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List of works by Carsten Kötting

A Charge-Transfer Complex of Xenon and Difluorovinylidene

scholarly article by Carsten Kötting et al published January 1998 in Journal of the American Chemical Society

A modified infrared spectrometer with high time resolution and its application for investigating fast conformational changes of the GTPase Ras.

scientific article

A phosphoryl transfer intermediate in the GTPase reaction of Ras in complex with its GTPase-activating protein

scholarly article

Amyloid-β-Secondary Structure Distribution in Cerebrospinal Fluid and Blood Measured by an Immuno-Infrared-Sensor: A Biomarker Candidate for Alzheimer's Disease.

scientific article

An ATR-FTIR Sensor Unraveling the Drug Intervention of Methylene Blue, Congo Red, and Berberine on Human Tau and Aβ.

scientific article

An infrared sensor analysing label-free the secondary structure of the Abeta peptide in presence of complex fluids.

scientific article

Automated identification of subcellular organelles by coherent anti-stokes Raman scattering.

scientific article published on May 2014

Catalysis of GTP hydrolysis by small GTPases at atomic detail by integration of X-ray crystallography, experimental, and theoretical IR spectroscopy

scientific article published on 13 August 2015

Catalytic mechanism of a mammalian Rab⋅RabGAP complex in atomic detail

scientific article

Chemical Functionalization of Germanium with Dextran Brushes for Immobilization of Proteins Revealed by Attenuated Total Reflection Fourier Transform Infrared Difference Spectroscopy.

scientific article published on 8 July 2015

Coherent Dynamics in Complex Elimination Reactions: Experimental and Theoretical Femtochemistry of 1,3-Dibromopropane and Related Systems†,‡

article

Common mechanisms of catalysis in small and heterotrimeric GTPases and their respective GAPs.

scientific article published on 24 February 2017

Detailed Structure of the H2PO4––Guanosine Diphosphate Intermediate in Ras-GAP Decoded from FTIR Experiments by Biomolecular Simulations

scientific article published on 03 December 2012

Difluorosilanethione F2Si=S by Flash Vacuum Thermolysis of (F3Si)2S and by Reaction of SiS with F2 – Matrix Studies and Ab initio Calculations

Difluorovinylidene, F2CC:

Direct Observation of Resonance Motion in Complex Elimination Reactions: Femtosecond Coherent Dynamics in Reduced Space

article

Dynamics of Molecules near Ionization

article

Elucidation of Single Hydrogen Bonds in GTPases via Experimental and Theoretical Infrared Spectroscopy

scientific article published on January 2017

Evidence for the Non-Concerted Addition of Difluorovinylidene to Acetylenes

article

Femtochemistry of Norrish type-I reactions: III. Highly excited ketones--theoretical

scientific article published in January 2002

Femtochemistry of Norrish type-I reactions: IV. Highly excited ketones--experimental

scientific article published in January 2002

GTP Hydrolysis Without an Active Site Base: A Unifying Mechanism for Ras and Related GTPases

scientific article published on 26 June 2019

Heme oxygenases from Arabidopsis thaliana reveal different mechanisms of carbon monoxide binding

scientific article published on 13 December 2011

Highly stable protein immobilization via maleimido-thiol chemistry to monitor enzymatic activity

scientific article published on 01 May 2018

IR Spectra of Phosphate Ions in Aqueous Solution: Predictions of a DFT/MM Approach Compared with Observations

article published in 2004

Immobilization of Proteins in their Physiological Active State at Functionalized Thiol Monolayers on ATR-Germanium Crystals

scientific article published on 24 September 2014

Insertion of Difluorovinylidene into Hydrogen and Methane

scientific article published in 1999

Insight into catalysis of a unique GTPase reaction by a combined biochemical and FTIR approach

Integration of Fourier Transform Infrared Spectroscopy, Fluorescence Spectroscopy, Steady-state Kinetics and Molecular Dynamics Simulations of Gαi1 Distinguishes between the GTP Hydrolysis and GDP Release Mechanism

scientific article published on 15 May 2015

Label-Free Raman Spectroscopic Imaging Monitors the Integral Physiologically Relevant Drug Responses in Cancer Cells

scientific article published on 26 June 2015

Label-free identification of myopathological features with coherent anti-Stokes Raman scattering

Label-free imaging of drug distribution and metabolism in colon cancer cells by Raman microscopy

scientific article published on 15 January 2014

Label-free screening of drug-protein interactions by time-resolved Fourier transform infrared spectroscopic assays exemplified by Ras interactions

scientific article published on September 2010

Ligand-Induced Conformational Changes in HSP90 Monitored Time Resolved and Label Free-Towards a Conformational Activity Screening for Drug Discovery

scientific article published on 03 July 2018

Local Mode Analysis: Decoding IR Spectra by Visualizing Molecular Details.

scientific article published on 16 January 2017

Matrix Isolation of 3,4-Benzocyclodeca-3,7,9-triene-1,5-diyne

Mechanism of the intrinsic arginine finger in heterotrimeric G proteins

scientific article published on 28 November 2016

Membrane extraction of Rab proteins by GDP dissociation inhibitor characterized using attenuated total reflection infrared spectroscopy

scientific article published on 29 July 2013

Monitoring Protein–Ligand Interactions by Time-Resolved FTIR Difference Spectroscopy

scientific article published on 01 January 2013

Monitoring protein-ligand interactions by time-resolved FTIR difference spectroscopy

scientific article published in January 2005

Monitoring transient events in infrared spectra using local mode analysis

scientific article published on 29 October 2018

N-Ras forms dimers at POPC membranes

scientific article published on 2 October 2012

Oxidation of Difluorovinylidene

article published in 1998

Proteins in action monitored by time-resolved FTIR spectroscopy

scientific article

Raman Micro-Spectroscopic Evidence for the Metabolism of a Tyrosine Kinase Inhibitor, Neratinib, in Cancer Cells.

scientific article published on 12 April 2018

Raman Microscopic Studies of Tissues and Cells

Raman-mikrospektroskopischer Nachweis für den Metabolismus eines Tyrosinkinase-Inhibitors, Neratinib, in Krebszellen

Ras and GTPase-activating protein (GAP) drive GTP into a precatalytic state as revealed by combining FTIR and biomolecular simulations

scientific article

Reaction mechanism of adenylyltransferase DrrA from Legionella pneumophila elucidated by time-resolved fourier transform infrared spectroscopy

scientific article published on 20 June 2014

Reactions of Difluorovinylidene—A Super-Electrophilic Carbene

Reversible Immuno-Infrared Sensor for the Detection of Alzheimer's Disease Related Biomarkers

scientific article published on 10 July 2019

Secondary structure of lipidated Ras bound to a lipid bilayer

scientific article published in December 2008

Specific Substates of Ras To Interact with GAPs and Effectors: Revealed by Theoretical Simulations and FTIR Experiments.

scientific article published on 28 February 2018

Spectral histopathology of colon cancer tissue sections by Raman imaging with 532 nm excitation provides label free annotation of lymphocytes, erythrocytes and proliferating nuclei of cancer cells

scientific article published on 4 June 2013

Spectroscopic investigation of the reaction mechanism of CopB-B, the catalytic fragment from an archaeal thermophilic ATP-driven heavy metal transporter

scientific article published on 22 September 2009

Surface Change of Ras Enabling Effector Binding Monitored in Real Time at Atomic Resolution

scientific article published on 01 May 2007

Surface-Attached Polyhistidine-Tag Proteins Characterized by FTIR Difference Spectroscopy

scientific article (publication date: 15 June 2012)

Systematic approach to group-specific isotopic labeling of proteins for vibrational spectroscopy

article

The GAP arginine finger movement into the catalytic site of Ras increases the activation entropy

scholarly article

The Protonation States of GTP and GppNHp in Ras Proteins.

scientific article

The Ras dimer structure

scientific article published on 04 May 2021

The dynamics of the catalytic site in small GTPases, variations on a common motif

scientific article published on 16 May 2013

The role of magnesium for geometry and charge in GTP hydrolysis, revealed by quantum mechanics/molecular mechanics simulations

scientific article published on 17 July 2012

The specific vibrational modes of GTP in solution and bound to Ras: a detailed theoretical analysis by QM/MM simulations

article

Time-resolved FTIR spectroscopy for monitoring protein dynamics exemplified by functional studies of Ras protein bound to a lipid bilayer

article

Time-resolved FTIR studies provide activation free energy, activation enthalpy and activation entropy for GTPase reactions

Time-resolved Fourier transform infrared spectroscopy of the nucleotide-binding domain from the ATP-binding Cassette transporter MsbA: ATP hydrolysis is the rate-limiting step in the catalytic cycle

scientific article published on 16 May 2012

Tyr39 of ran preserves the Ran.GTP gradient by inhibiting GTP hydrolysis

scientific article published on 2 June 2010

Universal Method for Protein Immobilization on Chemically Functionalized Germanium Investigated by ATR-FTIR Difference Spectroscopy

scientific article published on 04 March 2013

Unraveling the Phosphocholination Mechanism of the Legionella pneumophila Enzyme AnkX.

scientific article published on 12 July 2016

Unravelling the mechanism of dual-specificity GAPs

scientific article

Virtual staining of colon cancer tissue by label-free Raman micro-spectroscopy.

scientific article published on 14 November 2016

What vibrations tell us about GTPases

scientific article

Zeitaufgelöst und markerfrei gemessene ligandeninduzierte Konformationsänderungen von HSP90 - hin zu einem Konformationsaktivitätsscreening für die Wirkstoffentwicklung

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