Search filters

List of works by Tobias L. Lenz

A field reciprocal transplant experiment reveals asymmetric costs of migration between lake and river ecotypes of three-spined sticklebacks (Gasterosteus aculeatus).

scientific article

Adaptive value of novel MHC immune gene variants

scientific article published on 31 January 2018

Additive and interaction effects at three amino acid positions in HLA-DQ and HLA-DR molecules drive type 1 diabetes risk

scientific article

Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans.

scientific article

Computational prediction of MHC II-antigen binding supports divergent allele advantage and explains trans-species polymorphism.

scientific article published on 20 April 2011

Cryptic haplotype-specific gamete selection yields offspring with optimal MHC immune genes

scientific article published on 24 September 2018

Disentangling the role of MHC-dependent 'good genes' and 'compatible genes' in mate-choice decisions of three-spined sticklebacks Gasterosteus aculeatus under semi-natural conditions

scientific article published in November 2009

Divergent Allele Advantage at Human MHC Genes: Signatures of Past and Ongoing Selection

scientific article published on 01 September 2018

Divergent allele advantage at MHC-DRB through direct and maternal genotypic effects and its consequences for allele pool composition and mating.

scientific article published on 7 July 2013

Divergent selection on locally adapted major histocompatibility complex immune genes experimentally proven in the field.

scientific article

Diverse MHC IIB allele repertoire increases parasite resistance and body condition in the Long-tailed giant rat (Leopoldamys sabanus).

scientific article

Evaluating patterns of convergent evolution and trans-species polymorphism at MHC immunogenes in two sympatric stickleback species

scientific article

Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy

scientific article published on 07 November 2019

Excess of Deleterious Mutations around HLA Genes Reveals Evolutionary Cost of Balancing Selection.

scientific article published on 28 June 2016

Experimental parasite infection reveals costs and benefits of paternal effects.

scientific article

Exploring local immunological adaptation of two stickleback ecotypes by experimental infection and transcriptome-wide digital gene expression analysis.

scientific article

Extensive copy-number variation of young genes across stickleback populations

scientific article

Genes with monoallelic expression contribute disproportionately to genetic diversity in humans

scientific article published on 25 January 2016

Genome analysis reveals insights into physiology and longevity of the Brandt's bat Myotis brandtii

scientific article

Genome-wide patterns of standing genetic variation in a marine population of three-spined sticklebacks

scientific article

Genome-wide study of a Neolithic Wartberg grave community reveals distinct HLA variation and hunter-gatherer ancestry

scientific article published on 25 January 2021

Genomics of divergence along a continuum of parapatric population differentiation

scientific article

HIV peptidome-wide association study reveals patient-specific epitope repertoires associated with HIV control

scientific article published on 02 January 2019

Human leukocyte antigen variation is associated with adverse events of checkpoint inhibitors

scientific article published on 07 December 2018

Induction of diploid gynogenesis in an evolutionary model organism, the three-spined stickleback (Gasterosteus aculeatus).

scientific article

MHC-based mate choice combines good genes and maintenance of MHC polymorphism

scientific article published on 11 June 2009

Major histocompatibility complex polymorphism: dynamics and consequences of parasite‐mediated local adaptation in fishes ⬇️

scientific article published on December 1, 2010

Pathogen diversity drives the evolution of generalist MHC-II alleles in human populations

scientific article published on 31 January 2019

Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load

scientific article

RSCA genotyping of MHC for high-throughput evolutionary studies in the model organism three-spined stickleback Gasterosteus aculeatus

scientific article

Rapid and adaptive evolution of MHC genes under parasite selection in experimental vertebrate populations

scientific article

Simple approach to reduce PCR artefact formation leads to reliable genotyping of MHC and other highly polymorphic loci--implications for evolutionary analysis

scientific article published on 24 September 2008

Speciation accelerated and stabilized by pleiotropic major histocompatibility complex immunogenes

scientific article published in January 2009

The One Past Health workshop: connecting ancient DNA and zoonosis research.

scientific article published on 8 June 2017

The contribution of post-copulatory mechanisms to incipient ecological speciation in sticklebacks.

scientific article

Transcription in space--environmental vs. genetic effects on differential immune gene expression

scientific article published in September 2015

Transcriptome profiling of immune tissues reveals habitat-specific gene expression between lake and river sticklebacks

scientific article published on 7 January 2016

Uterine selection for immunocompetent offspring ⬇️

scientific article published on June 14, 2011

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases

scientific article

Paulina is supported by:

About Paulina

Help