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List of works by Nicolaas C Gey van Pittius

A balancing act: efflux/influx in mycobacterial drug resistance

scientific article

A metabolomics approach exploring the function of the ESX-3 type VII secretion system of M. smegmatis

A metabolomics investigation of the function of the ESX-1 gene cluster in mycobacteria.

scientific article published on 12 October 2016

A regulatory variant in the C1Q gene cluster is associated with tuberculosis susceptibility and C1qA plasma levels in a South African population

scientific article published on 19 June 2020

Application of sensitive and specific molecular methods to uncover global dissemination of the major RDRio Sublineage of the Latin American-Mediterranean Mycobacterium tuberculosis spoligotype family

scientific article published on 30 January 2008

Assessing the progress of Mycobacterium tuberculosis H37Rv structural genomics.

scientific article published on 31 December 2014

Chapter 11: Acquisition, Transmission and Amplification of Drug-Resistant Tuberculosis

article

Chapter 9: Tuberculosis Recurrence: Exogenous or Endogenous?

Characterization of Mycobacterium orygis

scientific article published on October 2012

Clinical Relevance of Nontuberculous Mycobacteria Isolated from Sputum in a Gold Mining Workforce in South Africa: An Observational, Clinical Study

scientific article published on 28 May 2015

Comparative Genomics and Proteomic Analysis of Four Non-tuberculous Mycobacterium Species and Mycobacterium tuberculosis Complex: Occurrence of Shared Immunogenic Proteins

scientific article

Comparative analysis of Mycobacterium tuberculosis pe and ppe genes reveals high sequence variation and an apparent absence of selective constraints

scientific article published on 4 April 2012

Detection of Mycobacterium kansasii infection in a rhesus macaque (Macaca mulatta) using a modified QuantiFERON-TB Gold assay

scientific article published on 30 March 2010

Detection of Mycobacterium tuberculosis infection in dogs in a high-risk setting

scientific article published on 19 April 2011

Discordance between mycobacterial interspersed repetitive-unit-variable-number tandem-repeat typing and IS6110 restriction fragment length polymorphism genotyping for analysis of Mycobacterium tuberculosis Beijing strains in a setting of high incide

scientific article published on 20 August 2008

ESAT-6 and CFP-10: what is the diagnosis?

scientific article published on November 2002

Emergence and treatment of multidrug resistant (MDR) and extensively drug-resistant (XDR) tuberculosis in South Africa

scientific article published on 04 August 2011

Evaluation of the Capilia TB assay for culture confirmation of Mycobacterium tuberculosis infections in Zambia and South Africa

scientific article published on 4 August 2010

Evidence for a rapid rate of molecular evolution at the hypervariable and immunogenic Mycobacterium tuberculosis PPE38 gene region

scientific article

Evidence that the Spread of Mycobacterium tuberculosis Strains with the Beijing Genotype Is Human Population Dependent.

scientific article published in July 2011

Evolution and expansion of the Mycobacterium tuberculosis PE and PPE multigene families and their association with the duplication of the ESAT-6 (esx) gene cluster regions

scientific article

Expression and production of soluble Mycobacterium tuberculosis H37Rv mycosin-3.

scientific article published on 6 February 2016

Fluorometric assay for testing rifampin susceptibility of Mycobacterium tuberculosis complex.

scientific article published on 27 February 2008

Frequent homologous recombination events in Mycobacterium tuberculosis PE/PPE multigene families: potential role in antigenic variability

scientific article published on 26 September 2008

Genotype MTBDRsl line probe assay shortens time to diagnosis of extensively drug-resistant tuberculosis in a high-throughput diagnostic laboratory

scientific article published on 18 October 2012

Geospatial distribution of Mycobacterium tuberculosis genotypes in Africa

scientific article published in PLoS ONE

Independent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region

scientific article

Infection of African buffalo (Syncerus caffer) by oryx bacillus, a rare member of the antelope clade of the Mycobacterium tuberculosis complex

scientific article published in October 2012

Insertion element IS6110-based restriction fragment length polymorphism genotyping of Mycobacterium tuberculosis

scientific article

Insights into the evolutionary history of tubercle bacilli as disclosed by genetic rearrangements within a PE_PGRS duplicated gene pair ⬇️

scientific article

Iron acquisition strategies in mycobacteria.

scientific article

Mixed infections of Corynebacterium pseudotuberculosis and non-tuberculous mycobacteria in South African antelopes presenting with tuberculosis-like lesions

scientific article published on 24 July 2010

Modification of the QuantiFERON-TB Gold (In-Tube) assay for the diagnosis of Mycobacterium bovis infection in African buffaloes (Syncerus caffer)

scientific article published on 20 April 2011

Molecular Epidemiological Interpretation of the Epidemic of Extensively Drug-Resistant Tuberculosis in South Africa.

scientific article

Moxifloxacin retains antimycobacterial activity in the presence of gyrA mutations

scientific article published on 10 February 2014

Multiple, independent, identical IS6110 insertions in Mycobacterium tuberculosis PPE genes

article

Mutation rate and the emergence of drug resistance in Mycobacterium tuberculosis.

scientific article published on 26 September 2013

Mutations in the rrs A1401G Gene and Phenotypic Resistance to Amikacin and Capreomycin in Mycobacterium tuberculosis

article

Mycobacteria and disease in southern Africa

scientific article

Mycobacterial interspersed repetitive-unit-variable-number tandem-repeat analysis and Beijing/W family of Mycobacterium tuberculosis.

scientific article published on July 2011

Mycobacterium tuberculosis Beijing genotype: a template for success.

scientific article published on 10 August 2011

Mycobacterium tuberculosis Population Structure Determines the Outcome of Genetics-Based Second-Line Drug Resistance Testing ⬇️

scientific article published on February 13, 2012

Mycobacterium tuberculosis strains with the Beijing genotype demonstrate variability in virulence associated with transmission.

scientific article

Mycosin-1, a subtilisin-like serine protease of Mycobacterium tuberculosis, is cell wall-associated and expressed during infection of macrophages.

scientific article

Novel Mycobacterium tuberculosis complex pathogen, M. mungi

scientific article

Novel cause of tuberculosis in meerkats, South Africa

scientific article published on December 2013

PPE and PE_PGRS proteins ofMycobacterium marinumare transported via the type VII secretion system ESX-5

scientific article published on 07 July 2009

Patients with active tuberculosis often have different strains in the same sputum specimen

scientific article published on 30 December 2003

Phage-based detection of bacterial pathogens.

scientific article published on June 2014

Phosphoproteomics analysis of a clinical Mycobacterium tuberculosis Beijing isolate: expanding the mycobacterial phosphoproteome catalog

scientific article

Population structure of mixed Mycobacterium tuberculosis infection is strain genotype and culture medium dependent

scientific article

Prevalence and distribution of non-tuberculous mycobacteria (NTM) in cattle, African buffaloes (Syncerus caffer) and their environments in South Africa

scientific article published on November 2013

Progenitor strain introduction of Mycobacterium bovis at the wildlife-livestock interface can lead to clonal expansion of the disease in a single ecosystem.

scientific article published on 12 April 2017

Programmatically selected multidrug-resistant strains drive the emergence of extensively drug-resistant tuberculosis in South Africa

scientific article (publication date: 2013)

Proteogenomic Investigation of Strain Variation in Clinical Mycobacterium tuberculosis Isolates

scientific article published on 18 August 2017

Pulmonary infection due to Mycobacterium bovis in a black rhinoceros (Diceros bicornis minor) in South Africa

scientific article published in October 2009

Pulmonary infection due to the dassie bacillus (Mycobacterium tuberculosis complex sp.) in a free-living dassie (rock hyrax-Procavia capensis) from South Africa

scientific article published on 22 October 2007

Recombination in pe/ppe genes contributes to genetic variation in Mycobacterium tuberculosis lineages

scientific article

Rifampicin reduces susceptibility to ofloxacin in rifampicin-resistant Mycobacterium tuberculosis through efflux

scientific article published on 21 April 2011

Safe Mycobacterium tuberculosis DNA extraction method that does not compromise integrity

scientific article published in January 2006

Spectrum of non-tuberculous mycobacteria identified using standard biochemical testing vs. 16S sequencing.

scientific article

Systematic genetic nomenclature for type VII secretion systems.

scientific article

The clinical relevance of Mycobacterial pharmacogenetics.

scientific article published in May 2009

The complex architecture of mycobacterial promoters.

scientific article published on 25 September 2012

The diagnostic performance of the GenoType MTBDRplus version 2 line probe assay is equivalent to that of the Xpert MTB/RIF assay

scientific article

The non-clonality of drug resistance in Beijing-genotype isolates of Mycobacterium tuberculosis from the Western Cape of South Africa

scientific article

The plasmid-mediated evolution of the mycobacterial ESX (Type VII) secretion systems

scientific article

The role of IS6110 in the evolution of Mycobacterium tuberculosis

scientific article published on 12 July 2007

Two promoters in the esx-3 gene cluster of Mycobacterium smegmatis respond inversely to different iron concentrations in vitro.

scientific article published on 25 August 2017

Type VII secretion--mycobacteria show the way.

scientific article published in November 2007

Whole genome sequence analysis of Mycobacterium suricattae.

scientific article

Zoonotic tuberculosis and brucellosis in Africa: neglected zoonoses or minor public-health issues? The outcomes of a multi-disciplinary workshop.

scientific article

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