List of works - Pablo A. Iglesias

14-3-3 coordinates microtubules, Rac, and myosin II to control cell mechanics and cytokinesis

scientific article

A Systems Biology View of Adaptation in Sensory Mechanisms ⬇️

scientific article published on January 1, 2012

A computational model for the formation of lamin-B mitotic spindle envelope and matrix.

scientific article published on June 2014

A framework for designing and analyzing binary decision-making strategies in cellular systems.

scientific article published on March 2012

A mechanosensory system governs myosin II accumulation in dividing cells ⬇️

scientific article published on February 29, 2012

A method for determining the robustness of bio-molecular oscillator models

scientific article published on 21 September 2009

A modeling framework describing the enzyme regulation of membrane lipids underlying gradient perception in Dictyostelium cells.

scientific article published in July 2004

A modelling framework describing the enzyme regulation of membrane lipids underlying gradient perception in Dictyostelium cells II: input-output analysis

scientific article published in August 2005

Altering the threshold of an excitable signal transduction network changes cell migratory modes

scientific article published on 27 March 2017

An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration.

scientific article

An information-theoretic characterization of the optimal gradient sensing response of cells

scientific article

An integrative approach to understanding mechanosensation.

scientific article published on 25 June 2007

Analysis of the signal transduction properties of a module of spatial sensing in eukaryotic chemotaxis

scientific article published on 01 January 2003

Basic principles of polarity establishment and maintenance. Conference on Mechanisms of Cell Polarity

scientific article published on September 2008

Biased excitable networks: how cells direct motion in response to gradients.

scientific article

Bringing the physical sciences into your cell biology research

scientific article

Cells navigate with a local-excitation, global-inhibition-biased excitable network.

scientific article

Chemical and mechanical stimuli act on common signal transduction and cytoskeletal networks

scientific article

Chemoattractant signaling in dictyostelium discoideum.

scientific article

Chemoattractant signaling in dictyostelium: adaptation and amplification.

scientific article published on 28 February 2012

Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton

scholarly article

Chromosome alignment and segregation regulated by ubiquitination of survivin

scientific article

Control analysis of bacterial chemotaxis signaling.

scientific article published in January 2007

Control theory in biology and medicine : Introduction to the special issue

scientific article published on 01 April 2019

Controlling excitable wave behaviors through the tuning of three parameters

scientific article published on 28 July 2018

Cytokinesis: Robust cell shape regulation.

scientific article

Deconvolution of the cellular force-generating subsystems that govern cytokinesis furrow ingression

scientific article (publication date: 2012)

Disrupting microtubule network immobilizes amoeboid chemotactic receptor in the plasma membrane ⬇️

scientific article published on February 18, 2011

Dynacortin facilitates polarization of chemotaxing cells.

scientific article

Endoplasmic Reticulum Lipid Flux Influences Enterocyte Nuclear Morphology and Lipid-dependent Transcriptional Responses.

scientific article

Ergosterol Regulates Sterol Regulatory Element Binding Protein (SREBP) Cleavage in Fission Yeast ⬇️

scientific article published on October 19, 2010

Excitable behavior in amoeboid chemotaxis.

scientific article published on 11 June 2013

How the mechanobiome drives cell behavior, viewed through the lens of control theory

scientific article published on 02 September 2019

Identifying a static nonlinear structure in a biological system using noisy, sparse data

scientific article

Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation

scientific article published in Nature Communications

Interaction of motility, directional sensing, and polarity modules recreates the behaviors of chemotaxing cells

scientific article

Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assembly

scientific article

Lineage mapping the pre-implantation mouse embryo by two-photon microscopy, new insights into the segregation of cell fates

scientific article

MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast

scientific article published on 18 February 2007

Mechanoaccumulative Elements of the Mammalian Actin Cytoskeleton

scientific article published on 11 May 2016

Mitotic Membrane Helps to Focus and Stabilize the Mitotic Spindle ⬇️

scientific article published on November 17, 2010

Modeling Excitable Dynamics of Chemotactic Networks.

scientific article published in January 2016

Modeling cellular deformations using the level set formalism

scientific article

Molecular mechanisms of cellular mechanosensing

scientific article published on 20 October 2013

Myosin IIB assembly state determines its mechanosensitive dynamics

scientific article published on 17 January 2019

Navigating through models of chemotaxis.

scientific article published on 18 January 2008

Nucleating new branches from old

scientific article

Nucleocytoplasmic shuttling of a GATA transcription factor functions as a development timer.

scientific article

Optimal noise filtering in the chemotactic response of Escherichia coli

scientific article

Positive feedback may cause the biphasic response observed in the chemoattractant-induced response of Dictyostelium cells.

scientific article

Publisher Correction: Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation

scientific article published in Nature Communications

Publisher Correction: Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation

scientific article published on 15 January 2019

Receptor-mediated and intrinsic polarization and their interaction in chemotaxing cells.

scientific article published on 3 November 2006

Regulation of SREBP during hypoxia requires Ofd1-mediated control of both DNA binding and degradation.

scientific article

Robustness analysis of biochemical network models

scientific article published in May 2006

Separation anxiety: Stress, tension and cytokinesis ⬇️

scientific article published on March 31, 2012

Spatial regulation improves antiparallel microtubule overlap during mitotic spindle assembly.

scientific article published on 20 December 2007

Spatial regulation of PI3K signaling during chemotaxis.

scientific article published on September 2009

Targeting Mechanoresponsive Proteins in Pancreatic Cancer: 4-Hydroxyacetophenone Blocks Dissemination and Invasion by Activating MYH14

scientific article published on 29 July 2019

The threshold of an excitable system serves as a control mechanism for noise filtering during chemotaxis

scientific article published on 30 July 2018

Three-dimensional stochastic simulation of chemoattractant-mediated excitability in cells

scientific article published on 14 July 2021

Tools for analyzing cell shape changes during chemotaxis

scientific article published on October 2010

Tools for computational analysis of moving boundary problems in cellular mechanobiology

scientific article published on 10 December 2020

Traveling and standing waves mediate pattern formation in cellular protrusions

scientific article published on 07 August 2020

Two complementary, local excitation, global inhibition mechanisms acting in parallel can explain the chemoattractant-induced regulation of PI(3,4,5)P3 response in dictyostelium cells.

scientific article

Understanding the cooperative interaction between myosin II and actin cross-linkers mediated by actin filaments during mechanosensation

scientific article published on January 2012

Wave patterns organize cellular protrusions and control cortical dynamics

scientific article published on 11 March 2019

tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis

scientific article published on August 2008

List of works by Pablo A. Iglesias

14-3-3 coordinates microtubules, Rac, and myosin II to control cell mechanics and cytokinesis

A Systems Biology View of Adaptation in Sensory Mechanisms ⬇️

A computational model for the formation of lamin-B mitotic spindle envelope and matrix.

A framework for designing and analyzing binary decision-making strategies in cellular systems.

A mechanosensory system governs myosin II accumulation in dividing cells ⬇️

A method for determining the robustness of bio-molecular oscillator models

A modeling framework describing the enzyme regulation of membrane lipids underlying gradient perception in Dictyostelium cells.

A modelling framework describing the enzyme regulation of membrane lipids underlying gradient perception in Dictyostelium cells II: input-output analysis

Altering the threshold of an excitable signal transduction network changes cell migratory modes

An excitable signal integrator couples to an idling cytoskeletal oscillator to drive cell migration.

An information-theoretic characterization of the optimal gradient sensing response of cells

An integrative approach to understanding mechanosensation.

Analysis of the signal transduction properties of a module of spatial sensing in eukaryotic chemotaxis

Basic principles of polarity establishment and maintenance. Conference on Mechanisms of Cell Polarity

Biased excitable networks: how cells direct motion in response to gradients.

Bringing the physical sciences into your cell biology research

Cells navigate with a local-excitation, global-inhibition-biased excitable network.

Chemical and mechanical stimuli act on common signal transduction and cytoskeletal networks

Chemoattractant signaling in dictyostelium discoideum.

Chemoattractant signaling in dictyostelium: adaptation and amplification.

Chemoattractant-induced phosphatidylinositol 3,4,5-trisphosphate accumulation is spatially amplified and adapts, independent of the actin cytoskeleton

Chromosome alignment and segregation regulated by ubiquitination of survivin

Control analysis of bacterial chemotaxis signaling.

Control theory in biology and medicine : Introduction to the special issue

Controlling excitable wave behaviors through the tuning of three parameters

Cytokinesis: Robust cell shape regulation.

Deconvolution of the cellular force-generating subsystems that govern cytokinesis furrow ingression

Disrupting microtubule network immobilizes amoeboid chemotactic receptor in the plasma membrane ⬇️

Dynacortin facilitates polarization of chemotaxing cells.

Endoplasmic Reticulum Lipid Flux Influences Enterocyte Nuclear Morphology and Lipid-dependent Transcriptional Responses.

Ergosterol Regulates Sterol Regulatory Element Binding Protein (SREBP) Cleavage in Fission Yeast ⬇️

Excitable behavior in amoeboid chemotaxis.

How the mechanobiome drives cell behavior, viewed through the lens of control theory

Identifying a static nonlinear structure in a biological system using noisy, sparse data

Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation

Interaction of motility, directional sensing, and polarity modules recreates the behaviors of chemotaxing cells

Lamin B counteracts the kinesin Eg5 to restrain spindle pole separation during spindle assembly

Lineage mapping the pre-implantation mouse embryo by two-photon microscopy, new insights into the segregation of cell fates

MAPK-mediated bimodal gene expression and adaptive gradient sensing in yeast

Mechanoaccumulative Elements of the Mammalian Actin Cytoskeleton

Mitotic Membrane Helps to Focus and Stabilize the Mitotic Spindle ⬇️

Modeling Excitable Dynamics of Chemotactic Networks.

Modeling cellular deformations using the level set formalism

Molecular mechanisms of cellular mechanosensing

Myosin IIB assembly state determines its mechanosensitive dynamics

Navigating through models of chemotaxis.

Nucleating new branches from old

Nucleocytoplasmic shuttling of a GATA transcription factor functions as a development timer.

Optimal noise filtering in the chemotactic response of Escherichia coli

Positive feedback may cause the biphasic response observed in the chemoattractant-induced response of Dictyostelium cells.

Publisher Correction: Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation

Publisher Correction: Integrating chemical and mechanical signals through dynamic coupling between cellular protrusions and pulsed ERK activation

Receptor-mediated and intrinsic polarization and their interaction in chemotaxing cells.

Regulation of SREBP during hypoxia requires Ofd1-mediated control of both DNA binding and degradation.

Robustness analysis of biochemical network models

Separation anxiety: Stress, tension and cytokinesis ⬇️

Spatial regulation improves antiparallel microtubule overlap during mitotic spindle assembly.

Spatial regulation of PI3K signaling during chemotaxis.

Targeting Mechanoresponsive Proteins in Pancreatic Cancer: 4-Hydroxyacetophenone Blocks Dissemination and Invasion by Activating MYH14

The threshold of an excitable system serves as a control mechanism for noise filtering during chemotaxis

Three-dimensional stochastic simulation of chemoattractant-mediated excitability in cells

Tools for analyzing cell shape changes during chemotaxis

Tools for computational analysis of moving boundary problems in cellular mechanobiology

Traveling and standing waves mediate pattern formation in cellular protrusions

Two complementary, local excitation, global inhibition mechanisms acting in parallel can explain the chemoattractant-induced regulation of PI(3,4,5)P3 response in dictyostelium cells.

Understanding the cooperative interaction between myosin II and actin cross-linkers mediated by actin filaments during mechanosensation

Wave patterns organize cellular protrusions and control cortical dynamics

tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis