydrate inhibits postsynaptic GABA(B) receptors: a mechanism for homeostatic regulation of GABA release in perisomatic synapses

scientific article published on October 2003

Reduced GABAergic transmission and number of hippocampal perisomatic inhibitory synapses in juvenile mice deficient in the neural cell adhesion molecule L1.

scientific article published on May 2004

Reduced perisomatic inhibition, increased excitatory transmission, and impaired long-term potentiation in mice deficient for the extracellular matrix glycoprotein tenascin-R

scientific journal article

Reduced reactivity to novelty, impaired social behavior, and enhanced basal synaptic excitatory activity in perforant path projections to the dentate gyrus in young adult mice deficient in the neural cell adhesion molecule CHL1.

scientific article

Regulation of extrasynaptic signaling by polysialylated NCAM: Impact for synaptic plasticity and cognitive functions

scientific article published on 16 November 2016

Reliability of spike propagation in arborizations of dorsal root fibers studied by analysis of postsynaptic potentials mediated by electrotonic coupling in the frog spinal cord

scientific article published on 01 November 1996

Remodeling of extracellular matrix and epileptogenesis

scientific article published in July 2010

Remote control of induced dopaminergic neurons in parkinsonian rats.

scientific article

Restoration of synaptic plasticity and learning in young and aged NCAM-deficient mice by enhancing neurotransmission mediated by GluN2A-containing NMDA receptors.

scientific article published in February 2012

Retarded kindling progression in mice deficient in the extracellular matrix glycoprotein tenascin-R.

scientific article published on 30 October 2008

SHANK3 gene mutations associated with autism facilitate ligand binding to the Shank3 ankyrin repeat region

scientific article published on 29 July 2013

Seizure-like activity in hyaluronidase-treated dissociated hippocampal cultures

scientific article published on 12 September 2013

Serotonin 5-HT4 receptor boosts functional maturation of dendritic spines via RhoA-dependent control of F-actin

scientific article published on 14 February 2020

Sialyltransferase ST8Sia-II assembles a subset of polysialic acid that directs hippocampal axonal targeting and promotes fear behavior

scientific article

Single channel recordings from synaptosomal AMPA receptors

scientific article

Structural and physiological properties of connections between individual reticulospinal axons and lumbar motoneurons of the frog

scientific article published in February 2001

Synaptic Remodeling Depends on Signaling between Serotonin Receptors and the Extracellular Matrix

scientific article published in May 2017

Synaptic Strength as a Function of Post- versus Presynaptic Expression of the Neural Cell Adhesion Molecule NCAM

scientific article published on 01 April 2000

Synaptic cell adhesion molecules

scientific article published on January 2012

Synaptic differentiation of single descending fibers studied by triple intracellular recording in the frog spinal cord

scientific article published on 01 February 1998

Synaptic plasticity in dissociated hippocampal cultures: pre- and postsynaptic contributions

scientific article published in May 1997

Targeting of ECM molecules and their metabolizing enzymes and receptors for the treatment of CNS diseases

scientific article

Targeting the neural extracellular matrix in neurological disorders

scientific article published on 04 September 2013

Tenascin-R promotes assembly of the extracellular matrix of perineuronal nets via clustering of aggrecan

scientific article published on October 2014

The 14-3-3ζ protein binds to the cell adhesion molecule L1, promotes L1 phosphorylation by CKII and influences L1-dependent neurite outgrowth

scientific article (publication date: 18 October 2010)

The dual role of the extracellular matrix in synaptic plasticity and homeostasis

scientific article published on 14 October 2010

The extracellular matrix and synapses

scientific article published on 10 June 2006

The extracellular matrix molecule hyaluronic acid regulates hippocampal synaptic plasticity by modulating postsynaptic L-type Ca(2+) channels

scientific article

The extracellular matrix molecule tenascin-R and its HNK-1 carbohydrate modulate perisomatic inhibition and long-term potentiation in the CA1 region of the hippocampus

scientific article published on 01 September 2000

The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity

scientific journal article

The magic of synaptogenesis. Meeting on spinogenesis and synaptic plasticity

scientific article published in December 2004

The neural cell adhesion molecule regulates cell-surface delivery of G-protein-activated inwardly rectifying potassium channels via lipid rafts.

scientific article published in August 2002

Transgenic mice overexpressing the extracellular domain of NCAM are impaired in working memory and cortical plasticity

scientific article

Transient activity of excitatory Cl- channels in Chara: evidence for quantal release of a gating factor.

scientific article published in June 1998

With a little help from EphA3 and polysialic acid: ectodomain shedding of NCAM is gaining momentum.

scientific article

List of works by Alexander Dityatev

5-HT7 receptor is coupled to G alpha subunits of heterotrimeric G12-protein to regulate gene transcription and neuronal morphology.

5-HT7 receptor shapes spinogenesis in cortical and striatal neurons: An Editorial Highlight for 'Serotonin 5-HT7 receptor increases the density of dendritic spines and facilitates synaptogenesis in forebrain neurons'.

A correlative physiological and morphological analysis of monosynaptically connected propriospinal axon-motoneuron pairs in the lumbar spinal cord of frogs

A homeostatic model of neuronal firing governed by feedback signals from the extracellular matrix

A novel versatile hybrid infusion-multielectrode recording (HIME) system for acute drug delivery and multisite acquisition of neuronal activity in freely moving mice

A shift in the mechanisms controlling hippocampal engram formation during brain maturation

A synthetic synaptic organizer protein restores glutamatergic neuronal circuits

Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes

Activity-dependent formation and functions of chondroitin sulfate-rich extracellular matrix of perineuronal nets

Age-dependent loss of parvalbumin-expressing hippocampal interneurons in mice deficient in CHL1, a mental retardation and schizophrenia susceptibility gene

Ameliorating effects of preadolescent aniracetam treatment on prenatal ethanol-induced impairment in AMPA receptor activity

Amelioration of Tau pathology and memory deficits by targeting 5-HT7 receptor

Amygdala, long-term potentiation, and fear conditioning

Amyloid precursor protein and amyloid β-peptide bind to ATP synthase and regulate its activity at the surface of neural cells

Analysis of neural cell functions in gene knockout mice: electrophysiological investigation of synaptic plasticity in acute hippocampal slices

Attenuated palmitoylation of serotonin receptor 5-HT1A affects receptor function and contributes to depression-like behaviors

Attenuation of the extracellular matrix restores microglial activity during the early stage of amyloidosis

Beta-amyloid and glutamate receptors

Bi-directional astrocytic regulation of neuronal activity within a network.

Brain circuitry outside the synaptic cleft

Cell adhesion molecules in synapse formation.

Combining principal component and spectral analyses with the method of moments in studies of quantal transmission

Comparison of the topology and growth rules of motoneuronal dendrites

Compartmentalization from the outside: the extracellular matrix and functional microdomains in the brain

Conditional ablation of the neural cell adhesion molecule reduces precision of spatial learning, long-term potentiation, and depression in the CA1 subfield of mouse hippocampus.

Cosignaling of NCAM via lipid rafts and the FGF receptor is required for neuritogenesis

Current microscopic methods for the neural ECM analysis

Decreased anxiety, altered place learning, and increased CA1 basal excitatory synaptic transmission in mice with conditional ablation of the neural cell adhesion molecule L1.

Developmental nicotine exposure induced alterations in behavior and glutamate receptor function in hippocampus

Electroporation-based gene transfer for efficient transfection of neural precursor cells

Enhanced perisomatic inhibition and impaired long-term potentiation in the CA1 region of juvenile CHL1-deficient mice

Evaluation of Toxicity and Neural Uptake In Vitro and In Vivo of Superparamagnetic Iron Oxide Nanoparticles

Extracellular matrix alterations in the ketamine model of schizophrenia

Extracellular matrix and synaptic functions.

Extracellular matrix in plasticity and epileptogenesis

Extracellular matrix molecules and synaptic plasticity

Extracellular matrix molecules, their receptors, and secreted proteases in synaptic plasticity

Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R

Fibroblast growth factor-regulated palmitoylation of the neural cell adhesion molecule determines neuronal morphogenesis

Fibronectin domains of extracellular matrix molecule tenascin-C modulate hippocampal learning and synaptic plasticity

Fine structure analysis of perineuronal nets in the ketamine model of schizophrenia

Functional consequences of the interactions among the neural cell adhesion molecule NCAM, the receptor tyrosine kinase TrkB, and the inwardly rectifying K+ channel KIR3.3.

Genetic ablation of tenascin-C expression leads to abnormal hippocampal CA1 structure and electrical activity in vivo

HDAC1 links early life stress to schizophrenia-like phenotypes

Heparin/heparan sulfates bind to and modulate neuronal L-type (Cav1.2) voltage-dependent Ca(2+) channels

Heterodimerization of serotonin receptors 5-HT1A and 5-HT7 differentially regulates receptor signalling and trafficking

Hippocampal metaplasticity induced by deficiency in the extracellular matrix glycoprotein tenascin-R

Impairment of L-type Ca2+ channel-dependent forms of hippocampal synaptic plasticity in mice deficient in the extracellular matrix glycoprotein tenascin-C.

Importance of Shank3 protein in regulating metabotropic glutamate receptor 5 (mGluR5) expression and signaling at synapses

Improved reversal learning and working memory and enhanced reactivity to novelty in mice with enhanced GABAergic innervation in the dentate gyrus

In vivo synaptic plasticity in the dentate gyrus of mice deficient in the neural cell adhesion molecule NCAM or its polysialic acid

Integration of excitatory postsynaptic potentials in dendrites of motoneurons of rat spinal cord slice cultures

Ligand-receptor interactions. Multidimensional mathematical method of analysis.

Limits of quantal analysis reliability: quantal and unimodal constraints and setting of confidence intervals for quantal size

Matrix metalloproteinase-9 and non-amyloidogenic pathway of amyloid precursor protein processing

Memory enhancement by ferulic acid ester across species

Mice deficient for the extracellular matrix glycoprotein tenascin-r show physiological and structural hallmarks of increased hippocampal excitability, but no increased susceptibility to seizures in the pilocarpine model of epilepsy

Mice deficient in the polysialyltransferase ST8SiaIV/PST-1 allow discrimination of the roles of neural cell adhesion molecule protein and polysialic acid in neural development and synaptic plasticity.

Modeling of the quantal release at interneuronal synapses: analysis of permissible values of model moments

Modification of extracellular matrix by enzymatic removal of chondroitin sulfate and by lack of tenascin-R differentially affects several forms of synaptic plasticity in the hippocampus

Modulation of network activity and induction of homeostatic synaptic plasticity by enzymatic removal of heparan sulfates

Modulation of synaptic transmission and plasticity by cell adhesion and repulsion molecules

Molecular signals of plasticity at the tetrapartite synapse ⬇️

Morphogenic signaling in neurons via neurotransmitter receptors and small GTPases

NCAM-induced neurite outgrowth depends on binding of calmodulin to NCAM and on nuclear import of NCAM and fak fragments.

NCAM180 and glutamate receptor subtypes in potentiated spine synapses: an immunogold electron microscopic study

Natural variability in the number of dendritic segments: model-based inferences about branching during neurite outgrowth

Neural ECM and epilepsy

Neural ECM molecules in synaptic plasticity, learning, and memory

Neural cell adhesion molecule ablation in mice causes hippocampal dysplasia and loss of septal cholinergic neurons

Neural cell adhesion molecule promotes accumulation of TGN organelles at sites of neuron-to-neuron contacts

Neural cell adhesion molecule-associated polysialic acid inhibits NR2B-containing N-methyl-D-aspartate receptors and prevents glutamate-induced cell death

Neural cell adhesion molecule-associated polysialic acid potentiates alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptor currents

Neural cell adhesion molecule-associated polysialic acid regulates synaptic plasticity and learning by restraining the signaling through GluN2B-containing NMDA receptors.

PSA-NCAM: synaptic functions mediated by its interactions with proteoglycans and glutamate receptors

Physicochemical properties of signal receptor domains as the basis for sequence comparison

Polysialic Acid in Brain Development and Synaptic Plasticity ⬇️

Polysialylated neural cell adhesion molecule is involved in induction of long-term potentiation and memory acquisition and consolidation in a fear-conditioning paradigm.

Polysialylated neural cell adhesion molecule promotes remodeling and formation of hippocampal synapses.